Metabolically engineered Escherichia coli for biotechnological production of four-carbon 1,4-dicarboxylic acids

Journal of Industrial Microbiology and Biotechnology

Volumn 38, Issue 6, 2011, Pages 649-656

  Cao, Yujin ^a   Cao, Yugang ^b   Lin, Xiangzhi ^a  

^a Key Laboratory of Marine Genetic Resources of Fujian Province   (China)

^b CHINA UNIVERSITY OF PETROLEUM   (China)

Author keywords

Biotechnological production; Escherichia coli; Four carbon 1,4 dicarboxylic acids; Metabolic engineering

Indexed keywords

ASPARTIC ACID; DICARBOXYLIC ACID; FOUR CARBON 1,4 DICARBOXYLIC ACID; FUMARIC ACID; MALIC ACID; OXALOACETIC ACID; SUCCINIC ACID; UNCLASSIFIED DRUG;

BIOCATALYSIS; BIOENERGY; BIOTECHNOLOGY; CHEMICAL STRUCTURE; DNA MODIFICATION; ENERGY METABOLISM; ESCHERICHIA COLI; METABOLIC ENGINEERING; NONHUMAN; REVIEW; SYNTHESIS;

BIOMASS; CARBON; DICARBOXYLIC ACIDS; ESCHERICHIA COLI; GENETIC ENGINEERING; INDUSTRIAL MICROBIOLOGY; MALATES; METABOLIC NETWORKS AND PATHWAYS; SUCCINIC ACID;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 80051664276     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-010-0913-4     Document Type: Review

References (67)

1. Abbott DA, Zelle RM, Pronk JT, van Maris AJA (2009) Metabolic engineering of Saccharomyces cerevisiae for production of carboxylic acids: current status and challenges. FEMS Yeast Res 9:1123-1136
2. Ager DJ, Pantaleone DP, Henderson SA, Katritzky AR, Prakash I, Walters DE (1998) Commercial, synthetic nonnutritive sweeteners. Angew Chem Int Edit 37:1802-1817
3. Arikawa Y, Kuroyanagi T, Shimosaka M, Muratsubaki H, Enomoto K, Kodaira R, Okazaki M (1999) Effect of gene disruptions of the TCA cycle on production of succinic acid in Saccharomyces cerevisiae. J Biosci Bioeng 87:28-36 (Pubitemid 29162227)
4. Bailey JE (1991) Toward a science of metabolic engineering. Science 252:1668-1675 (Pubitemid 21917084)
5. Beauprez JJ, De Mey M, Soetaert WK (2010) Microbial succinic acid production: natural versus metabolic engineered producers. Process Biochem 45:1103-1114
6. Berovi M (1999) Scale-up of citric acid fermentation by redox potential control. Biotechnol Bioeng 64:552-557
7. Bunch PK, Mat-Jan F, Lee N, Clark DP (1997) The IdhA gene encoding the fermentative lactate dehydrogenase of Escherichia coli. Microbiology 143:187-195 (Pubitemid 27072974)
8. Cao Y, Yang J, Xian M, Xu X, Liu W (2010) Increasing unsaturated fatty acid contents in Escherichia coli by coexpression of three different genes. Appl Microbiol Biotechnol 87:271-280
9. Causey TB, Shanmugam KT, Yomano LP, Ingram LO (2004) Engineering Escherichia coli for efficient conversion of glucose to pyruvate. Proc Natl Acad Sci U S A 101:2235-2240 (Pubitemid 38269295)
10. Chao YP, Patnaik R, Roof WD, Young RF, Liao JC (1993) Control of gluconeogenic growth by pps and pck in Escherichia coli. J Bacteriol 175:6939-6944 (Pubitemid 23322445)
11. Chatterjee R, Millard CS, Champion K, Clark DP, Donnelly MI (2001) Mutation of the ptsG gene results in increased production of succinate in fermentation of glucose by Escherichia coli. Appl Environ Microbiol 67:148-154 (Pubitemid 32044412)
12. Clark DP (1989) The fermentation pathways of Escherichia coli. FEMS Microbiol Lett 63:223-234
13. De Mey M, De Maeseneire S, Soetaert W, Vandamme E (2007) Minimizing acetate formation in E. coli fermentations. J Ind Microbiol Biotechnol 34:689-700 (Pubitemid 47622241)
14. der Werf MJV, Guettler MV, Jain MK, Zeikus JG (1997) Environmental and physiological factors affecting the succinate product ratio during carbohydrate fermentation by Actinobacillus sp. 130Z. Arch Microbiol 167:332-342 (Pubitemid 27245210)
15. Förster A, Jacobs K, Juretzek T, Mauersberger S, Barth G (2007) Overexpression of the ICL1 gene changes the product ratio of citric acid production by Yarrowia lipolytica. Appl Microbiol Biotechnol 77:861-869 (Pubitemid 350159857)
16. Gokarn RR, Eiteman MA, Altman E (1998) Expression of pyruvate carboxylase enhances succinate production in Escherichia coli without affecting glucose uptake. Biotechnol Lett 20:795-798 (Pubitemid 28479223)
17. Gokarn RR, Evans JD, Walker JR, Martin SA, Eiteman MA, Altman E (2001) The physiological effects and metabolic alterations caused by the expression of Rhizobium etli pyruvate carboxylase in Escherichia coli. Appl Microbiol Biotechnol 56:188-195 (Pubitemid 32661555)
18. Goldberg I, Lonberg-Holm K, Bagley EA, Stieglitz B (1983) Improved conversion of fumarate to succinate by Escherichia coli strains amplified for fumarate reductase. Appl Environ Microbiol 45:1838-1847 (Pubitemid 13027698)
19. Henry CS, Jankowski MD, Broadbelt LJ, Hatzimanikatis V (2006) Genome-scale thermodynamic analysis of Escherichia coli metabolism. Biophys J 90:1453-1461
20. Hong S (2007) Systems approaches to succinic acid-producing microorganisms. Biotechnol Bioprocess Eng 12:73-79 (Pubitemid 46730838)
21. Hong SH, Lee SY (2004) Enhanced production of succinic acid by metabolically engineered Escherichia coli with amplified activities of malic enzyme and fumarase. Biotechnol Bioprocess Eng 9:252-255
22. Hong SH, Lee SY (2002) Importance of redox balance on the production of succinic acid by metabolically engineered Escherichia coli. Appl Microbiol Biotechnol 58:286-290 (Pubitemid 34185570)
23. Janausch IG, Zientz E, Tran QH, Kroger A, Unden G (2002) C4-dicarboxylate carriers and sensors in bacteria. Biochim Biophys Acta 1553:39-56
24. Jankowski MD, Henry CS, Broadbelt LJ, Hatzimanikatis V (2008) Group contribution method for thermodynamic analysis of complex metabolic networks. Biophys J 95:1487-1499
25. Jiang L, Althoff EA, Clemente FR, Doyle L, Rothlisberger D, Zanghellini A, Gallaher JL, Betker JL, Tanaka F, Barbas CF III, Hilvert D, Houk KN, Stoddard BL, Baker D (2008) De novo computational design of retro-aldol enzymes. Science 319:1387-1391 (Pubitemid 351354873)
26. Kawabata N, Hatanaka H, Odaka H (1995) Continuous production of L-aspartic acid from ammonium fumarate using immobilized cells by capture on the surface of nonwoven cloth coated with a pyridinium-type polymer. J Ferment Bioeng 79:317-322
27. Keseler IM, Collado-Vides J, Gama-Castro S, Ingraham J, Paley S, Paulsen IT, Peralta-Gil M, Karp PD (2005) EcoCyc: a comprehensive database resource for Escherichia coli. Nucleic Acids Res 33:D334-D337 (Pubitemid 40207890)
28. Kim P, Laivenieks M, Vieille C, Zeikus JG (2004) Effect of overexpression of Actinobacillus succinogenes phosphoenolpyruvate carboxykinase on succinate production in Escherichia coli. Appl Environ Microbiol 70:1238-1241 (Pubitemid 38568256)
29. Kornberg H (1966) The role and control of the glyoxylate cycle in Escherichia coli. Biochem J 99:1-11
30. Kotrba P, Inui M, Yukawa H (2001) Bacterial phosphotransferase system (PTS) in carbohydrate uptake and control of carbon metabolism. J Biosci Bioeng 92:502-517 (Pubitemid 34107168)
31. Kwon Y-D, Kwon O-H, Lee H-S, Kim P (2007) The effect of NADP-dependent malic enzyme expression and anaerobic C4 metabolism in Escherichia coli compared with other anaplerotic enzymes. J Appl Microbiol 103:2340-2345 (Pubitemid 350191180)
32. Lee SJ, Lee D-Y, Kim TY, Kim BH, Lee J, Lee SY (2005) Metabolic engineering of Escherichia coli for enhanced production of succinic acid, based on genome comparison and in silico gene knockout simulation. Appl Environ Microbiol 71:7880-7887 (Pubitemid 41805090)
33. Liao JC, Hou S-Y, Chao Y-P (1996) Pathway analysis, engineering, and physiological considerations for redirecting central metabolism. Biotechnol Bioeng 52:129-140 (Pubitemid 26317947)
34. Lin H, Bennett GN, San K-Y (2005) Effect of carbon sources differing in oxidation state and transport route on succinate production in metabolically engineered Escherichia coli. J Ind Microbiol Biotechnol 32:87-93 (Pubitemid 40575675)
35. Lin H, Bennett GN, San K-Y (2005) Fed-batch culture of a metabolically engineered Escherichia coli strain designed for high-level succinate production and yield under aerobic conditions. Biotechnol Bioeng 90:775-779 (Pubitemid 40744245)
36. Lin H, Bennett GN, San K-Y (2005) Genetic reconstruction of the aerobic central metabolism in Escherichia coli for the absolute aerobic production of succinate. Biotechnol Bioeng 89:148-156
37. Lin H, Bennett GN, San K-Y (2005) Metabolic engineering of aerobic succinate production systems in Escherichia coli to improve process productivity and achieve the maximum theoretical succinate yield. Metab Eng 7:116-127 (Pubitemid 40392480)
38. Lu S, Eiteman M, Altman E (2009) pH and base counterion affect succinate production in dual-phase Escherichia coli fermentations. J Ind Microbiol Biotechnol 36:1101-1109
39. 2 on succinate production in dual-phase Escherichia coli fermentations. J Biotechnol 143:213-223
40. Mat-Jan F, Alam KY, Clark DP (1989) Mutants of Escherichia coli deficient in the fermentative lactate dehydrogenase. J Bacteriol 171:342-348
41. Mavrovouniotis ML (1990) Group contributions for estimating standard gibbs energies of formation of biochemical compounds in aqueous solution. Biotechnol Bioeng 36:1070-1082
42. Millard C, Chao Y, Liao J, Donnelly M (1996) Enhanced production of succinic acid by overexpression of phosphoenolpyruvate carboxylase in Escherichia coli. Appl Environ Microbiol 62:1808-1810 (Pubitemid 26143465)
43. Moon SY, Hong SH, Kim TY, Lee SY (2008) Metabolic engineering of Escherichia coli for the production of malic acid. Biochem Eng J 40:312-320 (Pubitemid 351711621)
44. Murai T, Tokushige M, Nagai J, Katsuki H (1971) Physiological functions of NAD-and NADP-linked malic enzymes in Escherichia coli. Biochem Biophys Res Commun 43:875-881
45. Negre D, Cortay JC, Old IG, Galinier A, Richaud C, Saintgirons I, Cozzone AJ (1991) Overproduction and characterization of the iclR gene product of Escherichia coli K-12 and comparison with that of Salmonella typhimurium LT2. Gene 97:29-37
46. Park JH, Lee SY (2010) Metabolic pathways and fermentative production of L-aspartate family amino acids. Biotechnol J 5:560-577
47. Roa Engel C, Straathof A, Zijlmans T, van Gulik W, van der Wielen L (2008) Fumaric acid production by fermentation. Appl Microbiol Biotechnol 78:379-389
48. Sánchez AM, Bennett GN, San K-Y (2006) Batch culture characterization and metabolic flux analysis of succinate-producing Escherichia coli strains. Metab Eng 8:209-226 (Pubitemid 44382420)
49. Sanwal BD (1970) Regulatory characteristics of the diphosphopyridine nucleotide-specific malic enzyme of Escherichia coli. J Biol Chem 245:1212-1216
50. Sauer U, Eikmanns BJ (2005) The PEP-pyruvate-oxaloacetate node as the switch point for carbon flux distribution in bacteria. FEMS Microbiol Rev 29:765-794 (Pubitemid 41149049)
51. Schmid A, Dordick JS, Hauer B, Kiener A, Wubbolts M, Witholt B (2001) Industrial biocatalysis today and tomorrow. Nature 409:258-268 (Pubitemid 32144296)
52. Seko H, Takeuchi S, Yajima K, Senuma M, Tosa T (1990) L-Aspartic acid production using immobilized E. coli cells in a packed-bed reactor. Ann N Y Acad Sci 589:540-552
53. Stokes JL (1949) Fermentation of glucose by suspensions of Escherichia coli. J Bacteriol 57:147-158
54. Stols L, Donnelly M (1997) Production of succinic acid through overexpression of NAD (+)-dependent malic enzyme in an Escherichia coli mutant. Appl Environ Microbiol 63:2695-2701 (Pubitemid 27292862)
55. Tarmy EM, Kaplan NO (1968) Chemical characterization of D-lactate dehydrogenase from Escherichia coli B. J Biol Chem 243:2579-2586
56. Tsao G, Cao N, Du J, Gong C (1999) Production of multifunctional organic acids from renewable resources. In: Tsao G, Brainard A, Bungay H, Cao N, Cen P, Chen Z, Du J, Foody B, Gong C, Hall P, Ho N, Irwin D, Iyer P, Jeffries T, Ladisch C, Ladisch M, Lee Y, Mosier N, Mühlemann H, Sedlak M, Shi N, Tolan J, Torget R, Wilson D, Xia L (eds) Recent progress in bioconversion of lignocellulosics. Springer, Berlin/Heidelberg, pp 243-280
57. Vemuri GN, Eiteman MA, Altman E (2002) Effects of growth mode and pyruvate carboxylase on succinic acid production by metabolically engineered strains of Escherichia coli. Appl Environ Microbiol 68:1715-1727 (Pubitemid 34284775)
58. Vemuri GN, Eiteman MA, Altman E (2002) Succinate production in dual-phase Escherichia coli fermentations depends on the time of transition from aerobic to anaerobic conditions. J Ind Microbiol Biotechnol 28:325-332 (Pubitemid 34759913)
59. Wang X, Gong C, Tsao G (1998) Bioconversion of fumaric acid to succinic acid by recombinant E. coli. Appl Biochem Biotechnol 70-72:919-928 (Pubitemid 28361111)
60. Wendisch VF, Bott M, Eikmanns BJ (2006) Metabolic engineering of Escherichia coli and Corynebacterium glutamicum for biotechnological production of organic acids and amino acids. Curr Opin Microbiol 9:268-274 (Pubitemid 44183577)
61. Werpy T, Petersen G (eds) (2004) Top value added chemicals from biomass, vol I. US Department of Energy, Oak Ridge, pp 1-76
62. Yan Y, Liao J (2009) Engineering metabolic systems for production of advanced fuels. J Ind Microbiol Biotechnol 36:471-479
63. Zeikus JG, Jain MK, Elankovan P (1999) Biotechnology of succinic acid production and markets for derived industrial products. Appl Microbiol Biotechnol 51:545-552 (Pubitemid 29266304)
64. Zhang D, Liang N, Shi Z, Liu L, Chen J, Du G (2009) Enhancement of α-ketoglutarate production in Torulopsis glabrata: Redistribution of carbon flux from pyruvate to α-ketoglutarate. Biotechnol Bioprocess Eng 14:134-139
65. Zhang X, Jantama K, Moore JC, Jarboe LR, Shanmugam KT, Ingram LO (2009) Metabolic evolution of energy-conserving pathways for succinate production in Escherichia coli. Proc Natl Acad Sci 106:20180-20185
66. Zhu J, Shimizu K (2004) The effect of pfl gene knockout on the metabolism for optically pure D-lactate production by Escherichia coli. Appl Microbiol Biotechnol 64:367-375 (Pubitemid 38626461)
67. Zhu Y, Eiteman M, Lee S, Altman E (2010) Conversion of glycerol to pyruvate by Escherichia coli using acetate-and acetate/glucose-limited fed-batch processes. J Ind Microbiol Biotechnol 37:307-312