-
1
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. 2009; 460(7253): 392-395.
-
(2009)
Nature
, vol.460
, Issue.7253
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle, C.M.5
Flurkey, K.6
Nadon, N.L.7
Wilkinson, J.E.8
Frenkel, K.9
Carter, C.S.10
Pahor, M.11
Javors, M.A.12
Fernandez, E.13
Miller, R.A.14
-
2
-
-
77949882117
-
The tuberous sclerosis complex
-
Orlova KA, Crino PB. The tuberous sclerosis complex. Ann N Y Acad Sci. 2010; 1184: 87-105.
-
(2010)
Ann N Y Acad Sci
, vol.1184
, pp. 87-105
-
-
Orlova, K.A.1
Crino, P.B.2
-
3
-
-
33750044112
-
Stress and mTORture signalling
-
Reiling JH, Sabatini DM. Stress and mTORture signalling. Oncogene. 2006; 25: 6373-6383.
-
(2006)
Oncogene
, vol.25
, pp. 6373-6383
-
-
Reiling, J.H.1
Sabatini, D.M.2
-
4
-
-
74549205329
-
Validation of anti-aging drugs by treating age-related diseases
-
Blagosklonny MV. Validation of anti-aging drugs by treating age-related diseases. Aging. 2009; 1(3): 281-288.
-
(2009)
Aging
, vol.1
, Issue.3
, pp. 281-288
-
-
Blagosklonny, M.V.1
-
5
-
-
78650987740
-
Tuberous sclerosis complex: neurological, renal and pulmonary manifestations
-
Franz DN, Bissler JJ, McCormack FX. Tuberous sclerosis complex: neurological, renal and pulmonary manifestations. Neuropediatrics. 2010; 41: 199-208.
-
(2010)
Neuropediatrics
, vol.41
, pp. 199-208
-
-
Franz, D.N.1
Bissler, J.J.2
McCormack, F.X.3
-
8
-
-
36749049305
-
Intrafamilial phenotypic variability in tuberous sclerosis complex
-
Lyczkowski DA, Conant KD, Pulsifer MB, Jarrett DY, Grant PE, Kwiatkowski DJ, Thiele EA: Intrafamilial phenotypic variability in tuberous sclerosis complex. J Child Neurol. 2007; 22(12):1348-1355.
-
(2007)
J Child Neurol.
, vol.22
, Issue.12
, pp. 1348-1355
-
-
Lyczkowski, D.A.1
Conant, K.D.2
Pulsifer, M.B.3
Jarrett, D.Y.4
Grant, P.E.5
Kwiatkowski, D.J.6
Thiele, E.A.7
-
10
-
-
7044245656
-
Subependymal giant cell tumors in tuberous sclerosis complex
-
Goh S, Butler W, Thiele EA. Subependymal giant cell tumors in tuberous sclerosis complex. Neurology. 2004; 63: 1457-1461.
-
(2004)
Neurology
, vol.63
, pp. 1457-1461
-
-
Goh, S.1
Butler, W.2
Thiele, E.A.3
-
11
-
-
33644827461
-
Rapamycin cause regression of astrocytomas in tuberous sclerosis complex
-
Franz DN, Leonard J, Tudor C, Chuck G, Care M, Sethuraman G, Dinopoulos A, Thomas G, Crone KR. Rapamycin cause regression of astrocytomas in tuberous sclerosis complex. Ann Neurol. 2006; 59: 490-498.
-
(2006)
Ann Neurol
, vol.59
, pp. 490-498
-
-
Franz, D.N.1
Leonard, J.2
Tudor, C.3
Chuck, G.4
Care, M.5
Sethuraman, G.6
Dinopoulos, A.7
Thomas, G.8
Crone, K.R.9
-
12
-
-
77957922822
-
Rapamycin as an alternative to surgical treatment of subependymal giant cell astrocytomas in a patient with tuberous sclerosis complex
-
Birca A, Mercier C, Major P. Rapamycin as an alternative to surgical treatment of subependymal giant cell astrocytomas in a patient with tuberous sclerosis complex. J Neurosurg Pediatrics.2010; 6: 381-384.
-
(2010)
J Neurosurg Pediatrics
, vol.6
, pp. 381-384
-
-
Birca, A.1
Mercier, C.2
Major, P.3
-
13
-
-
78049510428
-
Everolimus for Subependymal Giant-Cell Astrocytomas in Tuberous Sclerosis
-
Krueger DA, Care MM, Holland KM, Agricola K, Tudor C, Mangeshkar P, Wilson KA, Byars A, Sahmoud T, Franz DN. Everolimus for Subependymal Giant-Cell Astrocytomas in Tuberous Sclerosis. N Engl J Med. 2010; 363:1801-1811.
-
(2010)
N Engl J Med
, vol.36
, pp. 1801-1811
-
-
Krueger, D.A.1
Care, M.M.2
Holland, K.M.3
Agricola, K.4
Tudor, C.5
Mangeshkar, P.6
Wilson, K.A.7
Byars, A.8
Sahmoud, T.9
Franz, D.N.10
-
14
-
-
38049169559
-
Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis
-
Bissler JJ, McCormack FX, Young LR, Elwing JM, Chuck G, Leonard JM, Schmithorst VJ, Laor T, Brody AS, Bean J, Salisbury S, Franz DN. Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis. N Engl J Med. 2008; 358: 140-151.
-
(2008)
N Engl J Med.
, vol.358
, pp. 140-151
-
-
Bissler, J.J.1
McCormack, F.X.2
Young, L.R.3
Elwing, J.M.4
Chuck, G.5
Leonard, J.M.6
Schmithorst, V.J.7
Laor, T.8
Brody, A.S.9
Bean, J.10
Salisbury, S.11
Franz, D.N.12
-
15
-
-
49149088555
-
Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis
-
Ehninger D, Han S, Shilyansky C, Zhou Y, Li W, Kwiatkowski DJ, Ramesh V, Silva AJ. Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis. Nat Med. 2008; 14: 843-848.
-
(2008)
Nat Med
, vol.14
, pp. 843-848
-
-
Ehninger, D.1
Han, S.2
Shilyansky, C.3
Zhou, Y.4
Li, W.5
Kwiatkowski, D.J.6
Ramesh, V.7
Silva, A.J.8
-
16
-
-
76249084241
-
Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies
-
Wong M. Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies. Epilepsia. 2010; 51: 27-36.
-
(2010)
Epilepsia
, vol.51
, pp. 27-36
-
-
Wong, M.1
-
17
-
-
77956190850
-
Gonadal dysfunction and infertility in kidney transplant patients receiving sirolimus
-
Boobes Y, Bernieh B, Saadi H, Raafat Al Hakim M, Abouchacra S. Gonadal dysfunction and infertility in kidney transplant patients receiving sirolimus. Int Urol Nephrol. 2010; 42(2): 493-498.
-
(2010)
Int Urol Nephrol.
, vol.42
, Issue.2
, pp. 493-498
-
-
Boobes, Y.1
Bernieh, B.2
Saadi, H.3
Raafat Al Hakim, M.4
Abouchacra, S.5
|