Identification of circulatory and excretory metabolites of a novel nitric oxide donor ZJM-289 in rat plasma, bile, urine and faeces by liquid chromatographytandem mass spectrometry

Xenobiotica

Volumn 41, Issue 9, 2011, Pages 805-817

  Li, Ning ^a   Wang, Xuliang ^a   Li, Tingting ^a   Ji, Hui ^a   Zhang, Yihua ^a   Qiu, Zhixia ^a   Zhao, Di ^a   Chen, Xijing ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

3 n butylphthalide; ferulic acid; fragmentation pathway; metabolites identification; rat; ZJM 289

Indexed keywords

3 BUTYLPHTHALIDE; [2 (1 DIETHYLAMINOACETOXY)PENTYL]BENZOIC ACID [2 METHOXY 4 [2 (4 NITROOXYBUTOXYCARBONYL)VINYL]] PHENYL ESTER; DRUG METABOLITE; FERULIC ACID; NITRIC OXIDE; NITRIC OXIDE DONOR; UNCLASSIFIED DRUG; ZJM 289;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DRUG METABOLISM; DRUG STRUCTURE; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; TANDEM MASS SPECTROMETRY;

ANIMALS; BILE; CHROMATOGRAPHY, LIQUID; CINNAMATES; FECES; INJECTIONS, INTRAVENOUS; MALE; METABOLIC NETWORKS AND PATHWAYS; NITRATES; NITRIC OXIDE DONORS; RATS; RATS, SPRAGUE-DAWLEY; TANDEM MASS SPECTROMETRY; TIME FACTORS;

RATTUS;

EID: 79961183211     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2011.580385     Document Type: Article

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