Predictions in the face of clinical reality: HistoCheck versus high-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease

Biology of Blood and Marrow Transplantation

Volumn 17, Issue 9, 2011, Pages 1409-1415

  Askar, Medhat ^a   Sobecks, Ronald ^b   Morishima, Yasuo ^c   Kawase, Takakazu ^c   Nowacki, Amy ^a   Makishima, Hideki ^a   Maciejewski, Jaroslaw ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b TAUSSIG CANCER INSTITUTE   (United States)

^c AICHI CANCER CENTER HOSPITAL   (Japan)

Author keywords

HistoCheck; HLA; HSCT; Mismatched; Unrelated donor

Indexed keywords

ACUTE GRAFT VERSUS HOST DISEASE; ALGORITHM; ALLELE; ARTICLE; COMPUTER PROGRAM; DISEASE SEVERITY; DONOR SELECTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HLA MATCHING; HLA SYSTEM; HUMAN; INTERNET; PREDICTION; SCORING SYSTEM;

ACUTE DISEASE; ALGORITHMS; ALLELES; AMINO ACID SEQUENCE; GRAFT VS HOST DISEASE; HISTOCOMPATIBILITY; HLA ANTIGENS; HUMANS; PREDICTIVE VALUE OF TESTS; SEVERITY OF ILLNESS INDEX;

EID: 80051664480     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2011.01.015     Document Type: Article

References (21)

1. Petersdorf E.W., Anasetti C., Martin P.J., et al. Limits of HLA mismatching in unrelated hematopoietic cell transplantation. Blood 2004, 104:2976-2980.
2. Morishima Y., Sasazuki T., Inoko H., et al. The clinical significance of human leukocyte antigen (HLA) allele compatibility in patients receiving a marrow transplant from serologically HLA-A, HLA-B, and HLA-DR matched unrelated donors. Blood 2002, 99:4200-4206.
3. Flomenberg N., Baxter-Lowe L.A., Confer D., et al. Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome. Blood 2004, 104:1923-1930.
4. Ludajic K., Balavarca Y., Bickeboller H., et al. Impact of HLA-DPB1 allelic and single amino acid mismatches on HSCT. Br J Haematol 2008, 142:436-443.
5. Kawase T., Matsuo K., Kashiwase K., et al. HLA mismatch combinations associated with decreased risk of relapse: implications for the molecular mechanism. Blood 2009, 113:2851-2858.
6. Crocchiolo R., Zino E., Vago L., et al. Nonpermissive HLA-DPB1 disparity is a significant independent risk factor for mortality after unrelated hematopoietic stem cell transplantation. Blood 2009, 114:1437-1444.
7. Bray R.A., Hurley C.K., Kamani N.R., et al. National marrow donor program HLA matching guidelines for unrelated adult donor hematopoietic cell transplants. Biol Blood Marrow Transplant 2008, 14:45-53.
8. Elsner H.A., DeLuca D., Strub J., Blasczyk R. HistoCheck: rating of HLA class I and II mismatches by an internet-based software tool. Bone Marrow Transplant 2004, 33:165-169.
9. Elsner H.A., Blasczyk R. Sequence similarity matching: proposal of a structure-based rating system for bone marrow transplantation. Eur J Immunogenet 2002, 29:229-236.
10. Shaw B.E., Barber L.D., Madrigal J.A., Cleaver S., Marsh S.G. Scoring for HLA matching? A clinical test of HistoCheck. Bone Marrow Transplant 2004, 34:367-368. author reply 369.
11. Heemskerk M.B., Doxiadis, Roelen D.L., Claas F.H., Oudshoorn M. The HistoCheck algorithm does not predict T-cell alloreactivity in vitro. Bone Marrow Transplant 2005, 36:927-928.
12. Kawase T., Morishima Y., Matsuo K., et al. High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism. Blood 2007, 110:2235-2241.
13. Lee S.J., Klein J., Haagenson M., et al. High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation. Blood 2007, 110:4576-4583.
14. Heemskerk M.B., Roelen D.L., Dankers M.K., et al. Allogeneic MHC class I molecules with numerous sequence differences do not elicit a CTL response. Hum Immunol 2005, 66:969-976.
15. Heemskerk M.B., Cornelissen J.J., Roelen D.L., et al. Highly diverged MHC class I mismatches are acceptable for haematopoietic stem cell transplantation. Bone Marrow Transplant 2007, 40:193-200.
16. Morishima Y., Kawase T., Malkki M., Petersdorf E.W. Effect of HLA-A2 allele disparity on clinical outcome in hematopoietic cell transplantation from unrelated donors. Tissue Antigens 2007, 69(Suppl 1):31-35.
17. Rodey G.E., Fuller T.C. Public epitopes and the antigenic structure of the HLA molecules. Crit Rev Immunol 1987, 7:229-267.
18. Duquesnoy R.J., Marrari M. HLAMatchmaker: a molecularly based algorithm for histocompatibility determination. II. Verification of the algorithm and determination of the relative immunogenicity of amino acid triplet-defined epitopes. Hum Immunol 2002, 63:353-363.
19. Duquesnoy R.J., Askar M. HLAMatchmaker: a molecularly based algorithm for histocompatibility determination. V. Eplet matching for HLA-DR, HLA-DQ, and HLA-DP. Hum Immunol 2007, 68:12-25.
20. Wade J.A., Hurley C.K., Takemoto S.K., et al. HLA mismatching within or outside of cross-reactive groups (CREGs) is associated with similar outcomes after unrelated hematopoietic stem cell transplantation. Blood 2007, 109:4064-4070.
21. Duquesnoy R., Spellman S., Haagenson M., Wang T., Horowitz M.M., Oudshoorn M. HLAMatchmaker-defined triplet matching is not associated with better survival rates of patients with class I HLA allele mismatched hematopoietic cell transplants from unrelated donors. Biol Blood Marrow Transplant 2008, 14:1064-1071.