Developing a geographic search filter to identify randomised controlled trials in Africa: Finding the optimal balance between sensitivity and precision

Health Information and Libraries Journal

Volumn 28, Issue 3, 2011, Pages 210-215

  Pienaar, Elizabeth ^a   Grobler, Liesl ^a   Busgeeth, Karishma ^b   Eisinga, Anne ^c   Siegfried, Nandi ^a  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b Housing Development Agency   (South Africa)

^c UK COCHRANE CENTRE   (United Kingdom)

Author keywords

Bibliographic databases; Clinical trials; Health information needs; Indexing; Search strategies

Indexed keywords

AFRICA; ARTICLE; BIBLIOGRAPHIC DATABASE; DOCUMENTATION; GEOGRAPHY; HUMAN; INFORMATION DISSEMINATION; INTERNET; MEDLINE; METHODOLOGY; RANDOMIZED CONTROLLED TRIAL (TOPIC); REGISTER; STATISTICS;

ABSTRACTING AND INDEXING AS TOPIC; AFRICA; DATABASES, BIBLIOGRAPHIC; GEOGRAPHY; HUMANS; INFORMATION DISSEMINATION; INTERNET; PUBMED; RANDOMIZED CONTROLLED TRIALS AS TOPIC; REGISTRIES;

EID: 80051567478     PISSN: 14711834     EISSN: 14711842     Source Type: Journal    
DOI: 10.1111/j.1471-1842.2011.00936.x     Document Type: Article

References (19)

1. WHO. The WHO Registry Network. Accessible at.
2. White, V. J., Glanville, J. M., Lefebvre, C. & Sheldon, T. A. A statistical approach to designing search filters to find systematic reviews: objectivity enhances accuracy. Journal of Information Science 2001, 27, 357-370.
3. Glanville, J. M., Lefebvre, C., Miles, J. N. & Camosso-Stefinovic, J. How to identify randomized controlled trials in MEDLINE: ten years on. Journal of the Medical Library Association 2006, 94, 130-136.
4. Valderas, J. M., Mendivil, J., Parada, A., Losada-Yáñez, M. & Alonso, J. Development of a geographic filter for PubMed/MEDLINE to identify studies performed in Spain. Revista Espana Cardiologia 2006, 59, 1244-1251.
5. Eisinga, A., Siegfried, N. & Clarke, M. The sensitivity and precision of search terms in Phases I, II and III of the Cochrane Highly Sensitive Search Strategy for identifying reports of randomized trials in Medline in a specific area of health care - HIV/AIDS prevention and treatment interventions. Health Information Library Journal 2007, 24, 103-109.
6. Siegfried, N., Clarke, M. & Volmink, J. Randomized controlled trials in Africa of HIV and AIDS: descriptive study and spatial distribution. BMJ 2005, 331, 742-746.
7. Gottlieb, M. S., Schroff, R., Schanker, H. M., Weisman, J. D., Fan, P. T., Wolf, R. A. & Saxon, A. Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency. New England Journal of Medicine 1981, 305, 1425-1431.
8. Lefebvre, C., Manheimer, E. & Glanville, J. Chapter 6: Searching for studies. In: Higgins, J. P. T. & Green, S. (eds). Cochrane Handbook of Systematic Reviews of Interventions Version 5.0.0, (updated February 2008). The Cochrane Collaboration, 2008: 136-139. Accessible at.
9. Lefebvre, C., Eisinga, A., McDonald, S. & Paul, N. Enhancing access to reports of clinical trials published world-wide - the contribution of EMBASE records to the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library. Emerging Themes in Epidemiology 2008, 5, 13.
10. Jenkins, M. Evaluation of methodological search filters - a review. Health Information and Libraries Journal 2004, 21, 148-163.
11. Thompson, D. Geography of U.S. Biomedical publications. New England Journal of Medicine 1999, 340, 817-818.
12. Tadmouri, G. & Bissar-Tadmouri, N. Biomedical publications in an unstable region: the Arab world, 1998-2002. Lancet 2003, 362, 1766.
13. Edwards, P., Clarke, M., DiGuiseppi, C., Pratap, S., Roberts, I. & Wentz, R. Identification of randomized controlled trials in systematic reviews: accuracy and reliability of screening records. Statistics in Medicine 2002, 21, 1635-1640.
14. Sampson, M., Zhang, L., Morrison, A., Barrowman, N. J., Clifford, T. J., Platt, R. W., Klassen, T. P. & Moher, D. An alternative to the hand searching gold standard: validating methodological search filters using relative recall. BMC Medical Research Methodology 2006, 6, 33.
15. Shafi, S. M. & Rather, R. A. Precision and Recall of five search engines for retrieval of scholarly information in the field of Biotechnology. Webology 2005, 2(2), Article 12. Accessible at: (accessed 3 February 2009).
16. Ritchie, G., Glanville, J. & Lefebvre, C. Do published search filters to identify diagnostic test accuracy studies perform adequately? Health Information and Libraries Journal 2007, 24, 188-192.
17. Sim, I., Chan, A. W., Gulmezoglu, A. M., Evans, T. & Pang, T. Clinical trial registration: transparency is the watchword. Lancet 2006, 367, 1631-1633.
18. Grobler, L., Siegfried, N., Askie, L., Hooft, L., Tharyan, P. & Antes, G. National and multinational prospective trial registers. Lancet 2008, 372(9645), 1201-1202.
19. Abrams, A. & Siegfried, N. Maximising the effectiveness of trial registries in resource-constrained settings (Guest Editorial). Clinical Evidence 2009. Accessible at: (accessed 20 May 2010).