Asthma protection with bacteria - Science or fiction?

Thorax

Volumn 66, Issue 9, 2011, Pages 744-745

  Renz, Harald ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARABINOGALACTAN; LIPOPOLYSACCHARIDE; PATTERN RECOGNITION RECEPTOR; TOLL LIKE RECEPTOR;

ASTHMA; BACTERIUM; EDITORIAL; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; HUMAN; IMMUNE RESPONSE; LUNG FUNCTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

EID: 80051868277     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thx.2011.160853     Document Type: Editorial

References (14)

1. Braun-Fahrlander C., Riedler J., Herz U., et al. Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med 2002;347:869-877
2. Blumer N., Herz U., Wegmann M., et al. Prenatal lipopolysaccharide- exposure prevents allergic sensitization and airway inflammation, but not airway responsiveness in a murine model of experimental asthma. Clin Exp Allergy 2005;35:397-402. (Pubitemid 40516669)
3. Gerhold K., Bluemchen K., Franke A., et al. Exposure to endotoxin and allergen in early life and its effect on allergen sensitization in mice. J Allergy Clin Immunol 2003;112:389-396 (Pubitemid 36981381)
4. Eisenbarth S.C., Piggott D.A., Huleatt J.W., et al. Lipopolysaccharide- enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med 2002;196:1645-1651 (Pubitemid 36026476)
5. Debarry J., Garn H., Hanuszkiewicz A., et al. Acinetobacter lwoffii and Lactococcus lactis strains isolated from farm cowsheds possess strong allergy-protective properties. J Allergy Clin Immunol 2007;119:1514-1521 (Pubitemid 46863371)
6. Blumer N., Sel S., Virna S., et al. Perinatal maternal application of Lactobacillus rhamnosus GG suppresses allergic airway inflammation in mouse offspring. Clin Exp Allergy 2007;37:348-357 (Pubitemid 46393247)
7. Vogel K., Blumer N., Korthals M., et al. Animal shed Bacillus licheniformis spores possess allergy-protective as well as inflammatory properties. J Allergy Clin Immunol 2008;122:307-12, 312.e1-8.
8. Peters M., Kauth M., Scherner O., et al. Arabinogalactan isolated from cowshed dust extract protects mice from allergic airway inflammation and sensitization. J Allergy Clin Immunol 2010;126:648-56, e1-4.
9. Patel M., Xu D., Kewin P., et al. TLR2 agonist ameliorates established allergic airway inflammation by promoting Th1 response and not via regulatory T cells. J Immunol 2005;174:7558-7563 (Pubitemid 40806259)
10. Sel S., Wegmann M., Sel S., et al. Immunomodulatory effects of viral TLR ligands on experimental asthma depend on the additive effects of IL-12 and IL-10. J Immunol 2007;178:7805-7813 (Pubitemid 46898052)
11. Kim Y.S., Kwon K.S., Kim D.K., et al. Inhibition of murine allergic airway disease by Bordetella pertussis. Immunology 2004;112:624-630
12. Lauener R.P., Birchler T., Adamski J., et al, ALEX study group. Expression of CD14 and Toll-like receptor 2 in farmers' and non-farmers' children. Lancet 2002;360:465-466 (Pubitemid 34880149)
13. Ege M.J., Bieli C., Frei R., et al, Parsifal Study team. Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children. J Allergy Clin Immunol 2006;117:817-823
14. Nembrini C., Sichelstiel A., Kisielow J., et al. Bacterial-induced protection against allergic inflammation through a multicomponent immunregulatory mechanism. Thorax 2011;66:755-763