Industry and regulatory experience of the glycosylation of monoclonal antibodies

Biotechnology and Applied Biochemistry

Volumn 58, Issue 4, 2011, Pages 213-219

  Read, Erik K ^a   Park, Jun T ^a   Brorson, Kurt A ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

glycosylation; monoclonal antibodies

Indexed keywords

ANALYTICAL METHOD; DATABASE ANALYSIS; DEGREE OF COMPLEXITY; EXPRESSION SYSTEM; FUNCTIONAL INFORMATION; GLYCANS; GLYCOFORMS; MARKETING APPLICATION;

ESTERIFICATION; GLYCOSYLATION; MONOCLONAL ANTIBODIES;

SURFACE PLASMON RESONANCE;

GLYCAN; HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; MONOCLONAL ANTIBODY; OLIGOSACCHARIDE;

ANALYTIC METHOD; CAPILLARY ELECTROPHORESIS; CARBOHYDRATE ANALYSIS; CELL TYPE; CHEMICAL MODIFICATION; CHO CELL; DATA BASE; GALACTOSYLATION; GENE EXPRESSION SYSTEM; GLYCOSYLATION; MASS SPECTROMETRY; MYELOMA CELL; NONHUMAN; OLIGOSACCHARIDE PROFILING; REVIEW;

ANIMALS; ANTIBODIES, MONOCLONAL; CHO CELLS; CRICETINAE; CRICETULUS; DATABASES, PROTEIN; DRUG APPROVAL; DRUG INDUSTRY; ELECTROPHORESIS, CAPILLARY; GLYCOSYLATION; HUMANS; LICENSURE; MASS SPECTROMETRY; OLIGOSACCHARIDES; POLYSACCHARIDES; QUALITY CONTROL; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 80051711268     PISSN: 08854513     EISSN: 14708744     Source Type: Journal    
DOI: 10.1002/bab.35     Document Type: Review

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