Camptothecin-induced downregulation of MLL5 contributes to the activation of tumor suppressor p53

Oncogene

Volumn 30, Issue 33, 2011, Pages 3599-3611

  Cheng, F ^a   Liu, J ^a   Teh, C ^b   Chong, S W ^b   Korzh, V ^b   Jiang, Y J ^b,c   Deng, L W ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

camptothecin; MLL5; p53; p53 tetramer; Serine 392

Indexed keywords

CAMPTOTHECIN; DNA; MESSENGER RNA; MIXED LINEAGE LEUKEMIA 5 PROTEIN; PROTEIN; PROTEIN P53; SERINE; TETRAMER; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER CELL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA REPLICATION; DOWN REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; CELL CYCLE PROTEINS; CHROMATIN; DNA REPLICATION; DNA-BINDING PROTEINS; DOWN-REGULATION; HCT116 CELLS; HEK293 CELLS; HUMANS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; ZEBRAFISH;

DANIO RERIO;

EID: 80051786169     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.71     Document Type: Article

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