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Volumn 8, Issue , 2011, Pages

Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB1 receptors

Author keywords

Blood brain barrier; Endocannabinoids; Multiple Sclerosis; TMEV; VCAM 1

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; ANANDAMIDE; CANNABINOID 1 RECEPTOR; CAPSAZEPINE; N (3 FURYLMETHYL)ARACHIDONAMIDE; RIMONABANT; VASCULAR CELL ADHESION MOLECULE 1; AMIDE; ARACHIDONIC ACID DERIVATIVE; ENDOCANNABINOID;

EID: 80051802511     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-8-102     Document Type: Article
Times cited : (58)

References (64)
  • 1
    • 23744475685 scopus 로고    scopus 로고
    • The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms
    • 10.1016/j.it.2005.07.004, 16039904
    • Engelhardt B, Ransohoff RM. The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms. Trends Immunol 2005, 26:485-495. 10.1016/j.it.2005.07.004, 16039904.
    • (2005) Trends Immunol , vol.26 , pp. 485-495
    • Engelhardt, B.1    Ransohoff, R.M.2
  • 2
    • 78651063705 scopus 로고    scopus 로고
    • Leucocyte-endothelial cell crosstalk at the blood-brain barrier: A prerequisite for successful immune cell entry to the brain
    • 10.1111/j.1365-2990.2010.01140.x, 20946472
    • Greenwood J, Heasman SJ, Alvarez JI, Prat A, Lyck R, Engelhardt B. Leucocyte-endothelial cell crosstalk at the blood-brain barrier: A prerequisite for successful immune cell entry to the brain. Neuropathol Appl Neurobiol 2011, 37:24-39. 10.1111/j.1365-2990.2010.01140.x, 20946472.
    • (2011) Neuropathol Appl Neurobiol , vol.37 , pp. 24-39
    • Greenwood, J.1    Heasman, S.J.2    Alvarez, J.I.3    Prat, A.4    Lyck, R.5    Engelhardt, B.6
  • 3
    • 34447560029 scopus 로고    scopus 로고
    • Cell surface adhesion molecules and cytokine profiles in primary progressive multiple sclerosis
    • 10.1177/1352458506075378, 17613596
    • Ukkonen M, Wu K, Reipert B, Dastidar P, Elovaara I. Cell surface adhesion molecules and cytokine profiles in primary progressive multiple sclerosis. Mult Scler 2007, 13:701-707. 10.1177/1352458506075378, 17613596.
    • (2007) Mult Scler , vol.13 , pp. 701-707
    • Ukkonen, M.1    Wu, K.2    Reipert, B.3    Dastidar, P.4    Elovaara, I.5
  • 4
    • 0029319566 scopus 로고
    • Cytokine localization in multiple sclerosis lesions: correlation with adhesion molecule expression and reactive nitrogen species
    • Brosnan CF, Cannella B, Battistini L, Raine CS. Cytokine localization in multiple sclerosis lesions: correlation with adhesion molecule expression and reactive nitrogen species. Neurology 1995, 45:S16-S21.
    • (1995) Neurology , vol.45
    • Brosnan, C.F.1    Cannella, B.2    Battistini, L.3    Raine, C.S.4
  • 5
    • 0026506799 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin
    • 10.1038/356063a0, 1538783
    • Yednock TA, Cannon C, Fritz LC, Sanchez-Madrid F, Steinman L, Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature 1992, 356:63-66. 10.1038/356063a0, 1538783.
    • (1992) Nature , vol.356 , pp. 63-66
    • Yednock, T.A.1    Cannon, C.2    Fritz, L.C.3    Sanchez-Madrid, F.4    Steinman, L.5    Karin, N.6
  • 8
    • 0017085526 scopus 로고
    • Chronic neurologic disease in Theiler's virus infection of SJL/J mice
    • 10.1016/0022-510X(76)90267-7, 978224
    • Lipton HL, Dal Canto MC. Chronic neurologic disease in Theiler's virus infection of SJL/J mice. J Neurol Sci 1976, 30:201-207. 10.1016/0022-510X(76)90267-7, 978224.
    • (1976) J Neurol Sci , vol.30 , pp. 201-207
    • Lipton, H.L.1    Dal Canto, M.C.2
  • 9
    • 78049232267 scopus 로고    scopus 로고
    • Intracellular trafficking of anandamide: new concepts for signaling
    • 10.1016/j.tibs.2010.05.008, 20570522
    • Maccarrone M, Dainese E, Oddi S. Intracellular trafficking of anandamide: new concepts for signaling. Trends Biochem Sci 2010, 35:601-608. 10.1016/j.tibs.2010.05.008, 20570522.
    • (2010) Trends Biochem Sci , vol.35 , pp. 601-608
    • Maccarrone, M.1    Dainese, E.2    Oddi, S.3
  • 10
    • 77952651099 scopus 로고    scopus 로고
    • The endocannabinoid system as a target for the treatment of neurodegenerative disease
    • 10.1111/j.1476-5381.2010.00735.x, 2931550, 20590559
    • Scotter EL, Abood ME, Glass M. The endocannabinoid system as a target for the treatment of neurodegenerative disease. Br J Pharmacol 2010, 160:480-498. 10.1111/j.1476-5381.2010.00735.x, 2931550, 20590559.
    • (2010) Br J Pharmacol , vol.160 , pp. 480-498
    • Scotter, E.L.1    Abood, M.E.2    Glass, M.3
  • 11
    • 77953695557 scopus 로고    scopus 로고
    • The endocannabinoid system in the inflammatory and neurodegenerative processes of multiple sclerosis and of amyotrophic lateral sclerosis
    • 10.1016/j.expneurol.2010.03.030, 20353778
    • Rossi S, Bernardi G, Centonze D. The endocannabinoid system in the inflammatory and neurodegenerative processes of multiple sclerosis and of amyotrophic lateral sclerosis. Exp Neurol 2010, 224:92-102. 10.1016/j.expneurol.2010.03.030, 20353778.
    • (2010) Exp Neurol , vol.224 , pp. 92-102
    • Rossi, S.1    Bernardi, G.2    Centonze, D.3
  • 14
    • 33646142292 scopus 로고    scopus 로고
    • The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines
    • 10.1016/j.nbd.2005.11.004, 16364651
    • Panikashvili D, Shein NA, Mechoulam R, Trembovler V, Kohen R, Alexandrovich A, Shohami E. The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines. Neurobiol Dis 2006, 22:257-264. 10.1016/j.nbd.2005.11.004, 16364651.
    • (2006) Neurobiol Dis , vol.22 , pp. 257-264
    • Panikashvili, D.1    Shein, N.A.2    Mechoulam, R.3    Trembovler, V.4    Kohen, R.5    Alexandrovich, A.6    Shohami, E.7
  • 16
    • 77953712552 scopus 로고    scopus 로고
    • Modulation of the endocannabinoid system: neuroprotection or neurotoxicity?
    • 10.1016/j.expneurol.2010.03.021, 20353772
    • Fowler CJ, Rojo ML, Rodriguez-Gaztelumendi A. Modulation of the endocannabinoid system: neuroprotection or neurotoxicity?. Exp Neurol 2010, 224:37-47. 10.1016/j.expneurol.2010.03.021, 20353772.
    • (2010) Exp Neurol , vol.224 , pp. 37-47
    • Fowler, C.J.1    Rojo, M.L.2    Rodriguez-Gaztelumendi, A.3
  • 17
    • 26944483132 scopus 로고    scopus 로고
    • Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis
    • 10.1016/j.nbd.2005.03.002, 16242629
    • Cabranes A, Venderova K, de Lago E, Fezza F, Sánchez A, Mestre L, Valenti M, García-Merino A, Ramos JA, Di Marzo V, Fernández-Ruiz J. Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis. Neurobiol Dis 2005, 20:207-217. 10.1016/j.nbd.2005.03.002, 16242629.
    • (2005) Neurobiol Dis , vol.20 , pp. 207-217
    • Cabranes, A.1    Venderova, K.2    de Lago, E.3    Fezza, F.4    Sánchez, A.5    Mestre, L.6    Valenti, M.7    García-Merino, A.8    Ramos, J.A.9    Di Marzo, V.10    Fernández-Ruiz, J.11
  • 19
    • 52949125632 scopus 로고    scopus 로고
    • The endocannabinoid system in peripheral lymphocytes as a mirror of neuroinflammatory diseases
    • 10.2174/138161208785740018, 18781987
    • Centonze D, Battistini L, Maccarrone M. The endocannabinoid system in peripheral lymphocytes as a mirror of neuroinflammatory diseases. Curr Pharm Des 2008, 14:2370-2342. 10.2174/138161208785740018, 18781987.
    • (2008) Curr Pharm Des , vol.14 , pp. 2370-12342
    • Centonze, D.1    Battistini, L.2    Maccarrone, M.3
  • 22
    • 0242654882 scopus 로고    scopus 로고
    • Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial
    • 10.1016/S0140-6736(03)14738-1, 14615106, UK MS Research Group
    • Zajicek J, Fox P, Sanders H, Wright D, Vickery J, Nunn A, Thompson A, . UK MS Research Group Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial. Lancet 2003, 362:1517-1526. 10.1016/S0140-6736(03)14738-1, 14615106, UK MS Research Group.
    • (2003) Lancet , vol.362 , pp. 1517-1526
    • Zajicek, J.1    Fox, P.2    Sanders, H.3    Wright, D.4    Vickery, J.5    Nunn, A.6    Thompson, A.7
  • 23
    • 16544377251 scopus 로고    scopus 로고
    • Win 55212-2, a cannabinoid receptor agonist, attenuates leukocyte/endothelial interactions in an experimental autoimmune encephalomyelitis model
    • 10.1191/1352458504ms1009oa, 15124761
    • Ni X, Geller EB, Eppihimer MJ, Eisenstein TK, Adler MW, Tuma RF. Win 55212-2, a cannabinoid receptor agonist, attenuates leukocyte/endothelial interactions in an experimental autoimmune encephalomyelitis model. Mult Scler 2004, 10:158-164. 10.1191/1352458504ms1009oa, 15124761.
    • (2004) Mult Scler , vol.10 , pp. 158-164
    • Ni, X.1    Geller, E.B.2    Eppihimer, M.J.3    Eisenstein, T.K.4    Adler, M.W.5    Tuma, R.F.6
  • 24
    • 59049099828 scopus 로고    scopus 로고
    • A cannabinoid agonist interferes with the progression of a chronic model of multiple sclerosis by downregulating adhesion molecules
    • 10.1016/j.mcn.2008.10.015, 19059482
    • Mestre L, Docagne F, Correa F, Loría F, Hernangómez M, Borrell J, Guaza C. A cannabinoid agonist interferes with the progression of a chronic model of multiple sclerosis by downregulating adhesion molecules. Mol Cell Neurosci 2009, 40:258-266. 10.1016/j.mcn.2008.10.015, 19059482.
    • (2009) Mol Cell Neurosci , vol.40 , pp. 258-266
    • Mestre, L.1    Docagne, F.2    Correa, F.3    Loría, F.4    Hernangómez, M.5    Borrell, J.6    Guaza, C.7
  • 25
    • 0032922060 scopus 로고    scopus 로고
    • Dexamethasone regulation of interleukin-1-receptors in the hippocampus of Theiler's virus-infected mice: effects on virus-mediated demyelination
    • 10.1016/S0014-2999(99)00187-9, 10374717
    • Lledó A, Borrell J, Guaza C. Dexamethasone regulation of interleukin-1-receptors in the hippocampus of Theiler's virus-infected mice: effects on virus-mediated demyelination. Eur J Pharmacol 1999, 372:75-83. 10.1016/S0014-2999(99)00187-9, 10374717.
    • (1999) Eur J Pharmacol , vol.372 , pp. 75-83
    • Lledó, A.1    Borrell, J.2    Guaza, C.3
  • 26
    • 0033622322 scopus 로고    scopus 로고
    • Interaction of alpha4-integrin with VCAM-1 is involved in adhesion of encephalitogenic T cell blasts to brain endothelium but not in their transendothelial migration in vitro
    • 10.1016/S0165-5728(99)00156-3, 10626664
    • Laschinger M, Engelhardt B. Interaction of alpha4-integrin with VCAM-1 is involved in adhesion of encephalitogenic T cell blasts to brain endothelium but not in their transendothelial migration in vitro. J Neuroimmunol 2000, 102:32-43. 10.1016/S0165-5728(99)00156-3, 10626664.
    • (2000) J Neuroimmunol , vol.102 , pp. 32-43
    • Laschinger, M.1    Engelhardt, B.2
  • 27
    • 0141894132 scopus 로고    scopus 로고
    • Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies
    • 10.1016/S0006-8993(03)03443-7, 14568334
    • Omidi Y, Campbell L, Barar J, Connell D, Akhtar S, Gumbleton M. Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies. Brain Res 2003, 990:95-112. 10.1016/S0006-8993(03)03443-7, 14568334.
    • (2003) Brain Res , vol.990 , pp. 95-112
    • Omidi, Y.1    Campbell, L.2    Barar, J.3    Connell, D.4    Akhtar, S.5    Gumbleton, M.6
  • 28
    • 38149139373 scopus 로고    scopus 로고
    • Evaluation of bEnd5 cell line as an in vitro model for the blood-brain barrier under normal and hypoxic/aglycemic conditions
    • 10.1002/jps.21002, 17828743
    • Yang T, Roder KE, Abbruscato TJ. Evaluation of bEnd5 cell line as an in vitro model for the blood-brain barrier under normal and hypoxic/aglycemic conditions. J Pharm Sci 2007, 96:3196-3213. 10.1002/jps.21002, 17828743.
    • (2007) J Pharm Sci , vol.96 , pp. 3196-3213
    • Yang, T.1    Roder, K.E.2    Abbruscato, T.J.3
  • 29
    • 0029382468 scopus 로고
    • Evidence for cyclooxygenase activation by nitric oxide in astrocytes
    • 10.1002/glia.440150209, 8567068
    • Molina-Holgado F, Lledó A, Guaza C. Evidence for cyclooxygenase activation by nitric oxide in astrocytes. Glia 1995, 15:167-172. 10.1002/glia.440150209, 8567068.
    • (1995) Glia , vol.15 , pp. 167-172
    • Molina-Holgado, F.1    Lledó, A.2    Guaza, C.3
  • 30
    • 0033673170 scopus 로고    scopus 로고
    • Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes
    • 10.1016/S0928-0987(00)00123-8, 11113640
    • Gaillard PJ, Voorwinden LH, Nielsen JL, Ivanov A, Atsumi R, Engman H, Ringbom C, de Boer AG, Breimer DD. Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes. Eur J Pharm Sci 2001, 12:215-222. 10.1016/S0928-0987(00)00123-8, 11113640.
    • (2001) Eur J Pharm Sci , vol.12 , pp. 215-222
    • Gaillard, P.J.1    Voorwinden, L.H.2    Nielsen, J.L.3    Ivanov, A.4    Atsumi, R.5    Engman, H.6    Ringbom, C.7    de Boer, A.G.8    Breimer, D.D.9
  • 31
    • 0037396482 scopus 로고    scopus 로고
    • Chemokine-dependent mechanisms of leukocyte trafficking across a model of the blood-brain barrier
    • 10.1016/S1046-2023(02)00359-6, 12725802
    • Eugenin EA, Berman JW. Chemokine-dependent mechanisms of leukocyte trafficking across a model of the blood-brain barrier. Methods 2003, 29:351-361. 10.1016/S1046-2023(02)00359-6, 12725802.
    • (2003) Methods , vol.29 , pp. 351-361
    • Eugenin, E.A.1    Berman, J.W.2
  • 33
    • 35649008926 scopus 로고    scopus 로고
    • Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors
    • 2190029, 17704824
    • O'Sullivan SE. Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors. Br J Pharmacol 2007, 152:576-582. 2190029, 17704824.
    • (2007) Br J Pharmacol , vol.152 , pp. 576-582
    • O'Sullivan, S.E.1
  • 34
    • 52949090419 scopus 로고    scopus 로고
    • CNS immune surveillance and neuroinflammation: endocannabinoids keep control
    • 10.2174/138161208785740090, 18781977
    • Wolf SA, Tauber S, Ullrich O. CNS immune surveillance and neuroinflammation: endocannabinoids keep control. Curr Pharm Des 2008, 14:2266-2278. 10.2174/138161208785740090, 18781977.
    • (2008) Curr Pharm Des , vol.14 , pp. 2266-2278
    • Wolf, S.A.1    Tauber, S.2    Ullrich, O.3
  • 35
    • 77955131100 scopus 로고    scopus 로고
    • Mending the broken brain: neuroimmune interactions in neurogenesis
    • Molina-Holgado E, Molina-Holgado F. Mending the broken brain: neuroimmune interactions in neurogenesis. J Neurochem 2010, 114:1277-1290.
    • (2010) J Neurochem , vol.114 , pp. 1277-1290
    • Molina-Holgado, E.1    Molina-Holgado, F.2
  • 36
    • 65449146377 scopus 로고    scopus 로고
    • Emerging strategies for exploiting cannabinoid receptor agonists as medicines
    • 10.1111/j.1476-5381.2008.00048.x, 2697681, 19226257
    • Pertwee RG. Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Br J Pharmacol 2009, 156:397-411. 10.1111/j.1476-5381.2008.00048.x, 2697681, 19226257.
    • (2009) Br J Pharmacol , vol.156 , pp. 397-411
    • Pertwee, R.G.1
  • 37
    • 37749034365 scopus 로고    scopus 로고
    • Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis
    • 10.1016/j.jneuroim.2007.10.024, 18037503
    • Croxford JL, Pryce G, Jackson SJ, Ledent C, Giovannoni G, Pertwee RG, Yamamura T, Baker D. Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis. J Neuroimmunol 2008, 193:120-129. 10.1016/j.jneuroim.2007.10.024, 18037503.
    • (2008) J Neuroimmunol , vol.193 , pp. 120-129
    • Croxford, J.L.1    Pryce, G.2    Jackson, S.J.3    Ledent, C.4    Giovannoni, G.5    Pertwee, R.G.6    Yamamura, T.7    Baker, D.8
  • 38
    • 0028971014 scopus 로고
    • Characteristics of cloned cerebrovascular endothelial cells following infection with Theiler's virus. II. Persistent infection
    • 10.1016/0165-5728(95)00094-4, 7499500
    • Sapatino BV, Petrescu AD, Rosenbaum BA, Smith R, Piedrahita JA, Welsh CJ. Characteristics of cloned cerebrovascular endothelial cells following infection with Theiler's virus. II. Persistent infection. J Neuroimmunol 1995, 62:127-135. 10.1016/0165-5728(95)00094-4, 7499500.
    • (1995) J Neuroimmunol , vol.62 , pp. 127-135
    • Sapatino, B.V.1    Petrescu, A.D.2    Rosenbaum, B.A.3    Smith, R.4    Piedrahita, J.A.5    Welsh, C.J.6
  • 39
    • 0031455406 scopus 로고    scopus 로고
    • Anti-adhesion molecule therapy in Theiler's murine encephalomyelitis virus-induced demyelinating disease
    • 10.1093/intimm/9.12.1837, 9466311
    • Inoue A, Koh CS, Yamazaki M, Ichikawa M, Isobe M, Ishihara Y, Yagita H, Kim BS. Anti-adhesion molecule therapy in Theiler's murine encephalomyelitis virus-induced demyelinating disease. Int Immunol 1997, 9:1837-1847. 10.1093/intimm/9.12.1837, 9466311.
    • (1997) Int Immunol , vol.9 , pp. 1837-1847
    • Inoue, A.1    Koh, C.S.2    Yamazaki, M.3    Ichikawa, M.4    Isobe, M.5    Ishihara, Y.6    Yagita, H.7    Kim, B.S.8
  • 40
    • 33748056090 scopus 로고    scopus 로고
    • The synthetic cannabinoid WIN 55,212-2 increases COX-2 expression and PGE2 release in murine brain-derived endothelial cells following Theiler's virus infection
    • 10.1016/j.bcp.2006.06.037, 16914119
    • Mestre L, Correa F, Docagne F, Clemente D, Guaza C. The synthetic cannabinoid WIN 55,212-2 increases COX-2 expression and PGE2 release in murine brain-derived endothelial cells following Theiler's virus infection. Biochem Pharmacol 2006, 72:869-880. 10.1016/j.bcp.2006.06.037, 16914119.
    • (2006) Biochem Pharmacol , vol.72 , pp. 869-880
    • Mestre, L.1    Correa, F.2    Docagne, F.3    Clemente, D.4    Guaza, C.5
  • 41
  • 43
    • 80052029691 scopus 로고    scopus 로고
    • Cannabinoid Receptor and N-acyl Phosphatidylethanolamine Phospholipase D-Evidence for Altered Expression in Multiple Sclerosis
    • Zhang H, Hilton DA, Hanemann CO, Zajicek J. Cannabinoid Receptor and N-acyl Phosphatidylethanolamine Phospholipase D-Evidence for Altered Expression in Multiple Sclerosis. Brain Pathol 2011,
    • (2011) Brain Pathol
    • Zhang, H.1    Hilton, D.A.2    Hanemann, C.O.3    Zajicek, J.4
  • 44
    • 33847420442 scopus 로고    scopus 로고
    • Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are specific markers of plaque cell subtypes in human multiple sclerosis
    • 10.1523/JNEUROSCI.4814-06.2007, 17329437
    • Benito C, Romero JP, Tolón RM, Clemente D, Docagne F, Hillard CJ, Guaza C, Romero J. Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are specific markers of plaque cell subtypes in human multiple sclerosis. J Neurosci 2007, 27:2396-402. 10.1523/JNEUROSCI.4814-06.2007, 17329437.
    • (2007) J Neurosci , vol.27 , pp. 2396-2402
    • Benito, C.1    Romero, J.P.2    Tolón, R.M.3    Clemente, D.4    Docagne, F.5    Hillard, C.J.6    Guaza, C.7    Romero, J.8
  • 45
    • 33645224970 scopus 로고    scopus 로고
    • COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord
    • 10.1186/1471-2377-6-12, 1413551, 16512913
    • Yiangou Y, Facer P, Durrenberger P, Chessell IP, Naylor A, Bountra C, Banati RR, Anand P. COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord. BMC Neurol 2006, 6:12. 10.1186/1471-2377-6-12, 1413551, 16512913.
    • (2006) BMC Neurol , vol.6 , pp. 12
    • Yiangou, Y.1    Facer, P.2    Durrenberger, P.3    Chessell, I.P.4    Naylor, A.5    Bountra, C.6    Banati, R.R.7    Anand, P.8
  • 46
    • 40749103882 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses Rho GTPases in human brain microvascular endothelial cells and inhibits adhesion and transendothelial migration of HIV-1 infected monocytes
    • Ramirez SH, Heilman D, Morsey B, Potula R, Haorah J, Persidsky Y. Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses Rho GTPases in human brain microvascular endothelial cells and inhibits adhesion and transendothelial migration of HIV-1 infected monocytes. J Immunol 2008, 180:1854-1865.
    • (2008) J Immunol , vol.180 , pp. 1854-1865
    • Ramirez, S.H.1    Heilman, D.2    Morsey, B.3    Potula, R.4    Haorah, J.5    Persidsky, Y.6
  • 47
    • 0031850964 scopus 로고    scopus 로고
    • Endothelial cells from diverse tissues exhibit differences in growth and morphology
    • 10.1006/mvre.1997.2045, 9473410
    • Craig LE, Spelman JP, Strandberg JD, Zink MC. Endothelial cells from diverse tissues exhibit differences in growth and morphology. Microvasc Res 1998, 55:65-76. 10.1006/mvre.1997.2045, 9473410.
    • (1998) Microvasc Res , vol.55 , pp. 65-76
    • Craig, L.E.1    Spelman, J.P.2    Strandberg, J.D.3    Zink, M.C.4
  • 48
    • 15744382273 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 by anandamide in cerebral microvascular endothelium
    • 10.1016/j.mvr.2005.02.001, 15797258
    • Chen P, Hu S, Yao J, Moore SA, Spector AA, Fang X. Induction of cyclooxygenase-2 by anandamide in cerebral microvascular endothelium. Microvasc Res 2005, 69:28-35. 10.1016/j.mvr.2005.02.001, 15797258.
    • (2005) Microvasc Res , vol.69 , pp. 28-35
    • Chen, P.1    Hu, S.2    Yao, J.3    Moore, S.A.4    Spector, A.A.5    Fang, X.6
  • 49
    • 49249094482 scopus 로고    scopus 로고
    • Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide
    • 10.1111/j.1460-9568.2008.06377.x, 18657182
    • Loría F, Petrosino S, Mestre L, Spagnolo A, Correa F, Hernangómez M, Guaza C, Di Marzo V, Docagne F. Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide. Eur J Neurosci 2008, 28:633-641. 10.1111/j.1460-9568.2008.06377.x, 18657182.
    • (2008) Eur J Neurosci , vol.28 , pp. 633-641
    • Loría, F.1    Petrosino, S.2    Mestre, L.3    Spagnolo, A.4    Correa, F.5    Hernangómez, M.6    Guaza, C.7    Di Marzo, V.8    Docagne, F.9
  • 50
    • 15244359387 scopus 로고    scopus 로고
    • Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis
    • 10.1111/j.1471-4159.2004.02979.x, 15748152
    • Mestre L, Correa F, Arévalo-Martín A, Molina-Holgado E, Valenti M, Ortar G, Di Marzo V, Guaza C. Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis. J Neurochem 2005, 92:1327-1339. 10.1111/j.1471-4159.2004.02979.x, 15748152.
    • (2005) J Neurochem , vol.92 , pp. 1327-1339
    • Mestre, L.1    Correa, F.2    Arévalo-Martín, A.3    Molina-Holgado, E.4    Valenti, M.5    Ortar, G.6    Di Marzo, V.7    Guaza, C.8
  • 51
    • 0038753984 scopus 로고    scopus 로고
    • CB(1) cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction
    • 10.1038/sj.bjp.0705156, 1573770, 12711625
    • Wagner JA, Hu K, Karcher J, Bauersachs J, Schäfer A, Laser M, Han H, Ertl G. CB(1) cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction. Br J Pharmacol 2003, 138:1251-1258. 10.1038/sj.bjp.0705156, 1573770, 12711625.
    • (2003) Br J Pharmacol , vol.138 , pp. 1251-1258
    • Wagner, J.A.1    Hu, K.2    Karcher, J.3    Bauersachs, J.4    Schäfer, A.5    Laser, M.6    Han, H.7    Ertl, G.8
  • 52
    • 5644220360 scopus 로고    scopus 로고
    • Endocannabinoids and their involvement in the neurovascular system
    • 10.2174/1567202043480107, 16185189
    • Battista N, Fezza F, Maccarrone M. Endocannabinoids and their involvement in the neurovascular system. Curr Neurovasc Res 2004, 1:129-140. 10.2174/1567202043480107, 16185189.
    • (2004) Curr Neurovasc Res , vol.1 , pp. 129-140
    • Battista, N.1    Fezza, F.2    Maccarrone, M.3
  • 53
    • 0141504950 scopus 로고    scopus 로고
    • Endothelin-1 increases 2-arachidonoyl glycerol (2-AG) production in astrocytes
    • 10.1002/glia.10270, 12951660
    • Walter L, Stella N. Endothelin-1 increases 2-arachidonoyl glycerol (2-AG) production in astrocytes. Glia 2003, 44:85-90. 10.1002/glia.10270, 12951660.
    • (2003) Glia , vol.44 , pp. 85-90
    • Walter, L.1    Stella, N.2
  • 54
    • 58049170379 scopus 로고    scopus 로고
    • Endocannabinoid signaling in microglial cells
    • 2654419, 18722389
    • Stella N. Endocannabinoid signaling in microglial cells. Neuropharmacology 2009, 56:244-253. 2654419, 18722389.
    • (2009) Neuropharmacology , vol.56 , pp. 244-253
    • Stella, N.1
  • 55
    • 38449086056 scopus 로고    scopus 로고
    • Endocannabinoids and traumatic brain injury
    • 10.1007/s12035-007-8008-6, 17952651
    • Mechoulam R, Shohami E. Endocannabinoids and traumatic brain injury. Mol Neurobiol 2007, 36:68-74. 10.1007/s12035-007-8008-6, 17952651.
    • (2007) Mol Neurobiol , vol.36 , pp. 68-74
    • Mechoulam, R.1    Shohami, E.2
  • 56
    • 33847657051 scopus 로고    scopus 로고
    • Immune control by endocannabinoids - new mechanisms of neuroprotection?
    • 10.1016/j.jneuroim.2006.11.018, 17196262
    • Ullrich O, Merker K, Timm J, Tauber S. Immune control by endocannabinoids - new mechanisms of neuroprotection?. J Neuroimmunol 2007, 184:127-135. 10.1016/j.jneuroim.2006.11.018, 17196262.
    • (2007) J Neuroimmunol , vol.184 , pp. 127-135
    • Ullrich, O.1    Merker, K.2    Timm, J.3    Tauber, S.4
  • 57
    • 66949113645 scopus 로고    scopus 로고
    • The innate immune response affects the development of the autoimmune response in Theiler's virus-induced demyelinating disease
    • 10.4049/jimmunol.0801940, 2876715, 19380818
    • Olson JK, Miller SD. The innate immune response affects the development of the autoimmune response in Theiler's virus-induced demyelinating disease. J Immunol 2009, 182:5712-5722. 10.4049/jimmunol.0801940, 2876715, 19380818.
    • (2009) J Immunol , vol.182 , pp. 5712-5722
    • Olson, J.K.1    Miller, S.D.2
  • 58
    • 0031866598 scopus 로고    scopus 로고
    • The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway
    • 10.1016/S0014-5793(98)00851-5, 9738948
    • Molina-Holgado F, Molina-Holgado E, Guaza C. The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway. FEBS Lett 1998, 433:139-142. 10.1016/S0014-5793(98)00851-5, 9738948.
    • (1998) FEBS Lett , vol.433 , pp. 139-142
    • Molina-Holgado, F.1    Molina-Holgado, E.2    Guaza, C.3
  • 59
    • 79954937143 scopus 로고    scopus 로고
    • The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: Evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells
    • 10.1016/j.bbi.2011.01.020, 21310228
    • Correa F, Hernangómez-Herrero M, Mestre L, Loría F, Docagne F, Guaza C. The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: Evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells. Brain Behav Immun 2011, 25:736-749. 10.1016/j.bbi.2011.01.020, 21310228.
    • (2011) Brain Behav Immun , vol.25 , pp. 736-749
    • Correa, F.1    Hernangómez-Herrero, M.2    Mestre, L.3    Loría, F.4    Docagne, F.5    Guaza, C.6
  • 60
    • 35448932890 scopus 로고    scopus 로고
    • Differential virus replication, cytokine production, and antigen-presenting function by microglia from susceptible and resistant mice infected with Theiler's virus
    • 10.1128/JVI.01034-07, 2168808, 17715222
    • Jin YH, Mohindru M, Kang MH, Fuller AC, Kang B, Gallo D, Kim BS. Differential virus replication, cytokine production, and antigen-presenting function by microglia from susceptible and resistant mice infected with Theiler's virus. J Virol 2007, 81:11690-11702. 10.1128/JVI.01034-07, 2168808, 17715222.
    • (2007) J Virol , vol.81 , pp. 11690-11702
    • Jin, Y.H.1    Mohindru, M.2    Kang, M.H.3    Fuller, A.C.4    Kang, B.5    Gallo, D.6    Kim, B.S.7
  • 62
    • 21744455710 scopus 로고    scopus 로고
    • Cannabinoid-receptor 1 null mice are susceptible to neurofilament damage and caspase 3 activation
    • Jackson SJ, Pryce G, Diemel LT, Cuzner ML, Baker D. Cannabinoid-receptor 1 null mice are susceptible to neurofilament damage and caspase 3 activation. Neuroscience 2005, 134:, 261-268.
    • (2005) Neuroscience , vol.134 , pp. 261-268
    • Jackson, S.J.1    Pryce, G.2    Diemel, L.T.3    Cuzner, M.L.4    Baker, D.5


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