Circulating insulin stimulates fatty acid retention in white adipose tissue via K ATP channel activation in the central nervous System only in insulin-sensitive mice

Journal of Lipid Research

Volumn 52, Issue 9, 2011, Pages 1712-1722

  Coomans, Claudia P ^a   Geerling, Janine J ^a   Guigas, Bruno ^a   Van Den Hoek, Anita M ^a,b   Parlevliet, Edwin T ^a   Ouwens, D Margriet ^a,d   Pijl, Hanno ^a   Voshol, Peter J ^a,e   Rensen, Patrick C N ^a   Havekes, Louis M ^a,b   Romijn, Johannes A ^a,c  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b TNO   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Brain; Brown adipose tissue; Insulin resistance; Lipid metabolism; Lipoprotein lipase; Triglycerides

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CD36 ANTIGEN; CYCLIC AMP; FATTY ACID; INSULIN; LEPTIN; SERUM ALBUMIN; TOLBUTAMIDE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CENTRAL NERVOUS SYSTEM; CHANNEL GATING; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG TARGETING; FATTY ACID METABOLISM; FATTY ACID RETENTION; HORMONE ACTION; HYPERINSULINEMIA; INSULIN ACTION; INSULIN SENSITIVITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WHITE ADIPOSE TISSUE; WILD TYPE;

ADIPOSE TISSUE, BROWN; ADIPOSE TISSUE, WHITE; ANIMALS; ANTIGENS, CD36; CENTRAL NERVOUS SYSTEM; DIET; FATTY ACIDS; INSULIN; KATP CHANNELS; MALE; MICE; MICE, INBRED C57BL; OBESITY; SIGNAL TRANSDUCTION;

EID: 80051810499     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M015396     Document Type: Article

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