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Volumn 12, Issue 13, 2011, Pages 2089-2095

Tranexamic acid therapy for heavy menstrual bleeding

Author keywords

antifibrinolytic; heavy menstrual bleeding; menorrhagia; tranexamic acid

Indexed keywords

CYKLO F; DESMOPRESSIN; DICLOFENAC; ETAMSYLATE; FLURBIPROFEN; GESTAGEN; GONADORELIN DERIVATIVE; LEVONORGESTREL; LYSTEDA; MEFENAMIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; NORETHISTERONE; ORAL CONTRACEPTIVE AGENT; PLACEBO; PLASMA PROTEIN; PLASMINOGEN; TISSUE PLASMINOGEN ACTIVATOR; TRANEXAMIC ACID; UNCLASSIFIED DRUG;

EID: 80051501954     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1517/14656566.2011.598857     Document Type: Review
Times cited : (24)

References (37)
  • 1
    • 84857106815 scopus 로고    scopus 로고
    • National Collaborating Centre for Women's and Children's Health. Heavy Menstrual Bleeding. London: RCOG Press; Available from
    • National Collaborating Centre for Women's and Children's Health. Heavy Menstrual Bleeding. London: RCOG Press; 2007. Available from: Http://guidance.nice.org.uk/CG44
    • (2007)
  • 2
    • 0344456368 scopus 로고
    • Hysterectomy-why and when?
    • In: Smith SK. editor. Royal Society of Medicine Press; London
    • Smith SK, Smith SK. Hysterectomy-why and when? In: Smith SK. editor. Dysfunctional uterine bleeding. Royal Society of Medicine Press; London: 1994. p. 107
    • (1994) Dysfunctional Uterine Bleeding , pp. 107
    • Smith, S.K.1    Smith, S.K.2
  • 5
    • 80051524562 scopus 로고    scopus 로고
    • Heavy menstrual bleeding
    • Mahmood T Templeton A Dhillon C. editors. RCOG Press; London
    • Wedisinghe L, Lumsden MA. Heavy Menstrual Bleeding. In: Mahmood T, Templeton A, Dhillon C. editors. Models of Care in Women's Health. RCOG Press; London: 2009. p. 67-80
    • (2009) Models of Care in Women's Health , pp. 67-80
    • Wedisinghe, L.1    Lumsden, M.A.2
  • 6
    • 80051514633 scopus 로고    scopus 로고
    • British National Formulary. (Volume 61). BMJ Publishing Group Ltd and RPS Publishing, London; 2011
    • British National Formulary. (Volume 61). BMJ Publishing Group Ltd and RPS Publishing, London; 2011
  • 7
    • 0029115483 scopus 로고
    • Menorrhagia in primary care: An overview of drug trials and a survey of prescribing practice
    • Coulter A, Kelland J, Peto V, Rees MC. Menorrhagia in primary care: An overview of drug trials and a survey of prescribing practice. Int J Technol Assess Health Care 1995;11(3):456-71
    • (1995) Int J Technol Assess Health Care , vol.11 , Issue.3 , pp. 456-471
    • Coulter, A.1    Kelland, J.2    Peto, V.3    Rees, M.C.4
  • 8
    • 0038121437 scopus 로고    scopus 로고
    • Tranexamic acid: A review of its use in the management of menorrhagia
    • DOI 10.2165/00003495-200363130-00008
    • Wellington K, Wagstaff AJ. Tranexamic acid: A review of its use in the management of menorrhagia. Drugs 2003;63(13):1417-33 (Pubitemid 36776096)
    • (2003) Drugs , vol.63 , Issue.13 , pp. 1417-1433
    • Wellington, K.1    Wagstaff, A.J.2
  • 9
    • 0016742118 scopus 로고
    • Differences in the binding to fibrin of native plasminogen and plasminogen modified by proteolytic degredation: Influence of omega-aminocarboxylic acids
    • Thorsen S. Differences in the binding to fibrin of native plasminogen and plasminogen modified by proteolytic degredation: Influence of omega-aminocarboxylic acids. Biochim Biophys Acta 1975;393:55-65
    • (1975) Biochim Biophys Acta , vol.393 , pp. 55-65
    • Thorsen, S.1
  • 10
    • 0028280082 scopus 로고
    • The effect of tranexamic acid on measured menstrual loss and endometrial fibrinolytic enzymes in dysfunctional uterine bleeding
    • Gleeson NC, Buggy F, Sheppard BL, et al. The effect of tranexamic acid on measured menstrual loss and endometrial fibrinolytic enzymes in dysfunctional uterine bleeding. Acta Obstet Gynecol Scand 1994;73:274-7 (Pubitemid 24074449)
    • (1994) Acta Obstetricia et Gynecologica Scandinavica , vol.73 , Issue.3 , pp. 274-277
    • Gleeson, N.C.1    Buggy, F.2    Sheppard, B.L.3    Bonnar, J.4
  • 12
    • 0026521847 scopus 로고
    • Vaginal absorption of low-dose tranexamic acid from impregnated tampons
    • Moodley J, Cohen M, Devraj K, Dutton M. Vaginal absorption of low-dose tranexamic acid from impregnated tampons. S Afr Med J 1992;81(3):150-2
    • (1992) S Afr Med J , vol.81 , Issue.3 , pp. 150-152
    • Moodley, J.1    Cohen, M.2    Devraj, K.3    Dutton, M.4
  • 13
    • 80051531268 scopus 로고
    • The biological availability of Cyklokapron solution administered orally
    • Stockholm
    • Eriksson O, Kjellman H, Schannong M. The biological availability of Cyklokapron solution administered orally. Data on file, Kabi AB; Stockholm: 1971
    • (1971) Data on file Kabi AB
    • Eriksson, O.1    Kjellman, H.2    Schannong, M.3
  • 14
    • 0021954364 scopus 로고
    • Clinical application of inhibitors of fibrinolysis
    • Verstraete M. Clinical application of inhibitors of fibrinolysis. Drugs 1985;29(3):236-61 (Pubitemid 15144749)
    • (1985) Drugs , vol.29 , Issue.3 , pp. 236-261
    • Verstraete, M.1
  • 15
    • 0029810706 scopus 로고    scopus 로고
    • Treatment of menorrhagia during menstruation: Randomised controlled trial of ethamsylate, mefenamic acid, and tranexamic acid
    • Bonnar J, Sheppard BL. Treatment of menorrhagia during menstruation: Randomised controlled trial of ethamsylate, mefenamic acid, and tranexamic acid. BMJ 1996;313:579-82 (Pubitemid 26293640)
    • (1996) British Medical Journal , vol.313 , Issue.7057 , pp. 579-582
    • Bonnar, J.1    Sheppard, B.L.2
  • 16
    • 0029007803 scopus 로고
    • Comparative study of tranexamic acid and norethisterone in the treatment of ovulatory menorrhagia
    • Preston JT, Cameron IT, Adams EJ, et al. Comparative study of tranexamic acid and norethisterone in the treatment of ovulatory menorrhagia. Br J Obstet Gynaecol 1995;102(5):401-6
    • (1995) Br J Obstet Gynaecol , vol.102 , Issue.5 , pp. 401-406
    • Preston, J.T.1    Cameron, I.T.2    Adams, E.J.3
  • 17
    • 0026022001 scopus 로고
    • A comparison of flurbiprofen, tranexamic acid, and a levonorgestrel- releasing intrauterine contraceptive device in the treatment of idiopathic menorrhagia
    • Milsom I, Andersson K, Andersch B, et al. A comparison of flurbiprofen, tranexamic acid, and a levonorgestrel-releasing intrauterine contraceptive device in the treatment of idiopathic menorrhagia. Am J Obstet Gynecol 1991;164(3):879-83
    • (1991) Am J Obstet Gynecol , vol.164 , Issue.3 , pp. 879-883
    • Milsom, I.1    Andersson, K.2    Andersch, B.3
  • 18
    • 0014960908 scopus 로고
    • Treatment of menorrhagia with tranexamic acid: A double-blind trial
    • Callender ST, Warner GT, Cope E. Treatment of menorrhagia with tranexamic acid: A double-blind trial. BMJ 1970;4(729):214-16
    • (1970) BMJ , vol.4 , Issue.729 , pp. 214-216
    • Callender, S.T.1    Warner, G.T.2    Cope, E.3
  • 19
    • 0020684634 scopus 로고
    • Comparison between antifibrinolytic and antiprostaglandin treatment in the reduction of increased menstrual blood loss in women with intrauterine contraceptive devices
    • Ylikorkala O, Viinikka L. Comparison between antifibrinolytic and antiprostaglandin treatment in the reduction of increased menstrual blood loss in women with intrauterine contraceptive devices. Br J Obstet Gynaecol 1983;90(1):78-83 (Pubitemid 13224187)
    • (1983) British Journal of Obstetrics and Gynaecology , vol.90 , Issue.1 , pp. 78-83
    • Ylikorkala, O.1    Viinikka, L.2
  • 20
    • 34848893679 scopus 로고    scopus 로고
    • Treatment of idiopathic menorrhagia with tranexamic acid
    • Srinil S, Jaisamrarn U. Treatment of idiopathic menorrhagia with tranexamic acid. J Med Assoc Thai 2005;88(2):S1-6
    • (2005) J Med Assoc Thai , vol.88 , Issue.2
    • Srinil, S.1    Jaisamrarn, U.2
  • 21
    • 63149155008 scopus 로고    scopus 로고
    • Multisite management study of menorrhagia with abnormal laboratory haemostasis: A prospective crossover study of intranasal desmopressin and oral tranexamic acid
    • Kouides PA, Byams VR, Philipp CS, et al. Multisite management study of menorrhagia with abnormal laboratory haemostasis: A prospective crossover study of intranasal desmopressin and oral tranexamic acid. Br J Haematol 2009;145(2):212-20
    • (2009) Br J Haematol , vol.145 , Issue.2 , pp. 212-220
    • Kouides, P.A.1    Byams, V.R.2    Philipp, C.S.3
  • 22
    • 77957220276 scopus 로고    scopus 로고
    • Tranexamic acid treatment for heavy menstrual bleeding: A randomized controlled trial
    • Lukes AS, Moore KA, Muse KN, et al. Tranexamic acid treatment for heavy menstrual bleeding: A randomized controlled trial. Obstet Gynecol 2010;116(4):865-75
    • (2010) Obstet Gynecol , vol.116 , Issue.4 , pp. 865-875
    • Lukes, A.S.1    Moore, K.A.2    Muse, K.N.3
  • 23
    • 0035703005 scopus 로고    scopus 로고
    • The effect of tranexamic acid on the quality of life of women with heavy menstrual bleeding
    • DOI 10.1016/S0301-2115(01)00414-6, PII S0301211501004146
    • Winkler UH. The effect of tranexamic acid on the quality of life of women with heavy menstrual bleeding. Eur J Obstet Gynecol Reprod Biol 2001;99(2):238-43 (Pubitemid 34098754)
    • (2001) European Journal of Obstetrics Gynecology and Reproductive Biology , vol.99 , Issue.2 , pp. 238-243
    • Winkler, U.H.1
  • 25
    • 34250710205 scopus 로고    scopus 로고
    • Ggynecological and obstetric management of women with inherited bleeding disorders
    • Demers C, Derzko C, Douglas J. Ggynecological and obstetric management of women with inherited bleeding disorders. Int J Gynecol Obstet 2006;95(1):75-87
    • (2006) Int J Gynecol Obstet , vol.95 , Issue.1 , pp. 75-87
    • Demers, C.1    Derzko, C.2    Douglas, J.3
  • 26
    • 27644442210 scopus 로고    scopus 로고
    • Management of excessive menstrual bleeding in women with hemostatic disorders
    • DOI 10.1016/j.fertnstert.2005.04.062, PII S0015028205027895
    • Kadir RA, Lukes AS, Kouides PA, et al. Management of excessive menstrual bleeding in women with hemostatic disorders. Fertil Steril 2005;84:1352-9 (Pubitemid 41571881)
    • (2005) Fertility and Sterility , vol.84 , Issue.5 , pp. 1352-1359
    • Kadir, R.A.1    Lukes, A.S.2    Kouides, P.A.3    Fernandez, H.4    Goudemand, J.5
  • 27
    • 0014927935 scopus 로고
    • Human placental transfer Aof an antifibrinolytic agent (AMCA)
    • Kullander S, Nilsson IM. Human placental transfer Aof an antifibrinolytic agent (AMCA). Acta Obstet Gynecol Scand 1970;49(3):241-2
    • (1970) Acta Obstet Gynecol Scand , vol.49 , Issue.3 , pp. 241-242
    • Kullander, S.1    Nilsson, I.M.2
  • 29
    • 0036342825 scopus 로고    scopus 로고
    • Pulmonary embolism associated with tranexamic acid in severe acqired haemophelia
    • Taparia M, Cordingley FT, Leahy MF. Pulmonary embolism associated with tranexamic acid in severe acqired haemophelia. Eur J Hematol 2002;68:307-9
    • (2002) Eur J Hematol , vol.68 , pp. 307-309
    • Taparia, M.1    Cordingley, F.T.2    Leahy, M.F.3
  • 31
    • 0033005358 scopus 로고    scopus 로고
    • Tranexamic acid: A review of its use in surgery and other indications
    • DOI 10.2165/00003495-199957060-00017
    • Dunn CJ, Goa KL. TA: A review of its use in surgery and other indications. Drugs 1999;57(6):1005-32 (Pubitemid 29313210)
    • (1999) Drugs , vol.57 , Issue.6 , pp. 1005-1032
    • Dunn, C.J.1    Goa, K.L.2
  • 33
    • 0030834247 scopus 로고    scopus 로고
    • Influence of early fibrinolysis inhibition on thrombus formation following microvascular trauma
    • DOI 10.1002/(SICI)1098-2752(1996)17:5<278::AID-MICR8>3.0.CO;2-F
    • Zhang B, Wieslander JB. Influence of early fibrinolysis inhibition on thrombus formation following microvascular trauma. Microsurgery 1996;17:278-85 (Pubitemid 27284254)
    • (1997) Microsurgery , vol.17 , Issue.5 , pp. 278-285
    • Zhang, B.1    Wieslander, J.B.2
  • 34
    • 0027317815 scopus 로고
    • Treatment with tranexamic acid during pregnancy, and the risk of thrombo-embolic complications
    • Lindoff C, Rybo G, Astedt B. Treatment with tranexamic acid during pregnancy, and risk of thrombo-embolic complications. Thromb Haemost 1993;70:238-40 (Pubitemid 23222474)
    • (1993) Thrombosis and Haemostasis , vol.70 , Issue.2 , pp. 238-240
    • Lindoff, C.1    Rybo, G.2    Astedt, B.3
  • 35
    • 57349119262 scopus 로고    scopus 로고
    • The risk of venous thromboembolism associated with the use of tranexamic acid and other drugs used to treat menorrhagia: A case-control study using the General Practice Research Database
    • Sundstrom A, Seaman H, Kieler H, Alfredsson L. The risk of venous thromboembolism associated with the use of tranexamic acid and other drugs used to treat menorrhagia: A case-control study using the General Practice Research Database. Br J Obstet Gynaecol 2009;116:91-7
    • (2009) Br J Obstet Gynaecol , vol.116 , pp. 91-97
    • Sundstrom, A.1    Seaman, H.2    Kieler, H.3    Alfredsson, L.4
  • 36
    • 0004770744 scopus 로고
    • Tranexamic acid therapy: Effective treatment in heavy menstrual bleeding: Clinical update on safety
    • Rybo G. Tranexamic acid therapy: Effective treatment in heavy menstrual bleeding: Clinical update on safety. Ther Adv 1991;4:1-8
    • (1991) Ther Adv , vol.4 , pp. 1-8
    • Rybo, G.1
  • 37
    • 0035703005 scopus 로고    scopus 로고
    • The effect of tranexamic acid on the quality of life of women with heavy menstrual bleeding
    • DOI 10.1016/S0301-2115(01)00414-6, PII S0301211501004146
    • Winkler UH. The effect of tranexamic acid on the quality of life of women with heavy menstrual bleeding. Eur J Obstet Gynecol Reprod Biol 2001;99(2):238-43 (Pubitemid 34098754)
    • (2001) European Journal of Obstetrics Gynecology and Reproductive Biology , vol.99 , Issue.2 , pp. 238-243
    • Winkler, U.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.