MPP +-induced toxicity in the presence of dopamine is mediated by COX-2 through oxidative stress

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 384, Issue 2, 2011, Pages 157-167

  Hsieh, Ya Ching ^a   Mounsey, Ross B ^a   Teismann, Peter ^a,b  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Apoptosis; MPP +; Neuroinflammation; Parkinson's disease; Ventral mesencephalon

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 5,5 DIMETHYL 3 (3 FLUOROPHENYL) 4 (4 METHYLSULPHONYL)PHENYL 2 (5H)FURANONE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DOPAMINE; IBUPROFEN; REACTIVE OXYGEN METABOLITE; RESERPINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME SYNTHESIS; MESENCEPHALON; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; RAT;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DOPAMINE; DOPAMINERGIC NEURONS; IMMUNOHISTOCHEMISTRY; MESENCEPHALON; OXIDATIVE STRESS; PARKINSON DISEASE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 79961173265     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-011-0660-8     Document Type: Article

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