Wood bark smoke induces lung and pleural plasminogen activator inhibitor 1 and stabilizes its mRNA in porcine lung cells

Shock

Volumn 36, Issue 2, 2011, Pages 128-137

  Midde, Krishna K ^a   Batchinsky, Andriy I ^b   Cancio, Leopoldo C ^b   Shetty, Sreerama ^a   Komissarov, Andrey A ^a   Florova, Galina ^a   Walker, Kerfoot P ^b   Koenig, Kathy ^a   Chroneos, Zissis C ^c   Allen, Tim ^a   Chung, Kevin ^b   Dubick, Michael ^b   Idell, Steven ^a  

^a UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

^b US Army Institute of Surgical Research   (United States)

^c Department of Biochemistry ^*  (United States)

Author keywords

Acute lung injury; fibrin; fibrinolysis; serpin; smoke inhalation

Indexed keywords

BINDING PROTEIN; FIBRIN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN;

ACUTE LUNG INJURY; AIRWAY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; EXTRAVASCULAR SPACE; FEMALE; GEL MOBILITY SHIFT ASSAY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LUNG; LUNG ALVEOLUS; LUNG ALVEOLUS CELL; LUNG FIBROBLAST; LUNG LAVAGE; MESOTHELIUM CELL; NONHUMAN; PLEURA; PLEURA DISEASE; PLEURA MESOTHELIAL CELL; POLYMERASE CHAIN REACTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; SMOKE; SMOKE INDUCED ACUTE LUNG INJURY; SWINE; TRANSCRIPTION REGULATION; WESTERN BLOTTING; WOOD BARK SMOKE;

ACUTE LUNG INJURY; ANIMALS; CELLS, CULTURED; FEMALE; FIBRIN; LUNG; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLEURA; RANDOM ALLOCATION; SMOKE; SWINE;

EID: 80051492743     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e31821d60a4     Document Type: Article

References (24)

1. Enkhbaatar P, Traber DL: Pathophysiology of acute lung injury in combined burn and smoke inhalation injury. Clin Sci (Lond) 107(2):137-143, 2004. (Pubitemid 39070929)
2. Demling RH: Smoke inhalation lung injury: an update. Eplasty 8:e27, 2008.
3. Enkhbaatar P, Murakami K, Cox R, Westphal M, Morita N, Brantley K, Burke A, Hawkins H, Schmalstieg F, Traber L, et al.: Aerosolized tissue plasminogen inhibitor improves pulmonary function in sheep with burn and smoke inhalation. Shock 22(1):70-75, 2004. (Pubitemid 40228213)
4. Enkhbaatar P, Cox RA, Traber LD, Westphal M, Aimalohi E, Morita N, Prough DS, Herndon DN, Traber DL: Aerosolized anticoagulants ameliorate acute lung injury in sheep after exposure to burn and smoke inhalation. Crit Care Med 35(12):2805-2810, 2007. (Pubitemid 350175779)
5. Murakami K, McGuire R, Cox RA, Jodoin JM, Bjertnaes LJ, Katahira J, Traber LD, Schmalstieg FC, Hawkins HK, Herndon DN, et al.: Heparin nebulization attenuates acute lung injury in sepsis following smoke inhalation in sheep. Shock 18(3):236-241, 2002.
6. Idell S: Coagulation, fibrinolysis, and fibrin deposition in acute lung injury. Crit Care Med 31(suppl 4):S213-S220, 2003. (Pubitemid 36458170)
7. Idell S, James KK, Levin EG, Schwartz BS, Manchanda N, Maunder RJ, Martin TR, McLarty J, Fair DS: Local abnormalities in coagulation and fibrinolytic pathways predispose to alveolar fibrin deposition in the adult respiratory distress syndrome. J Clin Invest 84(2):695-705, 1989. (Pubitemid 19197006)
8. Shetty S, Padijnayayveetil J, Tucker T, Stankowska D, Idell S: The fibrinolytic system and the regulation of lung epithelial cell proteolysis, signaling, and cellular viability. Am J Physiol Lung Cell Mol Physiol 295(6):L967-L975, 2008.
9. Sapru A, Curley MA, Brady S, Matthay MA, Flori H: Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. Intensive Care Med 36(1):157-163, 2010.
10. Tsangaris I, Tsantes A, Bonovas S, Lignos M, Kopterides P, Gialeraki A, Rapti E, Orfanos S, Dimopoulou I, Travlou A, et al.: The impact of the PAI-1 4G/5G polymorphism on the outcome of patients with ALI/ARDS. Thromb Res 123(6):832-836, 2009.
11. Prabhakaran P, Ware LB, White KE, Cross MT, Matthay MA, Olman MA: Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury. Am J Physiol Lung Cell Mol Physiol 285(1):L20-L28, 2003. (Pubitemid 36736464)
12. Aoki K, Aikawa N, Sekine K, Yamazaki M, Mimura T, Urano T, Takada A: Elevation of plasma free PAI-1 levels as an integrated endothelial response to severe burns. Burns 27(6):569-575, 2001. (Pubitemid 32755746)
13. Dimova EY, Kietzmann T: Metabolic, hormonal and environmental regulation of plasminogen activatorinhibitor-1 (PAI-1) expression: lessons from the liver. Thromb Haemost 100(6):992-1006, 2008.
14. Park MS, Cancio LC, Batchinsky AI, McCarthy MJ, Jordan BS, Brinkley WW, Dubick MA, Goodwin CW: Assessment of severity of ovine smoke inhalation injury by analysis of computed tomographic scans. J Trauma 55(3):417-427, 2003.
15. Murphy SA, Dinsdale D, Hoet P, Nemery B, Richards RJ: A comparative study of the isolation of type II epithelial cells from bat, hamster, pig and human lung tissue. Methods Cell Sci 21(1):31-38, 1999. (Pubitemid 29373960)
16. Shetty S, Idell S: A urokinase receptor MRNA binding protein from rabbit lung fibroblasts and mesothelial cells. Am J Physiol 274(6 pt 1):L871-L882, 1998.
17. Idell S, Allen T, Chen S, Koenig K, Mazar A, Azghani A: Intrapleural activation, processing, efficacy, and duration of protection of single-chain urokinase in evolving tetracycline-induced pleural injury in rabbits. Am J Physiol Lung Cell Mol Physiol 292(1):L25YL32, 2007. (Pubitemid 46103427)
18. Komissarov AA, Mazar AP, Koenig K, Kurdowska AK, Idell S: Regulation of intrapleural fibrinolysis by urokinase-alpha-macroglobulin complexes in tetracycline-induced pleural injury in rabbits. AM J Physiol Lung Cell Mol Physiol 297(4):L568YL577, 2009.
19. Shetty S, Shetty P, Idell S, Velusamy T, Bhandary YP, Shetty RS: Regulation of plasminogen activator inhibitor-1 expression by tumor suppressor protein P53. J Biol Chem 283(28):19570-19580, 2008.
20. Shetty S, Velusamy T, Shetty RS, Marudamuthu AS, Shetty SK, Florova G, Tucker T, Koenig K, Shetty P, Bhandary YP, et al.: Posttranscriptional regulation of plasminogen activator inhibitor-1 expression in human pleural mesothelial cells. Am J Respir Cell Mol Biol 43(3):358-367, 2009.
21. Wagers SS, Norton RJ, Rinaldi LM, Bates JH, Sobel BE, Irvin CG: Extravascular fibrin, plasminogen activator, plasminogen activator inhibitors, and airway hyperresponsiveness. J Clin Invest 114(1):104-111, 2004. (Pubitemid 39071649)
22. Allen GB, Cloutier ME, Larrabee YC, Tetenev K, Smiley ST, Bates JH: Neither fibrin nor plasminogen activator inhibitor-1 deficiency protects lung function in a mouse model of acute lung injury. Am J Physiol Lung Cell Mol Physiol 296(3):L277-L285, 2009.
23. Hardaway RM, Williams CH, Marvasti M, Farias M, Tseng A, Pinon I, Yanez D, Martinez M, Navar J: Prevention of adult respiratory distress syndrome with plasminogen activator in pigs. Crit Care Med 18(12):1413-1428, 1990.
24. Hardaway RM, Harke H, Williams CH: Fibrinolytic agents: a new approach to the treatment of adult respiratory distress syndrome. Adv Ther 11(2):43-51, 1994. (Pubitemid 24144785)