Biomarkers of exposure and effect-interpretation in human risk assessment

Air Quality, Atmosphere and Health

Volumn 4, Issue 3, 2011, Pages 161-167

  Sram, Radim J ^a   Binkova, Blanka ^a   Beskid, Olena ^a   Milcova, Alena ^a   Rossner, Pavel ^a   Rossner Jr , Pavel ^a   Rossnerova, Andrea ^a   Solansky, Ivo ^a   Topinka, Jan ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

Author keywords

Benzo a pyrene; Carcinogenic polycyclic aromatic hydrocarbons; Chromosomal aberrations; DNA adducts; Personal monitoring

Indexed keywords

ADSORPTION; BIOMARKER; CARCINOGEN; CHROMOSOME; CYTOGENETICS; ENVIRONMENTAL IMPACT; GENETIC ANALYSIS; HEALTH MONITORING; HEALTH RISK; MITOCHONDRIAL DNA; OCCUPATIONAL EXPOSURE; PAH; PARTICLE SIZE; PUBLIC HEALTH; RISK ASSESSMENT; SAMPLER; TRANSLOCATION; URBAN POLLUTION;

CZECH REPUBLIC; PRAGUE;

EID: 80051694260     PISSN: 18739318     EISSN: 18739326     Source Type: Journal    
DOI: 10.1007/s11869-011-0133-8     Document Type: Article

References (17)

1. Binkova B, Smerhovsky Z, Strejc P, Boubelik O, Stavkova Z, Chvatalova I, Sram RJ (2002) DNA-adducts and atherosclerosis: a study of accidental and sudden death males in the Czech Republic. Mutat Res 501: 115-128.
2. Binkova B, Chvatalova I, Lnenickova Z, Milcova A, Tulupova E, Farmer PB, Sram RJ (2007a) a) PAH-DNA adducts in environmentally exposed population in relation to metabolic and DNA repair gene polymorphisms. Mutat Res 620: 49-61.
3. Binkova B, Topinka J, Sram RJ, Sevastyanova O, Novakova Z, Schmuczerova J, Kalina I, Popov T, Farmer PB (2007b) b) In vitro genotoxicity of PAH mixtures and organic extract from urban air particles part I: acellular assay. Mutat Res 620: 114-122.
4. Bonassi S, Norppa H, Ceppi M, Stromberg U, Vermuelen R, Znaor A, Cebulska-Wasilevska A, Fabianova E, Fucic A, Gundy S, Hansteen IL, Knudsen LE, Lazutka J, Rossner P, Sram RJ, Boffetta P (2008) Chromosomal aberration frequency in lymphocytes predicts the risk of cancer: results from a pooled cohort study of 22 358 subjects in 11 countries. Carconogenesis 29: 1178-1183.
5. Gammon MD, Sagiv SK, Eng SM, Shantakumar S, Gaudet MM, Teitelbaum SL, Britton JA, Terry MB, Wang LW, Wang Q, Stellman SD, Beyea J, Hatch M, Kabat GC, Wolff MS, Levin B, Neugut AI, Santella RM (2004) Polycyclic aromatic hydrocarbon-DNA adducts and breast cancer: a pooled analysis. Arch Environ Health 59: 640-649.
6. Lewtas J (2007) Air pollution combustion emissions: characterization of causative agents and mechanisms associated with cancer, reproductive, and cardiovascular effects. Mutat Res 636: 95-133.
7. Lucas J N, Sachs RK (1993) Using 3-colour chromosome painting to decide between chromosome aberration models. Proc Natl AcadSci USA 90: 1484-1487.
8. Phillips DH (2005) DNA adducts as markers of exposure and risk. Mutat Res 577: 384-392.
9. Rossner P Jr, Svecova V, Milcova A, Lnenickova Z, Solansky I, Sram RJ (2008) Seasonal variability of oxidative stress markers in city bus drivers. Part I. Oxidative damage to DNA. Mutat Res 642: 14-20.
10. Rubes J, Kucharova S, Vozdova M, Musilova P, Zudova Z (1998) Cytogenetic analysis of peripheral lymphocytes in medical personnel by means of FISH. Mutat Res 412: 293-298.
11. Sigurdson AJ, Ha M, Hauptmann M, Bhatti P, Sram RJ, Beskid O, Tawn EJ, Whitehouse CA, Lindholm C, Nakano M, Kodama Y, Nakamura N, Vorobtsova I, Oestreicher U, Staphan G, Yong LC, Bauchinger M, Schmid E, Chung HM, Darroudi F, Roy L, Voisin P, Barquinero JF, Livingston G, Blakey D, Hayata I, Zhang W, Wang C, Benett LM, Littlefield LG, Edwards AA, Kleinerman RA, Tucker JD (2008) International study of factors affecting human chromosome translocations. Mutat Res 652: 112-121.
12. Sram RJ, Beskid O, Binkova B, Chvatalova I, Lnenickova Z, Milcova A, Solansky I, Tulupova E, Bavorova H, Ocadlikova D, Farmer PB (2007a) Chromosomal aberrations in environmentally exposed population in relation to metabolic and DNA repair genes polymorphisms. Mutat Res 620: 22-33.
13. Sram RJ, Beskid O, Rössnerova A, Rössner P, Lnenickova Z, Milcova A, Solansky I, Binkova B (2007b) Environmental exposure to carcinogenic polycyclic aromatic hydrocarbons-the interpretation of cytogenetic analysis by FISH. Toxicol Lett 172: 12-20.
14. Topinka J, Sevastyanova O, Binkova B, Chvatalova I, Milcova A, Lnenickova Z, Novakova Z, Solansky I, Sram RJ (2007) Biomarkers of air pollution exposure-a study of policemen in Prague. Mutat Res 624: 9-17.
15. Tucker JD, Morgan WF, Awa AA, Bauchinger M, Blakei D, Cornforc MN, Littlefield LG, Natarajan AT, Shasserre C (1995) A proposed system for scoring structural aberrations detected by chromosome painting. Cytogenet Cell Genet 68: 211-221.
16. Tucker JD, Moore DH 2nd, Ramsey MJ, Kato P, Langlois RG, Burroughs B, Long L, Garry VF (2003) Multi-endpoint biological monitoring of phosphine workers. Mutat Res 536: 7-14.
17. Verdorfer I, Neubauer S, Letzer S, Angerer J, Arutyunyan R, Martus P, Wucherer M, Gebhart E (2001) Chromosome painting for cytogenetic monitoring of occupationally exposed and non-exposed groups of human individuals. Mutat Res 491: 97-109.