Development and validation of a reversed-phase HPLC method for determination of lesatropane and enantiomeric impurity

Chirality

Volumn 23, Issue 8, 2011, Pages 581-584

  Yang, Li Min ^a   Xie, Yi Fan ^a   Gu, Zhou Hui ^b   Wang, Ai Ling ^b   Chen, Hong Zhuan ^a   Lu, Yang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Shanghai PharmValley Corp   (China)

Author keywords

amylose based chiral stationary phase; enantiomeric separation; lesatropane; muscarinic agonist

Indexed keywords

ACETONITRILE; DESATROPANE; HYDROGEN; LESATROPANE; MUSCARINIC AGENT; POTASSIUM; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CHIRALITY; DRUG STRUCTURE; ENANTIOMER; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; VALIDATION STUDY;

AMYLOSE; CARBAMATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; MUSCARINIC AGONISTS; PHENYLCARBAMATES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; TROPANES;

EID: 80051546321     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20971     Document Type: Article

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