In vitro evaluation of the effects of intraluminal thrombus on abdominal aortic aneurysm wall dynamics

Medical Engineering and Physics

Volumn 33, Issue 8, 2011, Pages 957-966

  Ene, Florentina ^a   Gachon, Carine ^a   Delassus, Patrick ^a   Carroll, Ronan ^a   Stefanov, Florian ^a   O'Flynn, Padraig ^a   Morris, Liam ^a  

^a Atlantic Technological University   (Ireland)

Author keywords

Abdominal aortic aneurysm; Compliance; Diametral strain; Intraluminal thrombus; Silicone models

Indexed keywords

ABDOMINAL AORTIC ANEURYSMS; COMPLIANCE; DIAMETRAL STRAIN; ELASTIC STIFFNESS; IN-VITRO; IN-VITRO EVALUATION; INTRALUMINAL; PHYSIOLOGICAL CONDITION;

PHYSIOLOGICAL MODELS; SILICONES; STIFFNESS;

BLOOD VESSELS;

SILASTIC;

ABDOMINAL AORTA ANEURYSM; ANEURYSM RUPTURE; AORTA BIFURCATION; AORTA PRESSURE; AORTA WALL; ARTERY COMPLIANCE; ARTICLE; BIOMECHANICS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; EVALUATION; HYSTERESIS; IN VITRO STUDY; INTRALUMINAL THROMBUS; NONBIOLOGICAL MODEL; PRIORITY JOURNAL; SILASTIC TUBE; SYSTOLIC BLOOD PRESSURE; THROMBUS; THROMBUS STIFFNESS; WAVEFORM; YOUNG MODULUS;

AORTA, ABDOMINAL; AORTIC ANEURYSM, ABDOMINAL; HUMANS; MALE; MODELS, ANATOMIC; NORMAL DISTRIBUTION; PRESSURE; REPRODUCIBILITY OF RESULTS; STRESS, MECHANICAL; THROMBOSIS;

EID: 80051818989     PISSN: 13504533     EISSN: 18734030     Source Type: Journal    
DOI: 10.1016/j.medengphy.2011.03.005     Document Type: Article

References (47)

1. National Center for Injury Prevention and Control WISQARS leading causes of death reports 1999-2007, [accessed 01.12.10].
2. World Heatlh Organisation World health statistics 2006, World Health Organisation, [accessed May 2010].
3. Harter L.P., Gross B.H., Callen P.W., Barth R.A. Ultrasonic evaluation of abdominal aortic thrombus. Journal of Ultrasound in Medicine 1982, 1(October (8)):315-318.
4. Wang D.H., Makaroun M., Webster M.W., Vorp D.A. Mechanical properties and microstructure of intraluminal thrombus from abdominal aortic aneurysm. Journal of Biomechanical Engineering 2001, 123(December (6)):536-539.
5. Satta J., Laara E., Juvonen T. Intraluminal thrombus predicts rupture of an abdominal aortic aneurysm. Journal of Vascular Surgery 1996, 23(April (4)):737-739.
6. Vorp D.A., Mandarino W.A., Webster M.W., Gorcsan J. Potential influence of intraluminal thrombus on abdominal aortic aneurysm as assessed by a new non-invasive method. Cardiovascular Surgery 1996, 4(6):732-739.
7. Wang D.H., Makaroun M.S., Webster M.W., Vorp D.A. Effect of intraluminal thrombus on wall stress in patient-specific models of abdominal aortic aneurysm. Journal of Vascular Surgery 2002, 36(September (3)):598-604.
8. Di Martino E., Mantero S., Inzoli F., Melissano G., Astore D., Chiesa R., et al. Biomechanics of abdominal aortic aneurysm in the presence of endoluminal thrombus: experimental characterisation and structural static computational analysis. European Journal of Vascular and Endovascular Surgery 1998, 15(4):290-299.
9. Di Martino E.S., Vorp D.A. Effect of variation in intraluminal thrombus constitutive properties on abdominal aortic aneurysm wall stress. Annals of Biomedical Engineering 2003, 31(July-August (7)):804-809.
10. Inzoli F., Boschetti F., Zappa M., Longo T., Fumero R. Biomechanical factors in abdominal aortic aneurysm rupture. European Journal of Vascular Surgery 1993, 7(November (6)):667-674.
11. Li Z.Y., U.K.-I J., Tang T.Y., Soh E., See T.C, Gillard.J.H. Impact of calcification and intraluminal thrombus on the computed wall stresses of abdominal aortic aneurysm. Journal of Vascular Surgery 2008, 47(May (5)):928-935.
12. Mower W.R., Quiñones W.J., Gambhir S.S. Effect of intraluminal thrombus on abdominal aortic aneurysm wall stress. Journal of Vascular Surgery 1997, 26(4):602-608.
13. Chaudhuri A., Ansdell L.E., Grass A.J., Adiseshiah M. Intrasac pressure waveforms after endovascular aneurysm repair (EVAR) are a reliable marker of type I endoleaks, but not type II or combined types: an experimental study. European Journal of Vascular and Endovascular Surgery 2004, 28(October (4)):373-378.
14. Deplano V., Knapp Y., Bertrand E., Gaillard E. Flow behaviour in an asymmetric compliant experimental model for abdominal aortic aneurysm. Journal of Biomechanics 2007, 40(11):2406-2413.
15. Flora H.S., Talei-Faz B., Ansdell L., Chaloner E.J., Sweeny A., Grass A., et al. Aneurysm wall stress and tendency to rupture are features of physical wall properties: an experimental study. Journal of Endovascular Therapy 2002, 9(5):665-675.
16. Morris L.G. Numerical and experimental investigation of mechanical factors in the treatment of abdominal aortic aneurysms 2004, University of Limerick, Limerick, p. 211.
17. O'Flynn P.M., Roche E.T., Pandit A.S. Generating an ex vivo vascular model. Asaio Journal 2005, 51(July-August (4)):426-433.
18. Chaudhuri A., Ansdell L.E., Richards R., Adiseshiah M., Grass A.J. Non-axisymmetrical (life-like) abdominal aortic aneurysm models: a do-it-yourself approach. Journal of Endovascular Therapy 2003, (December (6)):1097-1100.
19. Chueh J.Y., Wakhloo A.K., Gounis M.J. Neurovascular modeling: small-batch manufacturing of silicone vascular replicas. AJNR American Journal of Neuroradiology 2009, (June (6)):1159-1164.
20. Doyle B.J., Corbett T.J., Cloonan A.J., O'Donnell M.R., Walsh M.T., Vorp D.A., et al. Experimental modelling of aortic aneurysms: novel applications of silicone rubbers. Medical Engineering & Physics 2009, 31(8):1002-1012.
21. Hinnen J.W., Rixen D.J., Koning O.H., van Bockel J.H., Hamming J.F. Development of fibrinous thrombus analogue for in-vitro abdominal aortic aneurysm studies. Journal of Biomechanics 2007, 40(2):289-295.
22. O'Brien T., Morris L., O'Donnell M., Walsh M., McGloughlin T. Injection-moulded models of major and minor arteries: the variability of model wall thickness owing to casting technique. Proceedings of the Institution of Mechanical Engineers 2005, 219(September (5)):381-386.
23. Hinnen J.W., Koning O.H., Visser M.J., Van Bockel H.J. Effect of intraluminal thrombus on pressure transmission in the abdominal aortic aneurysm. Journal of Vascular Surgery 2005, 42(December (6)):1176-1182.
24. Doyle B.J., Morris L.G., Callanan A., Kelly P., Vorp D.A., McGloughlin T.M. 3D reconstruction and manufacture of real abdominal aortic aneurysms: from CT 480 scan to silicone model. Journal of Biomechanical Engineering 2008, 130(Jun (3)):034501.
25. Timaran C.H., Ohki T., Veith F.J., Lipsitz E.C., Gargiulo N.J., Rhee S.J., et al. Influence of type II endoleak volume on aneurysm wall pressure and distribution in an experimental model. Journal of Vascular Surgery 2005, 41(4):657-663.
26. Gasser T.C., Gorgulu G., Folkesson M., Swedenborg J. Failure properties of intraluminal thrombus in abdominal aortic aneurysm under static and pulsating mechanical loads. Journal of Vascular Surgery 2008, 48(July (1)):179-188.
27. Li Z., Kleinstreuer C. Blood flow and structure interactions in a stented abdominal aortic aneurysm model. Medical Engineering & Physics 2005, 27(5):369-382.
28. Klabunde R.E. Cardiovascular Physiology Concepts 2005, Williams & Wilkins, Lippincott.
29. Raghavan M.L., Vorp D.A. Toward a biomechanical tool to evaluate rupture potential of abdominal aortic aneurysm: identification of a finite strain constitutive model and evaluation of its applicability. Journal of Biomechanics 2000, 33(April (4)):475-482.
30. Sonesson B., Lanne T., Vernersson E., Hansen F. Sex difference in the mechanical properties of the abdominal aorta in human beings. Journal of Vascular Surgery 1994, 20(December (6)):959-969.
31. Kushihashi T., Munechika H., Matsui S., Moritani T., Horichi Y., Hishida T. CT of abdominal aortic aneurysms-aneurysmal size and thickness of intra-aneurysmal thrombus as risk factors of rupture. Nihon Igaku Hoshasen Gakkai zasshi 1991, 51(March (3)):219-227.
32. Pillari G., Chang J.B., Zito J., Cohen J.R., Gersten K., Rizzo A., et al. Computed tomography of abdominal aortic aneurysm. An in vivo pathological report with a note on dynamic predictors. Archives of Surgery 1988, 123(6):727-732.
33. Thubrikar M.J., Robicsek F., Labrosse M., Chervenkoff V., Fowler B.L. Effect of thrombus on abdominal aortic aneurysm wall dilation and stress. Journal of Cardiovascular Surgery 2003, 44(February (1)):67-77.
34. Fillinger M.F., Marra S.P., Raghavan M.L., Kennedy F.E. Prediction of rupture risk in abdominal aortic aneurysm during observation: wall stress versus diameter. Journal of Vascular Surgery 2003, 37(4):724-732.
35. Morris L., O'Donnell P., Delassus P., McGloughlin T. Experimental assessment of stress patterns in abdominal aortic aneurysms using the photoelastic method. Strain 2004, 40(4):165-172.
36. Raghavan M.L., Vorp D.A., Federle M.P., Makaroun M.S., Webster M.W. Wall stress distribution on three-dimensionally reconstructed models of human abdominal aortic aneurysm. Journal of Vascular Surgery 2000, 31(4):760-769.
37. Sacks M.S., Vorp D.A., Raghavan M.L., Federle M.P., Webster M.W. In vivo three-dimensional surface geometry of abdominal aortic aneurysms. Annals of Biomedical Engineering 1999, 27(4):469-479.
38. Schurink G.W.H., Baalen JMv, Visser M.J.T., Bockel JHv. Thrombus within an aortic aneurysm does not reduce pressure on the aneurysmal wall. Journal of Vascular Surgery: Official Publication, The Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 2000, 31(3):501-506.
39. Hans S.S., Jareunpoon O., Huang R., Hans B., Bove P., Zelenock G.B. Relationship of residual intraluminal to intrathrombotic pressure in a closed aneurysmal sac. Journal of Vascular Surgery: Official Publication, The Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 2003, 37(5):949-953.
40. Vorp D.A., Lee P.C., Wang D.H., Makaroun M.S., Nemoto E.M., Ogawa S., et al. Association of intraluminal thrombus in abdominal aortic aneurysm with local hypoxia and wall weakening. Journal of Vascular Surgery 2001, 34(2):291-299.
41. Gasser T.C., Auer M., Labruto F., Swedenborg J., Roy J. Biomechanical Rupture Risk Assessment of Abdominal Aortic Aneurysms: Model Complexity versus Predictability of Finite Element Simulations. European Journal of Vascular and Endovascular Surgery 2010, 40(2):176-185.
42. Raghavan M.L., Kratzberg J., Castro de Tolosa E.M., Hanaoka M.M., Walker P., da Silva E.S. Regional distribution of wall thickness and failure properties of human abdominal aortic aneurysm. Journal of Biomechanics 2006, 39(16):3010-3016.
43. Gasser T.C., Martufi G., Auer M., Folkesson M., Swedenborg J. Micromechanical characterization of intra-luminal thrombus tissue from abdominal aortic aneurysms. Annals of Biomedical Engineering 2009 November 17.
44. Kazi M., Thyberg J., Religa P., Roy J., Eriksson P., Hedin U., et al. Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall. Journal of Vascular Surgery 2003, 38(6):1283-1292.
45. Roy J., Labruto F., Beckman M.O., Danielson J., Johansson G., Swedenborg J. Bleeding into the intraluminal thrombus in abdominal aortic aneurysms is associated with rupture. Journal of Vascular Surgery 2008, 48(november (5)):1108-1113.
46. Pacanowski J.P., Stevens S.L., Freeman M.B., Dieter R.S., Klosterman L.A., Kirkpatrick S.S., et al. Endotension distribution and the role of thrombus following endovascular AAA exclusion. Journal of Endovascular Therapy 2002, 9(5):639-651.
47. Corbett TJ, Doyle BJ, Callanan A, Walsh MT, McGloughlin TM., Engineering silicone rubbers for in vitro studies: creating AAA models and ILT analogues with physiological properties. Journal of Biomechanical Engineering 2010; 132(1):011008.