Pd-catalysed direct 5-arylation of 1-methylpyrazole with aryl bromides

Synthesis

Volumn , Issue 16, 2011, Pages 2553-2560

  Beladhria, Anissa ^a,b   Beydoun, Kassem ^b   Ammar, Hamed Ben ^a   Salem, Ridha Ben ^c   Doucet, Henri ^b  

^a UNIVERSITY OF GABES   (Tunisia)

^b UMR 6509 Organometalliques et Catalyse Chimie et Electrochimie Moleculaires   (France)

^c UNIVERSITY OF SFAX   (Tunisia)

Author keywords

arylation; coupling; palladium; pyrazoles; regioselectivity

Indexed keywords

ARYL BROMIDES; ARYLATIONS; C-H ACTIVATION; COUPLING PRODUCT; ELECTRON-RICH; HIGH SELECTIVITY; PALLADIUM ACETATE; POTASSIUM ACETATE; PYRAZOLES; REACTION CONDITIONS; STERIC PROPERTIES;

AROMATIC COMPOUNDS; BROMINE COMPOUNDS; CATALYSIS; METAL HALIDES; ORGANOMETALLICS; PALLADIUM COMPOUNDS; POTASSIUM; VOLATILE FATTY ACIDS;

CATALYST SELECTIVITY;

1 [3 (2 METHYLPYRAZOL 3 YL)PHENYL]ETHANONE; 1 [4 (2 METHYLPYRAZOL 3 YL)PHENYL]ETHANONE; 1 [4 (2 METHYLPYRAZOL 3 YL)PHENYL]PROPAN 1 ONE; 1 METHYL 4,5 BIS[(4 CYANOPHENYL)]PYRAZOLE; 1 METHYL 5 (4 NITROPHENYL)PYRAZOLE; 1 METHYL 5 NAPHTHALEN 1 YLPYRAZOLE; 1 METHYL 5 NAPHTHALEN 2 YLPYRAZOLE; 1 METHYLPYRAZOLE; 2 (2 METHYLPYRAZOL 3 YL)BENZALDEHYDE; 3 (2 METHYLPYRAZOL 3 YL)BENZALDEHYDE; 3 (2 METHYLPYRAZOL 3 YL)BENZONITRILE; 3 (2 METHYLPYRAZOL 3 YL)PYRIDINE; 3 (2 METHYLPYRAZOL 3 YL)QUINOLINE; 4 (1 METHYLPYRAZOL 4 YL)BENZONITRILE; 4 (2 METHYLPYRAZOL 3 YL)BENZALDEHYDE; 4 (2 METHYLPYRAZOL 3 YL)BENZONITRILE; 4 (2 METHYLPYRAZOL 3 YL)ISOQUINOLINE; 5 (2 METHYLPYRAZOL 3 YL)PYRIMIDINE; 5 (4 METHOXYPHENYL) 1 METHYLPYRAZOLE; 5 (6 METHOXYNAPHTHALEN 2 YL) 1 METHYLPYRAZOLE; 5 ANTHRACEN 9 YL 1 METHYLPYRAZOLE; [4 (2 METHYLPYRAZOL 3 YL)PHENYL]PHENYLMETHANONE; ACETIC ACID; ARYL BROMIDE DERIVATIVE; BENZONITRILE; BROMINE DERIVATIVE; METHYL 4 (2 METHYLPYRAZOL 3 YL)BENZOATE; PALLADIUM ACETATE; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; CATALYSIS; CATALYST; CHEMICAL BINDING; CHEMICAL INTERACTION; CHEMICAL MODIFICATION; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; CONTROLLED STUDY; CROSS COUPLING REACTION; SOLVENT EFFECT; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

EID: 80051546994     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1260076     Document Type: Article

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