Closed traumatic brain injury model in sheep mimicking high-velocity, closed head trauma in humans

Zentralblatt fur Neurochirurgie

Volumn 72, Issue 3, 2011, Pages 120-126

  Grimmelt, A C ^a   Eitzen, S ^a   Balakhadze, I ^a   Fischer, B ^a   Wolfer J ^a   Schiffbauer, H ^a   Gorji, A ^a   Greiner, C ^b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b MarienHospital Osnabruck   (Germany)

Author keywords

closed traumatic brain injury; experimental animal model; magnetic resonance imaging; multiparametric cerebral monitoring; sheep

Indexed keywords

4 AMINOBUTYRIC ACID; ASPARTIC ACID; GLUTAMIC ACID; NEUROTRANSMITTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AXONAL INJURY; BRAIN TISSUE; CARBON DIOXIDE TENSION; CONTUSION; DISEASE SEVERITY; EXPERIMENTAL MODEL; HEAD INJURY; NERVE FIBER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGICAL ANATOMY; SHEEP; SKULL FRACTURE; SUBARACHNOID HEMORRHAGE; TRAUMATIC BRAIN INJURY; VELOCITY;

ANIMALS; ASPARTIC ACID; BRAIN; BRAIN INJURIES; CARBON DIOXIDE; DISEASE MODELS, ANIMAL; ELECTRON SPIN RESONANCE SPECTROSCOPY; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; HEAD INJURIES, CLOSED; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INTRACRANIAL PRESSURE; MAGNETIC RESONANCE IMAGING; OXYGEN CONSUMPTION; SHEEP; SHEEP, DOMESTIC;

EID: 80051638308     PISSN: 00444251     EISSN: 14389746     Source Type: Journal    
DOI: 10.1055/s-0031-1271732     Document Type: Article

References (36)

1. Stubbe HD, Greiner C, Van Aken H et al,. Cerebral vascular and metabolic response to sustained systemic inflammation in ovine traumatic brain injury. J Cereb Blood Flow Metab 2004 24 12 1400-1408 (Pubitemid 40019163)
2. Centers for Disease Control and Prevention, Department of Health and Human Services. Facts about Traumatic Brain Injury [Internet] CDC; USA. www.edc.gov 2006
3. Bullock MR, Lyeth BG, Muizelaar JP. Current status of neuroprotection trials for traumatic brain injury: lessons from animal models and clinical studies. Neurosurgery 1999 45 2 207-217 discussion 217220
4. Doppenberg EM, Choi SC, Bullock R. Clinical trials in traumatic brain injury: lessons for the future. J Neurosurg Anesthesiol 2004 16 1 87-94 (Pubitemid 38057407)
5. Gennarelli TA. Animate models of human head injury. J Neurotrauma 1994 11 4 357-368 (Pubitemid 24304688)
6. Cernak I. Animal models of head trauma. NeuroRx 2005 2 3 410-422 (Pubitemid 41444875)
7. Anderson RW, Brown CJ, Blumbergs PC et al,. Impact mechanics and axonal injury in a sheep model. J Neurotrauma 2003 20 10 961-974 (Pubitemid 37288556)
8. Zhang L, Yang KH, King AI. Biomechanics of neurotrauma. Neurol Res 2001 23 23 144-156 (Pubitemid 32290899)
9. Ommaya AK, Hirsch AE. Tolerances for cerebral concussion from head impact and whiplash in primates. J Biomech 1971 4 1 13-21
10. Ewing C, Thomas D, Lustick L et al,. The effect of the initial position of the head and neck to -Gx impact acceleration. In Proceedings 19th Stapp car crash conference, Nov. 1720, 1975 487-512
11. Gennarelli TA, Thibault LE, Adams JH et al,. Diffuse axonal injury and traumatic coma in the primate. Ann Neurol 1982 12 6 564-574 (Pubitemid 13250413)
12. Gennarelli TA. Head injury in man and experimental animals: clinical aspects. Acta Neurochir Suppl 1983 32 1-13
13. Finnie JW, Manavis J, Summersides GE et al,. Brain damage in pigs produced by impact with a non-penetrating captive bolt pistol. Aust Vet J 2003 81 3 159-164
14. Finnie JW, Blumbergs PC. Traumatic brain injury. Vet Pathol 2002 39 6 679-689
15. Gennarelli TA, Adams JH, Graham DI. Acceleration induced head injury in the monkey. I. The model, its mechanical and physiological correlates. Acta Neuropathol Suppl 1981 7 23-25
16. Adams JH, Graham DI, Gennarelli TA. Acceleration induced head injury in the monkey. II. Neuropathology. Acta Neuropathol Suppl 1981 7 26-28
17. Piper I. Intracranial Pressure and Elastance. In: Reilly P, Bullock R, editors Head Injury: Pathophysiology and Management of Severe Closed Head Injury London, Chapman & Hall 1997 101-120
18. Doppenberg EM, Zauner A, Watson JC et al,. Determination of the ischemic threshold for brain oxygen tension. Acta Neurochir Suppl 1998 71 166-169 (Pubitemid 128444387)
19. Zauner A, Clausen T, Alves OL et al,. Cerebral metabolism after fluid-percussion injury and hypoxia in a feline model. J Neurosurg 2002 97 3 643-649 (Pubitemid 34994382)
20. Menzel M, Rieger A, Roth S et al,. Comparison between continuous brain tissue pO2, pCO2, pH, and temperature and simultaneous cerebrovenous measurement using a multisensor probe in a porcine intracranial pressure model. J Neurotrauma 1998 15 4 265-276 (Pubitemid 28166578)
21. Nortje J, Gupta AK. The role of tissue oxygen monitoring in patients with acute brain injury. Br J Anaesth 2006 97 1 95-106
22. Clausen T, Khaldi A, Zauner A et al,. Cerebral acid-base homeostasis after severe traumatic brain injury. J Neurosurg 2005 103 4 597-607 (Pubitemid 43193865)
23. Soukup J, Zauner A, Doppenberg EM et al,. Relationship between brain temperature, brain chemistry and oxygen delivery after severe human head injury: the effect of mild hypothermia. Neurol Res 2002 24 2 161-168 (Pubitemid 34169261)
24. Nilsson P, Hillered L, Ponten U et al,. Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats. J Cereb Blood Flow Metab 1990 10 5 631-637 (Pubitemid 20260943)
25. Bullock R, Zauner A, Woodward JJ et al,. Factors affecting excitatory amino acid release following severe human head injury. J Neurosurg 1998 89 4 507-518 (Pubitemid 28440917)
26. Engstrom M, Polito A, Reinstrup P et al,. Intracerebral microdialysis in severe brain trauma: the importance of catheter location. J Neurosurg 2005 102 3 460-469 (Pubitemid 43194037)
27. van Landeghem FK, Stover JF, Bechmann I et al,. Early expression of glutamate transporter proteins in ramified microglia after controlled cortical impact injury in the rat. Glia 2001 35 3 167-179 (Pubitemid 32827760)
28. Hlatky R, Furuya Y, Valadka AB et al,. Comparison of microdialysate arginine and glutamate levels in severely head-injured patient. Acta Neurochir Suppl 2002 81 347-349
29. Storck T, Schulte S, Hofmann K et al,. Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain. Proc Natl Acad Sci USA 1992 89 22 10955-10959
30. Kanthan R, Shuaib A. Clinical evaluation of extracellular amino acids in severe head trauma by intracerebral in vivo microdialysis. J Neurol Neurosurg Psychiatry 1995 59 3 326-327
31. Gallagher CN, Hutchinson PJ, Pickard JD. Neuroimaging in trauma. Curr Opin Neurol 2007 20 4 403-409 (Pubitemid 47051986)
32. Keidel M, Rieschke P, Stude P et al,. Antinociceptive reflex alteration in acute posttraumatic headache following whiplash injury. Pain 2001 92 3 319-326 (Pubitemid 32480161)
33. Lighthall JW, Dixon CE, Anderson TE. Experimental models of brain injury. J Neurotrauma 1989 6 2 83-97 (Pubitemid 19203457)
34. Morales DM, Marklund N, Lebold D et al,. Experimental models of traumatic brain injury: do we really need to build a better mousetrap? Neuroscience 2005 136 4 971-989 (Pubitemid 41790514)
35. Povlishock JT, Hayes RL, Michel ME et al,. Workshop on animal models of traumatic brain injury. J Neurotrauma 1994 11 6 723-732
36. Statler KD, Jenkins LW, Dixon CE et al,. The simple model versus the super model: translating experimental traumatic brain injury research to the bedside. J Neurotrauma 2001 18 11 1195-1206 (Pubitemid 33062543)