Serum soluble E-selectin and NT-proBNP levels additively predict mortality in diabetic patients with chronic heart failure

Clinical Research in Cardiology

Volumn 100, Issue 7, 2011, Pages 587-594

  Czúcz, Judit ^a   Cervenak, László ^b   Förhécz, Zsolt ^a   Gombos, Tímea ^a   Pozsonyi, Zoltán ^a   Kunde, Jan ^c   Karádi, István ^a   Jánoskuti, Lívia ^a   Prohászka, Zoltán ^b  

^a SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c THERMO FISHER SCIENTIFIC   (Germany)

Author keywords

Heart failure; Inflammation; NT proBNP; SE selectin

Indexed keywords

ACETYLSALICYLIC ACID; AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; C REACTIVE PROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 6; LOOP DIURETIC AGENT; SOLUBLE ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; DIABETES MELLITUS; DIABETIC PATIENT; DIASTOLIC BLOOD PRESSURE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; POPULATION; PREDICTION; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; SURVIVOR; SYSTOLIC BLOOD PRESSURE; SYSTOLIC HEART FAILURE;

AGED; CHRONIC DISEASE; COHORT STUDIES; CYTOKINES; DIABETES COMPLICATIONS; E-SELECTIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HEART FAILURE; HUMANS; MALE; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; PEPTIDE FRAGMENTS; PROGNOSIS; PROSPECTIVE STUDIES;

EID: 80051803006     PISSN: 18610684     EISSN: 18610692     Source Type: Journal    
DOI: 10.1007/s00392-011-0283-6     Document Type: Article

References (24)

1. Anker SD, von Haehling S (2004) Inflammatory mediators in chronic heart failure: an overview. Heart 90:464-470 (Pubitemid 38406929)
2. Devaux B, Scholz D, Hirche A, Klövekorn WP, Schaper J (1997) Upregulation of cell adhesion molecules and the presence of low grade inflammation in human chronic heart failure. Eur Heart J 18:470-479 (Pubitemid 27110479)
3. Chong AY, Blann AD, Patel J, Freestone B, Hughes E, Lip GYH (2004) Endothelial dysfunction and damage in congestive heart failure: relation of flow-mediated dilation to circulating endothelial cells, plasma indexes of endothelial damage, and brain natriuretic peptide. Circulation 110:1794-1798 (Pubitemid 39302656)
4. Gombos T, Makó V, Cervenak L, Papassotiriou J, Kunde J, Hársfalvi J, Förhécz Z, Pozsonyi Z, Borgulya G et al (2009) Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure. Thromb Haemost 102:573-580
5. Khan SQ, Dhillon O, Struck J, Quinn P, Morgenthaler NG, Squire IB, Davies JE, Bergmann A, Ng LL (2007) C-terminal proendothelin-1 offers additional prognostic information in patients after acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) Study. Am Heart J 154:736-742 (Pubitemid 47429589)
6. Chong A-Y, Blann AD, Lip GYH (2003) Assessment of endothelial damage and dysfunction: observations in relation to heart failure. QJM 96:253-267 (Pubitemid 36432385)
7. Chong AY, Lip GYH, Freestone B, Blann AD (2006) Increased circulating endothelial cells in acute heart failure: comparison with von Willebrand factor and soluble E-selectin. Eur J Heart Fail 8:167-172 (Pubitemid 43240851)
8. Roldán V, Marín F, Lip GYH, Blann AD (2003) Soluble E-selectin in cardiovascular disease and its risk factors. A review of the literature. Thromb Haemost 90:1007-1020 (Pubitemid 38004418)
9. Pigott R, Dillon LP, Hemingway IH, Gearing AJ (1992) Soluble forms of E-selectin, ICAM-1 and VCAM-1 are present in the supernatants of cytokine activated cultured endothelial cells. Biochem Biophys Res Commun 187:584-589
10. Andreassen AK, Nordøy I, Simonsen S, Ueland T, Müller F, Frøland SS, Gullestad L, Aukrust P (1998) Levels of circulating adhesion molecules in congestive heart failure and after heart transplantation. Am J Cardiol 81:604-608 (Pubitemid 28182426)
11. Potapov EV, Hennig F, Wagner FD, Volk H-D, Sodian R, Hausmann H, Lehmkuhl HB, Hetzer R (2005) Natriuretic peptides and E-selectin as predictors of acute deterioration in patients with inotrope-dependent heart failure. Eur J Cardiothorac Surg 27:899-905 (Pubitemid 40585688)
12. Chong AY, Freestone B, Lim HS, Kistorp C, Gustafsson F, Hildebrandt P, Lip GYH (2007) Plasma von Willebrand factor and soluble E-selectin levels in stable outpatients with systolic heart failure: the Frederiksberg heart failure study. Int J Cardiol 119:80-82 (Pubitemid 46818475)
13. White M, Ducharme A, Ibrahim R, Whittom L, Lavoie J, Guertin M-C, Racine N, He Y, Yao G et al (2006) Increased systemic inflammation and oxidative stress in patients with worsening congestive heart failure: improvement after short-term inotropic support. Clin Sci 110:483-489
14. Kistorp C, Chong AY, Gustafsson F, Galatius S, Raymond I, Faber J, Lip GYH, Hildebrandt P (2008) Biomarkers of endothelial dysfunction are elevated and related to prognosis in chronic heart failure patients with diabetes but not in those without diabetes. Eur J Heart Fail 10:380-387
15. Chong AY, Freestone B, Patel J, Lim HS, Hughes E, Blann AD, Lip GYH (2006) Endothelial activation, dysfunction, and damage in congestive heart failure and the relation to brain natriuretic peptide and outcomes. Am J Cardiol 97:671-675 (Pubitemid 43255037)
16. Förhécz Z, Gombos T, Borgulya G, Pozsonyi Z, Prohászka Z, Jánoskuti L (2009) Red cell distribution width in heart failure: prediction of clinical events and relationship with markers of ineffective erythropoiesis, inflammation, renal function, and nutritional state. Am Heart J 158:659-666
17. Gombos T, Förhécz Z, Pozsonyi Z, Wallentin S, Papassotiriou J, Kunde J, Morgenthaler NG, Jánoskuti L, Prohászka Z (2009) Adrenomedullin and endothelin-1 are related to inflammation in chronic heart failure. Inflamm Res 58:298-305
18. Leeuwenberg JF, Smeets EF, Neefjes JJ, Shaffer MA, Cinek T, Jeunhomme TM, Ahern TJ, Buurman WA (1992) E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro. Immunology 77:543-549 (Pubitemid 23000475)
19. Blann AD (2000) Endothelial cell activation, injury, damage and dysfunction: separate entities or mutual terms? Blood Coagul Fibrinolysis 11:623-630
20. Levine B, Kalman J, Mayer L, Fillit HM, Packer M (1990) Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med 323:236-241 (Pubitemid 20225044)
21. Sharma R, Coats AJ, Anker SD (2000) The role of inflammatory mediators in chronic heart failure: cytokines, nitric oxide, and endothelin-1. Int J Cardiol 72:175-186 (Pubitemid 30068636)
22. Suzuki T, Katz R, Jenny NS, Zakai NA, LeWinter MM, Barzilay JI, Cushman M (2008) Metabolic syndrome, inflammation, and incident heart failure in the elderly: the cardiovascular health study. Circ Heart Fail 1:242-248
23. Kaplanski G, Farnarier C, Benoliel AM, Foa C, Kaplanski S, Bongrand P (1994) A novel role for E- and P-selectins: shape control of endothelial cell monolayers. J Cell Sci 107:2449-2457 (Pubitemid 24292493)
24. Emdin M, Vittorini S, Passino C, Clerico A (2009) Old and new biomarkers of heart failure. Eur J Heart Fail 11:331-335