Activation of the Wnt/Beta-catenin signaling pathway during oral carcinogenesis process is not influenced by the absence of galectin-3 in mice

Anticancer Research

Volumn 31, Issue 9, 2011, Pages 2805-2811

  Sant'Ana, Juliana Moreira De Almeida ^a   Chammas, Roger ^b   Liu, Fu Tong ^c   Nonogaki, Suely ^d   Cardoso, Sérgio Vitorino ^a   Loyola, Adriano Mota ^a   De Faria, Paulo Rogério ^a  

^a FEDERAL UNIVERSITY OF UBERLÂNDIA   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d INSTITUTO ADOLFO LUTZ   (Brazil)

Author keywords

Beta catenin; Immunohistochemistry; Mice; Oral carcinogenesis; Tongue

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; BETA CATENIN; GALECTIN 3; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER DIAGNOSIS; CARCINOGENESIS; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TONGUE CARCINOMA; TONGUE DISEASE;

ANIMALS; BETA CATENIN; CELL TRANSFORMATION, NEOPLASTIC; GALECTIN 3; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOUTH NEOPLASMS; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 80051646301     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. de Faria PR, Cardoso SV, Nishioka SA, Silva SJ and Loyola AM: Clinical presentation of patients with oral squamous cell carcinoma when first seen by dentists or physicians in a teaching hospital in Brazil. Clin Oral Investig 7: 46-51, 2003.
2. Minicucci EM, Ribeiro DA, da Silva GN, Pardini MI, Montovoni JC and Salvadori DM: The role of the TP53 gene during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. Exp Toxicol Pathol 63: 483-489, 2011.
3. Mognetti B, Di Carlo F and Berta GN: Animal models in oral cancer research. Oral Oncol 42: 448-460, 2006.
4. Liu FT and Rabinovich GA: Galectins as modulators of tumour progression. Nat Rev Cancer 5: 29-41, 2005.
5. Dumic J, Dabelic S and Flögel M: Galectin-3: An open-ended story. Biochim Biophys Acta 1760: 616-635, 2006.
6. Song S, Mazurek N, Liu C, Sun Y, Ding QQ, Liu K, Hung MC and Bresalier RS: Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity. Cancer Res 69: 1343-1349, 2009.
7. Honjo Y, Nangia-Makker P, Inohara H and Raz A: Down-regulation of galectin-3 suppresses tumorigenicity of human breast carcinoma cells. Clin Cancer Res 7: 661-668, 2000.
8. Abdel-Aziz HO, Murai Y, Takasaki I, Tabuchi Y, Zheng HC, Nomoto K, Takahashi H, Tsuneyama K, Kato I, Hsu DK, Liu FT, Hiraga K and Takano Y: Targeted disruption of the galectin-3 gene results in decreased susceptibility to NNK-induced lung tumorigenesis: an oligonucleotide microarray study. J Cancer Res Clin Oncol 134: 777-788, 2008.
9. Eude-Le Parco I, Gendronneau G, Dang T, Delacour D, Thyssen VL, Edelmann W, Peuchmaur M and Poirier F: Genetic assessment of the importance of galectin-3 in cancer initiation, progression, and dissemination in mice. Glycobiology 19: 68-75, 2009.
10. de Faria PR, Chammas R, de Melo TL, Hsu DK, Liu FT, Nonogaki S, Cardoso SV and Loyola AM: Absence of galectin-3 does not affect the development of experimental tongue carcinomas in mice. Exp Mol Pathol 90: 189-193, 2011.
11. Pećina-Slaus N: Wnt signal transduction pathway and apoptosis: a review. Cancer Cell Int 10: 22-26, 2010.
12. Shimura T, Takenaka Y, Tsutsumi S, Hogan V, Kikuchi A and Raz A: Galectin-3, a novel binding partner of β-catenin. Cancer Res 64: 6363-6367, 2004.
13. Hsu DK, Yang RY, Pan Z, Yu L, Salomon DR, Fung-Leung WP and Liu FT: Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses. Am J Pathol 156: 1073-1083, 2000.
14. Tang XH, Knudsen B, Bemis D, Tickoo S and Gudas LJ: Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice. Clin Cancer Res 10: 301-313, 2004.
15. Lumerman H, Freedman P and Kerpel S: Oral epithelial dysplasia and the development of invasive squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 79: 321-329, 1995.
16. Slootweg PJ and Eveson JW: Tumors of the hypopharynx, larynx and trachea. In: World Health Organization Classification of Tumors. Pathology and Genetics of Head and Neck Tumors. Barnes L, Eveson JW, Reichart P and Sidransky D (eds.). Lyon, I.A.R.C. Press., pp. 118-121, 2005.
17. Steidler NE and Reade PC: Initiation and promotion of experimental oral mucosa carcinogenesis in mice. J Oral Pathol 15: 43-47, 1986.
18. Fronza G, Campomenosi P, Iannone R and Abbondandolo A: The 4-nitroquinoline 1-oxide mutational spectrum in single stranded DNA is characterized by guanine to pyrimidine transversions. Nucleic Acids Res 20: 1283-1287, 1992.
19. Kandarkar SV, Sawant SS and Reade PC: Ultrastructural changes to the palatal mucosa of rats following the application of 4-nitroquinoline-1-oxide (4NQO) and vitamin C. Oral Oncol 34: 247-252, 1998.
20. Booth DR: A relationship found between intra-oral sites of 4NQO reductase activity and chemical carcinogenesis. Cell Tissue Kinet 23: 331-340, 1990.
21. Mirzayans R, Bashir S, Murray D and Paterson MC: Inverse correlation between p53 protein levels and DNA repair efficiency in human fibroblast strains treated with 4-nitroquinoline 1-oxide: evidence that lesions other than DNA strand breaks trigger the p53 response. Carcinogenesis 20: 941-946, 1999.
22. Kanojia D and Vaidya MM: 4-Nitroquinoline-1-oxide induced experimental carcinogenesis. Oral Oncol 42: 655-667, 2006.
23. Lo Muzio L, Staibano S, Pannone G, Grieco M, Mignogna MD, Cerrato A, Testa NF and De Rosa G: Beta- and gamma-catenin expression in oral squamous cell carcinomas. Anticancer Res 19: 3817-3826, 1999.
24. Xavier FC, Rodini CO, Ramalho LM, Mantesso A and Nunes FD: WNT-5A, but not matrix metalloproteinase 3 or beta-catenin protein, expression is related to early stages of lip carcinogenesis. J Oral Pathol Med 38: 708-715, 2009.
25. Paron I, Scaloni A, Pines A, Bachi A, Liu FT, Puppin C, Pandolfi M, Ledda L, Di Loreto C, Damante G and Tell G: Nuclear localization of galectin-3 in transformed thyroid cells: a role in transcriptional regulation. Biochem Biophys Res Commun 302: 545-553, 2003.
26. Weinberger PM, Adam BL, Gourin CG, Moretz WH 3rd, Bollag RJ, Wang BY, Liu Z, Lee JR and Terris DJ: Association of nuclear, cytoplasmic expression of galectin-3 with beta-catenin/Wnt-pathway activation in thyroid carcinoma. Arch Otolaryngol Head Neck Surg 133: 503-510, 2007.
27. Oka N, Nakahara S, Takenaka Y, Fukumori T, Hogan V, Kanayama HO, Yanagawa T and Raz A: Galectin-3 inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by activating AKT in human bladder carcinoma cells. Cancer Res 65: 7546-7553, 2005.