Effect of high product ratio massive transfusion on mortality in blunt and penetrating trauma patients

Journal of Trauma - Injury, Infection and Critical Care

Volumn 71, Issue 2 SUPPL. 3, 2011, Pages

  Rowell, Susan E ^a   Barbosa, Ronald ^a   Diggs, Brian S ^a   Schreiber, Martin ^a   The Trauma Outcomes Group, ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b NONE

Author keywords

Massive transfusion; Mechanism; Mortality; Trauma

Indexed keywords

ADULT; ARTICLE; BLOOD TRANSFUSION; BLUNT TRAUMA; EMERGENCY HEALTH SERVICE; ERYTHROCYTE; ERYTHROCYTE TRANSFUSION; HEART RATE; HUMAN; INJURY SCALE; INTERNATIONAL NORMALIZED RATIO; MAJOR CLINICAL STUDY; MORTALITY; MULTICENTER STUDY; PENETRATING TRAUMA; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SYSTOLIC BLOOD PRESSURE; THROMBOCYTE;

ADOLESCENT; ADULT; BLOOD COMPONENT TRANSFUSION; ERYTHROCYTE COUNT; FEMALE; HEMORRHAGE; HUMANS; MALE; MIDDLE AGED; PLATELET COUNT; RETROSPECTIVE STUDIES; SURVIVAL RATE; TRAUMA CENTERS; TREATMENT OUTCOME; WOUNDS, NONPENETRATING; WOUNDS, PENETRATING; YOUNG ADULT;

EID: 80051751322     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e318227ef53     Document Type: Article

References (28)

1. Borgman MA, Spinella PC, Perkins JG, et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusion at a combat support hospital. J Trauma. 2007;63:805-813. (Pubitemid 350287298)
2. Holcomb JB, Caruso J, McMullin NR, et al. Causes of death in Special Operations Forces on the modern battlefield: 2001-2006. Ann Surg. 2007;245:986-991. (Pubitemid 46809302)
3. Kelly JF, Ritenour AE, McLaughlin DF, et al. Injury severity and cause of death from Operation Iraqi Freedom and Operation Enduring Freedom: 2003-2004 versus 2006. J Trauma. 2008;64(2 suppl):S21-S26; discussion S26-S27.
4. Acosta JA, Yang JC, Winchel RJ, et al. Lethal injuries and time to death at a level 1 trauma center. J Am Coll Surg. 1998;186:528-533. (Pubitemid 28222075)
5. Sauaia A, Moore FA, Moore EE, et al. Epidemiology of trauma deaths: a reassessment. J Trauma. 1995;38:185-193.
6. American College of Surgeons. Advanced Trauma Life Support for Doctors. 2nd ed. Chicago, IL: American College of Surgeons; 1997.
7. Ledgerwood AM, Lucas CE. A review of studies on the effects of hemorrhagic shock and resuscitation on the coagulation profile. J Trauma. 2003;54:S68-S74. (Pubitemid 36758854)
8. British Committee for Standards in Haematolog; Stainsby D, MacLennan S, Thomas D, Isaac J, Hamilton PJ. Guidelines on the management of massive blood loss. Br J Haematol. 2006;135:634-641. (Pubitemid 44674073)
9. Hess JR, Holcomb JB, Hoyt DB. Damage control resuscitation: the need for specific blood products to treat the coagulopathy of trauma. Transfusion. 2006;46:685-686.
10. Holcomb JB, Jenkins D, Rhee P, et al. Damage control resuscitation: directly addressing the early coagulopathy of trauma. J Trauma. 2007;62:307-310.
11. Duchesne JC, Hunt JP, Wahl G, et al. Review of current blood transfusion strategies in a mature level 1 trauma center: were we wrong for the last 60 years? J Trauma. 2008;65:272-276; discussion 276-278.
12. Holcomb JB, Wade CE, Michalek JE, et al. Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients. Ann Surg. 2008;248:447-458.
13. Gunter OL Jr, Au BK, Isbell JM, Mowery NT, Young PP, Cotton BA. Optimizing outcomes in damage control resuscitation: identifying blood product ratios associated with improved survival. J Trauma. 2008;65:527-534.
14. Zink KA, Sambasivan CN, Holcomb JB, Chisholm G, Schreiber MA. A high ratio of plasma and platelets to packed red blood cells in the first 6 hours of massive transfusion improves outcomes in a large multicenter study. Am J Surg. 2009;197:565-570; discussion 570.
15. Dutton RP, Lefering R, Lynn M. Database predictors of transfusion and mortality. J Trauma. 2006;60:S70-S77. (Pubitemid 43898564)
16. Erickson ML, Champion MH, Ross RL, Ross RL, Neal ZM, Snyder EL. Management of blood shortages in a tertiary care academic medical center: the Yale-New Haven Hospital frozen blood reserve. Transfusion. 2008;48:2252-2263.
17. Hakala P, Lindahl J, Alberty A, Tanskanen P, Nieminen H, Porras M. Massive transfusion exceeding 150 units of packed red cells during the first 15 hours after injury. J Trauma. 1998;44:410-412. (Pubitemid 28124192)
18. Schmidt PJ. Blood and disaster-supply and demand. N Engl J Med. 2002;346:617-620.
19. Zimrin AB, Hess JR. Planning for pandemic influenza: effect of a pandemic on the supply and demand for blood products in the United States. Transfusion. 2007;47:1071-1079. (Pubitemid 46802078)
20. Hess JR, Zimrin AB. Massive blood transfusion for trauma. Curr Opin Hematol. 2005;12:488-492. (Pubitemid 41546481)
21. Gonzalez EA, Moore FA, Holcomb JB, et al. Fresh frozen plasma should be given earlier to patients requiring massive transfusion. J Trauma. 2007;62:112-119. (Pubitemid 46102840)
22. Malone DL, Hess JR, Fingerhut A. Massive transfusion practices around the globe and a suggestion for a common massive transfusion protocol. J Trauma. 2006;60:S91-S96.
23. Hunt JP, Weintraub SL, Wang YZ, Buechter KJ. Kinematics of trauma. In: Trauma. 5th ed. New York: McGraw-Hill Companies, Inc.; 2004.
24. Smith HP. Time to die from injuries received in road traffic accidents. Injury. 1970;2:99-102.
25. Malone DL, Dunne J, Tracy JK, Putnam AT, Scalea TM, Napolitano LM. Blood transfusion, independent of shock severity, is associated with worse outcome in trauma. J Trauma. 2003;54:898-905; discussion 905-907.
26. Demetriades D, Murray J, Charalambides K, et al. Trauma fatalities: time and location of hospital deaths. J Am Coll Surg. 2004;198:20-26. (Pubitemid 38201084)
27. Shaz BH, Dente CJ, Harris RS, MacLeod JB, Hillyer CD. Transfusion management of trauma patients. Anesth Analg. 2009;108:1760-1768.
28. Armand R, Hess JR. Treating coagulopathy in trauma patients. Transfus Med Rev. 2003;17:223-231. (Pubitemid 36900330)