Successful outcome of pregnancy in a patient with Cushing's disease under treatment with ketoconazole during the first trimester of gestation

Gynecological Endocrinology

Volumn 27, Issue 9, 2011, Pages 675-677

  Boronat, Mauro ^a   Marrero, Dunia ^a   López Plasencia, Yaiza ^a   Barber, Miguel ^b   Schamann, Yaiza ^b   Nóvoa, Francisco J ^a  

^a HOSPITAL UNIVERSITARIO INSULAR DE GRAN CANARIA   (Spain)

^b HOSPITAL UNIVERSITARIO MATERNO INFANTIL DE CANARIAS   (Spain)

Author keywords

Adrenal gland; pituitary gland; pregnancy

Indexed keywords

DEXAMETHASONE; GADOLINIUM; KETOCONAZOLE; LABETALOL; LOSARTAN; METHYLDOPA; METYRAPONE;

ABDOMINAL OBESITY; ADRENAL INSUFFICIENCY; ADULT; ARTICLE; ATROPHIC SKIN DISEASE; CASE REPORT; CUSHING DISEASE; DELIVERY; DRUG DOSE INCREASE; DRUG SAFETY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; FETUS RISK; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HIRSUTISM; HUMAN; HYDROCORTISONE URINE LEVEL; HYPOPHYSIS ADENOMA; LABOR INDUCTION; MATERNAL HYPERTENSION; NEWBORN DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL EXAMINATION; PREGNANCY DIABETES MELLITUS; PREGNANCY OUTCOME; PRIORITY JOURNAL; REMISSION; SECOND TRIMESTER PREGNANCY; THIRD TRIMESTER PREGNANCY; TRANSSPHENOIDAL SURGERY;

14-ALPHA DEMETHYLASE INHIBITORS; ACTH-SECRETING PITUITARY ADENOMA; ADULT; CUSHING SYNDROME; FEMALE; HUMANS; INFANT, NEWBORN; KETOCONAZOLE; MALE; PITUITARY ACTH HYPERSECRETION; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY OUTCOME; PREGNANCY TRIMESTER, FIRST;

EID: 80051496453     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.3109/09513590.2010.521268     Document Type: Article

References (15)

1. Lindsay JR, Jonklaas J, Oldfield EH, Nieman LK. Cushing's syndrome during pregnancy: personal experience and review of the literature. J Clin Endocrinol Metab 2005;90:3077-3083. (Pubitemid 40686367)
2. Biller BMK, Grossman AB, Stewart PM,Melmed S, Bertagna X, Bertherat J, Buchfelder M, Colao A, Hermus AR, Hofland LJ, et al. Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement. J Clin Endocrinol Metab 2008;93:2454-2462. (Pubitemid 352008503)
3. Pricolo VE, Monchik JM, Prinz RA, DeJong S, Chadwick DA, Lamberton RP. Management of Cushing's syndrome secondary to adrenal adenoma during pregnancy. Surgery 1990;108: 1072-1077.
4. Moudgal VV, Sobel JD. Antifungal drugs in pregnancy: a review. Expert Opin Drug Saf 2003;2:475-483.
5. Sonino N, Boscaro M, Paoletta A, Mantero F, Ziliotto D. Ketoconazole treatment in Cushing's syndrome: experience in 34 patients. Clin Endocrinol (Oxf) 1991;35:347-352.
6. Kazy Z, PuhóE, Czeizel AE. Population-based case-control study of oral ketoconazole treatment for birth outcomes. Congenit Anom (Kyoto) 2005;45:5-8. (Pubitemid 41657747)
7. Amado JA, Pesquera C, González EM, Otero M, Freijanes J, Álvarez A. Successful treatment with ketoconazole of Cushing's syndrome in pregnancy. Postgrad Med J 1990;66: 221-223. (Pubitemid 20083082)
8. Prebtani APH, Donat D, Ezzat S. Worrisome striae. Lancet 2000;355:1692.
9. Bewaerts J, Vevhelst J, Mahlev C, Abs R. Cushing's syndrome in pregnancy treated by ketoconazole: case report and review of the literature. Gynecol Endocrinol 1999;13:175-182. (Pubitemid 29313216)
10. Casson IF, Davis JC, Jeffreys RV, Silas JH, Williams J, Belchetz PE. Successful management of Cushing's disease during pregnancy by transsphenoidal adenectomy. Clin Endocrinol (Oxf) 1987;27:423-428. (Pubitemid 17148597)
11. Coyne TJ, Atkinson RL, Prins JB. Adrenocorticotropic hormone-secreting pituitary tumor associated with pregnancy: case report. Neurosurgery 1992;31:953-955.
12. Ross RJM, Chew SL, Perry L, Erskine K, Medbak S, Afshar F. Diagnosis and selective cure of Cushing's disease during pregnancy by transsphenoidal surgery. Eur J Endocrinol 1995; 132:722-7226.
13. Mellor A, Harvey RD. Pobereskin LH, Sneyd JR. Cushing's disease treated by trans-sphenoidal selective adenomectomy in mid-pregnancy. Br J Anaesth 1998;80:850-852. (Pubitemid 28282567)
14. Verdugo C, Alegría J, Grant C, Briano E, González MI, Meza H, Amthauer N, Paiva O, Vigueras R, Madariaga J. Cushing's disease treatment with transsphenoidal surgery during pregnancy. Report of one case. Rev Med Chil 2004;132:75-80.
15. Estrada J, García-Uría J, Lamas C, Alfaro J, Lucas T, Díez S, Salto L, BarcelóB. The complete normalization of the adrenocortical function as the criterion of cure after transsphenoidal surgery for Cushing's disease. J Clin Endocrinol Metab 2001;86:5695-5699. (Pubitemid 33152610)