Quantifying the effect of pore size and surface treatment on epidermal incorporation into percutaneously implanted sphere-templated porous biomaterials in mice

Journal of Biomedical Materials Research - Part A

Volumn 98 A, Issue 4, 2011, Pages 499-508

  Underwood, Robert A ^a   Usui, Marcia L ^a   Zhao, Ge ^a   Hauch, Kip D ^b   Takeno, Marc M ^b   Ratner, Buddy D ^b,c   Marshall, Andrew J ^d   Shi, Xuefeng ^a   Olerud, John E ^a   Fleckman, Philip ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b University of Washington   (United States)

^c University of Washington   (United States)

^d Healionics Inc   (United States)

Author keywords

epidermal migration; mouse model; percutaneous implant; porous biomaterial; quantification

Indexed keywords

EPIDERMAL MIGRATION; MOUSE MODELS; PERCUTANEOUS IMPLANT; POROUS BIOMATERIAL; QUANTIFICATION;

BIOLOGICAL MATERIALS; BIOMATERIALS; BIOMEDICAL ENGINEERING; INTEGRATION; MAMMALS; PORE SIZE; SPHERES;

SURFACE TREATMENT;

BIOMATERIAL; POLY (2 HYDROXYETHYLMETHACRYLATE); UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; EFFECT SIZE; EPIDERMIS; EPITHELIUM; HEALING; IMAGE ANALYSIS; IMPLANT; KERATINOCYTE; MALE; MOUSE; NONHUMAN; SURFACE PROPERTY;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELL MOVEMENT; EPIDERMIS; IMPLANTS, EXPERIMENTAL; KERATINOCYTES; MALE; MATERIALS TESTING; METHACRYLATES; MICE; MICE, INBRED C57BL; POROSITY; SURFACE PROPERTIES;

EID: 80051474127     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.33125     Document Type: Article

References (27)

1. Safdar N, Kluger DM, Maki DG,. A review of risk factors for catheter-related bloodstream infection caused by percutaneously inserted, noncuffed central venous catheters: implications for preventive strategies. Medicine (Baltimore) 2002; 81: 466-479. (Pubitemid 35285966)
2. Fleckman P, Olerud JE,. Models for the histologic study of the skin interface with percutaneous biomaterials. Biomed Mater 2008; 3: 034006.
3. Fukano Y, Knowles NG, Usui ML, Underwood RA, Hauch KD, Marshall AJ, Ratner BD, Giachelli C, Carter WG, Fleckman P, Olerud JE,. Characterization of an in vitro model for evaluating the interface between skin and percutaneous biomaterials. Wound Repair Regen 2006; 14: 484-491. (Pubitemid 44266607)
4. Fukano Y, Usui ML, Underwood RA, Isenhath S, Marshall AJ, Hauch KD, Ratner BD, Olerud JE, Fleckman P,. Epidermal and dermal integration into sphere-templated porous poly(2-hydroxyethyl methacrylate) implants in mice. J Biomed Mater Res A 2010; 94: 1172-1186.
5. Isenhath SN, Fukano Y, Usui ML, Underwood RA, Irvin CA, Marshall AJ, Hauch KD, Ratner BD, Fleckman P, Olerud JE,. A mouse model to evaluate the interface between skin and a percutaneous device. J Biomed Mater Res A 2007; 83: 915-922. (Pubitemid 350231751)
6. Knowles NG, Miyashita Y, Usui ML, Marshall AJ, Pirrone A, Hauch KD, Ratner BD, Underwood RA, Fleckman P, Olerud JE,. A model for studying epithelial attachment and morphology at the interface between skin and percutaneous devices. J Biomed Mater Res A 2005; 74: 482-488. (Pubitemid 41140588)
7. Odland G, Ross R,. Human wound repair. I. Epidermal regeneration. J Cell Biol 1968; 39: 135-151.
8. Olerud JE, Gown AM, Bickenbach J, Dale B, Odland GF,. An assessment of human epidermal repair in elderly normal subjects using immunohistochemical methods. J Invest Dermatol 1988; 90: 845-850.
9. Marshall AJ,. Porous hydrogels with well-defined pore structure for biomaterials applications. PhD dissertation, University of Washington, 2004.
10. Marshall AJ, Ratner BD,. A new technique for fabrication of macroporous hydogels. Transactions of the Society for Biomaterials 2001.
11. Marshall AJ, Ratner BD,. Porous hydogel scaffolds for tissue engineering. 2002.
12. Marshall AJ, Ratner BD,. Quantitative characterization of sphere-templated porous biomaterials. AIChE J 2005; 51: 1221-1232. (Pubitemid 40554084)
13. Vernon RB, Gooden MD,. New technologies in vitro for analysis of cell movement on or within collagen gels. Matrix Biol 2002; 21: 661-669. (Pubitemid 36057132)
14. Vernon RB, Sage EH,. A novel, quantitative model for study of endothelial cell migration and sprout formation within three-dimensional collagen matrices. Microvasc Res 1999; 57: 118-133. (Pubitemid 29393289)
15. von Recum AF,. Applications and failure modes of percutaneous devices: a review. J Biomed Mater Res 1984; 18: 323-336. (Pubitemid 14101917)
16. Winter GD,. Transcutaneous implants: reactions of the skin-implant interface. J Biomed Mater Res 1974; 8: 99-113.
17. Von Recum AF, Park JB,. Permanent percutaneous devices. CRC Crit Rev Bioeng 1981; 5: 37-77.
18. Fitton JH, Dalton BA, Beumer G, Johnson G, Griesser HJ, Steele JG,. Surface topography can interfere with epithelial tissue migration. J Biomed Mater Res 1998; 42: 245-257. (Pubitemid 28446966)
19. Yannas IV, Lee E, Orgill DP, Skrabut EM, Murphy GF,. Synthesis and characterization of a model extracellular matrix that induces partial regeneration of adult mammalian skin. Proc Natl Acad Sci USA 1989; 86: 933-937. (Pubitemid 19056266)
20. Murphy CM, Haugh MG, O'Brien FJ,. The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering. Biomaterials 2010; 31: 461-466.
21. Marshall AJ, Irvin CA, Barker T, Sage EH, Hauch KD, Ratner BD,. Biomaterials with tightly controlled pore size that promote vascular in-growth. Polym Prepr 2004; 45: 100-101.
22. Santoro MM, Gaudino G, Marchisio PC,. The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration. Dev Cell 2003; 5: 257-271. (Pubitemid 37006470)
23. Dovi JV, Szpaderska AM, DiPietro LA,. Neutrophil function in the healing wound: adding insult to injury? Thromb Haemost 2004; 92: 275-280. (Pubitemid 39172307)
24. Briggaman RA, Schechter NM, Fraki J, Lazarus GS,. Degradation of the epidermal-dermal junction by proteolytic enzymes from human skin and human polymorphonuclear leukocytes. J Exp Med 1984; 160: 1027-1042. (Pubitemid 14020965)
25. Usui ML, Underwood RA, Mansbridge JN, Muffley LA, Carter WG, Olerud JE,. Morphological evidence for the role of suprabasal keratinocytes in wound reepithelialization. Wound Repair Regen 2005; 13: 468-479. (Pubitemid 41783165)
26. Underwood RA, Carter WG, Usui ML, Olerud JE,. Ultrastructural localization of integrin subunits beta4 and alpha3 within the migrating epithelial tongue of in vivo human wounds. J Histochem Cytochem 2009; 57: 123-142.
27. Tavakkol Z, Samuelson D, Delancey Pulcini E, Underwood RA, Usui ML, Costerton JW, James GA, Olerud JE, Fleckman P,. Resident bacterial flora in the skin of C57BL/6 mice housed under SPF conditions. J Am Assoc Lab Anim Sci 2010; 49: 588-591.