Hyaluronic acid-bound letrozole nanoparticles restore sensitivity to letrozole-resistant xenograft tumors in mice

Journal of Nanoscience and Nanotechnology

Volumn 11, Issue 5, 2011, Pages 3789-3799

  Nair, Hareesh B ^a,c   Huffman, Steven ^a   Veerapaneni, Poornachand ^a   Kirma, Nameer B ^a   Binkley, Peter ^a   Perla, Rao P ^a   Evans, Dean B ^b   Tekmal, Rajeshwar R ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c SOUTHWEST NATIONAL PRIMATE RESEARCH CENTER   (United States)

Author keywords

Active targeting; Aromatase; Drug resistance; Hyaluronic acid; Letrozole; Nanoparticles

Indexed keywords

ACTIVE TARGETING; AROMATASE; DRUG RESISTANCE; HYALURONIC ACID; LETROZOLE;

BIODEGRADABLE POLYMERS; BIOLOGICAL MATERIALS; CALCIUM; CELL MEMBRANES; CYTOLOGY; ENZYME ACTIVITY; FLOW CYTOMETRY; MAMMALS; NANOPARTICLES; ORGANIC ACIDS; RESTORATION;

TUMORS;

ANTINEOPLASTIC AGENT; HYALURONIC ACID; LETROZOLE; NANOPARTICLE; NITRILE; TRIAZOLE DERIVATIVE;

ANIMAL; APOPTOSIS; ARTICLE; CHEMISTRY; DRUG EFFECT; DRUG RESISTANCE; DRUG SCREENING; FLOW CYTOMETRY; MOUSE; RNA INTERFERENCE; SCANNING ELECTRON MICROSCOPY; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; DRUG RESISTANCE, NEOPLASM; FLOW CYTOMETRY; HYALURONIC ACID; MICE; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; NITRILES; RNA INTERFERENCE; TRIAZOLES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 80051584497     PISSN: 15334880     EISSN: None     Source Type: Journal    
DOI: 10.1166/jnn.2011.3871     Document Type: Conference Paper

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