Polymorphisms of VEGFA gene and susceptibility to hemorrhage risk of brain arteriovenous malformations in a Chinese population

Acta Pharmacologica Sinica

Volumn 32, Issue 8, 2011, Pages 1071-1077

  Gong, Zhi Ping ^a   Qiao, Ni Dan ^b   Gu, Yu Xiang ^b   Song, Jian Ping ^b   Li, Pei Liang ^b   Qiu, Hui Jia ^b   Fan, Wei Wei ^c   Mao, Ying ^b   Chen, Hong Yan ^c   Zhao, Yao ^b  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b FUDAN UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

brain arteriovenous malformations; cerebral hemorrhage; single nucleotide polymorphism (SNPs); vascular endothelial growth factor A (VEGFA)

Indexed keywords

VASCULOTROPIN A;

ADULT; ARTICLE; BRAIN ARTERIOVENOUS MALFORMATION; BRAIN HEMORRHAGE; BRAIN SCINTIANGIOGRAPHY; CHINESE; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ARTERIOVENOUS FISTULA; ASIAN CONTINENTAL ANCESTRY GROUP; CEREBRAL HEMORRHAGE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 80051535239     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.76     Document Type: Article

References (32)

1. Arteriovenous Malformation Study Group. Arteriovenous malformations of the brain in adults. N Engl J Med 1999; 340: 1812-8.
2. Pawlikowska L, Tran MN, Achrol AS, McCulloch CE, Ha C, Lind DL, et al. UCSF BAVM Study Project: Polymorphisms in genes involved in inflammatory and angiogenic pathways and the risk of hemorrhagic presentation of brain arteriovenous malformations. Stroke 2004; 35: 2294-300.
3. Connolly DT, Heuvelman DM, Nelson R, Olander JV, Eppley BL, Delfino JJ, et al. Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 1989; 84: 1470-8. (Pubitemid 19272234)
4. Ferrara N, Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr Rev 1997; 18: 4-25. (Pubitemid 27076453)
5. Ferrara N. Role of vascular endothelial growth factor in regulation of physiological angiogenesis. Am J Physiol Cell Physiol 2001; 280: C1358-66. (Pubitemid 32553190)
6. Bates DO, Harper SJ. Regulation of vascular permeability by vascular endothelial growth factors. Vascul Pharmacol 2002; 39: 225-37. (Pubitemid 37490748)
7. Ferrara N. Vascular endothelial growth factor as a target for anticancer therapy. Oncologist 2004; 9: 2-10. (Pubitemid 38747842)
8. Hashimoto T, Lawton MT, Wen G, Yang GY, Chaly T Jr, Stewart CL, et al. Gene microarray analysis of human brain arteriovenous malformations. Neurosurgery 2004; 54: 410-23.
9. Lee CZ, Xue Z, Zhu Y, Yang GY, Young WL. Matrix metalloproteinase-9 inhibition attenuates vascular endothelial growth factor-induced intracranial hemorrhage. Stroke 2007; 38: 2563-8. (Pubitemid 47329638)
10. Sfar S, Hassen E, Saad H, Mosbah F, Chouchane L. Association of VEGF genetic polymorphisms with prostate carcinoma risk and clinical outcome. Cytokine 2006; 35: 21-8. (Pubitemid 44485531)
11. Howell WM, Bateman AC, Turner SJ, Collins A, Theaker JM. Influence of vascular endothelial growth factor single nucleotide polymorphisms on tumour development in cutaneous malignant melanoma. Genes Immun 2002; 3: 229-32. (Pubitemid 38961136)
12. Kataoka N, Cai Q, Wen W, Shu XO, Jin F, Gao YT, et al. Populationbased case-control study of VEGF gene polymorphisms and breast cancer risk among Chinese women. Cancer Epidemiol Biomarkers Prev 2006; 15: 1148-52.
13. Lee SJ, Lee SY, Jeon HS, Park SH, Jang JS, Lee GY, et al. Vascular endothelial growth factor gene polymorphisms and risk of primary lung cancer. Cancer Epidemiol Biomarkers Prev 2005; 14: 571-5. (Pubitemid 40489197)
14. Awata T, Inoue K, Kurihara S, Ohkubo T, Watanabe M, Inukai K, et al. A common polymorphism in the 5'-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes. Diabetes 2002; 51: 1635-9. (Pubitemid 34826636)
15. Vannay A, Dunai G, Bányász I, Szabó M, Vámos R, Treszl A, et al. Association of genetic polymorphisms of vascular endothelial growth factor and risk for proliferative retinopathy of prematurity. Paediatr Res 2005; 57: 396-8. (Pubitemid 40293607)
16. Chen HY, Gu YX, Wu WT, Chen D, Li PL, Fan WW, et al. Vascular endothelial growth factor A gene polymorphisms and susceptibility to sporadic brain arteriovenous malformations in a Chinese population. J Clin Neurosci 2011; 18: 549-53.
17. Joint Writing Group of the Technology Assessment Committee American Society of Interventional and Therapeutic Neuroradiology; Joint Section on Cerebrovascular Neurosurgery a Section of the American Association of Neurological Surgeons and Congress of Neurological Surgeons; Section of Stroke and the Section of Interventional Neurology of the American Academy of Neurology, Atkinson RP, Awad IA, Batjer HH, Dowd CF, Furlan A, Giannotta SL, et al. Reporting terminology for brain arteriovenous malformation clinical and radiographic features for use in clinical trials. Stroke 2001; 32: 1430-42.
18. Jurinke C, van den Boom D, Cantor CR, Koster H. Automated genotyping using the DNA MassArray technology. Methods Mol Biol 2002; 187: 179-92.
19. Akaike H. A new look at the statistical model identification. IEEE Trans Automat Contr 1974; 19: 716-23.
20. Lewontin RC. On measures of gametic disequilibrium. Genetics 1988; 120: 849-52. (Pubitemid 18260517)
21. Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, et al. The structure of haplotype blocks in the human genome. Science 2002; 296: 2225-9. (Pubitemid 34680308)
22. Stephens M, Donnelly P. A comparison of Bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 2003; 73: 1162-9. (Pubitemid 37414228)
23. Jung S, Moon KS, Jung TY, Kim IY, Lee YH, Rhu HH, et al. Possible pathophysiological role of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) in metastatic brain tumorassociated intracerebral hemorrhage. J Neurooncol 2006; 76: 257-63.
24. García-Closas M, Malats N, Real FX, Yeager M, Welch R, Silverman D, et al. Large-scale evaluation of candidate genes identifies associations between VEGF polymorphisms and bladder cancer risk. PLoS Genet 2007; 3: E29.
25. Churchill AJ, Carter JG, Lovell HC, Ramsden C, Turner SJ, Yeung A, et al. VEGF polymorphisms are associated with neovascular age-related macular degeneration. Hum Mol Genet 2006; 15: 2955-61. (Pubitemid 44446814)
26. Al-Kateb H, Mirea L, Xie X, Sun L, Liu M, Chen H, et al. Multiple variants in vascular endothelial growth factor (VEGFA) are risk factors for time to severe retinopathy in type 1 diabetes: The DCCT/EDIC genetics study. Diabetes 2007; 56: 2161-8. (Pubitemid 47195838)
27. Yuan HY, Chiou JJ, Tseng WH, Liu CH, Liu CK, Lin YJ, et al. FASTSNP: An always up-to-date and extendable service for SNP function analysis and prioritization. Nucleic Acids Res 2006; 34: W635-41.
28. Clark AG. The role of haplotypes in candidate gene studies. Genet Epidemiol 2004; 27: 321-33. (Pubitemid 39602317)
29. Han SW, Kim GW, Seo JS, Kim SJ, Sa KH, Park JY, et al. VEGF gene polymorphisms and susceptibility to rheumatoid arthritis. Rheumatology (Oxford) 2004; 43: 1173-7. (Pubitemid 39232824)
30. Churchill AJ, Carter JG, Lovell HC, Ramsden C, Turner SJ, Yeung A, et al. VEGF polymorphisms are associated with neovascular age-related macular degeneration. Hum Mol Genet 2006; 15: 2955-61. (Pubitemid 44446814)
31. Churchill AJ, Carter JG, Ramsden C, Turner SJ, Yeung A, Brenchley PE, et al. VEGF polymorphisms are associated with severity of diabetic retinopathy. Invest Ophthalmol Vis Sci 2008; 49: 3611-6.
32. Tsai SJ, Hong CJ, Liou YJ, Chen TJ, Chen ML, Hou SJ, et al. Haplotype analysis of single nucleotide polymorphisms in the vascular endothelial growth factor (VEGFA) gene and antidepressant treatment response in major depressive disorder. Psychiatry Res 2009; 169: 113-7.