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Volumn 2, Issue 3, 2008, Pages 436-449

In Silico simulation of long-term type 1 diabetes glycemic control treatment outcomes

Author keywords

Blood glucose; Compartmental models; Decision support; Diabetes; Hyperglycemia; Insulin; Simulation; Subcutaneous injection

Indexed keywords


EID: 80051592581     PISSN: None     EISSN: 19322968     Source Type: Journal    
DOI: 10.1177/193229680800200313     Document Type: Conference Paper
Times cited : (8)

References (54)
  • 1
    • 14844351848 scopus 로고    scopus 로고
    • A critical assessment of algorithms and challenges in the development of a closed-loop artificial pancreas
    • Bequette BW. A critical assessment of algorithms and challenges in the development of a closed-loop artificial pancreas. Diabetes Technol Ther. 2005;7(1):28-47.
    • (2005) Diabetes Technol Ther. , vol.7 , Issue.1 , pp. 28-47
    • Bequette, B.W.1
  • 2
    • 0035156628 scopus 로고    scopus 로고
    • The subcutaneous route to insulin-dependent diabetes therapy
    • Bellazzi R, Nucci G, Cobelli C. The subcutaneous route to insulin-dependent diabetes therapy. IEEE Eng Med Biol Mag. 2001;20(1):54-64.
    • (2001) IEEE Eng Med Biol Mag , vol.20 , Issue.1 , pp. 54-64
    • Bellazzi, R.1    Nucci, G.2    Cobelli, C.3
  • 3
    • 33845521334 scopus 로고    scopus 로고
    • Feasibility of automating insulin delivery for the treatment of type 1 diabetes
    • Steil GM, Rebrin K, Darwin C, Hariri F, Saad MF. Feasibility of automating insulin delivery for the treatment of type 1 diabetes. Diabetes. 2006;55(12):3344-50.
    • (2006) Diabetes , vol.55 , Issue.12 , pp. 3344-3350
    • Steil, G.M.1    Rebrin, K.2    Darwin, C.3    Hariri, F.4    Saad, M.F.5
  • 4
    • 1642452596 scopus 로고    scopus 로고
    • Closed-loop insulin deliverythe path to physiological glucose control
    • Steil GM, Panteleon AE, Rebrin K. Closed-loop insulin deliverythe path to physiological glucose control. Adv Drug Deliv Rev. 2004;56(2):125-44.
    • (2004) Adv Drug Deliv Rev. , vol.56 , Issue.2 , pp. 125-144
    • Steil, G.M.1    Panteleon, A.E.2    Rebrin, K.3
  • 5
    • 18144421498 scopus 로고    scopus 로고
    • Continuous glucose monitoring: Roadmap for 21st century diabetes therapy
    • Klonoff DC, Continuous glucose monitoring: roadmap for 21st century diabetes therapy. Diabetes Care. 2005;28(5):1231-9.
    • (2005) Diabetes Care , vol.28 , Issue.5 , pp. 1231-1239
    • Klonoff, D.C.1
  • 6
    • 84887144492 scopus 로고    scopus 로고
    • Guidance on the use of continuous subcutaneous insulin infusion for diabetes, National Institute for Clinical Excellence; 2003
    • Guidance on the use of continuous subcutaneous insulin infusion for diabetes. Technology Appraisal Guidance No. 57, National Institute for Clinical Excellence; 2003. Available from: www.nice.org.uk.
    • Technology Appraisal Guidance No. 57
  • 7
    • 85039634889 scopus 로고    scopus 로고
    • Position statement on insulin pump therapy, Diabetes UK cited 2007 Aug. 8
    • Position statement on insulin pump therapy. Position statement on insulin pump therapy, Diabetes UK [cited 2007 Aug. 8]. Available from: www.diabetes.org.uk.
    • Position Statement on Insulin Pump Therapy
  • 8
    • 32144448938 scopus 로고    scopus 로고
    • Standards of medical care in diabetes-2006
    • ADA
    • ADA. Standards of medical care in diabetes-2006. Diabetes Care. 2006;29; S4-S42.
    • (2006) Diabetes Care , vol.29
  • 11
    • 0041666413 scopus 로고    scopus 로고
    • Clinical performance of CGMS in type 1 diabetic patients treated by continuous subcutaneous insulin infusion using insulin analogs
    • Guerci B, Floriot M, Böhme P, Durain D, Benichou M, Jellimann S, Drouin P. Clinical performance of CGMS in type 1 diabetic patients treated by continuous subcutaneous insulin infusion using insulin analogs. Diabetes Care. 2003;26(3):582-9.
    • (2003) Diabetes Care , vol.26 , Issue.3 , pp. 582-589
    • Guerci, B.1    Floriot, M.2    Böhme, P.3    Durain, D.4    Benichou, M.5    Jellimann, S.6    Drouin, P.7
  • 12
    • 0036701596 scopus 로고    scopus 로고
    • Novel insulins: Expanding options in diabetes management
    • Gerich JE. Novel insulins: expanding options in diabetes management. Am J Med. 2002;113(4):308-16.
    • (2002) Am J Med. , vol.113 , Issue.4 , pp. 308-316
    • Gerich, J.E.1
  • 14
    • 27644564028 scopus 로고    scopus 로고
    • Diabetes website review
    • Reed K, Lehmann ED. Diabetes website review: www.2aida.org. Diabetes Technol Ther. 2005;7(5):741-54.
    • (2005) Diabetes Technol Ther. , vol.7 , Issue.5 , pp. 741-754
    • Reed, K.1    Lehmann, E.D.2
  • 15
    • 25644437034 scopus 로고    scopus 로고
    • Subcutaneous insulin: Pharmacokinetic variability and glycemic variability
    • Guerci B, Sauvanet JP. Subcutaneous insulin: pharmacokinetic variability and glycemic variability. Diabetes Metab. 2005;31(4 Pt 2):4S7-4S24.
    • (2005) Diabetes Metab. , vol.31 , Issue.4 PART 2
    • Guerci, B.1    Sauvanet, J.P.2
  • 16
    • 0345169029 scopus 로고    scopus 로고
    • Evolving approaches to intensive insulin therapy in type 1 diabetes: Multiple daily injections, insulin pumps and new methods of monitoring
    • Stephens E, Riddle M. Evolving approaches to intensive insulin therapy in type 1 diabetes: multiple daily injections, insulin pumps and new methods of monitoring. Rev Endocr Metab Disord. 2003;4(4):325-34.
    • (2003) Rev Endocr Metab Disord , vol.4 , Issue.4 , pp. 325-334
    • Stephens, E.1    Riddle, M.2
  • 17
    • 0344844376 scopus 로고    scopus 로고
    • Prospective audit of the introduction of insulin glargine (lantus) into clinical practice in type 1 diabetic patients
    • Gallen IW, Carter C. Prospective audit of the introduction of insulin glargine (lantus) into clinical practice in type 1 diabetic patients. Diabetes Care. 2003;26(12):3352-3.
    • (2003) Diabetes Care , vol.26 , Issue.12 , pp. 3352-3353
    • Gallen, I.W.1    Carter, C.2
  • 18
    • 33846806218 scopus 로고    scopus 로고
    • From the coalface: Does glargine insulin improve hypoglycaemic episodes, glycaemic control or affect body mass in type 1 diabetic subjects who are attending a 'routine' diabetes clinic?
    • Distiller LA, Joffe BI. From the coalface: does glargine insulin improve hypoglycaemic episodes, glycaemic control or affect body mass in type 1 diabetic subjects who are attending a 'routine' diabetes clinic? Diabetologia. 2006;49(11):2793-4.
    • (2006) Diabetologia , vol.49 , Issue.11 , pp. 2793-2794
    • Distiller, L.A.1    Joffe, B.I.2
  • 19
    • 0030915548 scopus 로고    scopus 로고
    • Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patients on insulin-analog treatment. Multicenter Insulin Lispro Study Group
    • Anderson JH Jr, Brunelle RL, Koivisto VA, Pfützner A, Trautmann ME, Vignati L, Di Marchi R. Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patients on insulin-analog treatment. Multicenter Insulin Lispro Study Group. Diabetes. 1997;46(2):265-70.
    • (1997) Diabetes , vol.46 , Issue.2 , pp. 265-270
    • Anderson Jr., J.H.1    Brunelle, R.L.2    Koivisto, V.A.3    Pfützner, A.4    Trautmann, M.E.5    Vignati, L.6    Di Marchi, R.7
  • 20
    • 0034117810 scopus 로고    scopus 로고
    • Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo
    • Heinemann L, Linkeschova R, Rave K, Hompesch B, Sedlak M, Heise T. Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo. Diabetes Care. 2000;23(5):644-9.
    • (2000) Diabetes Care , vol.23 , Issue.5 , pp. 644-649
    • Heinemann, L.1    Linkeschova, R.2    Rave, K.3    Hompesch, B.4    Sedlak, M.5    Heise, T.6
  • 21
    • 26244437656 scopus 로고    scopus 로고
    • Glycaemic control and severe hypoglycaemia following training in flexible, intensive insulin therapy to enable dietary freedom in people with type 1 diabetes: A prospective implementation study
    • Sämann A, Mühlhauser I, Bender R, Kloos Ch, Müller UA. Glycaemic control and severe hypoglycaemia following training in flexible, intensive insulin therapy to enable dietary freedom in people with type 1 diabetes: a prospective implementation study. Diabetologia. 2005;48(10):1965-70.
    • (2005) Diabetologia , vol.48 , Issue.10 , pp. 1965-1970
    • Sämann, A.1    Mühlhauser, I.2    Bender, R.3    Ch, K.4    Müller, U.A.5
  • 22
    • 77951019655 scopus 로고    scopus 로고
    • A subcutaneous insulin pharmacokinetic model for computer simulation in a diabetes decision support role: Model structure and parameter identification
    • In press
    • Wong J, Chase JG, Hann CE, Shaw GM, Lotz TF, Lin J, Le Compte AJ. A subcutaneous insulin pharmacokinetic model for computer simulation in a diabetes decision support role: model structure and parameter identification. J Diabetes Sci Technol. In press 2008.
    • (2008) J Diabetes Sci Technol
    • Wong, J.1    Chase, J.G.2    Hann, C.E.3    Shaw, G.M.4    Lotz, T.F.5    Lin, J.6    Le Compte, A.J.7
  • 23
    • 77951019655 scopus 로고    scopus 로고
    • A subcutaneous insulin pharmacokinetic model for computer simulation in a diabetes decision support role: Validation and simulation
    • In press
    • Wong J, Chase JG, Hann CE, Shaw GM, Lotz TF, Lin J, Le Compte AJ. A subcutaneous insulin pharmacokinetic model for computer simulation in a diabetes decision support role: validation and simulation. J Diabetes Sci Technol. In press 2008.
    • (2008) J Diabetes Sci Technol
    • Wong, J.1    Chase, J.G.2    Hann, C.E.3    Shaw, G.M.4    Lotz, T.F.5    Lin, J.6    Le Compte, A.J.7
  • 26
    • 0028512019 scopus 로고
    • Use of carbohydrate counting for meal planning in type I diabetes
    • Gregory RP, Davis DL. Use of carbohydrate counting for meal planning in type I diabetes. Diabetes Educ. 1994;20(5):406-9.
    • (1994) Diabetes Educ. , vol.20 , Issue.5 , pp. 406-409
    • Gregory, R.P.1    Davis, D.L.2
  • 28
    • 0027335504 scopus 로고
    • AIDA2: A Mk. II automated insulin dosage advisor
    • Lehmann ED, Deutsch T. AIDA2: A Mk. II automated insulin dosage advisor. J Biomed Eng. 1993;15(3):201-11.
    • (1993) J Biomed Eng. , vol.15 , Issue.3 , pp. 201-211
    • Lehmann, E.D.1    Deutsch, T.2
  • 30
    • 85039644130 scopus 로고
    • The pocket pancreas: Your diabetes guide for improved blood sugars
    • Walsh J, Roberts R. The pocket pancreas: your diabetes guide for improved blood sugars. Diabetes Services Inc.; 1994.
    • (1994) Diabetes Services Inc.
    • Walsh, J.1    Roberts, R.2
  • 32
    • 4544250123 scopus 로고    scopus 로고
    • Minimal model estimation of glucose absorption and insulin sensitivity from oral test: Validation with a tracer method
    • Dalla Man C, Caumo A, Basu R, Rizza R, Toffolo G, Cobelli C. Minimal model estimation of glucose absorption and insulin sensitivity from oral test: validation with a tracer method. Am J Physiol Endocrinol Metab. 2004;287(4):E637-43.
    • (2004) Am J Physiol Endocrinol Metab. , vol.287 , Issue.4
    • Dalla Man, C.1    Caumo, A.2    Basu, R.3    Rizza, R.4    Toffolo, G.5    Cobelli, C.6
  • 33
    • 5144235349 scopus 로고    scopus 로고
    • Glucose appearance in the peripheral circulation and liver glucose output in men after a large 13C starch meal
    • Korach-André M, Roth H, Barnoud D, Péan M, Péronnet F, Leverve X. Glucose appearance in the peripheral circulation and liver glucose output in men after a large 13C starch meal. Am J Clin Nutr. 2004;80(4):881-6.
    • (2004) Am J Clin Nutr , vol.80 , Issue.4 , pp. 881-886
    • Korach-André, M.1    Roth, H.2    Barnoud, D.3    Péan, M.4    Péronnet, F.5    Leverve, X.6
  • 34
    • 0032896693 scopus 로고    scopus 로고
    • Improved postprandial glycemic control with insulin aspart. A randomized double-blind cross-over trial in type 1 diabetes
    • Lindholm A, McEwen J, Riis AP. Improved postprandial glycemic control with insulin aspart. A randomized double-blind cross-over trial in type 1 diabetes. Diabetes Care. 1999;22(5):801-5.
    • (1999) Diabetes Care , vol.22 , Issue.5 , pp. 801-805
    • Lindholm, A.1    McEwen, J.2    Riis, A.P.3
  • 36
    • 0038131919 scopus 로고    scopus 로고
    • Glimepiride combined with morning insulin glargine, bedtime neutral protamine hagedorn insulin, or bedtime insulin glargine in patients with type 2 diabetes. A randomized, controlled trial
    • 4001 Study Group
    • Fritsche A, Schweitzer MA, Häring HU; 4001 Study Group. Glimepiride combined with morning insulin glargine, bedtime neutral protamine hagedorn insulin, or bedtime insulin glargine in patients with type 2 diabetes. A randomized, controlled trial. Ann Intern Med. 2003;138(12):952-9.
    • (2003) Ann Intern Med. , vol.138 , Issue.12 , pp. 952-959
    • Fritsche, A.1    Schweitzer, M.A.2    Häring, H.U.3
  • 37
    • 0242269000 scopus 로고    scopus 로고
    • The treat-to-target trial: Randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients
    • Insulin Glargine 4002 Study Investigators
    • Riddle MC, Rosenstock J, Gerich J; Insulin Glargine 4002 Study Investigators. The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care. 2003;26(11):3080-6.
    • (2003) Diabetes Care , vol.26 , Issue.11 , pp. 3080-3086
    • Riddle, M.C.1    Rosenstock, J.2    Gerich, J.3
  • 38
    • 0038147377 scopus 로고    scopus 로고
    • Using new insulin strategies in the outpatient treatment of diabetes: Clinical applications
    • De Witt DE, Dugdale DC. Using new insulin strategies in the outpatient treatment of diabetes: clinical applications. JAMA. 2003;289(17):2265-9.
    • (2003) JAMA , vol.289 , Issue.17 , pp. 2265-2269
    • De Witt, D.E.1    Dugdale, D.C.2
  • 39
    • 0021941892 scopus 로고
    • A practical guide to basal and prandial insulin therapy
    • Holman RR, Turner RC. A practical guide to basal and prandial insulin therapy. Diabet Med. 1985;2(1):45-53.
    • (1985) Diabet Med. , vol.2 , Issue.1 , pp. 45-53
    • Holman, R.R.1    Turner, R.C.2
  • 40
    • 33750992379 scopus 로고    scopus 로고
    • cited 2007 Oct. 11
    • Sanofi-Aventis, LANTUS (insulin glargine [rDNA origin] injection). Prescribing information [cited 2007 Oct. 11]. Available from: http://products.sanofi-aventis.us/lantus/lantus.html>
    • Prescribing Information
  • 41
    • 0036177713 scopus 로고    scopus 로고
    • Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus
    • Sacks DB, Bruns DE, Goldstein DE, Maclaren NK, McDonald JM, Parrott M. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem. 2002;48(3):436-72.
    • (2002) Clin Chem. , vol.48 , Issue.3 , pp. 436-472
    • Sacks, D.B.1    Bruns, D.E.2    Goldstein, D.E.3    Maclaren, N.K.4    McDonald, J.M.5    Parrott, M.6
  • 42
    • 0036482285 scopus 로고    scopus 로고
    • Defining the relationship between plasma glucose and HbA (1c): Analysis of glucose profiles and HbA (1c) in the Diabetes Control and Complications Trial
    • Rohlfing CL, Wiedmeyer HM, Little RR, England JD, Tennill A, Goldstein DE. Defining the relationship between plasma glucose and HbA (1c): analysis of glucose profiles and HbA (1c) in the Diabetes Control and Complications Trial. Diabetes Care. 2002;25(2):275-8.
    • (2002) Diabetes Care , vol.25 , Issue.2 , pp. 275-278
    • Rohlfing, C.L.1    Wiedmeyer, H.M.2    Little, R.R.3    England, J.D.4    Tennill, A.5    Goldstein, D.E.6
  • 43
    • 0034765245 scopus 로고    scopus 로고
    • Simulating glycosylated hemoglobin (HbA1c) levels in diabetes using an interactive educational virtual diabetes patient simulator
    • Lehmann ED. Simulating glycosylated hemoglobin (HbA1c) levels in diabetes using an interactive educational virtual diabetes patient simulator. Diabetes Technol Ther. 2001;3(3):517-24.
    • (2001) Diabetes Technol Ther. , vol.3 , Issue.3 , pp. 517-524
    • Lehmann, E.D.1
  • 44
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329(14):977-86.
    • (1993) N Engl J Med. , vol.329 , Issue.14 , pp. 977-986
  • 45
    • 0003191727 scopus 로고    scopus 로고
    • Medical guidelines for the management of diabetes mellitus: The AACE system of intensive diabetes self-management-2002 update
    • AACE
    • AACE. Medical guidelines for the management of diabetes mellitus: the AACE system of intensive diabetes self-management-2002 update. Endocr Prac. 2002;8(Suppl. 1):40-64.
    • (2002) Endocr Prac , vol.8 , Issue.SUPPL. 1 , pp. 40-64
  • 46
    • 0031784260 scopus 로고    scopus 로고
    • Improved glycemic control with insulin aspart: A multicenter randomized double-blind crossover trial in type 1 diabetic patients. UK Insulin Aspart Study Group
    • Home PD, Lindholm A, Hylleberg B, Round P. Improved glycemic control with insulin aspart: a multicenter randomized double-blind crossover trial in type 1 diabetic patients. UK Insulin Aspart Study Group. Diabetes Care. 1998;21(11):1904-9.
    • (1998) Diabetes Care , vol.21 , Issue.11 , pp. 1904-1909
    • Home, P.D.1    Lindholm, A.2    Hylleberg, B.3    Round, P.4
  • 47
    • 18144388647 scopus 로고    scopus 로고
    • Defining and reporting hypoglycemia in diabetes: A report from the American Diabetes Association Workgroup on Hypoglycemia
    • Workgroup on Hypoglycemia, American Diabetes Association
    • Workgroup on Hypoglycemia, American Diabetes Association. Defining and reporting hypoglycemia in diabetes: a report from the American Diabetes Association Workgroup on Hypoglycemia. Diabetes Care. 2005;28(5):1245-9.
    • (2005) Diabetes Care , vol.28 , Issue.5 , pp. 1245-1249
  • 48
    • 0023277685 scopus 로고
    • Influence of sympathetic nervous system on hypoglycaemic warning symptoms
    • Heller SR, Macdonald IA, Herbert M, Tattersall RB. Influence of sympathetic nervous system on hypoglycaemic warning symptoms. Lancet. 1987;2(8555):359-63.
    • (1987) Lancet , vol.2 , Issue.8555 , pp. 359-363
    • Heller, S.R.1    Macdonald, I.A.2    Herbert, M.3    Tattersall, R.B.4
  • 51
    • 26844470094 scopus 로고    scopus 로고
    • Current evidence regarding the value of self-monitored blood glucose testing
    • Blonde L, Karter AJ. Current evidence regarding the value of self-monitored blood glucose testing. Am J Med. 2005;118(Suppl 9A):20S-26S.
    • (2005) Am J Med. , vol.118 , Issue.SUPPL. 9A
    • Blonde, L.1    Karter, A.J.2
  • 52
    • 2642562011 scopus 로고    scopus 로고
    • Self-monitoring of blood glucose in diabetic patients: From the least common denominator to the greatest common multiple
    • Monnier L, Colette C, Lapinski H, Boniface H. Self-monitoring of blood glucose in diabetic patients: from the least common denominator to the greatest common multiple. Diabetes Metab. 2004;30(2):113-9.
    • (2004) Diabetes Metab. , vol.30 , Issue.2 , pp. 113-119
    • Monnier, L.1    Colette, C.2    Lapinski, H.3    Boniface, H.4
  • 54
    • 0031590552 scopus 로고    scopus 로고
    • Adherence to insulin treatment, glycaemic control, and ketoacidosis in insulin-dependent diabetes mellitus. The DARTS/MEMO Collaboration. Diabetes Audit and Research in Tayside Scotland. Medicines Monitoring Unit
    • Morris AD, Boyle DI, McMahon AD, Greene SA, MacDonald TM, Newton RW. Adherence to insulin treatment, glycaemic control, and ketoacidosis in insulin-dependent diabetes mellitus. The DARTS/MEMO Collaboration. Diabetes Audit and Research in Tayside Scotland. Medicines Monitoring Unit. Lancet. 1997;350(9090):1505-10.
    • (1997) Lancet , vol.350 , Issue.9090 , pp. 1505-1510
    • Morris, A.D.1    Boyle, D.I.2    McMahon, A.D.3    Greene, S.A.4    MacDonald, T.M.5    Newton, R.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.