Suicidal attempts in bipolar disorder: Results from an observational study (EMBLEM)

Bipolar Disorders

Volumn 13, Issue 4, 2011, Pages 377-386

  Bellivier, Frank ^a,b,c,d   Yon, Liova ^a,c,d   Luquiens, Amandine ^e   Azorin, Jean Michel ^d,f   Bertsch, Jordan ^g   Gerard, Stephanie ^h   Reed, Catherine ^h   Lukasiewicz, Michael ^i,j  

^a INSERM U955   (France)

^b UNIVERSITÉ PARIS EST   (France)

^c HENRI MONDOR HOSPITAL   (France)

^d Fondation Fondamental   (France)

^e BICHAT HOSPITAL   (France)

^f HÔPITAL SAINTE MARGUERITE   (France)

^g Serveis de Salut Mental ^*  (Spain)

^h ELI LILLY AND COMPANY   (United States)

ⁱ HÔPITAL PAUL BROUSSE   (France)

^j Universite Paris Sud   (France)

more..

Author keywords

Bipolar disorder; Prospective observational study; Suicide

Indexed keywords

BENZODIAZEPINE;

ACUTE DISEASE; ADULT; ALCOHOL ABUSE; ARTICLE; BIPOLAR DISORDER; CLINICAL GLOBAL IMPRESSION SCALE; COMORBIDITY; CONTROLLED STUDY; DEPRESSION; DISEASE DURATION; FEMALE; FOLLOW UP; GROUPS BY AGE; HAMILTON SCALE; HOSPITAL ADMISSION; HOSPITAL PATIENT; HUMAN; LIFE HISTORY; MAJOR CLINICAL STUDY; MALE; MANIA; MOOD DISORDER; OBSERVATIONAL STUDY; PATIENT COMPLIANCE; PRIORITY JOURNAL; SUBSTANCE ABUSE; SUICIDE ATTEMPT; SYMPTOM; YOUNG MANIA RATING SCALE;

ADULT; BIPOLAR DISORDER; CHI-SQUARE DISTRIBUTION; EUROPE; FEMALE; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; OBSESSIVE BEHAVIOR; PSYCHIATRIC STATUS RATING SCALES; SUICIDE, ATTEMPTED;

EID: 80051619907     PISSN: 13985647     EISSN: 13995618     Source Type: Journal    
DOI: 10.1111/j.1399-5618.2011.00926.x     Document Type: Article

References (50)

1. Tondo L, Isacsson G, Baldessarini R. Suicidal behavior in bipolar disorder: risk and prevention. CNS Drugs 2003; 17: 491-511.
2. Rihmer Z. Prediction and prevention of suicide in bipolar disorders. Clin Neuropsychiatry 2005; 2: 48-54.
3. Baldessarini RJ, Tondo L, Davis P, Pompili M, Goodwin FK, Hennen J. Decreased risk of suicides and attempts during long-term lithium treatment: a meta-analytic review. Bipolar Disord 2006; 8: 625-639.
4. Dunner DL. Clinical consequences of under-recognized bipolar spectrum disorder. Bipolar Disord 2003; 5: 456-463.
5. Goodwin FK, Jamison KR. Manic-Depressive Illness: Bipolar Disorders and Recurrent Depression, 2nd Edition. New York: Oxford University Press, 2007.
6. Angst J, Angst F, Gerber-Werder R, Gamma A. Suicide in 406 mood-disorder patients with and without long-term medication: a 40 to 44years' follow-up. Arch Suicide Res 2005; 9: 279-300.
7. Arvilommi P, Suominen KS, Mantere OK, Leppämäki S, Valtonen H, Isometsä ET. Adequacy of treatment received by diagnosed and undiagnosed patients with bipolar I and II disorders. J Clin Psychiatry 2007; 68: 102-110.
8. Jamison KR. Suicide and bipolar disorder. J Clin Psychiatry 2000; 61 (Suppl. 9): 47-51.
9. Hawton K, Sutton L, Haw C, Sinclair J, Harriss L. Suicide and attempted suicide in bipolar disorder: a systematic review of risk factors. J Clin Psychiatry 2005; 66: 693-704.
10. Cheng AT, Chen TH, Chen CC, Jenkins R. Psychosocial and psychiatric risk factors for suicide. Case-control psychological autopsy study. Br J Psychiatry 2000; 177: 360-365.
11. Foster T, Gillespie K, McClelland R. Mental disorders and suicide in Northern Ireland. Br J Psychiatry 1997; 170: 447-452.
12. Slama F, Bellivier F, Henry C et al. Bipolar patients with suicidal behaviour: toward the identification of a clinical subgroup. J Clin Psychiatry 2004; 65: 1035-1039.
13. Lopez P, Mosquera F, de Leon J et al. Suicide attempts in bipolar patients. J Clin Psychiatry 2001; 62: 963-966.
14. MacKinnon DF, Zandi PP, Gershon E, Nurnberger JI Jr, Reich T, DePaulo JR. Rapid switching of mood in families with multiple cases of bipolar disorder. Arch Gen Psychiatry 2003; 60: 921-928.
15. Simpson SG, Jamison KR. The risk of suicide in patients with bipolar disorder. J Clin Psychiatry 1999; 60 (Suppl. 2): 53-56.
16. Azorin JM, Kaladjian A, Adida M et al. Risk factors associated with lifetime suicide attempts in bipolar I patients: findings from a French National Cohort. Compr Psychiatry 2009; 50: 115-120.
17. Leverich GS, Altshuler LL, Frye MA et al. Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network. J Clin Psychiatry 2003; 64: 506-515.
18. Gonzalez-Pinto A, Mosquera F, Alonso M et al. Suicidal risk in bipolar I disorder patients and adherence to long-term lithium treatment. Bipolar Disord 2006; 8: 618-624.
19. Ghaemi SN, Rosenquist KJ, Ko JY, Baldasano CF, Kontos NJ, Baldessarini RJ. Antidepressant treatment in bipolar versus unipolar depression. Am J Psychiatry 2004; 161: 163-165.
20. O'Donovan C, Garnham JS, Hajek T, Alda M. Antidepressant monotherapy in pre-bipolar depression; predictive value and inherent risk. J Affect Disord 2008; 107: 293-298.
21. Yatham LN. Diagnosis and management of patients with bipolar II disorder. J Clin Psychiatry 2005; 66 (Suppl. 1): 13-17.
22. Yerevanian BI, Koek RJ, Mintz J. Bipolar pharmacotherapy and suicidal behavior. Part 1: Lithium, divalproex and carbamazepine. J Affect Disord 2007; 103: 5-11.
23. Yerevanian BI, Koek RJ, Mintz J, Akiskal HS. Bipolar pharmacotherapy and suicidal behavior. Part 2. The impact of antidepressants. J Affect Disord 2007; 103: 13-21.
24. Yerevanian BI, Koek RJ, Mintz J. Bipolar pharmacotherapy and suicidal behavior Part 3: impact of antipsychotics. J Affect Disord 2007; 103: 23-28.
25. Galfalvy H, Oquendo MA, Carballo JJ et al. Clinical predictors of suicidal acts after major depression in bipolar disorder: a prospective study. Bipolar Disord 2006; 8: 586-595.
26. Oquendo MA, Waternaux C, Brodsky B et al. Suicidal behavior in bipolar mood disorder: clinical characteristics of attempters and nonattempters. J Affect Disord 2000; 59: 107-117.
27. Serretti A, Mandelli L, Lattuada E, Smeraldi E. Rapid cycling mood disorder: clinical and demographic features. Compr Psychiatry 2002; 43: 336-343.
28. Goldberg JF, Ernst CL. Features associated with the delayed initiation of mood stabilizers at illness onset in bipolar disorder. J Clin Psychiatry 2002; 63: 985-991.
29. Reed C, Novick D, Gonzalez-Pinto A, Bertsch J, Haro JM. Observational study designs for bipolar disorder-what can they tell us about treatment in acute mania? Prog Neuropsychopharmacol Biol Psychiatry 2009; 33: 715-721.
30. Haro JM, Kontodimas S, Negrin MA, Ratcliffe M, Suarez D, Windmeijer F. Methodological aspects in the assessment of treatment effects in observational health outcomes studies. Appl Health Econ Health Policy 2006; 5: 11-25.
31. Goetz I, Tohen M, Reed C, Lorenzo M, Vieta E, EMBLEM Advisory Board. Functional impairment in patients with mania: baseline results of the EMBLEM study. Bipolar Disord 2007; 9: 45-52.
32. Haro JM, van Os J, Vieta E et al. Evidence for three distinct classes of 'typical', 'psychotic' and 'dual' mania: results from the EMBLEM study. Acta Psychiatr Scand 2006; 113: 112-120.
33. Vieta E, Panicali F, Goetz I et al. Olanzapine monotherapy and olanzapine combination therapy in the treatment of mania: 12-week results from the European Mania in Bipolar Longitudinal Evaluation of Medication (EMBLEM) observational study. J Affect Disord 2008; 106: 63-72.
34. Spearing MK, Post RM, Leverich GS, Brandt D, Nolen W. Modification of the Clinical Global Impressions (CGI) scale for use in bipolar illness (BP): the CGI-BP. Psychiatr Res 1997; 73: 159-171.
35. Guy W. Clinical global impression. ECDEU Assessment Manual for Psychopharmacology, revised. (DHEW Publication No. ADM76-336) Rockville, MD: National Institute of Mental Health, 1976: 217-222.
36. Young RC, Biggs JT, Ziegler VE, Meyer DA. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 1978; 133: 429-435.
37. González-Pinto A, Mosquera F, Reed C et al. Validity and reliability of the Hamilton Depression Rating Scale (5 items) for manic and mixed bipolar disorders. J Nerv Ment Dis 2009; 197: 682-686.
38. González-Pinto A, Ballesteros J, Aldama A et al. Principal components of mania. J Affect Disord 2003; 76: 95-102.
39. Valtonen HM, Suominen K, Mantere O, Leppämäki S, Arvilommi P, Isometsä E. Suicidal behaviour during different phases of bipolar disorder. J Affect Disord 2007; 97: 101-107.
40. Schurhoff F, Bellivier F, Jouvent R et al. Early and late onset bipolar disorders: two different forms of manic-depressive illness? J Affect Disord 2000; 58: 215-221.
41. Schulze TG, Muller DJ, Krauss H et al. Further evidence for age at onset being an indicator for severity in bipolar disorder. J Affect Disord 2002; 68: 343-345.
42. Strakowski SM, McElroy SL, Keck PE Jr, West SA. Suicidality among patients with mixed and manic bipolar disorder. Am J Psychiatry 1996; 153: 674-676.
43. Tondo L, Baldessarini RJ, Henner J et al. Suicide attempts in major affective disorder patients with comorbid substance use disorders. J Clin Psychiatry 1999; 60 (Suppl. 2): 63-69.
44. National Institute for Health and Clinical Excellence (NICE). Bipolar Disorder: The Management of Bipolar Disorder in Adults, Children and Adolescents, in Primary and Secondary Care. London: National Clinical Practice Guideline Number 38, July 2006. Available at.
45. Yatham LN, Kennedy SH, Schaffer A et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2009. Bipolar Disord 2009; 11: 225-255.
46. Tondo L, Hennen J, Baldessarini RJ. Lower suicide risk with long-term lithium treatment in major affective illness: a meta-analysis. Acta Psychiatr Scand 2001; 104: 163-172.
47. Müller-Oerlinghausen B, Muser-Causemann B, Volk J. Suicides and parasuicides in a high-risk patient group on and off lithium long-term medication. J Affect Disord 1992; 25: 261-269.
48. Rosa AR, Cruz N, Franco C et al. Why do clinicians maintain antidepressants in some patients with acute mania? Hints from the European Mania in Bipolar Longitudinal Evaluation of Medication (EMBLEM), a large, naturalistic study. J Clin Psychiatry 2010; 71: 1000-1006.
49. Leverich GS, Post RM. Course of bipolar illness after history of childhood trauma. Lancet 2006; 367: 1040-1042.
50. Zimmerman M, Ruggero CJ, Chelminski I, Young D. Is bipolar disorder overdiagnosed? J Clin Psychiatry 2008; 69: 935-940.