Serum calcium is positively correlated with fasting plasma glucose and insulin resistance, independent of parathyroid hormone, in male patients with type 2 diabetes mellitus

Metabolism: Clinical and Experimental

Volumn 60, Issue 9, 2011, Pages 1334-1339

  Yamaguchi, Toru ^a   Kanazawa, Ippei ^a   Takaoka, Shin ^a   Sugimoto, Toshitsugu ^a  

^a SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; CALCIUM; CREATININE; ESTRADIOL; GLUCOSE; IMMUNOREACTIVE INSULIN; PARATHYROID HORMONE; PHOSPHATE;

ADULT; ALBUMIN BLOOD LEVEL; ARTICLE; BODY HEIGHT; BODY WEIGHT; BONE METABOLISM; CALCIUM BLOOD LEVEL; CALCIUM HOMEOSTASIS; CREATININE BLOOD LEVEL; CROSS-SECTIONAL STUDY; DIABETIC PATIENT; ESTRADIOL BLOOD LEVEL; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PHOSPHATE BLOOD LEVEL; PRIORITY JOURNAL;

ADULT; AGED; BLOOD GLUCOSE; CALCIUM; DIABETES MELLITUS, TYPE 2; FASTING; FEMALE; HUMANS; INSULIN RESISTANCE; MALE; MIDDLE AGED; PARATHYROID HORMONE; REGRESSION ANALYSIS; VITAMIN D;

EID: 80051782872     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2011.02.003     Document Type: Article

References (36)

1. 2+ and other ions as extracellular (first) messengers Physiol Rev 71 1991 371 411
2. D. Pietrobon, F. Di Virgilio, and T. Pozzan Structural and functional aspects of calcium homeostasis in eukaryotic cells Eur J Biochem 193 1990 599 622 (Pubitemid 20381689)
3. E.M. Brown The calcium-sensing receptor: physiology, pathophysiology and CaR-based therapeutics Subcell Biochem 45 2007 139 167
4. S. Sajid-Crockett, F.R. Singer, and J.M. Hershman Cinacalcet for the treatment of primary hyperparathyroidism Metabolism 57 2008 517 521 (Pubitemid 351317967)
5. N. Chattopadhyay, and E.M. Brown Role of calcium-sensing receptor in mineral ion metabolism and inherited disorders of calcium-sensing Mol Genet Metab 89 2006 189 202 (Pubitemid 44442994)
6. 2+-sensitive nonselective cation channels in regulating the membrane potential of pancreatic beta-cells Diabetes 47 1998 1066 1073 (Pubitemid 28294549)
7. 2+-sensing receptor with the inwardly rectifying potassium channels Kir4.1 and Kir4.2 results in inhibition of channel function Am J Physiol Renal Physiol 292 2007 F1073 F1081
8. J. Parkash Glucose-mediated spatial interactions of voltage dependent calcium channels and calcium sensing receptor in insulin producing β-cells Life Sci 2010 10.1016/j.lfs.2010.12.002
9. W.H. Taylor, and A.A. Khaleeli Coincident diabetes mellitus and primary hyperparathyroidism Diabetes Metab Res Rev 17 2001 175 180 (Pubitemid 32624600)
10. M. Procopio, G. Magro, and F. Cesario The oral glucose tolerance test reveals a high frequency of both impaired glucose tolerance and undiagnosed type 2 diabetes mellitus in primary hyperparathyroidism Diabet Med 19 2002 958 961 (Pubitemid 35356924)
11. M.L. Richards, and N.W. Thompson Diabetes mellitus with hyperparathyroidism: another indication for parathyroidectomy? Surgery 126 1999 1160 1166
12. S. Akgun, and N.H. Ertel Hyperparathyroidism and coexisting diabetes mellitus. Altered carbohydrate metabolism Arch Intern Med 138 1978 1500 1502 (Pubitemid 9257977)
13. A. Kautzky-Willer, G. Pacini, and B. Niederle Insulin secretion, insulin sensitivity and hepatic insulin extraction in primary hyperparathyroidism before and after surgery Clin Endocrinol (Oxf) 37 1992 147 155
14. J.D. Quin, and J.R. Gumpert Remission of non-insulin-dependent diabetes mellitus following resection of a parathyroid adenoma Diabet Med 14 1997 80 81 (Pubitemid 27019927)
15. G. Sun, S. Vasdev, and G.R. Martin Altered calcium homeostasis is correlated with abnormalities of fasting serum glucose, insulin resistance, and beta-cell function in the Newfoundland population Diabetes 54 2005 3336 3339 (Pubitemid 43334392)
16. K.C. Chiu, L.M. Chuang, and N.P. Lee Insulin sensitivity is inversely correlated with plasma intact parathyroid hormone level Metabolism 49 2000 1501 1505
17. I. Kanazawa, T. Yamaguchi, and T. Sugimoto Baseline serum total adiponectin level is positively associated with changes in bone mineral density after 1-year treatment of type 2 diabetes mellitus Metabolism 59 2010 1252 1256
18. R.B. Payne, A.J. Little, and R.B. Williams Interpretation of serum calcium in patients with abnormal serum proteins Br Med J 4 1973 643 646
19. S.R. Nussbaum, R.J. Zahradnik, and J.R. Lavigne Highly sensitive two-site immunoradiometric assay of parathyrin, and its clinical utility in evaluating patients with hypercalcemia Clin Chem 33 1987 1364 1367 (Pubitemid 18041971)
20. D.R. Matthews, J.P. Hosker, and A.S. Rudenski Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 1985 412 419 (Pubitemid 15018832)
21. J.C. Henquin, M.A. Ravier, and M. Nenquin Hierarchy of the beta-cell signals controlling insulin secretion Eur J Clin Invest 33 2003 742 750 (Pubitemid 37082859)
22. 2+ Cell Calcium 11 1990 547 556 (Pubitemid 20336058)
23. G. Molostvov, S. James, and S. Fletcher Extracellular calcium-sensing receptor is functionally expressed in human artery Am J Physiol Renal Physiol 293 2007 F946 955
24. K. Aoki, and K. Miyagawa Correlation of increased serum calcium with elevated blood pressure and vascular resistance during calcium infusion in normotensive man J Hypertens 8 1990 579 583 (Pubitemid 20301435)
25. P. McNair, M.S. Christensen, and S. Madsbad Hypoparathyroidism in diabetes mellitus Acta Endocrinol (Copenh) 96 1981 81 86 (Pubitemid 11133842)
26. N.C. Thalassinos, P. Hadjiyanni, and M. Tzanela Calcium metabolism in diabetes mellitus: effect of improved blood glucose control Diabet Med 10 1993 341 344 (Pubitemid 23134742)
27. T. Kawagishi, H. Morii, and K. Nakatsuka Parathyroid hormone secretion in diabetes mellitus Contrib Nephrol 90 1991 217 222
28. T. Sugimoto, C. Ritter, and J. Morrissey Effects of high concentrations of glucose on PTH secretion in parathyroid cells Kidney Int 37 1990 1522 1527 (Pubitemid 20198035)
29. T. Yamamoto, K. Ozono, and A. Miyauchi Role of advanced glycation end products in adynamic bone disease in patients with diabetic nephropathy Am J Kidney Dis 38 2001 S161 S164
30. S. Khosla, L.J. Melton III, and B.L. Riggs The unitary model for estrogen deficiency and the pathogenesis of osteoporosis: is a revision needed? J Bone Miner Res 2010 [Epub ahead of print]
31. I. Kanazawa, T. Yamaguchi, and M. Yamamoto Serum insulin-like growth factor-I level is associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes mellitus Osteoporos Int 18 2007 1675 1681 (Pubitemid 47620319)
32. M. Yamamoto, T. Yamaguchi, and M. Yamauchi Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes J Clin Endocrinol Metab 93 2008 1013 1019 (Pubitemid 351398587)
33. I. Kanazawa, T. Yamaguchi, and M. Yamamoto Relationships between serum adiponectin levels versus bone mineral density, bone metabolic markers, and vertebral fractures in type 2 diabetes mellitus Eur J Endocrinol 160 2009 265 273
34. T. Takiishi, C. Gysemans, and R. Bouillon Vitamin D and diabetes Endocrinol Metab Clin North Am 39 2010 419 446
35. J.F. Aloia, D.G. Chen, and H. Chen The 25(OH)D/PTH threshold in black women J Clin Endocrinol Metab 95 2010 5069 5073
36. R. Okazaki, T. Sugimoto, and H. Kaji Vitamin D insufficiency defined by serum 25-hydroxyvitamin D and parathyroid hormone before and after oral vitamin D(3) load in Japanese subjects J Bone Miner Metab 29 2011 103 110