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Volumn 57, Issue 5, 2011, Pages 387-395

Early postseroconversion CD4 cell counts independently predict CD4 cell count recovery in HIV-1-postive subjects receiving antiretroviral therapy

(14)  Kulkarni, Hemant a,b   Okulicz, Jason F c,d   Grandits, Greg c,e   Crum Cianflone, Nancy F c,f   Landrum, Michael L c,d   Hale, Braden c,f   Wortmann, Glenn c,g   Tramont, Edmund c,h   Polis, Michael c,h   Dolan, Matthew i   Lifson, Alan R e   Agan, Brian K c   Ahuja, Sunil K a,b,j   Marconi, Vincent C c,k  


Author keywords

CD4 count; highly active antiretroviral therapy; outcomes; predictors; treatment response

Indexed keywords

ANTIRETROVIRUS AGENT;

EID: 80051550219     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0b013e3182219113     Document Type: Article
Times cited : (24)

References (45)
  • 1
    • 41149176926 scopus 로고    scopus 로고
    • Clinical outcome of HIV-infected antiretroviral-naive patients with discordant immunologic and virologic responses to highly active antiretroviral therapy
    • DOI 10.1097/QAI.0b013e31816856c5
    • Tan R, Westfall AO, Willig JH, et al. Clinical outcome of HIV-infected antiretroviral-naive patients with discordant immunologic and virologic responses to highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2008;47:553-558. (Pubitemid 351442024)
    • (2008) Journal of Acquired Immune Deficiency Syndromes , vol.47 , Issue.5 , pp. 553-558
    • Tan, R.1    Westfall, A.O.2    Willig, J.H.3    Mugavero, M.J.4    Saag, M.S.5    Kaslow, R.A.6    Kempf, M.C.7
  • 2
    • 0034687071 scopus 로고    scopus 로고
    • Clinical outcome of patients with HIV-1 infection according to immunologic and virologic response after 6 months of highly active antiretroviral therapy
    • Grabar S, Le Moing V, Goujard C, et al. Clinical outcome of patients with HIV-1 infection according to immunologic and virologic response after 6 months of highly active antiretroviral therapy. Ann Intern Med. 2000;133: 401-410.
    • (2000) Ann Intern Med. , vol.133 , pp. 401-410
    • Grabar, S.1    Le Moing, V.2    Goujard, C.3
  • 3
    • 65449125411 scopus 로고    scopus 로고
    • Discordant immunologic and virologic responses to antiretroviral therapy and associated mortality in a large treatment program in Rwanda
    • van Griensven J, Zachariah R, Rasschaert F, et al. Discordant immunologic and virologic responses to antiretroviral therapy and associated mortality in a large treatment program in Rwanda. J Acquir Immune Defic Syndr. 2009;50:556-558.
    • (2009) J Acquir Immune Defic Syndr. , vol.50 , pp. 556-558
    • Van Griensven, J.1    Zachariah, R.2    Rasschaert, F.3
  • 4
    • 33645036588 scopus 로고    scopus 로고
    • Disease progression in patients with virological suppression in response to HAART is associated with the degree of immunological response
    • Moore DM, Hogg RS, Chan K, et al. Disease progression in patients with virological suppression in response to HAART is associated with the degree of immunological response. AIDS. 2006;20:371-377.
    • (2006) AIDS. , vol.20 , pp. 371-377
    • Moore, D.M.1    Hogg, R.S.2    Chan, K.3
  • 5
    • 0037183954 scopus 로고    scopus 로고
    • Limited immune restoration after 3 years' suppression of HIV-1 replication in patients with moderately advanced disease
    • Valdez H, Connick E, Smith KY, et al. Limited immune restoration after 3 years' suppression of HIV-1 replication in patients with moderately advanced disease. AIDS. 2002;16:1859-1866.
    • (2002) AIDS. , vol.16 , pp. 1859-1866
    • Valdez, H.1    Connick, E.2    Smith, K.Y.3
  • 6
    • 27444439823 scopus 로고    scopus 로고
    • Discordant immunologic and virologic responses to highly active antiretroviral therapy are associated with increased mortality and poor adherence to therapy
    • DOI 10.1097/01.qai.0000182847.38098.d1
    • Moore DM, Hogg RS, Yip B, et al. Discordant immunologic and virologic responses to highly active antiretroviral therapy are associated with increased mortality and poor adherence to therapy. J Acquir Immune Defic Syndr. 2005;40:288-293. (Pubitemid 41533068)
    • (2005) Journal of Acquired Immune Deficiency Syndromes , vol.40 , Issue.3 , pp. 288-293
    • Moore, D.M.1    Hogg, R.S.2    Yip, B.3    Wood, E.4    Tyndall, M.5    Braitstein, P.6    Montaner, J.S.G.7
  • 8
    • 77954762074 scopus 로고    scopus 로고
    • Immunodeficiency and the risk of serious clinical endpoints in a well studied cohort of treated HIV-infected patients
    • Achhra AC, Amin J, Law MG, et al. Immunodeficiency and the risk of serious clinical endpoints in a well studied cohort of treated HIV-infected patients. AIDS. 2010;24:1877-1886.
    • (2010) AIDS. , vol.24 , pp. 1877-1886
    • Achhra, A.C.1    Amin, J.2    Law, M.G.3
  • 10
    • 15444362420 scopus 로고    scopus 로고
    • 6 cells/l
    • Mussini C, Bedini A, Borghi V, et al. CD4 cell-monitored treatment interruption in patients with a CD4 cell count . 500 x 106 cells/l. AIDS. 2005;19:287-294. (Pubitemid 40396560)
    • (2005) AIDS , vol.19 , Issue.3 , pp. 287-294
    • Mussini, C.1
  • 12
    • 0035941382 scopus 로고    scopus 로고
    • HIV-1 RNA, CD4 T-lymphocytes, and clinical response to highly active antiretroviral therapy
    • DOI 10.1097/00002030-200111230-00006
    • Sterling TR, Chaisson RE, Moore RD. HIV-1 RNA, CD4 T-lymphocytes, and clinical response to highly active antiretroviral therapy. AIDS. 2001; 15:2251-2257. (Pubitemid 34059832)
    • (2001) AIDS , vol.15 , Issue.17 , pp. 2251-2257
    • Sterling, T.R.1    Chaisson, R.E.2    Moore, R.D.3
  • 14
    • 0037163476 scopus 로고    scopus 로고
    • Risk of progression to AIDS and death in women infected with HIV-1 initiating highly active antiretroviral treatment at different stages of disease
    • Anastos K, Barron Y, Miotti P, et al. Risk of progression to AIDS and death in women infected with HIV-1 initiating highly active antiretroviral treatment at different stages of disease. Arch Intern Med. 2002;162: 1973-1980.
    • (2002) Arch Intern Med. , vol.162 , pp. 1973-1980
    • Anastos, K.1    Barron, Y.2    Miotti, P.3
  • 17
    • 65449167169 scopus 로고    scopus 로고
    • Effect of early versus deferred antiretroviral therapy for HIV on survival
    • Kitahata MM, Gange SJ, Abraham AG, et al. Effect of early versus deferred antiretroviral therapy for HIV on survival. N Engl J Med. 2009; 360:1815-1826.
    • (2009) N Engl J Med. , vol.360 , pp. 1815-1826
    • Kitahata, M.M.1    Gange, S.J.2    Abraham, A.G.3
  • 19
    • 0034119250 scopus 로고    scopus 로고
    • Long-term immunological response in HIV-1-infected subjects receiving potent antiretroviral therapy
    • DOI 10.1097/00002030-200005260-00007
    • Kaufmann GR, Bloch M, Zaunders JJ, et al. Long-term immunological response in HIV-1-infected subjects receiving potent antiretroviral therapy. AIDS. 2000;14:959-969. (Pubitemid 30336056)
    • (2000) AIDS , vol.14 , Issue.8 , pp. 959-969
    • Kaufmann, G.R.1    Bloch, M.2    Zaunders, J.J.3    Smith, D.4    Cooper, D.A.5
  • 22
    • 58749093399 scopus 로고    scopus 로고
    • Incomplete reconstitution of T cell subsets on combination antiretroviral therapy in the AIDS Clinical Trials Group protocol 384
    • Robbins GK, Spritzler JG, Chan ES, et al. Incomplete reconstitution of T cell subsets on combination antiretroviral therapy in the AIDS Clinical Trials Group protocol 384. Clin Infect Dis. 2009;48: 350-361.
    • (2009) Clin Infect Dis. , vol.48 , pp. 350-361
    • Robbins, G.K.1    Spritzler, J.G.2    Chan, E.S.3
  • 23
    • 0037084272 scopus 로고    scopus 로고
    • The extent of HIV-1-related immunodeficiency and age predict the long-term CD4 T lymphocyte response to potent antiretroviral therapy
    • DOI 10.1097/00002030-200202150-00007
    • Kaufmann GR, Bloch M, Finlayson R, et al. The extent of HIV-1-related immunodeficiency and age predict the long-term CD4 T lymphocyte response to potent antiretroviral therapy. Aids. 2002;16:359-367. (Pubitemid 34165367)
    • (2002) AIDS , vol.16 , Issue.3 , pp. 359-367
    • Kaufmann, G.R.1    Bloch, M.2    Finlayson, R.3    Zaunders, J.4    Smith, D.5    Cooper, D.A.6
  • 25
    • 33846439783 scopus 로고    scopus 로고
    • + cell count 6 years after commencement of highly active antiretroviral therapy in persons with sustained virologic suppression
    • DOI 10.1086/510746
    • Moore RD, Keruly JC. CD4+ cell count 6 years after commencement of highly active antiretroviral therapy in persons with sustained virologic suppression. Clin Infect Dis. 2007;44:441-446. (Pubitemid 46147630)
    • (2007) Clinical Infectious Diseases , vol.44 , Issue.3 , pp. 441-446
    • Moore, R.D.1    Keruly, J.C.2
  • 26
    • 0034809303 scopus 로고    scopus 로고
    • + cell kinetic patterns and their relationships with baseline factors and virological responses in HIV type 1 patients receiving highly active antiretroviral therapy
    • DOI 10.1089/088922201750461285
    • Wu H, Connick E, Kuritzkes DR, et al. Multiple CD4+ cell kinetic patterns and their relationships with baseline factors and virological responses in HIV type 1 patients receiving highly active antiretroviral therapy. AIDS Res Hum Retroviruses. 2001;17:1231-1240. (Pubitemid 32911626)
    • (2001) AIDS Research and Human Retroviruses , vol.17 , Issue.13 , pp. 1231-1240
    • Wu, H.1    Connick, E.2    Kuritzkes, D.R.3    Landay, A.4    Spritzler, J.5    Zhang, B.6    Spear, G.T.7    Kessler, H.8    Lederman, M.M.9
  • 30
    • 73349126759 scopus 로고    scopus 로고
    • Virologic response differences between African Americans and European Americans initiating highly active antiretroviral therapy with equal access to care
    • Weintrob AC, Grandits GA, Agan BK, et al. Virologic response differences between African Americans and European Americans initiating highly active antiretroviral therapy with equal access to care. J Acquir Immune Defic Syndr. 2009;52:574-580.
    • (2009) J Acquir Immune Defic Syndr. , vol.52 , pp. 574-580
    • Weintrob, A.C.1    Grandits, G.A.2    Agan, B.K.3
  • 31
    • 77952737410 scopus 로고    scopus 로고
    • Outcomes of highly active antiretroviral therapy in the context of universal access to healthcare: The U.S. Military HIV Natural History Study
    • Marconi VC, Grandits GA, Weintrob AC, et al. Outcomes of highly active antiretroviral therapy in the context of universal access to healthcare: the U.S. Military HIV Natural History Study. AIDS Res Ther. 2010;7:14.
    • (2010) AIDS Res Ther , vol.7 , pp. 14
    • Marconi, V.C.1    Grandits, G.A.2    Weintrob, A.C.3
  • 32
    • 79956328148 scopus 로고    scopus 로고
    • 2011 Cumulative viral load and virologic decay patterns after antiretroviral therapy in hiv-infected subjects influence CD4 Recovery and AIDS
    • Marconi VC, Grandits G, Okulicz JF, et al. 2011 Cumulative Viral Load and Virologic Decay Patterns after Antiretroviral Therapy in HIV-Infected Subjects Influence CD4 Recovery and AIDS. PLoS ONE. 2011;6:17956.
    • (2011) PLoS ONE. , vol.6 , pp. 17956
    • Marconi, V.C.1    Grandits, G.2    Okulicz, J.F.3
  • 34
    • 0027913313 scopus 로고
    • Revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults
    • From the Centers for Disease Control and Prevention
    • From the Centers for Disease Control and Prevention. 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. JAMA. 1993;269: 729-730.
    • (1993) JAMA. , vol.269 , pp. 729-730
  • 35
    • 58749087048 scopus 로고    scopus 로고
    • The absence of CD4+ T cell count recovery despite receipt of virologically suppressive highly active antiretroviral therapy: Clinical risk, immunological gaps, and therapeutic options
    • Gazzola L, Tincati C, Bellistri GM, et al. The absence of CD4+ T cell count recovery despite receipt of virologically suppressive highly active antiretroviral therapy: clinical risk, immunological gaps, and therapeutic options. Clin Infect Dis. 2009;48:328-337.
    • (2009) Clin Infect Dis. , vol.48 , pp. 328-337
    • Gazzola, L.1    Tincati, C.2    Bellistri, G.M.3
  • 39
    • 33646052566 scopus 로고    scopus 로고
    • Immunological recovery and antiretroviral therapy in HIV-1 infection
    • Battegay M, Nuesch R, Hirschel B, et al. Immunological recovery and antiretroviral therapy in HIV-1 infection. Lancet Infect Dis. 2006;6:280-287.
    • (2006) Lancet Infect Dis. , vol.6 , pp. 280-287
    • Battegay, M.1    Nuesch, R.2    Hirschel, B.3
  • 40
    • 77951680634 scopus 로고    scopus 로고
    • Measurement of naive CD4 cells reliably predicts potential for immune reconstitution in HIV
    • Schacker TW, Bosch RJ, Bennett K, et al. Measurement of naive CD4 cells reliably predicts potential for immune reconstitution in HIV. J Acquir Immune Defic Syndr. 2010;54:59-62.
    • (2010) J Acquir Immune Defic Syndr. , vol.54 , pp. 59-62
    • Schacker, T.W.1    Bosch, R.J.2    Bennett, K.3
  • 41
    • 77953901782 scopus 로고    scopus 로고
    • Nonprogressive and progressive primate immunodeficiency lentivirus infections
    • Brenchley JM, SilvestriG, Douek DC. Nonprogressive and progressive primate immunodeficiency lentivirus infections. Immunity. 2010;32:737-742.
    • (2010) Immunity. , vol.32 , pp. 737-742
    • Brenchley, J.M.1    Silvestri, G.2    Douek, D.C.3
  • 43
    • 0031964216 scopus 로고    scopus 로고
    • Contribution of CD4+, CD8+CD28+, and CD8+CD28-T cells to CD3+ lymphocyte homeostasis during the natural course of HIV-1 infection
    • Caruso A, Licenziati S, Canaris AD, et al. Contribution of CD4+, CD8+CD28+, and CD8+CD28-T cells to CD3+ lymphocyte homeostasis during the natural course of HIV-1 infection. J Clin Invest. 1998;101: 137-144.
    • (1998) J Clin Invest. , vol.101 , pp. 137-144
    • Caruso, A.1    Licenziati, S.2    Canaris, A.D.3
  • 44
    • 0030249833 scopus 로고    scopus 로고
    • CD4:CD8 ratio and HIV infection: The 'tap-and-drain' hypothesis
    • DOI 10.1016/0167-5699(96)10049-9
    • Amadori A, Zamarchi R, Chieco-Bianchi L. CD4: CD8 ratio and HIV infection: the "tap-and-drain" hypothesis. Immunol Today. 1996;17: 414-417. (Pubitemid 26278365)
    • (1996) Immunology Today , vol.17 , Issue.9 , pp. 414-417
    • Amadori, A.1    Zamarchi, R.2    Chieco-Bianchi, L.3
  • 45
    • 78651443087 scopus 로고    scopus 로고
    • Long-term CD4+ lymphocyte response following HAART initiation in a U.S. Military prospective cohort
    • Lifson AR, Krantz EM, Eberly LE, et al. Long-term CD4+ lymphocyte response following HAART initiation in a U.S. Military prospective cohort. AIDS Res Ther. 2011;8:2.
    • (2011) AIDS Res Ther. , vol.8 , pp. 2
    • Lifson, A.R.1    Krantz, E.M.2    Eberly, L.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.