BLM deficiency is not associated with sensitivity to hydroxyurea-induced replication stress

Journal of Nucleic Acids

Volumn 2010, Issue , 2010, Pages

  Lahkim Bennani Belhaj, Kenza ^a,b   Buhagiar Labarchède, Géraldine ^a,b   Jmari, Nada ^a,b   Onclercq Delic, Rosine ^a,b   Amor Guéret, Mounira ^a,b  

^a INSTITUT CURIE   (France)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOM SYNDROME HELICASE; CHECKPOINT KINASE 2; HISTONE H2AX; HYDROXYUREA; RAD51 PROTEIN; SMALL INTERFERING RNA;

ARTICLE; BLOOM SYNDROME; CANCER RISK; CELL SURVIVAL; CHROMOSOMAL INSTABILITY; CLONOGENESIS; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; DNA STRAND BREAKAGE; DOWN REGULATION; ENZYME DEFICIENCY; FIBROBLAST; GENOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SISTER CHROMATID EXCHANGE; WESTERN BLOTTING;

EID: 80051494507     PISSN: 20900201     EISSN: 2090021X     Source Type: Journal    
DOI: 10.4061/2010/319754     Document Type: Article

References (42)

1. Ellis N. A., Groden J., Ye T.-Z., Straughen J., Lennon D. J., Ciocci S., Proytcheva M., German J., The Bloom's syndrome gene product is homologous to RecQ helicases. Cell 1995 83 4 655 666 2-s2.0-0028785586
2. Otsuki M., Seki M., Inoue E., Yoshimura A., Kato G., Yamanouchi S., Kawabe Y.-I., Tada S., Shinohara A., Komura J.-I., Ono T., Takeda S., Ishii Y., Enomoto T., Functional interactions between BLM and XRCC3 in the cell. Journal of Cell Biology 2007 179 1 53 63 2-s2.0-35348941829 10.1083/jcb.200702183 (Pubitemid 47606683)
3. Sonoda E., Sasaki M. S., Morrison C., Yamaguchi-Iwai Y., Takata M., Takeda S., Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells. Molecular and Cellular Biology 1999 19 7 5166 5169 2-s2.0-0032999346 (Pubitemid 29289554)
4. Bennani-Belhaj K. L., Rouzeau S., Buhagiar-Labarchède G., Chabosseau P., Onclercq-Delic R., Bayart E., Cordelières F., Couturier J., Amor-Guéret M., The Bloom syndrome protein limits the lethality associated with RAD51 deficiency. Molecular Cancer Research 2010 8 3 385 394 2-s2.0-0033856663 10.1158/1541-7786.MCR-09-0534
5. Hand R., German J., A retarded rate of DNA chain growth in Bloom's syndrome. Proceedings of the National Academy of Sciences of the United States of America 1975 72 2 758 762 2-s2.0-3142546346
6. Giannelli F., Benson P. F., Pawsey S. A., Polani P. E., Ultraviolet light sensitivity and delayed DNA chain maturation in Bloom's syndrome fibroblasts. Nature 1977 265 5593 466 469 2-s2.0-0017357401 (Pubitemid 8023614)
7. Lonn U., Lonn S., Nylen U., Winblad G., German J., An abnormal profile of DNA replication intermediates in Bloom's syndrome. Cancer Research 1990 50 11 3141 3145 2-s2.0-0025302748 (Pubitemid 20190107)
8. Davies S. L., North P. S., Hickson I. D., Role for BLM in replication-fork restart and suppression of origin firing after replicative stress. Nature Structural and Molecular Biology 2007 14 7 677 679 2-s2.0-34447115757 10.1038/nsmb1267 (Pubitemid 47037072)
9. Rao V. A., Conti C., Guirouilh-Barbat J., Nakamura A., Miao Z.-H., Davies S. L., Saccá B., Hickson I. D., Bensimon A., Pommier Y., Endogenous γ -H2AX-ATM-Chk2 checkpoint activation in Bloom's syndrome helicase-deficient cells is related to DNA replication arrested forks. Molecular Cancer Research 2007 5 7 713 724 2-s2.0-34547132330 10.1158/1541-7786.MCR-07- 0028 (Pubitemid 47105490)
10. German J., Bloom's syndrome. Dermatologic Clinics 1995 13 1 7 18 2-s2.0-0028831333
11. Wu L., Davies S. L., Levitt N. C., Hickson I. D., Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51. The Journal of Biological Chemistry 2001 276 22 19375 19381 2-s2.0-0035377356 10.1074/jbc.M009471200
12. Tripathi V., Nagarjuna T., Sengupta S., BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination. Journal of Cell Biology 2007 178 1 9 14 2-s2.0-34347388428 10.1083/jcb.200610051 (Pubitemid 47026397)
13. Sengupta S., Robles A. I., Linke S. P., Sinogeeva N. I., Zhang R., Pedeux R., Ward I. M., Celeste A., Nussenzweig A., Chen J., Halazonetis T. D., Harris C. C., Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest. Journal of Cell Biology 2004 166 6 801 813 2-s2.0-4544235194 10.1083/jcb.200405128 (Pubitemid 39249832)
14. Bischof O., Kim S.-H., Irving J., Beresten S., Ellis N. A., Campisi J., Regulation and localization of the Bloom syndrome protein in response to DNA damage. Journal of Cell Biology 2001 153 2 367 380 2-s2.0-0035897415 10.1083/jcb.153.2.367 (Pubitemid 34280221)
15. Sengupta S., Linke S. P., Pedeux R., Yang Q., Farnsworth J., Garfield S. H., Valerie K., Shay J. W., Ellis N. A., Wasylyk B., Harris C. C., BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination. EMBO Journal 2003 22 5 1210 1222 2-s2.0-0037416149 10.1093/emboj/cdg114 (Pubitemid 36313604)
16. Tripathi V., Kaur S., Sengupta S., Phosphorylation-dependent interactions of BLM and 53BP1 are required for their anti-recombinogenic roles during homologous recombination. Carcinogenesis 2008 29 1 52 61 2-s2.0-38849137795 10.1093/carcin/bgm238 (Pubitemid 351201741)
17. Ouyang K. J., Woo L. L., Zhu J., Huo D., Matunis M. J., Ellis N. A., SUMO modification regulates BLM and RAD51 interaction at damaged replication forks. PLoS Biology 2009 7 12 e1000252 2-s2.0-0035898405 10.1371/journal.pbio.1000252
18. Karow J. K., Constantinou A., Li J.-L., West S. C., Hickson I. D., The Bloom's syndrome gene product promotes branch migration of Holliday junctions. Proceedings of the National Academy of Sciences of the United States of America 2000 97 12 6504 6508 2-s2.0-0034612333 10.1073/pnas.100448097 (Pubitemid 30412743)
19. van Brabant A. J., Ye T., Sanz M., German J. L. III, Ellis N. A., Holloman W. K., Binding and melting of D-loops by the Bloom syndrome helicase. Biochemistry 2000 39 47 14617 14625 2-s2.0-0034727684 10.1021/bi0018640
20. Bachrati C. Z., Borts R. H., Hickson I. D., Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase. Nucleic Acids Research 2006 34 8 2269 2279 2-s2.0-33646843592 10.1093/nar/gkl258 (Pubitemid 43985665)
21. Raynard S., Bussen W., Sung P., A double holliday junction dissolvasome comprising BLM, topoisomerase III α and BLAP75. The Journal of Biological Chemistry 2006 281 20 13861 13864 2-s2.0-33744927719 10.1074/jbc.C600051200 (Pubitemid 43848308)
22. Wu L., Bachrati C. Z., Ou J., Xu C., Yin J., Chang M., Wang W., Li L., Brown G. W., Hickson I. D., BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates. Proceedings of the National Academy of Sciences of the United States of America 2006 103 11 4068 4073 2-s2.0-33645242115 10.1073/pnas.0508295103
23. Machwe A., Xiao L., Groden J., Orren D. K., The Werner and Bloom syndrome proteins catalyze regression of a model replication fork. Biochemistry 2006 45 47 13939 13946 2-s2.0-33751581731 10.1021/bi0615487 (Pubitemid 44846182)
24. Ralf C., Hickson I. D., Wu L., The Bloom's syndrome helicase can promote the regression of a model replication fork. The Journal of Biological Chemistry 2006 281 32 22839 22846 2-s2.0-33747352774 10.1074/jbc.M604268200
25. Bugreev D. V., Yu X., Egelman E. H., Mazin A. V., Novel pro- and anti-recombination activities of the Bloom's syndrome helicase. Genes and Development 2007 21 23 3085 3094 2-s2.0-36849029846 10.1101/gad.1609007 (Pubitemid 350223526)
26. Amor-Guéret M., Bloom syndrome, genomic instability and cancer: the SOS-like hypothesis. Cancer Letters 2006 236 1 1 12 2-s2.0-33745398364 10.1016/j.canlet.2005.04.023 (Pubitemid 44382536)
27. Wu L., Role of the BLM helicase in replication fork management. DNA Repair 2007 6 7 936 944 2-s2.0-34249946979 10.1016/j.dnarep.2007.02.007 (Pubitemid 46880474)
28. Alvino G. M., Collingwood D., Murphy J. M., Delrow J., Brewer B. J., Raghuraman M. K., Replication in hydroxyurea: it's a matter of time. Molecular and Cellular Biology 2007 27 18 6396 6406 2-s2.0-34548789595 10.1128/MCB.00719-07 (Pubitemid 47435746)
29. Imamura O., Fujita K., Shimamoto A., Tanabe H., Takeda S., Furuichi Y., Matsumoto T., Bloom helicase is involved in DNA surveillance in early s phase in vertebrate cells. Oncogene 2001 20 10 1143 1151 2-s2.0-0035826264 10.1038/sj.onc.1204195 (Pubitemid 32226240)
30. Ababou M., Dumaire V., Lécluse Y., Amor-Guéret M., Cleavage of BLM and sensitivity of Bloom's syndrome cells to hydroxurea and UV-C radiation. Cell Cycle 2002 1 4 262 266 2-s2.0-0036633007
31. Davies S. L., North P. S., Dart A., Lakin N. D., Hickson I. D., Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest. Molecular and Cellular Biology 2004 24 3 1279 1291 2-s2.0-1642458364 10.1128/MCB.24.3.1279-1291.2004 (Pubitemid 38112189)
32. Dutertre S., Ababou M., Onclercq R., Delic J., Chatton B., Jaulin C., Amor-Guéret M., Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase. Oncogene 2000 19 23 2731 2738 2-s2.0-0034713244 (Pubitemid 30339222)
33. Eladad S., Ye T.-Z., Hu P., Leversha M., Beresten S., Matunis M. J., Ellis N. A., Intra-nuclear trafficking of the BLM helicase to DNA damage-induced foci is regulated by SUMO modification. Human Molecular Genetics 2005 14 10 1351 1365 2-s2.0-19744378341 10.1093/hmg/ddi145 (Pubitemid 40744493)
34. Ababou M., Dumaire V., Lécluse Y., Amor-Guéret M., Bloom's syndrome protein response to ultraviolet-C radiation and hydroxyurea-mediated DNA synthesis inhibition. Oncogene 2002 21 13 2079 2088 2-s2.0-0037150227 10.1038/sj/onc/1205246 (Pubitemid 34270896)
35. Saintigny Y., Delacôte F., Varès G., Petitot F., Lambert S., Averbeck D., Lopez B. S., Characterization of homologous recombination induced by replication inhibition in mammalian cells. EMBO Journal 2001 20 14 3861 3870 2-s2.0-0035898405 10.1093/emboj/20.14.3861 (Pubitemid 32694383)
36. Zhao H., Piwnica-Worms H., ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Molecular and Cellular Biology 2001 21 13 4129 4139 2-s2.0-0034967556 10.1128/MCB.21.13.4129-4139.2001 (Pubitemid 32565295)
37. Speit G., Schütz P., The effect of inhibited replication on DNA migration in the comet assay in relation to cytotoxicity and clastogenicity. Mutation Research 2008 655 1-2 22 27 2-s2.0-58149311023
38. Matsuoka A., Lundin C., Johansson F., Sahlin M., Fukuhara K., Sjöberg B.-M., Jenssen D., Önfelt A., Correlation of sister chromatid exchange formation through homologous recombination with ribonucleotide reductase inhibition. Mutation Research 2004 547 1-2 101 107 2-s2.0-1542375450 10.1016/j.mrfmmm.2003.12.002 (Pubitemid 38315077)
39. Rao V. A., Fan A. M., Meng L., Doe C. F., North P. S., Hickson I. D., Pommier Y., pommier@nih.gov Phosphorylation of BLM, dissociation from topoisomerase III α and colocalization with γ -H2AX after topoisomerase I-induced replication damage. Molecular and Cellular Biology 2005 25 20 8925 8937 2-s2.0-0033598931 10.1128/MCB.25.20.8925-8937.2005 (Pubitemid 41429083)
40. Hsiang Y.-H., Lihou M. G., Liu L. F., Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Research 1989 49 18 5077 5082 2-s2.0-0024420685 (Pubitemid 19239347)
41. Bartkova J., Hoejší Z., Koed K., Krämer A., Tort F., Zleger K., Guldberg P., Sehested M., Nesland J. M., Lukas C., Orntoft T., Lukas J., Bartek J., DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 2005 434 7035 864 870 2-s2.0-17244367849 10.1038/nature03482 (Pubitemid 40558993)
42. Gorgoulis V. G., Vassiliou L.-V. F., Karakaidos P., Zacharatos P., Kotsinas A., Liloglou T., Venere M., DiTullio R. A. Jr., Kastrinakis N. G., Levy B., Kletsas D., Yoneta A., Herlyn M., Kittas C., Halazonetis T. D., Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 2005 434 7035 907 913 2-s2.0-17244366865 10.1038/nature03485 (Pubitemid 40559004)