메뉴 건너뛰기




Volumn 301, Issue 2, 2011, Pages

Regulation of serum 1,25(OH)2vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4

Author keywords

FGF23; Phosphate; Proximal tubule

Indexed keywords

CALCITRIOL; FIBROBLAST GROWTH FACTOR 23; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 3; FIBROBLAST GROWTH FACTOR RECEPTOR 4; PARATHYROID HORMONE; PHOSPHORUS; RECOMBINANT FIBROBLAST GROWTH FACTOR; RECOMBINANT FIBROBLAST GROWTH FACTOR 23; UNCLASSIFIED DRUG;

EID: 79961141521     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00740.2010     Document Type: Article
Times cited : (85)

References (51)
  • 1
    • 0028331157 scopus 로고
    • Maturational effects of glucocorticoids on neonatal brush-border membrane phosphate transport
    • Arar M, Levi M, Baum M. Maturational effects of glucocorticoids on neonatal brush-border membrane phosphate transport. Pediatr Res 35: 474-478, 1994.
    • (1994) Pediatr Res , vol.35 , pp. 474-478
    • Arar, M.1    Levi, M.2    Baum, M.3
  • 2
    • 0041314064 scopus 로고    scopus 로고
    • Disordered regulation of renal 25-hydroxyvitamin D-1alpha-hydroxylase gene expression by phosphorus in X-linked hypophosphatemic (hyp) mice
    • Azam N, Zhang MY, Wang X, Tenenhouse HS, Portale AA. Disordered regulation of renal 25-hydroxyvitamin D-1alpha-hydroxylase gene expression by phosphorus in X-linked hypophosphatemic (hyp) mice. Endocrinology 144: 3463-3468, 2003.
    • (2003) Endocrinology , vol.144 , pp. 3463-3468
    • Azam, N.1    Zhang, M.Y.2    Wang, X.3    Tenenhouse, H.S.4    Portale, A.A.5
  • 3
    • 32644468920 scopus 로고    scopus 로고
    • Effect of fibroblast growth factor-23 on phosphate transport in proximal tubules
    • Baum M, Schiavi S, Dwarakanath V, Quigley R. Effect of fibroblast growth factor-23 on phosphate transport in proximal tubules. Kidney Int 68: 1148-1153, 2005.
    • (2005) Kidney Int , vol.68 , pp. 1148-1153
    • Baum, M.1    Schiavi, S.2    Dwarakanath, V.3    Quigley, R.4
  • 4
    • 0016706847 scopus 로고
    • Renal phosphate transport: Inhomogeneity of local proximal transport rates and sodium dependence
    • Baumann K, de Rouffignac C, Roinel N, Rumrich G, Ullrich KJ. Renal phosphate transport: inhomogeneity of local proximal transport rates and sodium dependence. Pflügers Arch 356: 287-298, 1975.
    • (1975) Pflügers Arch , vol.356 , pp. 287-298
    • Baumann, K.1    de Rouffignac, C.2    Roinel, N.3    Rumrich, G.4    Ullrich, K.J.5
  • 5
    • 61649100307 scopus 로고    scopus 로고
    • The FGF family: Biology, pathophysiology and therapy
    • Beenken A, Mohammadi M. The FGF family: biology, pathophysiology and therapy. Nat Rev Drug Discov 8: 235-253, 2009.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 235-253
    • Beenken, A.1    Mohammadi, M.2
  • 7
    • 0018117137 scopus 로고
    • Site of 1,25(OH)2 vitamin D3 synthesis in the kidney
    • Brunette MG, Chan M, Ferriere C, Roberts KD. Site of 1,25(OH)2 vitamin D3 synthesis in the kidney. Nature 276: 287-289, 1978.
    • (1978) Nature , vol.276 , pp. 287-289
    • Brunette, M.G.1    Chan, M.2    Ferriere, C.3    Roberts, K.D.4
  • 8
    • 23444447617 scopus 로고
    • Brief report: Inhibition of renal phosphate transport by a tumor product in a patient with oncogenic osteomalacia
    • Cai Q, Hodgson SF, Kao PC, Lennon VA, Klee GG, Zinsmiester AR, Kumar R. Brief report: inhibition of renal phosphate transport by a tumor product in a patient with oncogenic osteomalacia. N Engl J Med 330: 1645-1649, 1994.
    • (1994) N Engl J Med , vol.330 , pp. 1645-1649
    • Cai, Q.1    Hodgson, S.F.2    Kao, P.C.3    Lennon, V.A.4    Klee, G.G.5    Zinsmiester, A.R.6    Kumar, R.7
  • 9
    • 0028363099 scopus 로고
    • Tumor-induced osteomalacia-unveiling a new hormone
    • Econs MJ, Drezner MK. Tumor-induced osteomalacia-unveiling a new hormone. N Engl J Med 330: 1679-1681, 1994.
    • (1994) N Engl J Med , vol.330 , pp. 1679-1681
    • Econs, M.J.1    Drezner, M.K.2
  • 11
    • 65649103814 scopus 로고    scopus 로고
    • Initial FGF23-mediated signaling occurs in the distal convoluted tubule
    • Farrow EG, Davis SI, Summers LJ, White KE. Initial FGF23-mediated signaling occurs in the distal convoluted tubule. J Am Soc Nephrol 20: 955-960, 2009.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 955-960
    • Farrow, E.G.1    Davis, S.I.2    Summers, L.J.3    White, K.E.4
  • 13
    • 0014958183 scopus 로고
    • Unique biosynthesis by kidney of a biological active vitamin D metabolite
    • Fraser DR, Kodicek E. Unique biosynthesis by kidney of a biological active vitamin D metabolite. Nature 228: 764-766, 1970.
    • (1970) Nature , vol.228 , pp. 764-766
    • Fraser, D.R.1    Kodicek, E.2
  • 15
    • 77951259224 scopus 로고    scopus 로고
    • Regulation of phosphate transport by fibroblast growth factor 23 (FGF23): Implications for disorders of phosphate metabolism
    • Gattineni J, Baum M. Regulation of phosphate transport by fibroblast growth factor 23 (FGF23): implications for disorders of phosphate metabolism. Pediatr Nephrol 25: 591-601, 2010.
    • (2010) Pediatr Nephrol , vol.25 , pp. 591-601
    • Gattineni, J.1    Baum, M.2
  • 17
    • 0027050480 scopus 로고
    • Complexity of FGF receptors: Genetic basis for structural diversity and functional specificity
    • Givol D, Yayon A. Complexity of FGF receptors: genetic basis for structural diversity and functional specificity. FASEB J 6: 3362-3369, 1992.
    • (1992) FASEB J , vol.6 , pp. 3362-3369
    • Givol, D.1    Yayon, A.2
  • 19
    • 34447514029 scopus 로고    scopus 로고
    • Vitamin D deficiency
    • Holick MF. Vitamin D deficiency. N Engl J Med 357: 266-281, 2007.
    • (2007) N Engl J Med , vol.357 , pp. 266-281
    • Holick, M.F.1
  • 21
    • 0029160578 scopus 로고
    • A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets
    • HYP Consortium
    • HYP Consortium. A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. Nat Genet 11: 130-136, 1995.
    • (1995) Nat Genet , vol.11 , pp. 130-136
  • 22
    • 4744372082 scopus 로고    scopus 로고
    • Evolution of the Fgf and Fgfr gene families
    • Itoh N, Ornitz DM. Evolution of the Fgf and Fgfr gene families. Trends Genet 20: 563-569, 2004.
    • (2004) Trends Genet , vol.20 , pp. 563-569
    • Itoh, N.1    Ornitz, D.M.2
  • 23
    • 0026649742 scopus 로고
    • Fibroblast growth factor receptor tyrosine kinases: Molecular analysis and signal transduction
    • Jaye M, Schlessinger J, Dionne CA. Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction. Biochim Biophys Acta 1135: 185-199, 1992.
    • (1992) Biochim Biophys Acta , vol.1135 , pp. 185-199
    • Jaye, M.1    Schlessinger, J.2    Dionne, C.A.3
  • 27
    • 79952161016 scopus 로고    scopus 로고
    • Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype
    • Li H, Martin AC, David V, Quarles LD. Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype. Am J Physiol Endocrinol Metab 300: E508-E517, 2011.
    • (2011) Am J Physiol Endocrinol Metab , vol.300
    • Li, H.1    Martin, A.C.2    David, V.3    Quarles, L.D.4
  • 28
    • 13844318061 scopus 로고    scopus 로고
    • Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice
    • Li SA, Watanabe M, Yamada H, Nagai A, Kinuta M, Takei K. Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice. Cell Struct Funct 29: 91-99, 2004.
    • (2004) Cell Struct Funct , vol.29 , pp. 91-99
    • Li, S.A.1    Watanabe, M.2    Yamada, H.3    Nagai, A.4    Kinuta, M.5    Takei, K.6
  • 30
    • 0020683390 scopus 로고
    • Abnormal regulation of renal 25-hydroxyvi-tamin D-1 alpha-hydroxylase activity in the X-linked hypophosphatemic mouse
    • Lobaugh B, Drezner MK. Abnormal regulation of renal 25-hydroxyvi-tamin D-1 alpha-hydroxylase activity in the X-linked hypophosphatemic mouse. J Clin Invest 71: 400-403, 1983.
    • (1983) J Clin Invest , vol.71 , pp. 400-403
    • Lobaugh, B.1    Drezner, M.K.2
  • 32
  • 33
    • 18144423534 scopus 로고    scopus 로고
    • Structural basis for fibroblast growth factor receptor activation
    • Mohammadi M, Olsen SK, Ibrahimi OA. Structural basis for fibroblast growth factor receptor activation. Cytokine Growth Factor Rev 16: 107-137, 2005.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 107-137
    • Mohammadi, M.1    Olsen, S.K.2    Ibrahimi, O.A.3
  • 34
    • 0033951768 scopus 로고    scopus 로고
    • FGFs, heparan sulfate and FGFRs: Complex interactions essential for development
    • Ornitz DM. FGFs, heparan sulfate and FGFRs: complex interactions essential for development. Bioessays 22: 108-112, 2000.
    • (2000) Bioessays , vol.22 , pp. 108-112
    • Ornitz, D.M.1
  • 36
    • 0018094534 scopus 로고
    • Hereditary hypophosphataemic rickets with autosomal recessive inheritance and severe osteosclerosis. A report of two cases
    • Perry W, Stamp TC. Hereditary hypophosphataemic rickets with autosomal recessive inheritance and severe osteosclerosis. A report of two cases. J Bone Joint Surg Br 60-B: 430-434, 1978.
    • (1978) J Bone Joint Surg Br , vol.60 , Issue.B , pp. 430-434
    • Perry, W.1    Stamp, T.C.2
  • 37
    • 36049037977 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1a-hydroxylase expression in vitro
    • Perwad F, Zhang MY, Tenenhouse HS, Portale AA. Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1a-hydroxylase expression in vitro. Am J Physiol Renal Physiol 293: F1577-F1583, 2007.
    • (2007) Am J Physiol Renal Physiol , vol.293
    • Perwad, F.1    Zhang, M.Y.2    Tenenhouse, H.S.3    Portale, A.A.4
  • 38
    • 33644990455 scopus 로고    scopus 로고
    • Role of fibroblast growth factor receptors 1 and 2 in the metanephric mesenchyme
    • Poladia DP, Kish K, Kutay B, Hains D, Kegg H, Zhao H, Bates CM. Role of fibroblast growth factor receptors 1 and 2 in the metanephric mesenchyme. Dev Biol 291: 325-339, 2006.
    • (2006) Dev Biol , vol.291 , pp. 325-339
    • Poladia, D.P.1    Kish, K.2    Kutay, B.3    Hains, D.4    Kegg, H.5    Zhao, H.6    Bates, C.M.7
  • 39
  • 40
    • 0031030910 scopus 로고    scopus 로고
    • Effect of glucocorticoids on neonatal rabbit renal cortical sodium-inorganic phosphate messenger RNA and protein abundance
    • Prabhu S, Levi M, Dwarakanath V, Arar M, Biber J, Murer H, Baum M. Effect of glucocorticoids on neonatal rabbit renal cortical sodium-inorganic phosphate messenger RNA and protein abundance. Pediatr Res 41: 20-24, 1997.
    • (1997) Pediatr Res , vol.41 , pp. 20-24
    • Prabhu, S.1    Levi, M.2    Dwarakanath, V.3    Arar, M.4    Biber, J.5    Murer, H.6    Baum, M.7
  • 41
    • 79960636583 scopus 로고    scopus 로고
    • Fibroblast growth fac-tor-23 regulates renal 1,25(OH)(2) D and phosphate metabolism via the MAP kinase signaling pathway in Hyp mice
    • In press
    • Ranch D, Zhang MY, Portale AA, Perwad F. Fibroblast growth fac-tor-23 regulates renal 1,25(OH)(2) D and phosphate metabolism via the MAP kinase signaling pathway in Hyp mice. J Bone Miner Res In press.
    • J Bone Miner Res
    • Ranch, D.1    Zhang, M.Y.2    Portale, A.A.3    Perwad, F.4
  • 44
    • 9644303231 scopus 로고    scopus 로고
    • Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice
    • Sitara D, Razzaque MS, Hesse M, Yoganathan S, Taguchi T, Erben RG, Juppner H, Lanske B. Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice. Matrix Biol 23: 421-432, 2004.
    • (2004) Matrix Biol , vol.23 , pp. 421-432
    • Sitara, D.1    Razzaque, M.S.2    Hesse, M.3    Yoganathan, S.4    Taguchi, T.5    Erben, R.G.6    Juppner, H.7    Lanske, B.8
  • 45
    • 34247545717 scopus 로고    scopus 로고
    • Genetic ablation of vitamin D activation pathway reverses biochemical and skeletal anomalies in Fgf-23-null animals
    • Sitara D, Razzaque MS, St-Arnaud R, Huang W, Taguchi T, Erben RG, Lanske B. Genetic ablation of vitamin D activation pathway reverses biochemical and skeletal anomalies in Fgf-23-null animals. Am J Pathol 169: 2161-2170, 2006.
    • (2006) Am J Pathol , vol.169 , pp. 2161-2170
    • Sitara, D.1    Razzaque, M.S.2    St-Arnaud, R.3    Huang, W.4    Taguchi, T.5    Erben, R.G.6    Lanske, B.7
  • 46
    • 0017716263 scopus 로고
    • Phosphate transport in the proximal convolution of the rat kidney. I. Tubular heterogeneity, effect of parathyroid hormone in acute and chronic parathyroidectomized animals and effect of phosphate diet
    • Ullrich KJ, Rumrich G, Kloss S. Phosphate transport in the proximal convolution of the rat kidney. I. Tubular heterogeneity, effect of parathyroid hormone in acute and chronic parathyroidectomized animals and effect of phosphate diet. Pflügers Arch 372: 269-274, 1977.
    • (1977) Pflügers Arch , vol.372 , pp. 269-274
    • Ullrich, K.J.1    Rumrich, G.2    Kloss, S.3
  • 49
    • 0031700905 scopus 로고    scopus 로고
    • FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung
    • Weinstein M, Xu X, Ohyama K, Deng CX. FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development 125: 3615-3623, 1998.
    • (1998) Development , vol.125 , pp. 3615-3623
    • Weinstein, M.1    Xu, X.2    Ohyama, K.3    Deng, C.X.4
  • 51
    • 33744937606 scopus 로고    scopus 로고
    • Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family
    • Zhang X, Ibrahimi OA, Olsen SK, Umemori H, Mohammadi M, Ornitz DM. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem 281: 15694-15700, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 15694-15700
    • Zhang, X.1    Ibrahimi, O.A.2    Olsen, S.K.3    Umemori, H.4    Mohammadi, M.5    Ornitz, D.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.