An attempt to replicate interaction between coffee and CYP1A2 gene in connection to Parkinson's disease

European Journal of Neurology

Volumn 18, Issue 9, 2011, Pages

  Hill Burns, E M ^a   Hamza, T H ^a   Zabetian, C P ^b   Factor, S A ^c   Payami, H ^a  

^a WADSWORTH CENTER   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Coffee; CYP1A2; Parkinson's disease

Indexed keywords

CYTOCHROME P450 1A2;

ADULT; CASE CONTROL STUDY; CAUCASIAN; CIGARETTE SMOKING; COFFEE; CONTROLLED STUDY; DIETARY INTAKE; EUROPEAN AMERICAN; FEMALE; GENOTYPE; HUMAN; LETTER; MAJOR CLINICAL STUDY; MALE; METABOLISM; NEUROLOGIC DISEASE; PARKINSON DISEASE; POPULATION STRUCTURE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

CAFFEINE; CYTOCHROME P-450 CYP1A2; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; NEUROPROTECTIVE AGENTS; PARKINSON DISEASE; RECEPTOR, ADENOSINE A2A;

EID: 80051593066     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2011.03464.x     Document Type: Letter

References (6)

1. Popat RA, Van Den Eeden SK, Tanner CM, et al. Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson's disease. Eur J Neurol 2011; 18: 756-765.
2. Mellick GD, Ross OA. Caffeine and Parkinson's disease: are we getting our fix on risk-modifying gene-environment interactions? Eur J Neurol 2011; 18: 671-672.
3. Hamza TH, Zabetian CP, Tenesa A, et al. Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease. Nat Genet 2010; 42: 781-785.
4. Powers KM, Kay DM, Factor SA, et al. Combined effects of smoking, coffee, and NSAIDs on Parkinson's disease risk. Mov Disord 2008; 23: 88-95.
5. Howie BN, Donnelly P, Marchini J. A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genetics 2009; 5: e1000529.
6. Zevin S, Benowitz NL. Drug interactions with tobacco smoking. An update. Clin Pharmacokinet 1999; 36: 425-438.