Effect of actinomycin D and cycloheximide on human sperm function

Archives of Andrology

Volumn 41, Issue 2, 1998, Pages 135-142

  Naz, R K ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Capacitation; Haploid gene expression; Human sperm; Transcription; Translation

Indexed keywords

CYCLOHEXIMIDE; DACTINOMYCIN;

ACROSOME REACTION; ARTICLE; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SEMEN ANALYSIS; SPERMATOZOON CAPACITATION; SPERMATOZOON PENETRATION; TRANSLATION REGULATION;

EID: 79961184084     PISSN: 01485016     EISSN: None     Source Type: Journal    
DOI: 10.3109/01485019808987955     Document Type: Article

References (24)

1. Ahmad K, Naz RK (1995): Thymosin alpha-1 and FA-1 monoclonal antibody affect fertilizing capacity of human sperm by modulating protein phosphorylation pattern. J Reprod Immunol 29:1-17.
2. Byrd W, Tsu J, Wolf D (1989): Kinetics of spontaneous and induced acrosomal loss in human sperm incubated under capacitating and non-capacitating conditions. Gamete Res 22:109-122.
3. Gatewood JM, Cook GR, Balhorn R, Bradbury EM, Schnid CW (1987): Sequence specific packaging of DNA in human sperm chromatin. Science 236:962-984.
4. Jager S, Kinken J, Kremer J (1984): Triple staining of human sperm: technical aspects. Arch Androl 12:53-58.
5. Kumar G, Patel D, Naz RK (1993): cMyc mRNA is present in human sperm cells. Cell Mol Bio Res 39:111-117.
6. Laemmli UK (1970): Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227:680-685.
7. Lin S-Y, Mosterller RD, Hardesty B (1966): The mechanism of sodium fluoride and cycloheximide inhibition of hemoglobin biosynthesis in the cell-free reticulocyte system. J Mol Biol 21:51-69.
8. Meienhofer J, Alterton E (1973): Structure-activity relationships in the actinomycins. Adv Appl Microbiol 16:203-300.
9. Naz RK (1987): Involvement of fertilization antigen (FA-1) in involuntary immunoinfertility in human. J Clin Invest 80:1375-1383.
10. Naz RK (1996): Involvement of protein tyrosine phosphorylation of human sperm in capacitation/ acrosome reaction and zona pellucida binding. Front Biosci 1:206-213.
11. Naz RK, Ahmad K (1994): Molecular identities of human sperm proteins that bind human zona pellucida: nature of sperm-zona interaction, tyrosine kinase activity and involvement of FA-1. Mol Reprod Dev 39:397-408.
12. Naz RK, Ahmad K, Kaplan P (1993): Involvement of cyclins and cdc2 serine/threonine protein kinase in human sperm cell function. Biol Reprod 48:720-728.
13. Naz, RK, Ahmad K, Menge AC (1993): Antiidiotypic antibodies to sperm in sera of fertile women that neutralize antisperm antibodies. J Clin Invest 92:2331-2338.
14. Naz, RK, Kaplan P, Goldstein AL (1992): Thymosin alpha-1 enhances the fertilizing capacity of human sperm cell: implication in diagnosis and treatment of male infertility. Biol Reprod 47:1064-1072.
15. Naz, RK, Kumar R (1991): Transforming growth factor β1 enhances expression of 50 kDa protein related to 2',5'-oligoadenylate synthetase in human sperm cells. J Cell Physiol 146:156-163.
16. Obrig TG, Culp WJ, McKeehan WL, Hardesty B (1971): The mechanism by which cycloheximide and related glutarimide antibiotics inhibit peptide synthesis on reticulocyte ribosomes. J Biol Chem 246:174-181.
17. Pescott CA, Brito M, Figuera J, Concha II, Yanez A, Burzio LO (1989): Presence of RNA in sperm nucleus. Biochem Biophys Res Commun 158:272-278.
18. Rajaniemi HJ, Midgley AR Jr (1975): Autoradiographic techniques for localizing protein hormones in target tissues. Methods Enzymol 37:147-167.
19. Ward SW, Coffey DS (1991): DNA packaging and organization in mammalian spermatozoa: Com parison with somatic cells. Biol Reprod 44:569-574.
20. Ward SW, Zalensky AO (1996): The unique, complex organization of the transcriptionally silent sperm chromatin. Crit Rev Eukaryot Gene Expr 6:139-147.
21. Wilson DW, Jones RL (1981): Intercalating drugs: DNA binding and molecular pharmacology. Adv Pharm Chemo 18:177-222.
22. Witkin SS, Korngold GC, Bendich A (1975): Ribonuclease-sensitive DNA synthesizing complex in human sperm heads and seminal fluid. Proc Natl Acad Sci USA 72:3295-3299.
23. Yanagimachi R (1994): Mammalian fertilization. In: The physiology of Reproduction, Vol 1. Knobil E, Neill JD (Eds). New York: Raven, pp 189-318.
24. Zhu X, Naz RK (1997): Fertilization antigen-1: cDNA cloning, testis-specific expression and immunocontraceptive effects. Proc Natl Acad Sci USA 94:4704-4709.