Early effect of peginterferon alpha-2b plus ribavirin treatment on blood pressure and insulin resistance in patients with chronic hepatitis C

Hepato-Gastroenterology

Volumn 58, Issue 107-108, 2011, Pages 875-879

  Taskoparan, Muharrem ^a   Serin, Ender ^a   Gokturk, Huseyin Savas ^a   Icer, Mustafa Okan ^a   Abaci, Kutlu ^a   Ozer, Birol ^a   Zumrutdal, Aysegul ^a   Yilmaz, Ugur ^a  

^a BASKENT UNIVERSITY   (Turkey)

Author keywords

Blood pressure; Chronic hepatitis C; Insulin resistance; Peginterferon

Indexed keywords

AMINOTRANSFERASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PEGINTERFERON ALPHA2B PLUS RIBAVIRIN; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; BLOOD CELL COUNT; BLOOD PRESSURE MONITORING; BODY MASS; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; DIASTOLIC BLOOD PRESSURE; DRUG EFFECT; DRUG MECHANISM; FEMALE; HEPATITIS C; HUMAN; HYPERTENSION; INSULIN RESISTANCE; MALE; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; AGED; ANTIVIRAL AGENTS; BLOOD PRESSURE; BLOOD PRESSURE MONITORING, AMBULATORY; DRUG THERAPY, COMBINATION; FEMALE; HEART RATE; HEPATITIS C, CHRONIC; HUMANS; INSULIN RESISTANCE; INTERFERON ALFA-2B; LIPIDS; MALE; MIDDLE AGED; POLYETHYLENE GLYCOLS; RIBAVIRIN;

EID: 80051621801     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Sonnenblick M, Rosin A: Cardiotoxicity of interferon. A review of 44 cases. Chest. 1991; 99:557-561.
2. Teragawa H, Hondo T, Amano H, et al.: Adverse effects of interferon on the cardiovascular system in patients with chronic hepatitis C. Jpn Heart J 199637:905-915,.
3. Okuse C, Yotsuyanagi H, Nagase Y, Kobayashi Y, Yasuda K, Koike K, Iino S, Suzuki M, Itoh F: Risk factors for retinopathy associated with interferon alpha-2b and ribavirin combination therapy in patients with chronic hepatitis C. World J Gastroenterol. Jun 2006; 21:3756-3759. (Pubitemid 43950955)
4. Fukuhara M, Matsumura K, Ohmori S, Yanai T, Tsubota Y, Abe I, Fujishima M: Effects of interferon on circadian changes in blood pressure and heart rate variability in patients with chronic hepatitis. Am J Hypertens 1999; 12(5):519-523, 1999.
5. Condat B, Asselah T, Zanditenas D, Estampes B, Cohen A, O'Toole D, Bonnet J, Ngo Y, Marcellin P, Blazquez M: Fatal cardiomyopathy associated with pegylated interferon/ribavirin in a patient with chronic hepatitis C. Eur J Gastroenterol Hepatol 2006; 18(3):287-289.
6. Erol MK, Erol S, Koruk M, Ertek M, Bozkurt E: Effects of interferon-alpha therapy on cardiac function in patients with chronic hepatitis B infection. Heart Vessels 2004; 19(6):263-266. (Pubitemid 39600416)
7. Weinman SA, Belalcazar LM: Hepatitis C: a metabolic liver disease. Gastroenterology 2004; 126(3):917-919.
8. Mello V, Cruz T, Nunez G, Simoes MT, Ney-Oliveira F, Braga H, Araujo C, Cunha S, Schinoni MI, Cruz M, Parana R: Peripheral insulin resistance during treatment of chronic hepatitis C with pegylated interferon plus ribavirin. J Med Virol 2006; 78:1406-1410. (Pubitemid 44533868)
9. Kawaguchi T, Ide T, Taniguchi E, Hirano E, Itou M, Sumie S, Nagao Y, Yanagimoto C, Hanada S, Koga H, Sata M: Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2. Am J Gastroenterol 2007; 102(3):570-576. (Pubitemid 46328143)
10. Siagris D, Christofidou M, Theocharis GJ, Pagoni N, Papadimitriou C, Lekkou A, Thomopoulos K, Starakis I, Tsamandas AC, Labropoulou-Karatza C: Serum lipid pattern in chronic hepatitis C: histological and virological correlations. J Viral Hepat 2006; 13(1):56-61.
11. Hamamoto S, Uchida Y, Wada T, Moritani M, Sato S, Hamamoto N, Ishihara S, Watanabe M, Kinoshita Y: Changes in serum lipid concentrations in patients with chronic hepatitis C virus positive hepatitis responsive or non-responsive to interferon therapy. J Gastroenterol Hepatol 2005; 20(2):204-208. (Pubitemid 40343272)
12. Naeem M, Bacon BR, Mistry B, Britton RS, Di Bisceglie AM: Changes in serum lipoprotein profile during interferon therapy in chronic hepatitis C. Am J Gastroenterol 2001; 96:2468-2472. (Pubitemid 32769213)