On the protective effect of omega-3 against propionic acid-induced neurotoxicity in rat pups

Lipids in Health and Disease

Volumn 10, Issue , 2011, Pages

  El Ansary, Afaf K ^a   Al Daihan, Sooad K ^a   El Gezeery, Amina R ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Autism; Caspase 3; Cytokines; Neurotransmitters; Omega 3; Phospholipids; Propionic acid

Indexed keywords

4 AMINOBUTYRIC ACID; BRAIN PROTEIN; CASPASE 3; DOPAMINE; INTERLEUKIN 6; NEUROPROTECTIVE AGENT; OMEGA 3 FATTY ACID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLSERINE; PHOSPHOLIPID; PROPIONIC ACID; SEROTONIN; TUMOR NECROSIS FACTOR ALPHA; CASP3 PROTEIN, RAT; PROPIONIC ACID DERIVATIVE;

4 AMINOBUTYRIC ACID BRAIN LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN TISSUE; CONTROLLED STUDY; DOPAMINE BRAIN LEVEL; MALE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; RAT; SEROTONIN BRAIN LEVEL; ANIMAL; BRAIN; DRUG EFFECT; HUMAN; METABOLISM; RECEIVER OPERATING CHARACTERISTIC; TOXICITY AND INTOXICATION;

ANIMALIA; RATTUS;

ANIMALS; BRAIN; CASPASE 3; DOPAMINE; FATTY ACIDS, OMEGA-3; GAMMA-AMINOBUTYRIC ACID; HUMANS; INTERLEUKIN-6; MALE; NEUROPROTECTIVE AGENTS; NEUROTOXICITY SYNDROMES; PHOSPHOLIPIDS; PROPIONIC ACIDS; RATS; ROC CURVE; SEROTONIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80051787787     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-10-142     Document Type: Article

References (54)

1. Fetal mechanisms in neurodevelopmental disorders. Connors SL, Levitt P, Matthews SG, Slotkin TA, Johnston MV, Kinney HC, Johnson WG, Dailey RM, Zimmerman AW, Pediatr Neurol 2008 38 163 176 10.1016/j.pediatrneurol.2007.10.009 18279750 (Pubitemid 351221226)
2. Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates. Slotkin TA, Toxicology and Applied Pharmacology 2004 198 2 132 151 10.1016/j.taap.2003. 06.001 15236950 (Pubitemid 38960724)
3. Plasma fatty acid levels in autistic children. Vancassel S, Durand G, Barthélémy C, Lejeune B, Martineau J, Guilloteau D, Andrès C, Chalon S, Prostaglandins Leukot Essent Fatty Acids 2001 65 1 1 7 10.1054/plef.2001.0281 11487301 (Pubitemid 32783435)
4. Schizophrenia: the illness that made us human. Horrobin DF, Med Hypotheses 1998 50 4 269 88 10.1016/S0306-9877(98)90000-7 9690763 (Pubitemid 28231004)
5. Dietary omega-3 fatty acids for women. Bourre JM, Biomed Pharmacother 2007 61 2-3 105 12 10.1016/j.biopha.2006.09.015 17254747 (Pubitemid 46578282)
6. Deshpande: SB3-Nitropropionic acid depresses spinal reflexes involving GABAergic and glycinergic transmission in neonatal rat spinal cord in vitro. Gupta R, Life Sci 2008 83 21-22 756 60 10.1016/j.lfs.2008.09.017 18930740
7. 3H]-DA release evoked by low pH medium and internal H+ accumulation in rat hypothalamic synaptosomes: involvement of calcium ions. Cannizzaro C, Monastero R, Vacca M, Martire M, Neurochem Int 2003 43 9 17 10.1016/S0197-0186(02)00211-5 12605878 (Pubitemid 36246522)
8. Mid brain serotonergic receptors neurons are central pH chemoreceptors. Severson CA, Wang W, Pieribone VA, Dohle CI, Richerson GB, Nat Neurosci 2003 6 1139 40 10.1038/nn1130 14517544 (Pubitemid 37346031)
9. l-Carnitine enhances excretion ofpropionyl coenzymeA as propionyl carnitine in propionic acidemia. Roe CR, Millington DS, Maltby DA, Bohan TP, Hoppel CL, J Cli Invest 1984 73 1785 8 10.1172/JCI111387
10. The role of oxidative damage in the neuropathology of organic acidurias: insights from animal studies. Wajne M, Latin A, Wyse AT, Dutra-Filho CS, J Inherit Metab Dis 2004 27 427 48 15303000 (Pubitemid 39140134)
11. Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism. James SJ, Rose S, Melnyk S, Jernigan S, Blossom S, Pavliv O, et al. FASEBJ 2009 23 2374 83 10.1096/fj.08-128926
12. Relative carnitine deficiency in autism. Filipek PA, Jurane kJ, Nguyen MT, Cummings C, Gargus JJ, J Autism Dev Disord 2004 34 615 23 10.1007/s10803-004-5283-1 15679182 (Pubitemid 40044667)
13. Effects of the enteric bacterial metabolic product propionic acid on object-directed behavior, social behavior, cognition, and neuroinflammation in adolescent rats: Relevance to autism spectrum disorder. Macfabe DF, Cain NE, Boond F, Ossenkopp KP, Cain DP, Behavioural Brain Research 2011 217 1-2 47 54 20937326
14. Postmortem brain fatty acid profile of levodopa-treated Parkinson disease patients and parkinsonian monkeys. Julien C, Berthiaume L, Hadj-Taha A, Rajput AH, Bedard PJ, Di Paolo T, Julien P, Calon F, Neurochem Int 2006 48 404 414 10.1016/j.neuint.2005.12.002 16442670 (Pubitemid 43327280)
15. Mechanisms of action of docosahexaenoic acid in the nervous system. Salem N Jr, Litman B, Kim HY, Gawrisch K, Lipids 2001 36 945 960 10.1007/s11745-001- 0805-6 11724467
16. Modulation of lipid derived mediators by polyunsaturated fatty acids. Galli C, Marangoni F, Galella G, Prostaglandins Leukot Essent Fatty Acids 1993 48 51 55 10.1016/0952-3278(93)90009-L 8424123 (Pubitemid 23011113)
17. The emerging role of group VI calcium-independent phospholipase A2 in releasing docosahexaenoic acid from brain phospholipids. Green JT, Orr SK, Bazinet RP, J Lipid Res 2008 49 939 944
18. Neuroprotectin D1 (NPD1): a DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress. Bazan NG, Brain Pathol 2005 15 159 166 15912889 (Pubitemid 40546172)
19. Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression. Marcheselli VL, Hong S, Lukiw WJ, Tian XH, Gronert K, Musto A, Hardy M, Gimenez JM, Chiang N, Serhan CN, Bazan NG, J Biol Chem 2003 278 44 43807 17 10.1074/jbc.M305841200 12923200 (Pubitemid 37346009)
20. Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model. Calon F, Lim GP, Yang F, Morihara T, Teter B, Ubeda O, Rostaing P, Triller A, Salem N Jr, Ashe KH, Frautschy SA, Cole GM, Neuron 2004 43 633 645 10.1016/j.neuron.2004.08.013 15339646 (Pubitemid 39179724)
21. Docosahexaenoic acid provides protection from impairment of learning ability in Alzheimer's disease model rats. Hashimoto S, Hossain T, Shimad K, Sugioka H, Yamasaki Y, Fujii Y, Ishibashi Y, Oka J, Shido O, J Neurochem 2002 81 1084 1091 10.1046/j.1471-4159.2002.00905.x 12065621 (Pubitemid 34809291)
22. Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease. Calon F, Lim GP, Morihara T, Yang F, Ubeda O, Salem N, Frautschy SA, Cole GM, Eur J Neurosci 2005 22 617 626 10.1111/j.1460-9568.2005.04253.x 16101743 (Pubitemid 41192272)
23. L-2-Chloropropionic acid metabolism and disposition in male rats: relevance to cerebellar injury. Wyatt I, Farnworth M, Gyte AJ, Lock EA, Arch Toxicol 1997 71 11 668 76 10.1007/s002040050443 9363839 (Pubitemid 27427513)
24. A rapid method of total lipid extraction and purification. Bligh EG, Dyer WJ, Can J Biochem Physiol 1959 37 8 911 7 10.1139/o59-099 13671378
25. Neurobiological effects of intraventricular propionic acid in rats: Possible role of short chain fatty acids on the pathogenesis and characteristics of autism spectrum disorders. MacFabe DF, Cain DP, Rodriguez-Capote K, Franklin AE, Hoffman JE, Boond F, Taylor AR, Kavaliers M, Ossenkopp KP, Behavioural Brain Research 2007 176 149 169 10.1016/j.bbr.2006.07.025 16950524 (Pubitemid 44895353)
26. Docosahexaenoic acid, fatty acid-interacting proteins, and neuronal function: breastmilk and fish are good for you. Marszalek JR, Lodish HF, Ann Rev Cell Dev Biol 2005 21 633 657 10.1146/annurev.cellbio.21.122303.120624 (Pubitemid 41740649)
27. Roles of unsaturated fatty acids (especially omega-3 fatty acids) in the brain at various ages and during ageing. Bourre JM, J Nutr 2004 8 163 174 (Pubitemid 38678591)
28. Changing fatty acid content of growth cone lipids prior to synaptogenesis. Martin RE, Bazan NG, J Neurochem 1992 59 318 325 10.1111/j.1471-4159.1992.tb08906.x 1613507
29. Dietary Omega-3 fatty acids attenuate cellular damage after a hippocampal ischemic insult in adult rats. Moreira JD, Knorr L, Thomazi AP, Sima F, Battu C, Oses JP, Gottfried C, Wofchuk S, Salbego C, Souza DO, Perry MLS, Vinade L, Jouranl of Nutrition Biochemistry 2010 21 4 351 6 10.1016/j.jnutbio.2009.01.013
30. Modifications of dopamine neurotransmission in the nucleous accumbens of rats deficient in n-3 polyunsaturated fatty acids. Zimmer L, Delion-Vancassel S, Durand G, Guilloteau D, Bodard S, Besnard JC, Chalon S, J Lipid Res 2000 41 32 40 10627499 (Pubitemid 30051839)
31. Glutamate transporters: confining runaway excitation by shaping synaptic transmission. Tzingounis AV, Wadiche JI, Nat Rev Neurosci 2007 8 12 935 947 10.1038/nrn2274 17987031 (Pubitemid 350146934)
32. Phospholipid supplementation reverses behavioral and biochemical alterations inducedby n-3 polyunsaturated fatty acid deficiency in mice. Carrie I, Cle'ment M, de Javel D, France's H, Bourre JM, J Lipid Res 2000 41 3 473 480 10706595 (Pubitemid 30183630)
33. Behavioral deficits associated with dietary induction of decreased brain docosahexaenoic acid concentration. Moriguchi T, Greiner RS, Salem N, J Neurochem 2000 75 6 2563 2573 11080210
34. Possible regulatory mechanism of DHA induced anti-stress reaction in rats. Takeuchi T, Iwanaga M, Harada E, Brain Res 2003 964 1 136 143 10.1016/S0006-8993(02)04113-6 12573522 (Pubitemid 36165079)
35. An (n-3) polyunsaturated fatty acid-deficient diet disturbs daily locomotor activity, melatonin rhythm, and striatal dopamine in Syrian hamsters. Lavialle M, Champeil-Potokar G, Alessandri JM, Balasse L, Guesnet P, Papillon C, Pe' vet P, Vancassel S, Vivien-Roels B, Denis I, J Nutr 2008 138 9 1719 1724 18716175
36. Dietary omega-3 Fatty acids and psychiatry: mood, behaviour, stress, depression, dementia and aging. Bourre JM, J Nutr Health Aging 2005 9 1 31 8 15750663
37. Cascading effects of stressors and inflammatory immune system activation: implications for major depressive disorder. Anisman H, J Psychiatry Neurosci 2009 34 4 20 19125209
38. Inflammation modulates anxiety in ananimal model of multiple sclerosis. Hartwig S, Thöne J, Hovemann B, Gold R, Juckelc G, Linker RA, Perugaa I, Behavioural Brain Research 2011 220 20 29 10.1016/j.bbr.2011.01.018 21255614
39. The omega-3 fatty acid, DHA, decreases neuronal cell death in association with altered zinc transport. Suphioglu C, De Mel D, Kumar L, Sadli N, Freestone D, Michalczyk A, Sinclair A, Leigh Ackland M, FEBS Letters 2010 584 612 618 10.1016/j.febslet.2009.12.013 20006607
40. Docosahexaenoic acid: a positive modulator of Akt signaling in neuronal survival. Akbar M, Calderon F, Wen Z, Kim HY, Proc Natl Acad Sci USA 2005 102 10858 10863 10.1073/pnas.0502903102 16040805 (Pubitemid 41105957)
41. Omega-3 fatty acid eicosapentaenoic acid (EPA), a new drug in treatment psychiatric and neurodegenerative diseases: a review of clinical trials. Song C, Zhao S, Exp Opin Inv Drug 2007 16 1627 38 10.1517/13543784.16.10.1627 (Pubitemid 350028412)
42. Omega-3 fatty acids upregulate adult neurogenesis. Beltz BS, Tlusty MF, Benton JL, Sandeman DC, Neurosci Lett 2007 145 154 8 (Pubitemid 46394591)
43. Increased phospholipase A2 activity and inflammatory response but decreased nerve growth factor expression in the olfactory bulbectomized rat model of depression: effects of chronic ethyl-eicosapentaenoate treatment. Song C, Zhang XY, Manku M, J Neurosci 2009 29 14 22 19129380
44. Changes in hippocampal IL-15, related cytokines, and neurogenesis in IL-2 deficient mice. Beck RD Jr, Wasserfull C, Ha GK, Cushman JD, Huang Z, Atkinson MA, Petitto JM, Brain Res 2005 1041 223 30 10.1016/j.brainres.2005.02.010 15829231
45. Reductions of acetylcholine release and nerve growth factor expression are correlated with memory impairment induced by interleukin-1beta administrations: effects of omega-3 fatty acid EPA treatment. Taepavarapruk P, Song C, J Neurochem 2010 112 1054 64 10.1111/j.1471-4159.2009.06524.x 19968753
46. Effect of long-lasting serotonin depletion on environmental enrichment-induced neurogenesis in adult rat hippocampus and spatial learning. Ueda S, Sakakibara S, Yoshimoto K, Neuroscience 2005 135 395 402 10.1016/j.neuroscience.2005.06.065 16125851 (Pubitemid 41317378)
47. Regulation of life-long neurogenesis in the decapod crustacean brain. Beltz BS, Sandeman DC, Arth Struct Dev 2003 32 39 60 10.1016/S1467-8039(03) 00038-0 (Pubitemid 37152835)
48. Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats. Wu A, Ying Z, Gomez-Pinilla F, J Neurotrauma 2004 21 1457 67 10.1089/neu.2004.21.1457 15672635 (Pubitemid 39435321)
49. Eicosapentaenoic acid (EPA) increases cell viability and expression of neurotrophin receptors in retinoic acid and brain-derived neurotrophic factor Differentiated SH-SY5Y cells. Kou W, Luchtman D, Song C, Eur J Nutr 2008 47 104 13 10.1007/s00394-008-0703-1 18360785 (Pubitemid 351667054)
50. Effect of in vivo modulation of membrane docosahexaenoic acid levels on the dopamine-dependent adenylate cyclase activity in rat retina. Malnoe A, Milon H, Reme C, J Neurochem 1990 55 1480 1485 10.1111/j.1471-4159.1990.tb04929.x 2145395
51. Characterization of the influence of unsaturated free fatty acids on brain GABA/benzodiazepine receptor binding in vitro. Witt MR, Nielsen M, J Neurochem 1994 62 1432 1439 8133272 (Pubitemid 24098093)
52. Reduced numbers of dopamine neurons in the substantia nigra pars compactaand ventral tegmental area of rats fed an n-3 polyunsaturatedfatty acid-deficient diet: A stereological study. Ahmada SO, Park JH, Radel JD, Levant B, Neuroscience Letters 2008 438 303 307 10.1016/j.neulet.2008.04.073 18499349
53. Depressive-like behaviors alterations induced by intranigral MPTP, 6-OHDA, LPS and rotenone models of Parkinson's disease are predominantly associated with serotonin and dopamine. Santiago RM, Barbieiro J, Lima MM, Dombrowski PA, Andreatini R, Vital MA, Prog Neuropsychopharmacol Biol Psychiatry 2010 34 1104 14 10.1016/j.pnpbp.2010.06.004 20547199
54. Chronic -3 fatty acids supplementation promotes beneficial effects on anxiety, cognitive and depressive-like behaviors in rats subjected to a restraint stress protocol. Ferraz AC, Delattrea AM, Almendra RG, Sonaglia M, Borges C, Araujo P, Andersen ML, Tufik S, Lima MMS, Behavioural Brain Research 2011 219 116 122 10.1016/j.bbr.2010.12.028 21192985