Detecting rejection after mouse islet transplantation utilizing islet protein-stimulated ELISPOT

Cell Transplantation

Volumn 20, Issue 6, 2011, Pages 955-962

  Toso, Christian ^a   Pawlick, Rena ^b   Lacotte, Stéphanie ^a   Edgar, Ryan ^b   Davis, Joy ^b   Mccall, Michael ^b   Morel, Philippe ^a   Mentha, Gilles ^a   Berney, Thierry ^a   James Shapiro, A M ^b  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Cytokine; Diabetes; Islets; Monitoring; Transplantation

Indexed keywords

ABATACEPT; GAMMA INTERFERON;

ALLOIMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CELL STIMULATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSPOT ASSAY; EX VIVO STUDY; FEMALE; GRAFT REJECTION; IMMUNE RESPONSE; IMMUNOREACTIVITY; MOUSE; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; RAT; SPLEEN CELL;

ANIMALS; AUTOIMMUNITY; CYTOKINES; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSPOT ASSAY; FEMALE; GRAFT REJECTION; IMMUNOSUPPRESSIVE AGENTS; INTERFERON-GAMMA; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED NOD; ROC CURVE; SPLEEN; TRANSPLANTATION, AUTOLOGOUS; TRANSPLANTATION, HOMOLOGOUS;

MUS;

EID: 80051757947     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368910X539137     Document Type: Article

References (39)

1. Ashton-Chess J.; Giral M.; Soulillou J. P.; Brouard S. Can immune monitoring help to minimize immunosuppression in kidney transplantation? Transpl. Int. 22:110-119; 2009.
2. Augustine J. J.; Poggio E. D.; Heeger P. S.; Hricik D. E. Preferential benefit of antibody induction therapy in kidney recipients with high pretransplant frequencies of donor-reactive interferon-gamma enzyme-linked immunosorbent spots. Transplantation 86:529-534; 2008.
3. Augustine J. J.; Siu D. S.; Clemente M. J.; Schulak J. A.; Heeger P. S.; Hricik D. E. Pre-transplant IFN-gamma ELISPOTs are associated with post-transplant renal function in African American renal transplant recipients. Am. J. Transplant. 5:1971-1975; 2005.
4. Bellin M. D.; Kandaswamy R.; Parkey J.; Zhang H. J.; Liu B.; Ihm S. H.; Ansite J. D.; Witson J.; Bansal- Pakala P.; Balamurugan A. N.; Papas K.; Sutherland D. E.; Moran A.; Hering B. J. Prolonged insulin independence after islet allotransplants in recipients with type 1 diabetes. Am. J. Transplant. 8(11):2463-2470; 2008.
5. Berney T.; Mamin A.; Shapiro A. M. J.; Ritz-Laser B.; Brulhart M. C.; Toso C.; Demuylder-Mischler S.; Armanet M.; Baertschiger R.; Wojtusciszyn A.; Benhamou P. Y.; Bosco D.; Morel P.; Philippe J. Detection of insulin mRNA in the peripheral blood after human islet transplantation predicts deterioration of metabolic control. Am. J. Transplant. 6:1704-1711; 2006.
6. Berney T.; Toso C. Monitoring of the islet graft. Diabetes Metab. 32:503-512; 2006.
7. Bestard O.; Nickel P.; Cruzado J. M.; Schoenemann C.; Boenisch O.; Sefrin A.; Grinyo J. M.; Volk H. D.; Reinke P. Circulating alloreactive T cells correlate with graft function in longstanding renal transplant recipients. J. Am. Soc. Nephrol. 19:1419-1429; 2008.
8. CITR Research Group. 2007 update on allogeneic islet transplantation from the Collaborative Islet Transplant Registry (CITR). Cell Transplant. 18:753-767; 2009.
9. Costa V. S.; Mattana T. C.; da Silva M. E. Unregulated IL-23/IL-17 immune response in autoimmune diseases. Diabetes Res. Clin. Pract. 88:222-226; 2010.
10. Dinavahi R.; Heeger P. S. T-Cell immune monitoring in organ transplantation. Transplantation 88:1157-1158; 2009.
11. Emamaullee J. A.; Davis J.; Merani S.; Toso C.; Elliott J. F.; Thiesen A.; Shapiro A. M. Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice. Diabetes 58:1302-1311; 2009.
12. Emamaullee J. A.; Davis J.; Pawlick R.; Toso C.; Merani S.; Cai S. X.; Tseng B.; Shapiro A. M. Caspase inhibitor therapy synergizes with costimulation blockade to promote indefinite islet allograft survival. Diabetes 59:1469-1477; 2010.
13. Enee E.; Martinuzzi E.; Blancou P.; Bach J. M.; Mallone R.; van Endert P. Equivalent specificity of peripheral blood and islet-infiltrating CD8+ T lymphocytes in spontaneously diabetic HLA-A2 transgenic NOD mice. J. Immunol. 180:5430-5438; 2008.
14. Eriksson O.; Eich T.; Sundin A.; Tibell A.; Tufveson G.; Andersson H.; Felldin M.; Foss A.; Kyllonen L.; Langstrom B.; Nilsson B.; Korsgren O.; Lundgren T. Positron emission tomography in clinical islet transplantation. Am. J. Transplant. 9(12):2816-2824; 2009.
15. Faradji R. N.; Froud T.; Messinger S.; Monroy K.; Pileggi A.; Mineo D.; Tharavanij T.; Mendez A. J.; Ricordi C.; Alejandro R. Long-term metabolic and hormonal effects of exenatide on islet transplant recipients with allograft dysfunction. Cell Transplant. 18:1247-1259; 2009.
16. Froud T.; Baidal D. A.; Faradji R.; Cure P.; Mineo D.; Selvaggi G.; Kenyon N. S.; Ricordi C.; Alejandro R. Islet transplantation with alemtuzumab induction and calcineurin-free maintenance immunosuppression results in improved short- and long-term outcomes. Transplantation 86:1695-1701; 2008.
17. Gangemi A.; Salehi P.; Hatipoglu B.; Martellotto J.; Barbaro B.; Kuechle J. B.; Qi M.; Wang Y.; Pallan P.; Owens C.; Bui J.; West D.; Kaplan B.; Benedetti E.; Oberholzer J. Islet transplantation for brittle type 1 diabetes: The UIC protocol. Am. J. Transplant. 8:1250-1261; 2008.
18. Han D.; Berman D. M.; Willman M.; Buchwald P.; Rothen D.; Kenyon N. M.; Kenyon N. S. Choice of immunosuppression influences cytomegalovirus DNAemia in cynomolgus monkey (Macaca fascicularis) islet allograft recipients. Cell Transplant. 19(12):1547-1561; 2010.
19. Han D.; Xu X.; Baidal D.; Leith J.; Ricordi C.; Alejandro R.; Kenyon N. S. Assessment of cytotoxic lymphocyte gene expression in the peripheral blood of human islet allograft recipients. Elevation precedes clinical evidence of rejection. Diabetes 53:2281-2290; 2004.
20. Hricik D. E.; Rodriguez V.; Riley J.; Bryan K.; Tary-Lehmann M.; Greenspan N.; Dejelo C.; Schulak J. A.; Heeger P. S. Enzyme linked immunosorbent spot (ELISPOT) assay for interferon-gamma independently predicts renal function in kidney transplant recipients. Am. J. Transplant. 3:878-884; 2003.
21. Huurman V. A.; Hilbrands R.; Pinkse G. G.; Gillard P.; Duinkerken G.; van de Linde P.; van der Meer-Prins P. M.; Versteeg-van der Voort Maarschalk M.F., Verbeeck K.; Alizadeh B. Z.; Mathieu C.; Gorus F. K.; Roelen D. L.; Claas F. H.; Keymeulen B.; Pipeleers D. G.; Roep B. O. Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation. PLoS ONE 3:e2435; 2008.
22. Huurman V. A.; Velthuis J. H.; Hilbrands R.; Tree T. I.; Gillard P.; van der Meer-Prins P. M.; Duinkerken G.; Pinkse G. G.; Keymeulen B.; Roelen D. L.; Claas F. H.; Pipeleers D. G.; Roep B. O. Allograft-specific cytokine profiles associate with clinical outcome after islet cell transplantation. Am. J. Transplant. 9:382-388; 2009.
23. Jain R.; Tartar D. M.; Gregg R. K.; Divekar R. D.; Bell J. J.; Lee H. H.; Yu P.; Ellis J. S.; Hoeman C. M.; Franklin C. L.; Zaghouani H. Innocuous IFNgamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production. J. Exp. Med. 205:207-218; 2008.
24. Luo B.; Chan W. F.; Lord S. J.; Nanji S. A.; Rajotte R. V.; Shapiro A. M.; Anderson C. C. Diabetes induces rapid suppression of adaptive immunity followed by homeostatic T-cell proliferation. Scand. J. Immunol. 65:22-31; 2007.
25. Mallone R.; Martinuzzi E.; Blancou P.; Novelli G.; Afonso G.; Dolz M.; Bruno G.; Chaillous L.; Chatenoud L.; Bach J. M.; van Endert P. CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes. Diabetes 56:613-621; 2007.
26. Malosio M. L.; Esposito A.; Poletti A.; Chiaretti S.; Piemonti L.; Melzi R.; Nano R.; Tedoldi F.; Canu T.; Santambrogio P.; Brigatti C.; De Cobelli F.; Maffi P.; Secchi A.; Del Maschio A. Improving the procedure for detection of intrahepatic transplanted islets by magnetic resonance imaging. Am. J. Transplant. 9:2372-2382; 2009.
27. Najafian N.; Salama A. D.; Fedoseyeva E. V.; Benichou G.; Sayegh M. H. Enzyme-linked immunosorbent spot assay analysis of peripheral blood lymphocyte reactivity to donor HLA-DR peptides: Potential novel assay for prediction of outcomes for renal transplant recipients. J. Am. Soc. Nephrol. 13:252-259; 2002.
28. Nickel P.; Bestard O.; Volk H. D.; Reinke P. Diagnostic value of T-cell monitoring assays in kidney transplantation. Curr. Opin. Organ Transplant. 14:426-431; 2009.
29. Nickel P.; Presber F.; Bold G.; Biti D.; Schonemann C.; Tullius S. G.; Volk H. D.; Reinke P. Enzyme-linked immunosorbent spot assay for donor-reactive interferon-gamma-producing cells identifies T-cell presensitization and correlates with graft function at 6 and 12 months in renal-transplant recipients. Transplantation 78:1640-1646; 2004.
30. Posselt A.; Szot G.; Frassetto L. Islet allograft survival in type 1 diabetics using a calcineurin-free protocol based on efalizumab and sirolimus. Am. J. Transplant. 8:235; 2008.
31. Roep B. O.; Kallan A. A.; Duinkerken G.; Arden S. D.; Hutton J. C.; Bruining G. J.; de Vries R. R. T-cell reactivity to beta-cell membrane antigens associated with beta-cell destruction in IDDM. Diabetes 44:278-283; 1995.
32. Saini D.; Ramachandran S.; Nataraju A.; Benshoff N.; Liu W.; Desai N.; Chapman W.; Mohanakumar T. Activated effector and memory T cells contribute to circulating sCD30: Potential marker for islet allograft rejection. Am. J. Transplant. 8:1798-1808; 2008.
33. Toso C.; Edgar R.; Pawlick R.; Emamaullee J.; Merani S.; Dinyari P.; Mueller T. F.; Shapiro A. M.; Anderson C. C. Effect of different induction strategies on effector, regulatory and memory lymphocyte sub-populations in clinical islet transplantation. Transpl. Int. 22:182-191; 2009.
34. Toso C.; Isse K.; Demetris A. J.; Dinyari P.; Koh A.; Imes S.; Kin T.; Emamaullee J.; Senior P.; Shapiro A. M. Histologic graft assessment after clinical islet transplantation. Transplantation 88:1286-1293; 2009.
35. Toso C.; McCall M.; Emamaullee J.; Merani S.; Davis J.; Edgar R.; Pawlick R.; Kin T.; Knudsen L. B.; Shapiro A. M. Liraglutide, a long-acting human glucagon-like peptide 1 analogue, improves human islet survival in culture. Transpl. Int. 23:259-265; 2010.
36. Toso C.; Serre-Beinier V.; Emamaullee J.; Merani S.; Armanet M.; Wojtusciszyn A.; Bosco D.; Calandra T.; Roger T.; Morel P.; Shapiro A. M.; Berney T. The role of macrophage migration inhibitory factor in mouse islet transplantation. Transplantation 86:1361-1369; 2008.
37. Toso C.; Vallee J. P.; Morel P.; Ris F.; Demuylder-Mischler S.; Lepetit-Coiffe M.; Marangon N.; Saudek F.; Shapiro A. M.; Bosco D.; Berney T. Clinical magnetic resonance imaging of pancreatic islet grafts after iron nanoparticle labeling. Am. J. Transplant. 8:701-706; 2008.
38. Toso C.; Zaidi H.; Morel P.; Armanet M.; Andres A.; Pernin N.; Baertschiger R.; Slosman D.; Buhler L. H.; Bosco D.; Berney T. Positron-emission tomography imaging of early events after transplantation of islets of Langerhans. Transplantation 79:353-355; 2005.
39. Wu A. J.; Hua H.; Munson S. H.; Mc Devitt H. O. Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice. Proc. Natl. Acad. Sci. USA 99:12287-12292; 2002.