Cardiovascular alterations heralded by intrathecal baclofen bolus

NeuroRehabilitation

Volumn 28, Issue 4, 2011, Pages 389-393

  Rifici, Carmela ^a   D'Aleo, Giangaetano ^a   D'Aleo, Piercataldo ^a   Bramanti, Placido ^a   Saltuari, Leopold ^b,c   Kofler, Markus ^b  

^a IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^b Hospital Hochzirl   (Austria)

^c South Tyrol   (Italy)

Author keywords

cardiovascular alterations; Intrathecal baclofen

Indexed keywords

BACLOFEN; DIAZEPAM;

ADULT; ARTICLE; BRADYCARDIA; CARDIOVASCULAR SYSTEM EXAMINATION; CASE REPORT; CONTINUOUS INFUSION; DISEASE SEVERITY; ELECTROENCEPHALOGRAM; EVOKED AUDITORY RESPONSE; HEART ARREST; HEART RIGHT BUNDLE BRANCH BLOCK; HUMAN; HYPOTENSION; MALE; MUSCLE TONE; NUCLEAR MAGNETIC RESONANCE; SPASTICITY; SPINAL CORD INJURY; TRAUMATIC BRAIN INJURY;

ADULT; BACLOFEN; BRADYCARDIA; ELECTROCARDIOGRAPHY; HEART RATE; HUMANS; INJECTIONS, SPINAL; MALE; MIDDLE AGED; MUSCLE RELAXANTS, CENTRAL; MUSCLE SPASTICITY;

EID: 80051497465     PISSN: 10538135     EISSN: 18786448     Source Type: Journal    
DOI: 10.3233/NRE-2011-0668     Document Type: Article

References (36)

1. R. Becker, L. Benes, U. Sure, D. Hellwig and H. Bertalanffy, Intrathecal baclofen alleviates autonomic dysfunction in severe brain injury, Journal Clinical Neuroscience 7 (2000), 316-319. (Pubitemid 30612956)
2. R.W. Bohannon and M.B. Smith, Interrater reliability of a modified Ashworth Scale of muscle spasticity, Physical Therapy 67 (1987), 206-207. (Pubitemid 17026064)
3. N.G. Bowery and G.D. Pratt, GABA-B receptors as targets for drug action, Arzneimittelforschung 42 (1992), 215-223.
4. P. Bramanti, G. D'Aleo, C. Rifici, A. Alagna, A. Cannata, E. Sessa, P. Di Bella and G. Marra, Quality of life of patients with telemetric pumps for intrathecal baclofen infusion: Data and limitations of assessment scales, Functional Neurology 19 (2004), 227-231. (Pubitemid 40468286)
5. G. Bravo, G. Guìzar-Sahagùn, A. Ibarra, D. Centuriòn and C.M. Villaròn, Cardiovascular alterations after spinal cord injury: An overview, CurrentMedicinal Chemistry - Cardiovascular and Hematological Agents 2 (2004), 133-148. (Pubitemid 38854975)
6. J.C. Callera, L.G. Bonagamba, A. Nosjean, R. Laguzzi and B.H. Machado, Activation of GABA receptors in the NTS of awake rats reduces the gain of baroreflex bradycardia, Autonomic Neuroscience 84 (2000), 58-67.
7. Y.W. Cheng, M.C. Ku, C.M. Ho, C.Y. Chai and C.K. Su, GABAB-receptor- mediated suppression of sympathetic outflow from the spinal cord of neonatal rats, Journal of Applied Physiology 99 (2005), 1658-1567.
8. A. Crambes, L. Monassier, D. Chapleau, J.C. Roegel, J. Feldman and P. Bousquet, GABAergic and glutaminergic modulation of centrally arrhythmias in rats, Hypertension 27 (1996), 148-154. (Pubitemid 26017694)
9. G. D'Aleo, C. Rifici, M. Kofler, L. Saltuari and P. Bramanti, Favorable response to intrathecal, but not oral, baclofen of priapism in a patient with spinal cord injury, Spine 34 (2009), E127-E129.
10. G. D'Aleo, M. Kofler, C. Rifici, M. de Leonni Stanonik, L. Saltuari and P. Bramanti, Quality of life in caregivers of patients with supraspinal spasticity receiving intrathecal baclofen, Brain Injury 24 (2010), 320-321.
11. J.A. Hey, G. Mingo, D.C. Bolser, W. Kreutner, D. Krobatsch and R.W. Chapman, Respiratory effects of baclofen and 3- aminopropylphosphinic acid in guinea-pigs, British Journal of Pharmacology 114 (1995), 735-738.
12. A. Hilson, The physiology of spasticity, PostgraduateMedical Journal 48 (1972), 25-27.
13. Y.G. Hong and J.L. Henry, Cardiovascular responses to intrathecal administration of L- and D-baclofen in the rat, European Journal of Pharmacology 192 (1991), 55-62.
14. B.S. Kim, H.C.Koh, J.S. Kang, H. Lee, I.C. Shin, S.A.Omand J.H. Kang, Mediation of the cardiovascular response to spinal [gamma]-aminobutyric acidB receptor stimulation by adenosine A1 receptors in anesthetized rats, Neuroscience Letters 296 (2000), 153-157.
15. M.Kofler, H.Matzak and L. Saltuari, The impact of intrathecal baclofen on gastrointestinal function, Brain Injury 16 (2002), 825-836.
16. M. Kofler, K. Poustka and L. Saltuari, Intrathecal baclofen for autonomic instability due to spinal cord injury, Autonomic Neuroscience 146 (2009), 106-110.
17. C.R. Lazy, R.J. Contrada, M.L. Robbins, A.K. Tannenbaum, A.E. Moreyra, S. Chelton and J.B. Kostis, Coronary vasoconstriction induced bymental stress (simulated public speaking), American Journal of Cardiology 75 (1995), 503-505.
18. T.-H. Lee, S.-S. Chen, S.-L. Su and S.-S. Yang, Baclofen intoxication: Report of four cases and review of the literature, Clinical Neuropharmacology 15 (1992), 56-62.
19. N.Y. Leung, I.M.Whyte and G.K. Ibister, Baclofen overdose: Defining the spectrum of toxicity, Emergency Medicine Australasia 18 (2006), 77-82.
20. D.P. Li and H.L. Pan, Role of gamma-aminobutyric acid (GABA)-A and GABA-B receptors in paraventricular nucleus in control of sympathetic vasomotor tone in hypertension, Journal of Pharmacology and Experimental Therapeutics 320 (2007), 615-626.
21. M.A. Lyew, C. Mondy, S. Eagle and S.E. Chernic, Hemodynamic instability and delayed emergence from general anaesthesia associated with inadvertent intrathecal baclofen overdose, Anesthesiology 9 (2003), 265-268. (Pubitemid 36043436)
22. R.J. Marino, T. Barros, F. Biering-Sorensen, S.P. Burns, W.H. Donovan, D.E. Graves, M. Haak, L.M. Hudson and M.M. Priebe, ASIA Neurological Standards Committee 2002. International standards for neurological classification of spinal cord injury, Journal of Spinal Cord Medicine 26 (2003), S50-S56.
23. L. Monassier, C.M. Brandt and P. Bousquet, Effects of centrally-acting glutamatergic modulators on cardiovascular responses to stress in humans, The American Journal of Cardiology 37(Suppl 1) (2001), 77-84.
24. H. Müller, J. Zierski, D. Dralle, D. Krauss and E. Mutschler, Pharmacokinetics of intrathecal baclofen, in: Local-spinal Therapy of Spasticity, H. Müller, J. Zierski and R.D. Penn, eds, Berlin, Heidelberg, New York, London, Paris, Tokyo, Springer, 1988, pp. 223-226.
25. S. Nugent, M.D. Katz and T.E. Little, Baclofen overdose with cardiac conduction abnormalities: Case report and review of the literature, Journal of Toxicology - Clinical Toxicology 24 (1986), 321-328. (Pubitemid 17174807)
26. A.F. Pizon and F. Lovecchio, Reversible cardiomyopathy complicating intrathecal baclofen withdrawal: A case report, Journal of Medical Toxicology 3 (2007), 187-189.
27. C. Rifici, M. Kofler, M. Kronenberg, A. Kofler, P. Bramanti and L. Saltuari, Intrathecal baclofen application in patients with supraspinal spasticity secondary to severe traumatic brain injury, Functional Neurology 9 (1994), 29-34. (Pubitemid 24142313)
28. D.A. Ruggiero, M.D. Underwood, J.J. Mann, M. Anwar, J.J. Mann and D.J. Reis, The human nucleus of the solitary tract: Visceral pathways revealed with an "in vitro" postmortem tracing method, Journal of the Autonomic Nervous System 79 (2000), 181-190. (Pubitemid 30107866)
29. L. Saltuari, M. Kronenberg, M.J. Marosi, M. Kofler, L. Russegger, C. Rifici, P. Bramanti and F. Gerstenbrand, Indication, efficiency and complications of intrathecal pump supported baclofen treatment in spinal spasticity, Acta Neurologica 14 (1992), 187-194.
30. L. Saltuari, M. Kronenberg, M.J. Marosi, M. Kofler, L. Russegger, C. Rifici, P. Bramanti and F. Gerstenbrand, Longterm intrathecal baclofen treatment in supraspinal spasticity, Acta Neurologica 14 (1992), 195-207.
31. L. Saltuari,M.J.Marosi,M.Kofler andG.Bauer, Status epilepticus complicating intrathecal baclofen overdose, Lancet 339 (1992), 373-374.
32. C.A. Smit and E.J. Slim, Heart conduction problems in a tetraplegic patient caused a single therapeutic dosage of baclofen, Spinal Cord 46 (2007), 1-2.
33. A.F. Sved and K. Tsukamoto, Tonic stimulation of GABAB receptors in the nucleus tractus solitarius modulates the baroreceptor reflex, Brain Research 592 (1992), 37-43.
34. T. Trippenbach and N. Lake, Excitatory cardiovascular and respiratory effects of baclofen in intact rats, Can J Physiol Pharmacol 72 (1994), 1200-1207.
35. X. Wang, Nicotinic receptors partly mediate brainstem autonomic dysfunction evoked by the inhaled anesthetic isoflurane, Anesth Analg 108 (2009), 134-141.
36. C.S. Yuan, D. Liu and A.S. Attele, GABAergic effects on nucleus tractus solitarius neurons receiving gastric vagal inputs, Journal of Pharmacolology and Experimental Therapeutics 286 (1998), 736-741. (Pubitemid 29003463)