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Volumn 17, Issue 9, 2011, Pages 386-394

Prognostic markers in colorectal pathology: Is morphology enough?

Author keywords

Biomarkers; Colorectal cancer; Morphology; Prognostic markers

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; RAS PROTEIN;

EID: 80051863620     PISSN: 17562317     EISSN: 18767621     Source Type: Journal    
DOI: 10.1016/j.mpdhp.2011.06.016     Document Type: Article
Times cited : (8)

References (71)
  • 1
    • 77949437015 scopus 로고    scopus 로고
    • Colorectal cancer
    • M 20
    • Cunningham D., Atkin W., Lenz H.J., et al. Colorectal cancer. Lancet 2010 Mar 20, 375:1030-1047.
    • (2010) Lancet , vol.375 , pp. 1030-1047
    • Cunningham, D.1    Atkin, W.2    Lenz, H.J.3
  • 2
    • 0034952103 scopus 로고    scopus 로고
    • Microarrays - the 21st century divining rod?
    • He Y.D., Friend S.H. Microarrays - the 21st century divining rod?. Nat Med 2001 Jun, 7:658-659.
    • (2001) Nat Med , vol.7 , pp. 658-659
    • He, Y.D.1    Friend, S.H.2
  • 3
    • 0035750552 scopus 로고    scopus 로고
    • Classification in anatomic pathology
    • Foucar E. Classification in anatomic pathology. Am J Clin Pathol 2001 Dec, 116(suppl):S5-S20.
    • (2001) Am J Clin Pathol , vol.116 , Issue.SUPPL.
    • Foucar, E.1
  • 5
    • 0035871356 scopus 로고    scopus 로고
    • Prognostic factors in clinical decision making: the future
    • A 15
    • Gospodarowicz M., Mackillop W., O'Sullivan B., et al. Prognostic factors in clinical decision making: the future. Cancer 2001 Apr 15, 91(8 suppl):1688-1695.
    • (2001) Cancer , vol.91 , Issue.8 SUPPL. , pp. 1688-1695
    • Gospodarowicz, M.1    Mackillop, W.2    O'Sullivan, B.3
  • 7
    • 77953228914 scopus 로고    scopus 로고
    • TNM staging system of colorectal carcinoma: a critical appraisal of challenging issues
    • Puppa G., Sonzogni A., Colombari R., Pelosi G. TNM staging system of colorectal carcinoma: a critical appraisal of challenging issues. Arch Pathol Lab Med 2010 Jun, 134:837-852.
    • (2010) Arch Pathol Lab Med , vol.134 , pp. 837-852
    • Puppa, G.1    Sonzogni, A.2    Colombari, R.3    Pelosi, G.4
  • 8
    • 79958170918 scopus 로고    scopus 로고
    • TNM staging system of colorectal carcinoma: surgical pathology
    • Puppa G. TNM staging system of colorectal carcinoma: surgical pathology. Diagn Histopathol 2011 Jun, 17:243-262.
    • (2011) Diagn Histopathol , vol.17 , pp. 243-262
    • Puppa, G.1
  • 9
    • 0022218071 scopus 로고
    • The President's cancer, the Dukes classification, and confusion
    • Kyriakos M. The President's cancer, the Dukes classification, and confusion. Arch Pathol Lab Med 1985 Dec, 109:1063-1066.
    • (1985) Arch Pathol Lab Med , vol.109 , pp. 1063-1066
    • Kyriakos, M.1
  • 10
    • 78651334389 scopus 로고    scopus 로고
    • Quality assurance in pathology in colorectal cancer screening and diagnosis-European recommendations
    • Quirke P., Risio M., Lambert R., von Karsa L., Vieth M. Quality assurance in pathology in colorectal cancer screening and diagnosis-European recommendations. Virchows Arch 2011 Jan, 458:1-19.
    • (2011) Virchows Arch , vol.458 , pp. 1-19
    • Quirke, P.1    Risio, M.2    Lambert, R.3    von Karsa, L.4    Vieth, M.5
  • 13
    • 0038360113 scopus 로고    scopus 로고
    • Lipincott-Raven, Philadelphia, I. Fleming, J. Cooper, D. Hensen (Eds.)
    • AJCC cancer staging manual 1997, Lipincott-Raven, Philadelphia. 5th edn. I. Fleming, J. Cooper, D. Hensen (Eds.).
    • (1997) AJCC cancer staging manual
  • 15
    • 64249099411 scopus 로고    scopus 로고
    • Springer, S. Edge, D. Byrd, C. Compton, A. Fritz, F. Greene, A. Trotti (Eds.)
    • AJCC cancer staging manual 2010, Springer. S. Edge, D. Byrd, C. Compton, A. Fritz, F. Greene, A. Trotti (Eds.).
    • (2010) AJCC cancer staging manual
  • 16
    • 0141678112 scopus 로고    scopus 로고
    • TNM staging for malignancies of the digestive tract: 2003 changes and beyond
    • Greene F.L. TNM staging for malignancies of the digestive tract: 2003 changes and beyond. Semin Surg Oncol 2003, 21:23-29.
    • (2003) Semin Surg Oncol , vol.21 , pp. 23-29
    • Greene, F.L.1
  • 18
    • 73449096766 scopus 로고    scopus 로고
    • Heterogeneity of pT3 colorectal carcinomas according to the depth of invasion
    • Bori R., Sejben I., Svebis M., et al. Heterogeneity of pT3 colorectal carcinomas according to the depth of invasion. Pathol Oncol Res 2009 Sep, 15:527-532.
    • (2009) Pathol Oncol Res , vol.15 , pp. 527-532
    • Bori, R.1    Sejben, I.2    Svebis, M.3
  • 20
    • 0036288122 scopus 로고    scopus 로고
    • Identification of objective pathological prognostic determinants and models of prognosis in Dukes' B colon cancer
    • Petersen V.C., Baxter K.J., Love S.B., Shepherd N.A. Identification of objective pathological prognostic determinants and models of prognosis in Dukes' B colon cancer. Gut 2002 Jul, 51:65-69.
    • (2002) Gut , vol.51 , pp. 65-69
    • Petersen, V.C.1    Baxter, K.J.2    Love, S.B.3    Shepherd, N.A.4
  • 21
    • 0030987864 scopus 로고    scopus 로고
    • The prognostic importance of peritoneal involvement in colonic cancer: a prospective evaluation
    • Shepherd N.A., Baxter K.J., Love S.B. The prognostic importance of peritoneal involvement in colonic cancer: a prospective evaluation. Gastroenterology 1997 Apr, 112:1096-1102.
    • (1997) Gastroenterology , vol.112 , pp. 1096-1102
    • Shepherd, N.A.1    Baxter, K.J.2    Love, S.B.3
  • 22
    • 85047688464 scopus 로고    scopus 로고
    • Peritoneal involvement in stage II colon cancer
    • Lennon A.M., Mulcahy H.E., Hyland J.M., et al. Peritoneal involvement in stage II colon cancer. Am J Clin Pathol 2003 Jan, 119:108-113.
    • (2003) Am J Clin Pathol , vol.119 , pp. 108-113
    • Lennon, A.M.1    Mulcahy, H.E.2    Hyland, J.M.3
  • 23
    • 77956201748 scopus 로고    scopus 로고
    • Peritoneal elastic laminal invasion of colorectal cancer: the diagnostic utility and clinicopathologic relationship
    • Kojima M., Nakajima K., Ishii G., Saito N., Ochiai A. Peritoneal elastic laminal invasion of colorectal cancer: the diagnostic utility and clinicopathologic relationship. Am J Surg Pathol 2010 Sep, 34:1351-1360.
    • (2010) Am J Surg Pathol , vol.34 , pp. 1351-1360
    • Kojima, M.1    Nakajima, K.2    Ishii, G.3    Saito, N.4    Ochiai, A.5
  • 24
    • 79953046403 scopus 로고    scopus 로고
    • Peritoneal elastic lamina invasion in colorectal cancer: the answer to a controversial area of pathology?
    • author reply 8-9
    • Puppa G., Shepherd N.A., Sheahan K., Stewart C.J. Peritoneal elastic lamina invasion in colorectal cancer: the answer to a controversial area of pathology?. Am J Surg Pathol 2011 Mar, 35:465-468. author reply 8-9.
    • (2011) Am J Surg Pathol , vol.35 , pp. 465-468
    • Puppa, G.1    Shepherd, N.A.2    Sheahan, K.3    Stewart, C.J.4
  • 26
    • 77953024250 scopus 로고    scopus 로고
    • The prognostic value of lymph node ratio in a population-based collective of colorectal cancer patients
    • Rosenberg R., Engel J., Bruns C., et al. The prognostic value of lymph node ratio in a population-based collective of colorectal cancer patients. Ann Surg 2010 Jun, 251:1070-1078.
    • (2010) Ann Surg , vol.251 , pp. 1070-1078
    • Rosenberg, R.1    Engel, J.2    Bruns, C.3
  • 27
    • 12344307199 scopus 로고    scopus 로고
    • Number of lymph nodes examined and prognosis of TNM stage II colorectal cancer
    • Sarli L., Bader G., Iusco D., et al. Number of lymph nodes examined and prognosis of TNM stage II colorectal cancer. Eur J Cancer 2005 Jan, 41:272-279.
    • (2005) Eur J Cancer , vol.41 , pp. 272-279
    • Sarli, L.1    Bader, G.2    Iusco, D.3
  • 28
    • 0038472209 scopus 로고    scopus 로고
    • Accuracy of determining nodal negativity in colorectal cancer on the basis of the number of nodes retrieved on resection
    • Joseph N.E., Sigurdson E.R., Hanlon A.L., et al. Accuracy of determining nodal negativity in colorectal cancer on the basis of the number of nodes retrieved on resection. Ann Surg Oncol 2003 Apr, 10:213-218.
    • (2003) Ann Surg Oncol , vol.10 , pp. 213-218
    • Joseph, N.E.1    Sigurdson, E.R.2    Hanlon, A.L.3
  • 29
    • 0036208767 scopus 로고    scopus 로고
    • Prognostic evaluation of stage B colon cancer patients is improved by an adequate lymphadenectomy: results of a secondary analysis of a large scale adjuvant trial
    • Prandi M., Lionetto R., Bini A., et al. Prognostic evaluation of stage B colon cancer patients is improved by an adequate lymphadenectomy: results of a secondary analysis of a large scale adjuvant trial. Ann Surg 2002 Apr, 235:458-463.
    • (2002) Ann Surg , vol.235 , pp. 458-463
    • Prandi, M.1    Lionetto, R.2    Bini, A.3
  • 30
    • 78650794897 scopus 로고    scopus 로고
    • Clinicopathological staging of colorectal cancer: evolution and consensus - an Australian perspective
    • Chapuis P.H., Chan C., Dent O.F. Clinicopathological staging of colorectal cancer: evolution and consensus - an Australian perspective. J Gastroenterol Hepatol 2011 Jan, 26(suppl 1):58-64.
    • (2011) J Gastroenterol Hepatol , vol.26 , Issue.SUPPL. 1 , pp. 58-64
    • Chapuis, P.H.1    Chan, C.2    Dent, O.F.3
  • 31
    • 58149386920 scopus 로고    scopus 로고
    • Prognosis of patients with colorectal cancer is associated with lymph node ratio: a single-center analysis of 3,026 patients over a 25-year time period
    • Rosenberg R., Friederichs J., Schuster T., et al. Prognosis of patients with colorectal cancer is associated with lymph node ratio: a single-center analysis of 3,026 patients over a 25-year time period. Ann Surg 2008 Dec, 248:968-978.
    • (2008) Ann Surg , vol.248 , pp. 968-978
    • Rosenberg, R.1    Friederichs, J.2    Schuster, T.3
  • 32
    • 36849064682 scopus 로고    scopus 로고
    • Adjuvant chemotherapy versus observation in patients with colorectal cancer: a randomised study
    • D 15
    • Gray R., Barnwell J., McConkey C., Hills R.K., Williams N.S., Kerr D.J. Adjuvant chemotherapy versus observation in patients with colorectal cancer: a randomised study. Lancet 2007 Dec 15, 370:2020-2029.
    • (2007) Lancet , vol.370 , pp. 2020-2029
    • Gray, R.1    Barnwell, J.2    McConkey, C.3    Hills, R.K.4    Williams, N.S.5    Kerr, D.J.6
  • 33
    • 4344587783 scopus 로고    scopus 로고
    • American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer
    • A 15
    • Benson A.B., Schrag D., Somerfield M.R., et al. American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer. J Clin Oncol 2004 Aug 15, 22:3408-3419.
    • (2004) J Clin Oncol , vol.22 , pp. 3408-3419
    • Benson, A.B.1    Schrag, D.2    Somerfield, M.R.3
  • 34
    • 0034177501 scopus 로고    scopus 로고
    • American Joint Committee on Cancer Prognostic Factors Consensus Conference: Colorectal Working Group
    • A 1
    • Compton C., Fenoglio-Preiser C.M., Pettigrew N., Fielding L.P. American Joint Committee on Cancer Prognostic Factors Consensus Conference: Colorectal Working Group. Cancer 2000 Apr 1, 88:1739-1757.
    • (2000) Cancer , vol.88 , pp. 1739-1757
    • Compton, C.1    Fenoglio-Preiser, C.M.2    Pettigrew, N.3    Fielding, L.P.4
  • 36
    • 70350450358 scopus 로고    scopus 로고
    • Evaluation of venous invasion by Elastica van Gieson stain and tumor budding predicts local and distant metastases in patients with T1 stage colorectal cancer
    • Suzuki A., Togashi K., Nokubi M., et al. Evaluation of venous invasion by Elastica van Gieson stain and tumor budding predicts local and distant metastases in patients with T1 stage colorectal cancer. Am J Surg Pathol 2009 Nov, 33:1601-1607.
    • (2009) Am J Surg Pathol , vol.33 , pp. 1601-1607
    • Suzuki, A.1    Togashi, K.2    Nokubi, M.3
  • 37
    • 70349897686 scopus 로고    scopus 로고
    • Interobserver variation in the reporting of local peritoneal involvement and extramural venous invasion in colonic cancer
    • Littleford S.E., Baird A., Rotimi O., Verbeke C.S., Scott N. Interobserver variation in the reporting of local peritoneal involvement and extramural venous invasion in colonic cancer. Histopathology 2009 Oct, 55:407-413.
    • (2009) Histopathology , vol.55 , pp. 407-413
    • Littleford, S.E.1    Baird, A.2    Rotimi, O.3    Verbeke, C.S.4    Scott, N.5
  • 38
    • 58749103858 scopus 로고    scopus 로고
    • Lymphovascular invasion in colorectal cancer: an interobserver variability study
    • Harris E.I., Lewin D.N., Wang H.L., et al. Lymphovascular invasion in colorectal cancer: an interobserver variability study. Am J Surg Pathol 2008 Dec, 32:1816-1821.
    • (2008) Am J Surg Pathol , vol.32 , pp. 1816-1821
    • Harris, E.I.1    Lewin, D.N.2    Wang, H.L.3
  • 39
    • 32544458830 scopus 로고    scopus 로고
    • Detection of venous invasion in surgical specimens of colorectal carcinoma: the efficacy of various types of tissue blocks
    • Sternberg A., Mizrahi A., Amar M., Groisman G. Detection of venous invasion in surgical specimens of colorectal carcinoma: the efficacy of various types of tissue blocks. J Clin Pathol 2006 Feb, 59:207-210.
    • (2006) J Clin Pathol , vol.59 , pp. 207-210
    • Sternberg, A.1    Mizrahi, A.2    Amar, M.3    Groisman, G.4
  • 40
    • 77950212481 scopus 로고    scopus 로고
    • Objective criteria for the grading of venous invasion in colorectal cancer
    • Sato T., Ueno H., Mochizuki H., et al. Objective criteria for the grading of venous invasion in colorectal cancer. Am J Surg Pathol 2010 Apr, 34:454-462.
    • (2010) Am J Surg Pathol , vol.34 , pp. 454-462
    • Sato, T.1    Ueno, H.2    Mochizuki, H.3
  • 41
    • 70449707511 scopus 로고    scopus 로고
    • Perineural invasion is an independent predictor of outcome in colorectal cancer
    • N 1
    • Liebig C., Ayala G., Wilks J., et al. Perineural invasion is an independent predictor of outcome in colorectal cancer. J Clin Oncol 2009 Nov 1, 27:5131-5137.
    • (2009) J Clin Oncol , vol.27 , pp. 5131-5137
    • Liebig, C.1    Ayala, G.2    Wilks, J.3
  • 42
    • 77955284630 scopus 로고    scopus 로고
    • Perineural invasion: correlation with aggressive phenotype and independent prognostic variable in both colon and rectum cancer
    • author reply e61-2, J 20
    • Poeschl E.M., Pollheimer M.J., Kornprat P., et al. Perineural invasion: correlation with aggressive phenotype and independent prognostic variable in both colon and rectum cancer. J Clin Oncol 2010 Jul 20, 28:e358-e360. author reply e61-2.
    • (2010) J Clin Oncol , vol.28
    • Poeschl, E.M.1    Pollheimer, M.J.2    Kornprat, P.3
  • 43
    • 68149170070 scopus 로고    scopus 로고
    • Perineural invasion in cancer: a review of the literature
    • A 1
    • Liebig C., Ayala G., Wilks J.A., Berger D.H., Albo D. Perineural invasion in cancer: a review of the literature. Cancer 2009 Aug 1, 115:3379-3391.
    • (2009) Cancer , vol.115 , pp. 3379-3391
    • Liebig, C.1    Ayala, G.2    Wilks, J.A.3    Berger, D.H.4    Albo, D.5
  • 44
    • 78349293437 scopus 로고    scopus 로고
    • The severity of neural invasion is a crucial prognostic factor in rectal cancer independent of neoadjuvant radiochemotherapy
    • Ceyhan G.O., Liebl F., Maak M., et al. The severity of neural invasion is a crucial prognostic factor in rectal cancer independent of neoadjuvant radiochemotherapy. Ann Surg 2010 Nov, 252:797-804.
    • (2010) Ann Surg , vol.252 , pp. 797-804
    • Ceyhan, G.O.1    Liebl, F.2    Maak, M.3
  • 45
    • 0023213901 scopus 로고
    • A new prognostic classification of rectal cancer
    • J 6
    • Jass J.R., Love S.B., Northover J.M. A new prognostic classification of rectal cancer. Lancet 1987 Jun 6, 1:1303-1306.
    • (1987) Lancet , vol.1 , pp. 1303-1306
    • Jass, J.R.1    Love, S.B.2    Northover, J.M.3
  • 46
    • 14844310372 scopus 로고    scopus 로고
    • Perineural and vascular invasion in oral cavity squamous carcinoma: increased incidence on re-review of slides and by using immunohistochemical enhancement
    • Kurtz K.A., Hoffman H.T., Zimmerman M.B., Robinson R.A. Perineural and vascular invasion in oral cavity squamous carcinoma: increased incidence on re-review of slides and by using immunohistochemical enhancement. Arch Pathol Lab Med 2005 Mar, 129:354-359.
    • (2005) Arch Pathol Lab Med , vol.129 , pp. 354-359
    • Kurtz, K.A.1    Hoffman, H.T.2    Zimmerman, M.B.3    Robinson, R.A.4
  • 47
    • 33845599552 scopus 로고    scopus 로고
    • Tumour budding in colorectal carcinoma
    • Prall F. Tumour budding in colorectal carcinoma. Histopathology 2007 Jan, 50:151-162.
    • (2007) Histopathology , vol.50 , pp. 151-162
    • Prall, F.1
  • 48
    • 22144436288 scopus 로고    scopus 로고
    • Tumour budding as prognostic factor in stage I/II colorectal carcinoma
    • Prall F., Nizze H., Barten M. Tumour budding as prognostic factor in stage I/II colorectal carcinoma. Histopathology 2005 Jul, 47:17-24.
    • (2005) Histopathology , vol.47 , pp. 17-24
    • Prall, F.1    Nizze, H.2    Barten, M.3
  • 49
    • 0042529110 scopus 로고    scopus 로고
    • Tumor budding at the invasive margin can predict patients at high risk of recurrence after curative surgery for stage II, T3 colon cancer
    • Tanaka M., Hashiguchi Y., Ueno H., Hase K., Mochizuki H. Tumor budding at the invasive margin can predict patients at high risk of recurrence after curative surgery for stage II, T3 colon cancer. Dis Colon Rectum 2003 Aug, 46:1054-1059.
    • (2003) Dis Colon Rectum , vol.46 , pp. 1054-1059
    • Tanaka, M.1    Hashiguchi, Y.2    Ueno, H.3    Hase, K.4    Mochizuki, H.5
  • 50
    • 59149092031 scopus 로고    scopus 로고
    • Tumor budding is a strong and reproducible prognostic marker in T3N0 colorectal cancer
    • Wang L.M., Kevans D., Mulcahy H., et al. Tumor budding is a strong and reproducible prognostic marker in T3N0 colorectal cancer. Am J Surg Pathol 2009 Jan, 33:134-141.
    • (2009) Am J Surg Pathol , vol.33 , pp. 134-141
    • Wang, L.M.1    Kevans, D.2    Mulcahy, H.3
  • 52
    • 4143061403 scopus 로고    scopus 로고
    • Risk factors for an adverse outcome in early invasive colorectal carcinoma
    • Ueno H., Mochizuki H., Hashiguchi Y., et al. Risk factors for an adverse outcome in early invasive colorectal carcinoma. Gastroenterology 2004 Aug, 127:385-394.
    • (2004) Gastroenterology , vol.127 , pp. 385-394
    • Ueno, H.1    Mochizuki, H.2    Hashiguchi, Y.3
  • 53
    • 33745223503 scopus 로고    scopus 로고
    • Actual number of tumor budding as a new tool for the individualization of treatment of T1 colorectal carcinomas
    • Masaki T., Matsuoka H., Sugiyama M., Abe N., Sakamoto A., Atomi Y. Actual number of tumor budding as a new tool for the individualization of treatment of T1 colorectal carcinomas. J Gastroenterol Hepatol 2006 Jul, 21:1115-1121.
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 1115-1121
    • Masaki, T.1    Matsuoka, H.2    Sugiyama, M.3    Abe, N.4    Sakamoto, A.5    Atomi, Y.6
  • 54
    • 0346780671 scopus 로고    scopus 로고
    • Predictive factors for lymph node metastasis in T1 stage colorectal carcinomas
    • Sakuragi M., Togashi K., Konishi F., et al. Predictive factors for lymph node metastasis in T1 stage colorectal carcinomas. Dis Colon Rectum 2003 Dec, 46:1626-1632.
    • (2003) Dis Colon Rectum , vol.46 , pp. 1626-1632
    • Sakuragi, M.1    Togashi, K.2    Konishi, F.3
  • 55
    • 29744465560 scopus 로고    scopus 로고
    • Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified
    • Ward R.L., Turner J., Williams R., et al. Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified. J Pathol 2005 Dec, 207:377-384.
    • (2005) J Pathol , vol.207 , pp. 377-384
    • Ward, R.L.1    Turner, J.2    Williams, R.3
  • 56
    • 79953856354 scopus 로고    scopus 로고
    • Value of mismatch repair, KRAS, and BRAF mutations in predicting recurrence and benefits from chemotherapy in colorectal cancer
    • A 1
    • Hutchins G., Southward K., Handley K., et al. Value of mismatch repair, KRAS, and BRAF mutations in predicting recurrence and benefits from chemotherapy in colorectal cancer. J Clin Oncol 2011 Apr 1, 29:1261-1270.
    • (2011) J Clin Oncol , vol.29 , pp. 1261-1270
    • Hutchins, G.1    Southward, K.2    Handley, K.3
  • 57
    • 77954748953 scopus 로고    scopus 로고
    • Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer
    • J 10
    • Sargent D.J., Marsoni S., Monges G., et al. Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer. J Clin Oncol 2010 Jul 10, 28:3219-3226.
    • (2010) J Clin Oncol , vol.28 , pp. 3219-3226
    • Sargent, D.J.1    Marsoni, S.2    Monges, G.3
  • 58
    • 75749102647 scopus 로고    scopus 로고
    • Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial
    • J 20
    • Roth A.D., Tejpar S., Delorenzi M., et al. Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial. J Clin Oncol 2010 Jan 20, 28:466-474.
    • (2010) J Clin Oncol , vol.28 , pp. 466-474
    • Roth, A.D.1    Tejpar, S.2    Delorenzi, M.3
  • 59
    • 64049090889 scopus 로고    scopus 로고
    • Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR
    • Heinemann V., Stintzing S., Kirchner T., Boeck S., Jung A. Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR. Cancer Treat Rev 2009 May, 35:262-271.
    • (2009) Cancer Treat Rev , vol.35 , pp. 262-271
    • Heinemann, V.1    Stintzing, S.2    Kirchner, T.3    Boeck, S.4    Jung, A.5
  • 60
    • 40749120502 scopus 로고    scopus 로고
    • Identification of patients with (atypical) MUTYH-associated polyposis by KRAS2 c.34G > T prescreening followed by MUTYH hotspot analysis in formalin-fixed paraffin-embedded tissue
    • J 1
    • van Puijenbroek M., Nielsen M., Tops C.M., et al. Identification of patients with (atypical) MUTYH-associated polyposis by KRAS2 c.34G > T prescreening followed by MUTYH hotspot analysis in formalin-fixed paraffin-embedded tissue. Clin Cancer Res 2008 Jan 1, 14:139-142.
    • (2008) Clin Cancer Res , vol.14 , pp. 139-142
    • van Puijenbroek, M.1    Nielsen, M.2    Tops, C.M.3
  • 61
    • 73349091211 scopus 로고    scopus 로고
    • Biomarkers of resistance to epidermal growth factor receptor monoclonal antibodies in patients with metastatic colorectal cancer
    • D 15
    • Banck M.S., Grothey A. Biomarkers of resistance to epidermal growth factor receptor monoclonal antibodies in patients with metastatic colorectal cancer. Clin Cancer Res 2009 Dec 15, 15:7492-7501.
    • (2009) Clin Cancer Res , vol.15 , pp. 7492-7501
    • Banck, M.S.1    Grothey, A.2
  • 62
    • 79952282994 scopus 로고    scopus 로고
    • BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer
    • M 1
    • Yokota T., Ura T., Shibata N., et al. BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer. Br J Cancer 2011 Mar 1, 104:856-862.
    • (2011) Br J Cancer , vol.104 , pp. 856-862
    • Yokota, T.1    Ura, T.2    Shibata, N.3
  • 63
    • 79958817037 scopus 로고    scopus 로고
    • Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer
    • epub ahead of print
    • Tran B., Kopetz S., Tie J., et al. Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer. Cancer 2011, epub ahead of print.
    • (2011) Cancer
    • Tran, B.1    Kopetz, S.2    Tie, J.3
  • 64
    • 35348908314 scopus 로고    scopus 로고
    • PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients
    • O 22
    • Frattini M., Saletti P., Romagnani E., et al. PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients. Br J Cancer 2007 Oct 22, 97:1139-1145.
    • (2007) Br J Cancer , vol.97 , pp. 1139-1145
    • Frattini, M.1    Saletti, P.2    Romagnani, E.3
  • 65
    • 59049089201 scopus 로고    scopus 로고
    • PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients
    • Perrone F., Lampis A., Orsenigo M., et al. PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients. Ann Oncol 2009 Jan, 20:84-90.
    • (2009) Ann Oncol , vol.20 , pp. 84-90
    • Perrone, F.1    Lampis, A.2    Orsenigo, M.3
  • 66
    • 78049443211 scopus 로고    scopus 로고
    • Relationship between colorectal cancer biomarkers and response to epidermal growth factor receptor monoclonal antibodies
    • author reply e32-e33, O 1
    • Hawkes E., Cunningham D. Relationship between colorectal cancer biomarkers and response to epidermal growth factor receptor monoclonal antibodies. J Clin Oncol 2010 Oct 1, 28:e529-e531. author reply e32-e33.
    • (2010) J Clin Oncol , vol.28
    • Hawkes, E.1    Cunningham, D.2
  • 67
    • 77949435827 scopus 로고    scopus 로고
    • Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer
    • M 1
    • Bardelli A., Siena S. Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer. J Clin Oncol 2010 Mar 1, 28:1254-1261.
    • (2010) J Clin Oncol , vol.28 , pp. 1254-1261
    • Bardelli, A.1    Siena, S.2
  • 68
    • 63049111794 scopus 로고    scopus 로고
    • PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer
    • M 20
    • Ogino S., Nosho K., Kirkner G.J., et al. PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer. J Clin Oncol 2009 Mar 20, 27:1477-1484.
    • (2009) J Clin Oncol , vol.27 , pp. 1477-1484
    • Ogino, S.1    Nosho, K.2    Kirkner, G.J.3
  • 69
    • 62449302407 scopus 로고    scopus 로고
    • PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies
    • M 1
    • Sartore-Bianchi A., Martini M., Molinari F., et al. PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies. Cancer Res 2009 Mar 1, 69:1851-1857.
    • (2009) Cancer Res , vol.69 , pp. 1851-1857
    • Sartore-Bianchi, A.1    Martini, M.2    Molinari, F.3
  • 70
    • 65649086786 scopus 로고    scopus 로고
    • PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer
    • M 1
    • Prenen H., De Schutter J., Jacobs B., et al. PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer. Clin Cancer Res 2009 May 1, 15:3184-3188.
    • (2009) Clin Cancer Res , vol.15 , pp. 3184-3188
    • Prenen, H.1    De Schutter, J.2    Jacobs, B.3
  • 71
    • 79951506562 scopus 로고    scopus 로고
    • Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer
    • J 1
    • Salazar R., Roepman P., Capella G., et al. Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer. J Clin Oncol 2011 Jan 1, 29:17-24.
    • (2011) J Clin Oncol , vol.29 , pp. 17-24
    • Salazar, R.1    Roepman, P.2    Capella, G.3


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