Polypharmacy and medication-related complications in the chronic kidney disease patient

Current Opinion in Nephrology and Hypertension

Volumn 20, Issue 5, 2011, Pages 492-497

  Mason, Nancy A ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Renal Pharmacy Consultants LLC   (United States)

Author keywords

adherence; chronic kidney disease; interdisciplinary; medication reconciliation; medication related problems

Indexed keywords

ANTIHYPERTENSIVE AGENT; ERYTHROPOIETIN;

CHRONIC KIDNEY DISEASE; HEALTH CARE COST; HEALTH PROGRAM; HOSPITALIZATION; HUMAN; MEDICAL RECORD REVIEW; MEDICATION RELATED PROBLEM; MEDICATION THERAPY MANAGEMENT; PATIENT CARE; PATIENT COMPLIANCE; PHARMACEUTICAL CARE; PHARMACIST; POLYPHARMACY; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROBLEM SOLVING; QUALITY OF LIFE; REVIEW; STRUCTURED MEDICATION OPTIMIZATION; THERAPY; TREATMENT REFUSAL;

CHRONIC DISEASE; DRUG INTERACTIONS; DRUG THERAPY; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; KIDNEY DISEASES; MEDICATION ADHERENCE; MEDICATION ERRORS; MEDICATION RECONCILIATION; PATIENT EDUCATION AS TOPIC; POLYPHARMACY;

EID: 80051795950     PISSN: 10624821     EISSN: 14736543     Source Type: Journal    
DOI: 10.1097/MNH.0b013e328349c261     Document Type: Review

References (15)

1. Mason NA, Bakus JL Strategies for reducing polypharmacy and other medication-related problems in chronic kidney disease. Semin Dialysis 2010;23:55-61. This article reviews the issue of medication-related problems and is one of the first to provide the details for a structured medication optimization and reconciliation process.
2. Cardone KE, Bacchus S, Assimon MM, et al. Medication-related problems in CKD. Adv Chronic Kidney Dis 2010;17:404-412. This article summarizes the issues of medication-related problems in CKD and provides strategies for reduction and resolution of these problems.
3. Manley HJ, Cannella CA, Bailie GR, et al. Medication-related problems in ambulatory hemodialysis patients: a pooled analysis. Am J Kidney Dis 2005;46:669-680. (Pubitemid 41383945)
4. Pai AB, Boyd A, Depczynski J, et al. Reduced drug use and hospitalization rates in patients undergoing hemodialysis who received pharmaceutical care: a 2-year, randomized, controlled study. Pharmacotherapy 2009;29:1433-1440.
5. Pai AB, Boyd A, Chavez A, Manley HJ. Health-related quality of life is maintained in hemodialysis patients receiving pharmaceutical care: a 2-year randomized, controlled study. Hemodial Int 2009;13:72-79.
6. Ledger S, Choma G. Medication reconciliation in hemodialysis patients. Can Assoc Nephrol Nurse Technol J 2008;18:41-43.
7. Mirkov S. Implementation of a pharmacist medication review clinic for haemodialysis patients. New Zealand Med J 2009;122:25-37.
8. Browne T, Merighi JR. Barriers to adult hemodialysis patients' self-management of oral medications. Am J Kidney Dis 2010;56:547-557. This is a comprehensive review of hemodialysis patient adherence literature, including a proposed paradigm shift to a patient self-management model designed to enhance adherence.
9. National Council on Patient Information and Education. Enhancing prescription medication adherence: a national action plan. 2007. www.talkaboutrx.org/.../enhancing-prescription-medicine-adherence.pdf [Accessed 22 May 2011].
10. Schmitt KE, Edie CF, Laflam P, Simbartl LA. Adherence to antihypertensive agents and blood pressure control in chronic kidney disease. Am J Nephrol 2010;32:541-548. This study found that only 67% of CKD patients were adherent with their antihypertensive medications, and that nonadherence was associated with worse BP control.
11. Muntner P, Judd SE, Krousel-Wood M, et al. Low medication adherence and hypertension control among adults with CKD: data from the REGARDS (Reasons for Geographic and Racial Differences in Stroke) study. Am J Kidney Dis 2010;56:447-457. This study found that 69% of CKD patients are adherent with their antihypertensive agents and that nonadherence was related to higher rates of uncontrolled BP.
12. Katzir Z, Boaz M, Backshi I, et al. Medication apprehension and compliance among dialysis patients: a comprehensive guidance attitude. Nephron Clin Pract 2010;114:c151-c157. This study describes an educational intervention that was successful in improving adherence in hemodialysis patients.
13. Chang TI, Winkelmayer WC. Kidney disease and antihypertensive medication adherence: the need for improved measurement tools. Am J Kidney Dis 2010;56:423-436. This editorial reviews current approaches to medication nonadherence and discusses the need for better measures to be available at the time of clinical decisionmaking.
14. St Peter WL. Improving medication safety in chronic kidney disease patients on dialysis through medication reconciliation. Adv Chronic Kidney Dis 2010;17:413-419. This is a comprehensive review of evidence regarding the need for medication reconciliation and provides a structured approach and a list of data necessary to conduct this process.
15. Department of Health and Human Services, Center for Medicare and Medicaid Services. Conditions for coverage for end-stage renal disease facilities; final rule. https://www.cms.gov/cfcsandcops/downloads/esrdfinalrule0415.pdf [Accessed 21 May 2011].