-
1
-
-
0035912939
-
Nitroglycerin and delayed preconditioning in humans: Yet another new mechanism for an old drug?
-
Heusch G. Nitroglycerin and delayed preconditioning in humans. Yet another new mechanism for an old drug?. Circulation. 2001 ; 103 (24). 2876-2878 (Pubitemid 32578120)
-
(2001)
Circulation
, vol.103
, Issue.24
, pp. 2876-2878
-
-
Heusch, G.1
-
2
-
-
0034772136
-
Signal transduction of ischemic preconditioning
-
DOI 10.1016/S0008-6363(01)00384-4, PII S0008636301003844
-
Schulz R, Cohen MV, Behrends M, Downey JM, Heusch G. Signal transduction of ischemic preconditioning. Cardiovasc Res. 2001 ; 52 (2). 181-198 (Pubitemid 33000395)
-
(2001)
Cardiovascular Research
, vol.52
, Issue.2
, pp. 181-198
-
-
Schulz, R.1
Cohen, M.V.2
Behrends, M.3
Downey, J.M.4
Heusch, G.5
-
3
-
-
41149145607
-
Pathophysiology of myocardial infarction. Protection by ischemic pre- and postconditioning
-
DOI 10.1007/s00059-008-3101-9
-
Skyschally A, Schulz R, Heusch G. Pathophysiology of myocardial infarction: protection by ischemic pre-and postconditioning. Herz. 2008 ; 33 (2). 88-100 (Pubitemid 351437850)
-
(2008)
Herz
, vol.33
, Issue.2
, pp. 88-100
-
-
Skyschally, A.1
Schulz, R.2
Heusch, G.3
-
4
-
-
57149142506
-
Cardioprotection: Nitric oxide, protein kinases, and mitochondria
-
Heusch G, Boengler K, Schulz R. Cardioprotection: nitric oxide, protein kinases, and mitochondria. Circulation. 2008 ; 118 (19). 1915-1919
-
(2008)
Circulation
, vol.118
, Issue.19
, pp. 1915-1919
-
-
Heusch, G.1
Boengler, K.2
Schulz, R.3
-
5
-
-
78649320661
-
Translating novel strategies for cardioprotection: The Hatter Workshop Recommendations
-
Hausenloy DJ, Baxter G, Bell R, et al. Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations. Basic Res Cardiol. 2010 ; 105 (6). 677-686
-
(2010)
Basic Res Cardiol
, vol.105
, Issue.6
, pp. 677-686
-
-
Hausenloy, D.J.1
Baxter, G.2
Bell, R.3
-
6
-
-
77954789419
-
Postconditioning and protection from reperfusion injury: Where do we stand?
-
Ovize M, Baxter GF, Di Lisa F, et al. Postconditioning and protection from reperfusion injury: where do we stand?. Cardiovasc Res. 2010 ; 87 (3). 406-423
-
(2010)
Cardiovasc Res
, vol.87
, Issue.3
, pp. 406-423
-
-
Ovize, M.1
Baxter, G.F.2
Di Lisa, F.3
-
7
-
-
42149115647
-
Heart rate in the pathophysiology of coronary blood flow and myocardial ischaemia: Benefit from selective bradycardic agents
-
Heusch G. Heart rate in the pathophysiology of coronary blood flow and myocardial ischaemia: benefit from selective bradycardic agents. Br J Pharmacol. 2008 ; 153 (8). 1589-1610
-
(2008)
Br J Pharmacol
, vol.153
, Issue.8
, pp. 1589-1610
-
-
Heusch, G.1
-
8
-
-
79251546445
-
Heart rate and heart failure
-
Heusch G. Heart rate and heart failure. Circ J. 2011 ; 75 (2). 229-236
-
(2011)
Circ J
, vol.75
, Issue.2
, pp. 229-236
-
-
Heusch, G.1
-
9
-
-
52449095304
-
Improvement of regional myocardial blood flow and function and reduction of infarct size with ivabradine-protection beyond heart rate reduction
-
Heusch G, Skyschally A, Gres P, van Caster P, Schilawa D, Schulz R. Improvement of regional myocardial blood flow and function and reduction of infarct size with ivabradine-protection beyond heart rate reduction. Eur Heart J. 2008 ; 29 (18). 2265-2275
-
(2008)
Eur Heart J
, vol.29
, Issue.18
, pp. 2265-2275
-
-
Heusch, G.1
Skyschally, A.2
Gres, P.3
Van Caster, P.4
Schilawa, D.5
Schulz, R.6
-
10
-
-
78649688372
-
Vascular pathophysiology in response to increased heart rate
-
Custodis F, Schirmer SH, Baumhakel M, Heusch G, Bohm M, Laufs U. Vascular pathophysiology in response to increased heart rate. J Am Coll Cardiol. 2010 ; 56 (24). 1973-1983
-
(2010)
J Am Coll Cardiol
, vol.56
, Issue.24
, pp. 1973-1983
-
-
Custodis, F.1
Schirmer, S.H.2
Baumhakel, M.3
Heusch, G.4
Bohm, M.5
Laufs, U.6
-
11
-
-
0028947940
-
Bradycardic agent UL-FS 49 attenuates ischemic regional dysfunction and reduces infarct size in swine: Comparison with the beta-blocker atenolol
-
Schulz R, Rose J, Skyschally A, Heusch G. Bradycardic agent UL-FS 49 attenuates ischemic regional dysfunction and reduces infarct size in swine: comparison with the beta-blocker atenolol. J Cardiovasc Pharmacol. 1995 ; 25 (2). 216-228
-
(1995)
J Cardiovasc Pharmacol
, vol.25
, Issue.2
, pp. 216-228
-
-
Schulz, R.1
Rose, J.2
Skyschally, A.3
Heusch, G.4
-
12
-
-
0023199142
-
Mechanism of beneficial effect of β-adrenergic blockade on exercise-induced myocardial ischemia in conscious dogs
-
Guth BD, Heusch G, Seitelberger R, Ross Jr. J. Mechanism of beneficial effect of beta-adrenergic blockade on exercise-induced myocardial ischemia in conscious dogs. Circ Res. 1987 ; 60 (5). 738-746 (Pubitemid 17098139)
-
(1987)
Circulation Research
, vol.60
, Issue.5
, pp. 738-746
-
-
Guth, B.D.1
Heusch, G.2
Seitelberger, R.3
Ross Jr., J.4
-
13
-
-
0025022572
-
α-Adrenergic mechanisms in myocardial ischemia
-
Heusch G. α-Adrenergic mechanisms in myocardial ischemia. Circulation. 1990 ; 81 (1). 1-13
-
(1990)
Circulation
, vol.81
, Issue.1
, pp. 1-13
-
-
Heusch, G.1
-
14
-
-
0034651799
-
α-Adrenergic coronary vasoconstriction and myocardial ischemia in humans
-
Heusch G, Baumgart D, Camici P, et al. α-Adrenergic coronary vasoconstriction and myocardial ischemia in humans. Circulation. 2000 ; 101 (6). 689-694 (Pubitemid 30094742)
-
(2000)
Circulation
, vol.101
, Issue.6
, pp. 689-694
-
-
Heusch, G.1
Baumgart, D.2
Camici, P.3
Chilian, W.4
Gregorini, L.5
Hess, O.6
Indolfi, C.7
Rimoldi, O.8
-
15
-
-
0021207283
-
Nifedipine prevents sympathetic vasoconstriction distal to severe coronary stenoses
-
Heusch G, Deussen A. Nifedipine prevents sympathetic vasoconstriction distal to severe coronary stenoses. J Cardiovasc Pharmacol. 1984 ; 6 (3). 378-383 (Pubitemid 14109185)
-
(1984)
Journal of Cardiovascular Pharmacology
, vol.6
, Issue.3
, pp. 378-383
-
-
Heusch, G.1
Deussen, A.2
-
16
-
-
0023100495
-
Attenuation of exercise-induced myocardial ischemia in dogs with recruitment of coronary vasodilator reserve by nifedipine
-
Heusch G, Guth BD, Seitelberger R, Ross J. Attenuation of exercise-induced myocardial ischemia in dogs with recruitment of coronary vasodilator reserve by nifedipine. Circulation. 1987 ; 75 (2). 482-490 (Pubitemid 17007357)
-
(1987)
Circulation
, vol.75
, Issue.2
, pp. 482-490
-
-
Heusch, G.1
Guth, B.D.2
Seitelberger, R.3
Ross Jr., J.4
-
17
-
-
0026516036
-
Myocardial stunning: A role for calcium antagonists during ischaemia?
-
Heusch G. Myocardial stunning: a role for calcium antagonists during ischaemia?. Cardiovasc Res. 1992 ; 26 (1). 14-19
-
(1992)
Cardiovasc Res
, vol.26
, Issue.1
, pp. 14-19
-
-
Heusch, G.1
-
18
-
-
20444457018
-
f inhibitors as specific heart-rate-reducing agents
-
DOI 10.1038/ncpcardio0052
-
Borer JS. Drug insight: If inhibitors as specific heart-rate-reducing agents. Nature. 2004 ; 1 (2). 103-109 (Pubitemid 40823707)
-
(2004)
Nature Clinical Practice Cardiovascular Medicine
, vol.1
, Issue.2
, pp. 103-109
-
-
Borer, J.S.1
-
19
-
-
4544344025
-
f current inhibition with ivabradine: A new therapeutic perspective in cardiovascular disease
-
DOI 10.2165/00003495-200464160-00003
-
DiFrancesco D, Camm JA. Heart rate lowering by specific and selective If current inhibition with ivabradine. A new therapeutic perspective in cardiovascular disease. Drugs. 2004 ; 64 (16). 1757-1765 (Pubitemid 39215187)
-
(2004)
Drugs
, vol.64
, Issue.16
, pp. 1757-1765
-
-
DiFrancesco, D.1
Camm, J.A.2
-
20
-
-
0023127099
-
Elimination of exercise-induced regional myocardial dysfunction by a bradycardiac agent in dogs with chronic coronary stenosis
-
Guth BD, Heusch G, Seitelberger R, Ross J. Elimination of exercise-induced regional myocardial dysfunction by a bradycardic agent in dogs with chronic coronary stenosis. Circulation. 1987 ; 75 (3). 661-669 (Pubitemid 17026059)
-
(1987)
Circulation
, vol.75
, Issue.3
, pp. 661-669
-
-
Guth, B.D.1
Heusch, G.2
Seitelberger, R.3
Ross Jr., J.4
-
21
-
-
11144356194
-
f Current Inhibitor Ivabradine Improves Left Ventricular Function and Intrinsic Myocardial Structure in Congestive Heart Failure
-
DOI 10.1161/01.CIR.0000118464.48959.1C
-
Mulder P, Barbier S, Chagraoui A, et al. Long-term heart rate reduction induced by the selective If current inhibitor ivabradine improves left ventricular function and intrinsic myocardial structure in congestive heart failure. Circulation. 2004 ; 109 (13). 1674-1679 (Pubitemid 38451726)
-
(2004)
Circulation
, vol.109
, Issue.13
, pp. 1674-1679
-
-
Mulder, P.1
Barbier, S.2
Chagraoui, A.3
Richard, V.4
Henry, J.P.5
Lallemand, F.6
Renet, S.7
Lerebours, G.8
Mahlberg-Gaudin, F.9
Thuillez, C.10
-
22
-
-
34547121963
-
Preservation of coronary reserve by ivabradine-induced reduction in heart rate in infarcted rats is associated with decrease in perivascular collagen
-
Dedkov EI, Zheng W, Christensen LP, Weiss RM, Mahlberg-Gaudin F, Tomanek RJ. Preservation of coronary reserve by ivabradine-induced reduction in heart rate in infarcted rats is associated with decrease in perivascular collagen. Am J Physiol Heart Circ Physiol. 2007 ; 293 (1). H590-H598
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
, Issue.1
-
-
Dedkov, E.I.1
Zheng, W.2
Christensen, L.P.3
Weiss, R.M.4
Mahlberg-Gaudin, F.5
Tomanek, R.J.6
-
23
-
-
0037448788
-
Antianginal and antiischemic effects of ivabradine, an if inhibitor, in stable angina
-
Borer JS, Fox K, Jaillon P, Lerebours G. Antianginal and antiischemic effects of ivabradine, an If inhibitor, in stable angina. Circulation. 2003 ; 107 (6). 817-823
-
(2003)
Circulation
, vol.107
, Issue.6
, pp. 817-823
-
-
Borer, J.S.1
Fox, K.2
Jaillon, P.3
Lerebours, G.4
-
24
-
-
27944492366
-
f inhibitor, compared with atenolol in patients with chronic stable angina
-
DOI 10.1093/eurheartj/ehi586
-
Tardif J-C, Ford I, Tendera M, Bourassa MG, Fox K. Efficacy of ivabradine, a new selective If inhibitor, compared with atenolol in patients with chronic stable angina. Eur Heart J. 2005 ; 26 (23). 2529-2536 (Pubitemid 41677303)
-
(2005)
European Heart Journal
, vol.26
, Issue.23
, pp. 2529-2536
-
-
Tardif, J.-C.1
Ford, I.2
Tendera, M.3
Bourassa, M.G.4
Fox, K.5
-
25
-
-
33947233212
-
Antianginal efficacy and safety of ivabradine compared with amlodipine in patients with stable effort angina pectoris: A 3-month randomised, double-blind, multicentre, noninferiority trial
-
DOI 10.2165/00003495-200767030-00005
-
Ruzyllo W, Tendera M, Ford I, Fox KM. Antianginal efficacy and safety of ivabradine compared with amlodipine in patients with stable effort angina pectoris: a 3-month randomised, double-blind, multicentre, noninferiority trial. Drugs. 2007 ; 67 (3). 393-405 (Pubitemid 46425552)
-
(2007)
Drugs
, vol.67
, Issue.3
, pp. 393-405
-
-
Ruzyllo, W.1
Tendera, M.2
Ford, I.3
Fox, K.M.4
-
26
-
-
63349103473
-
Efficacy of the I(f) current inhibitor ivabradine in patients with chronic stable angina receiving beta-blocker therapy: A 4-month, randomized, placebo-controlled trial
-
Tardif JC, Ponikowski P, Kahan T. Efficacy of the I(f) current inhibitor ivabradine in patients with chronic stable angina receiving beta-blocker therapy: a 4-month, randomized, placebo-controlled trial. Eur Heart J. 2009 ; 30 (5). 540-548
-
(2009)
Eur Heart J
, vol.30
, Issue.5
, pp. 540-548
-
-
Tardif, J.C.1
Ponikowski, P.2
Kahan, T.3
-
27
-
-
50649109186
-
Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): A randomised, double-blind, placebo-controlled trial
-
Fox K, Ford I, Steg PG, Tendera M, Ferrari R. Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial. Lancet. 2008 ; 372 (9641). 807-816
-
(2008)
Lancet
, vol.372
, Issue.9641
, pp. 807-816
-
-
Fox, K.1
Ford, I.2
Steg, P.G.3
Tendera, M.4
Ferrari, R.5
-
28
-
-
70349669250
-
Relationship between ivabradine treatment and cardiovascular outcomes in patients with stable coronary artery disease and left ventricular systolic dysfunction with limiting angina: A subgroup analysis of the randomized, controlled BEAUTIFUL trial
-
Fox K, Ford I, Steg PG, Tendera M, Robertson M, Ferrari R. Relationship between ivabradine treatment and cardiovascular outcomes in patients with stable coronary artery disease and left ventricular systolic dysfunction with limiting angina: a subgroup analysis of the randomized, controlled BEAUTIFUL trial. Eur Heart J. 2009 ; 30 (19). 2337-2345
-
(2009)
Eur Heart J
, vol.30
, Issue.19
, pp. 2337-2345
-
-
Fox, K.1
Ford, I.2
Steg, P.G.3
Tendera, M.4
Robertson, M.5
Ferrari, R.6
-
29
-
-
70349659940
-
A BEAUTIFUL lesson-ivabradine protects from ischaemia, but not from heart failure: Through heart rate reduction or more?
-
Heusch G. A BEAUTIFUL lesson-ivabradine protects from ischaemia, but not from heart failure: through heart rate reduction or more?. Eur Heart J. 2009 ; 30 (19). 2300-2301
-
(2009)
Eur Heart J
, vol.30
, Issue.19
, pp. 2300-2301
-
-
Heusch, G.1
-
30
-
-
77956612624
-
Ivabradine and outcomes in chronic heart failure (SHIFT): A randomised placebo-controlled study
-
Swedberg K, Komajda M, Böhm M, et al. Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study. Lancet. 2010 ; 376 (9744). 875-885
-
(2010)
Lancet
, vol.376
, Issue.9744
, pp. 875-885
-
-
Swedberg, K.1
Komajda, M.2
Böhm, M.3
-
31
-
-
0034975369
-
F in human ventricular myocytes are modulated by cardiac disease
-
DOI 10.1006/jmcc.2000.1316
-
Cerbai E, Sartiani L, DePaoli P, et al. The properties of the pacemaker current If in human ventricular myocytes are modulated by cardiac disease. J Mol Cell Cardiol. 2001 ; 33 (3). 441-448 (Pubitemid 32539001)
-
(2001)
Journal of Molecular and Cellular Cardiology
, vol.33
, Issue.3
, pp. 441-448
-
-
Cerbai, E.1
Sartiani, L.2
DePaoli, P.3
Pino, R.4
Maccherini, M.5
Bizzarri, F.6
DiCiolla, F.7
Davoli, G.8
Sani, G.9
Mugelli, A.10
-
32
-
-
44449137886
-
f at physiological calcium concentrations
-
DOI 10.1093/cvr/cvn032
-
Michels G, Brandt MC, Zagidullin N, et al. Direct evidence for calcium conductance of hyperpolarization-activated cyclic nucleotide-gated channels and human native If at physiological calcium concentrations. Cardiovasc Res. 2008 ; 78 (3). 466-475 (Pubitemid 351769763)
-
(2008)
Cardiovascular Research
, vol.78
, Issue.3
, pp. 466-475
-
-
Michels, G.1
Brandt, M.C.2
Zagidullin, N.3
Khan, I.F.4
Larbig, R.5
Van Aaken, S.6
Wippermann, J.7
Hoppe, U.C.8
-
33
-
-
79955657779
-
The in-situ pig heart with regional ischemia/reperfusion-ready for translation
-
Heusch G, Skyschally A, Schulz R. The in-situ pig heart with regional ischemia/reperfusion-ready for translation. J Mol Cell Cardiol. 2011 ;:
-
(2011)
J Mol Cell Cardiol
-
-
Heusch, G.1
Skyschally, A.2
Schulz, R.3
-
34
-
-
59649114814
-
Ischemic postconditioning in pigs: No causal role for RISK activation
-
Skyschally A, van Caster P, Boengler K, et al. Ischemic postconditioning in pigs: no causal role for RISK activation. Circ Res. 2009 ; 104 (1). 15-18
-
(2009)
Circ Res
, vol.104
, Issue.1
, pp. 15-18
-
-
Skyschally, A.1
Van Caster, P.2
Boengler, K.3
-
35
-
-
70349665133
-
Ischemic postconditioning-experimental models and protocol algorithms
-
Skyschally A, van Caster P, Iliodromitis EK, Schulz R, Kremastinos DT, Heusch G. Ischemic postconditioning-experimental models and protocol algorithms. Basic Res Cardiol. 2009 ; 104 (5). 469-483
-
(2009)
Basic Res Cardiol
, vol.104
, Issue.5
, pp. 469-483
-
-
Skyschally, A.1
Van Caster, P.2
Iliodromitis, E.K.3
Schulz, R.4
Kremastinos, D.T.5
Heusch, G.6
|