Aristolochic acid induces apoptosis of human umbilical vein endothelial cells in vitro by suppressing PI3K/Akt signaling pathway

Acta Pharmacologica Sinica

Volumn 32, Issue 8, 2011, Pages 1025-1030

  Shi, Hong ^a,b   Feng, Jiang Min ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b Second Hospital of Fushun   (China)

Author keywords

apoptosis; aristolochic acid; HUVECs; PI3K Akt signaling pathway

Indexed keywords

ARISTOLOCHIC ACID; CASPASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL LEVEL; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; ARISTOLOCHIC ACIDS; CELLS, CULTURED; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 80051534535     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.74     Document Type: Article

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