Qualitative and quantitative studies on impurities in G004, a potential hypoglycaemic agent, using liquid chromatography, nuclear magnetic resonance and mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 56, Issue 3, 2011, Pages 627-632

  Liu, Wenyuan ^a   Zhou, Ainan ^a   Feng, Feng ^a   Zhang, Huibin ^a   Zhou, Jinpei ^a   Huang, Wenlong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

1 (4 (2 (2 Bromobenzenesulphonamino) ethyl) phenylsuphonyl) 3 (trans 4 methylcyclohexyl) urea; 1 (4 (2 (4 Bromobenzenesulphonamino) ethyl) phenylsuphonyl) 3 (trans 4 methylcyclohexyl) urea; G004 impurities; LC MS; NMR spectroscopy

Indexed keywords

1 [4 [2 (4 BROMOBENZENESULPHONAMINO)ETHYL]PHENYLSUPHONYL] 3 (4 METHYLCYCLOHEXYL)UREA; ANTIDIABETIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; DRUG IMPURITY; DRUG ISOLATION; DRUG STRUCTURE; LABORATORY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUALITATIVE ANALYSIS; QUALITY CONTROL; VALIDATION STUDY;

CHROMATOGRAPHY, REVERSE-PHASE; DRUG CONTAMINATION; HYPOGLYCEMIC AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SULFHYDRYL COMPOUNDS; UREA;

EID: 79961126684     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.06.017     Document Type: Article

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