Chronic continuous positive airway pressure (CPAP) reduces airway reactivity in vivo in an allergen-induced rabbit model of asthma

Journal of Applied Physiology

Volumn 111, Issue 2, 2011, Pages 353-357

  Xue, Z ^a   Yu, Y ^a   Gao, H ^a   Gunst, S J ^a   Tepper, R S ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RILEY HOSPITAL FOR CHILDREN   (United States)

Author keywords

Airway inflammation; Chronic mechanical strain

Indexed keywords

ACETYLCHOLINE; ALLERGEN; BRONCHOCONSTRICTING AGENT; OVALBUMIN;

AIRWAY RESISTANCE; ANIMAL; ARTICLE; ASTHMA; BIOMECHANICS; BRONCHUS HYPERREACTIVITY; CYTOLOGY; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; LUNG LAVAGE; MALE; PATHOPHYSIOLOGY; PHYSIOLOGY; POSITIVE END EXPIRATORY PRESSURE; RABBIT;

ACETYLCHOLINE; AIRWAY RESISTANCE; ALLERGENS; ANIMALS; ASTHMA; BIOMECHANICS; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOCONSTRICTOR AGENTS; CONTINUOUS POSITIVE AIRWAY PRESSURE; HYPERSENSITIVITY, IMMEDIATE; IMMUNOHISTOCHEMISTRY; MALE; OVALBUMIN; RABBITS;

EID: 80051775437     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01345.2010     Document Type: Article

References (29)

1. Allen ND, Davis BE, Cockcroft DW. Correlation between airway inflammation and loss of deep-inhalation bronchoprotection in asthma. Ann Allergy Asthma Immunol 101: 413-418, 2008.
2. Alonso-Fernández A, García-Río F, Arias MA, Hernanz Á, de la Peña M, Piérola J, Barceló A, López-Collazo E, Agustí A. Effects of CPAP on oxidative stress and nitrate efficiency in sleep apnoea: a randomized trial. Thorax 64: 581-586, 2009.
3. Bosse Y, Sobieszek A, Pare PD, Seow CY. Length adaptation of airway smooth muscle. Proc Am Thoracic Soc 5: 62-67, 2008.
4. Brown R, Mitzner W. Duration of deep inspiration and subsequent airway constriction in vivo. J Asthma 40: 119-124, 2003. (Pubitemid 36576472)
5. Chan KN, Noble-Jamieson CM, Elliman A, Bryan EM, Aber VR, Silverman M. Airway responsiveness in low birthweight children and their mothers. Arch Dis Child 63: 905-910, 1988.
6. Fahy JV. Goblet cell and mucin gene abnormalities in asthma. Chest 122: 320S-326S, 2002. (Pubitemid 36043022)
7. Fish JE, Ankin MG, Kelly JF, Peterman VI. Regulation of bronchomotor tone by lung inflation in asthmatic and nonasthmatic subjects. J Appl Physiol 50: 1079-1086, 1981. (Pubitemid 11107545)
8. Groneberg DA, Eynott PR, Lim S, Oates T, Wu R, Carlstedt I, Roberts P, McCann B, Nicholson AG, Harrison BD, Chung KF. Expression of respiratory mucins in fatal status asthmaticus and mild asthma. Histopathology 40: 367-373, 2002. (Pubitemid 34595588)
9. Gunst SJ, Tang DD, Opazo SA. Cytoskeletal remodeling of the airway smooth muscle cell: a mechanism for adaptation to mechanical forces in the lung. Respir Physiol Neurobiol 137: 151-168, 2003. (Pubitemid 37153280)
10. Gunst SJ, Wu MF. Selected contribution: Plasticity of airway smooth muscle stiffness and extensibility: role of length-adaptive mechanisms. J Appl Physiol 90: 741-749, 2001. (Pubitemid 32118938)
11. Ip MS, Lam B, Chan LY, Zheng L, Tsang KW, Fung PC, Lam WK. Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by nasal continuous positive airway pressure. Am J Respir Crit Care Med 162: 2166-2171, 2000. (Pubitemid 32051681)
12. Kapsali T, Permutt S, Laube B, Scichilone N, Togias A. Potent bronchoprotective effect of deep inspiration and its absence in asthma. J Appl Physiol 89: 711-720, 2000. (Pubitemid 30637122)
13. King GG, Moore BJ, Seow CY, Pare PD. Time course of increased airway narrowing caused by inhibition of deep inspiration during methacholine challenge. Am J Respir Crit Care Med 160: 454-457, 1999. (Pubitemid 29380657)
14. Lafond C, Series F, Lemiere C. Impact of CPAP on asthmatic patients with obstructive sleep apnoea. Eur Respir J 29: 307-311, 2007. (Pubitemid 46231908)
15. Lin CC, Lin CY. Obstructive sleep apnea syndrome and bronchial hyperreactivity. Lung 173: 117-126, 1995.
16. Malmberg P, Larsson K, Sundblad BM, Zhiping W. Importance of the time interval between FEV1 measurements in the methacholine provocation test. Eur Respir J 6: 680-686, 1993. (Pubitemid 23160265)
17. Mehta D, Wu MF, Gunst SJ. Role of contractile protein activation in the length-dependent modulation of tracheal smooth muscle force. Am J Physiol Cell Physiol 270: C243-C252, 1996.
18. Minoguchi K, Yokoe T, Tanaka A, Ohta S, Hirano T, Yoshino G, O'Donnell CP, Adachi M. Association between lipid peroxidation and inflammation in obstructive sleep apnoea. Eur Respir J 28: 378-385, 2006. (Pubitemid 44914239)
19. Pyrgos G, Kapsali T, Permutt S, Togias A. Absence of deep inspirationinduced bronchoprotection against inhaled allergen. Am J Respir Crit Care Med 167: 1660-1663, 2003. (Pubitemid 36760680)
20. Salome CM, Thorpe CW, Diba C, Brown NJ, Berend N, King GG. Airway re-narrowing following deep inspiration in asthmatic and nonasthmatic subjects. Eur Respir J 22: 62-68, 2003. (Pubitemid 36896472)
21. Scichilone N, Permutt S, Togias A. The lack of the bronchoprotective and not the bronchodilatory ability of deep inspiration is associated with airway hyperresponsiveness. Am J Respir Crit Care Med 163: 413-419, 2001. (Pubitemid 32158521)
22. Slats AM, Janssen K, de Jeu RC, van der Plas DT, Schot R, van den Aardweg JG, Sterk PJ. Enhanced airway dilation by positive-pressure inflation of the lungs compared with active deep inspiration in patients with asthma. J Appl Physiol 105: 1725-1732, 2008.
23. Tang DD, Gunst SJ. Selected contribution: roles of focal adhesion kinase and paxillin in the mechanosensitive regulation of myosin phosphorylation in smooth muscle. J Appl Physiol 91: 1452-1459, 2001. (Pubitemid 32803945)
24. Wang L, Liu HW, McNeill KD, Stelmack G, Scott JE, Halayko AJ. Mechanical strain inhibits airway smooth muscle gene transcription via protein kinase C signaling. Am J Respir Cell Mol Biol 31: 54-61, 2004. (Pubitemid 38888039)
25. Wu Y, Huang Y, Herring BP, Gunst SJ. Integrin-linked kinase regulates smooth muscle differentiation marker gene expression in airway tissue. Am J Physiol Lung Cell Mol Physiol 295: L988-L997, 2008.
26. Xue Z, Zhang L, Liu Y, Gunst SJ, Tepper RS. Chronic inflation of ferret lungs with CPAP reduces airway smooth muscle contractility in vivo and in vitro. J Appl Physiol 104: 610-615, 2008. (Pubitemid 351468787)
27. Xue Z, Zhang L, Ramchandani R, Liu Y, Antony VB, Gunst SJ, Tepper RS. Respiratory system responsiveness in rabbits in vivo is reduced by prolonged continuous positive airway pressure. J Appl Physiol 99: 677-682, 2005. (Pubitemid 41061165)
28. Yokoe T, Minoguchi K, Matsuo H, Oda N, Minoguchi H, Yoshino G,Hirano T, dachi M. Elevated levels of C-reactive protein and interleukin- 6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure. Circulation 107: 1129-1134, 2003. (Pubitemid 36297204)
29. Zhao R, Du L, Huang Y, Wu Y, Gunst SJ. Actin depolymerization factor/cofilin activation regulates actin polymerization and tension development in canine tracheal smooth muscle. J Biol Chem 283: 36522-36531, 2008.