Sulforaphane induces apoptosis in human hepatic cancer cells through inhibition of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase4, mediated by hypoxia inducible factor-1-dependent pathway

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1814, Issue 10, 2011, Pages 1340-1348

  Jeon, Young Keul ^a   Yoo, Dong Ryeol ^a   Jang, Yun Ho ^a   Jang, Se Young ^a   Nam, Myeong Jin ^a  

^a Gachon University College of Medicine   (South Korea)

Author keywords

6 Phosphofructo 2 kinase fructose 2,6 biphosphatases; Hypoxia inducible factor 1; Mitogen activated protein kinase; Proteomic analysis; Sulforaphane

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE; FRUCTOSE 2,6 BISPHOSPHATASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; SULFORAPHANE;

AMINO ACID SEQUENCE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; TWO DIMENSIONAL ELECTROPHORESIS;

ANTICARCINOGENIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIVER NEOPLASMS; MODELS, BIOLOGICAL; PHOSPHOFRUCTOKINASE-2; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THIOCYANATES; TUMOR CELLS, CULTURED;

EID: 80051665521     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2011.05.015     Document Type: Article

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