Atropine in ameliorating the progression of myopia in children with mild to moderate myopia: A meta-analysis of controlled clinical trials

Journal of Ocular Pharmacology and Therapeutics

Volumn 27, Issue 4, 2011, Pages 361-368

  Song, Yan Yan ^a   Wang, Hao ^a   Wang, Bai Song ^a   Qi, Hong ^a   Rong, Zheng Xing ^a   Chen, Hong Zhuan ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE;

ALLERGIC BLEPHARITIS; ARTICLE; BEDTIME DOSAGE; CHILDHOOD DISEASE; DISEASE COURSE; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; EVENING DOSAGE; GLARE; HUMAN; LENS; LOW DRUG DOSE; META ANALYSIS; MYOPIA; OUTCOME ASSESSMENT; PHOTOPHOBIA; RANDOMIZED CONTROLLED TRIAL (TOPIC); SIDE EFFECT; SYSTEMATIC REVIEW; TREATMENT DURATION;

ADOLESCENT; ATROPINE; CHILD; CHILD, PRESCHOOL; CONTROLLED CLINICAL TRIALS AS TOPIC; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; FOLLOW-UP STUDIES; HUMANS; MYDRIATICS; MYOPIA; OPHTHALMIC SOLUTIONS; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES;

EID: 79961200058     PISSN: 10807683     EISSN: 15577732     Source Type: Journal    
DOI: 10.1089/jop.2011.0017     Document Type: Article

References (39)

1. Sperduto, R.D., Seigel, D., Roberts, J., and Rowland, M. Prevalence of myopia in the United States. Arch Ophthalmol. 101:405-407, 1983. (Pubitemid 13152589)
2. Wang, Q., Klein, B.E., Klein, R., and Moss, S.E. Refractive status in the Beaver Dam Eye Study. Invest. Ophthalmol. Vis. Sci. 35:4344-4347, 1994. (Pubitemid 24377506)
3. The Framingham Offspring Eye Study Group. Familial aggregation and prevalence of myopia in the Framingham Offspring Eye Study. Arch Ophthalmol. 114:326-332, 1996.
4. Fan, D.S., Lam, D.S., Lam, R.F., Lau, J.T., Chong, K.S., Cheung, E.Y., Chew, S.J., et al. Prevalence, incidence, and progression of myopia of school children in Hong Kong. Invest. Ophthalmol. Vis. Sci. 45:1071-1075, 2004. (Pubitemid 38869009)
5. Lim, H.C., Quah, B.L., Balakrishnan, V., Lim, H.C., Tay, V., and Emmanuel, S.C. Vision screening of 4-year-old children in Singapore. Singapore Med. J. 41:271-278, 2000.
6. Wong, T.Y., Foster, P.J., Hee, J., Ng, T.P., Tielsch, J.M., Chew, S.J., et al. Prevalence and risk factors for refractive errors in adult Chinese in Singapore. Invest. Ophthalmol. Vis. Sci. 41:2486-2494, 2000. (Pubitemid 30624374)
7. Lin, L.L.K., Shih, Y.F., Hsiao, C.K., and Chen, C.J. Prevalence of Myopia in Taiwanese Schoolchildren: 1983 to 2000. Ann. Acad. Med. 33:27-33, 2004. (Pubitemid 38478105)
8. Cheng, D., Schmid, K.L., and Woo, G.C. Myopia prevalence in Chinese-Canadian children in an optometric practice. Optom. Vis. Sci. 84:21-32, 2007. (Pubitemid 46105017)
9. Seet, B., Wong, T.Y., Tan, D.T., Saw, S.M., Balakrishnan, V., Lee, L.K., et al. Myopia in Singapore: Taking a public health approach. Br. J. Ophthalmol. 85:521-526, 2001. (Pubitemid 32397820)
10. Rose, K., Smith, W., Morgan, I., and Mitchell, P. The increasing prevalence of myopia: Implications for Australia. Clin. Exp. Ophthalmol. 29:116-120, 2001. (Pubitemid 32618970)
11. Rose, K.A., Morgan, I.G., Smith, W., and Mitchell, P. High heritability of myopia does not preclude rapid changes in prevalence. Clin. Exp. Ophthalmol. 30:168-172, 2002. (Pubitemid 34578162)
12. Thorn, F., Gwiazda, J., and Held, R. Myopia progression is specified by a double exponential growth function. Optom Vis. Sci. 82:286-297, 2005. (Pubitemid 40546186)
13. Tan, N.W., Saw, S.M., Lam, D.S., Cheng, H.M., Rajan, U., and Chew, S.J. Temporal variations in myopia progression in Singaporean children within an academic year. Optom. Vis. Sci. 77:465-472, 2000.
14. Rada, J.A., Shelton, S., and Norton, T.T. The sclera and myopia. Exp. Eye Res. 82:185-200, 2006. (Pubitemid 43122105)
15. Saw, S.M., Gazzard, G., Shih-Yen, E.C., and Chua, W.H. Myopia and associated pathological complications. Ophthalmic Physiol. Opt. 25:381-391, 2005. (Pubitemid 41710971)
16. Tano, Y. Pathologic myopia: Where are we now? Am. J. Ophthalmol. 134:645-660, 2002. (Pubitemid 35300382)
17. Goss, D.A. Attempts to reduce the rate of increase of myopia in young people-a critical literature review. Am. J. Optom. Physiol. Opt. 59:828-841, 1982. (Pubitemid 13205631)
18. Diether, S., Schaeffel, F., Lambrou, G.N., Fritsch, C., and Trendelenburg, A.U. Effects of intravitreally and intraperitoneally injected atropine on two types of experimental myopia in chicken. Exp. Eye Res. 84:266-274, 2007. (Pubitemid 44958466)
19. Luu, C.D., Lau, A.M., Koh, A.H., and Tan, D. Multifocal electroretinogram in children on atropine treatment for myopia. Br. J. Ophthalmol. 89:151-153, 2005. (Pubitemid 40175209)
20. Chua, W.H., Balakrishnan, V., Chan, Y.H., Tong, L., Ling, Y., Quah, B.L., et al. Atropine for the treatment of childhood myopia. Ophthalmology 113:2285-2291, 2006. (Pubitemid 44838909)
21. Fan, D.S., Lam, D.S., Chan, C.K., Fan, A.H., Cheung, E.Y., and Rao, S.K. Topical atropine in retarding myopic progression and axial length growth in children with moderate to severe myopia: A pilot study. Jpn. J. Ophthalmol. 51:27-33, 2007. (Pubitemid 46281227)
22. Lee, J.J., Fang, P.C., Yang, I.H., Chen, C.H., Lin, P.W., Lin, S.A., et al. Prevention of myopia progression with 0.05% atropine solution. J. Ocul. Pharmacol. Ther. 22:41-46, 2006.
23. Shih, Y.F., Chen, C.H., Chou, A.C., Ho, T.C., Lin, L.L., and Hung, P.T. Effects of different concentrations of atropine on controlling myopia in myopic children. J. Ocul. Pharmacol. Ther. 15:85-90, 1999. (Pubitemid 29072597)
24. Hsiao, C.K., Tsai, M.Y., and Chen, H.M. Inference of nested variance components in a longitudinal myopia intervention trial. Stat. Med. 24:3251-3267, 2005. (Pubitemid 41548979)
25. Yen, M.Y., Liu, J.H., Kao, S.C., and Shiao, C.H. Comparison of the effect of atropine and cyclopentolate on myopia. Ann. Ophthalmol. 21:180-182, 187, 1989.
26. Kao, S.C., Lu, H.Y., and Liu, J.H. Atropine effect on school myopia. A preliminary report. Acta Ophthalmol. Suppl. 185:132-133, 1988.
27. Chiang, M.F., Kouzis, A., Pointer, R.W., and Repka, M.X. Treatment of childhood myopia with atropine eyedrops and bifocal spectacles. Binocul. Vis. Strabismus Q. 16:209-215, 2001.
28. Saw, S.M., Shih-Yen, E.C., Koh, A., and Tan, D. Interventions to retard myopia progression in children: An evidencebased update. Ophthalmology 109:415-421, 2002. (Pubitemid 34184903)
29. Whitehead, A. Meta-Analysis of Controlled Clinical Trials. Chichester: John Wiley & Sons Ltd; 2002.
30. Egger, M., Davey Smith, G., Schneider, M., and Minder, C. Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629-634, 1997. (Pubitemid 27387172)
31. Berkey, C.S., Hoaglin, D.C., Mosteller, F., and Colditz, G.A. A random-effects regression model for meta-analysis. Stat. Med. 14:395-411, 1995.
32. Liang, C.K., Ho, T.Y., Li, T.C., Hsu, W.M., Li, T.M., Lee, Y.C., et al. A combined therapy using stimulating auricular acupoints enhances lower-level atropine eyedrops when used for myopia control in school-aged children evaluated by a pilot randomized controlled clinical trial. Complement Ther. Med. 16:305-310, 2008.
33. Schwartz, J.T. Results of a monozygotic cotwin control study on a treatment for myopia. Prog. Clin. Biol. Res. 69:249-258, 1981.
34. Goss, D.A.Effectofbifocal lensesonthe rateof childhoodmyopia progression.Am. J. Optom. Physiol. Opt. 63:135-141, 1986.
35. Goss, D.A. Overcorrection as a means of slowing myopic progression. Am. J. Optom. Physiol. Opt. 61:85-93, 1984. (Pubitemid 14170977)
36. Tong, L., Huang, X.L., Koh, A.L., Zhang, X., Tan, D.T., and Chua, W.H. Atropine for the treatment of childhood myopia: Effect on myopia progression after cessation of atropine. Ophthalmology 116:572-579, 2009.
37. Kennedy, R.H., Dyer, J.A., Kennedy, M.A., Parulkar, S., Kurland, L.T., Herman, D.C., et al. Reducing the progression of myopia with atropine: A long term cohort study of Olmsted County students. Binocul. Vis. Strabismus Q. 15:281-304, 2000.
38. Carlson, M.D., and Morrison, R.S. Study design, precision, and validity in observational studies. J. Palliat. Med. 12:77-82, 2009.
39. Concato, J., Shah, N., and Horwitz, R.I. Randomized, controlled trials, observational studies, and the hierarchy of research designs. N. Engl. J. Med. 342:1887-1892, 2000. (Pubitemid 30419054)