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Volumn 12, Issue 7, 2011, Pages 647-651

The risk of adverse drug reactions in older patients: Beyond drug metabolism

Author keywords

Adverse drug reactions; Cognitive impairment; Comorbidity; Disability; Geriatric evaluation and management; Older adults

Indexed keywords

CHRONIC DISEASE; COGNITIVE DEFECT; COMORBIDITY; DISABILITY; DRUG EFFICACY; DRUG METABOLISM; ELDERLY CARE; GERIATRIC DISORDER; IATROGENIC DISEASE; LIFE EXPECTANCY; PRESCRIPTION; REVIEW;

EID: 79961095535     PISSN: 13892002     EISSN: 18755453     Source Type: Journal    
DOI: 10.2174/138920011796504563     Document Type: Review
Times cited : (41)

References (53)
  • 1
    • 0036904903 scopus 로고    scopus 로고
    • Adverse drug reactions as cause of hospital admissions: Results from the Italian group of pharmacoepidemiology in the elderly (GIFA)
    • DOI 10.1046/j.1532-5415.2002.50607.x
    • Onder, G.; Pedone, C.; Landi, F.; Cesari, M.; Della Vedova, C.; Bernabei, R.; Gambassi, G. Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA). J. Am. Geriatr. Soc., 2002, 50, 1962-1968. (Pubitemid 35462441)
    • (2002) Journal of the American Geriatrics Society , vol.50 , Issue.12 , pp. 1962-1968
    • Onder, G.1    Pedone, C.2    Landi, F.3    Cesari, M.4    Della Vedova, C.5    Bernabei, R.6    Gambassi, G.7
  • 4
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: A meta- analysis of prospective studies
    • DOI 10.1001/jama.279.15.1200
    • Lazarou, J.; Pomeranz, B.H.; Corey, P.N. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA, 1998, 279, 1200-1205. (Pubitemid 28193431)
    • (1998) Journal of the American Medical Association , vol.279 , Issue.15 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 5
    • 70149103802 scopus 로고    scopus 로고
    • Pharmacokinetics and drug metabolism in the elderly
    • Klotz, U. Pharmacokinetics and drug metabolism in the elderly. Drug Metab. Rev., 2009, 41, 67-76.
    • (2009) Drug Metab. Rev. , vol.41 , pp. 67-76
    • Klotz, U.1
  • 7
    • 77954635386 scopus 로고    scopus 로고
    • Development of CRIteria to assess appropriate Medication use among Elderly complex patients (CRIME) project: Rationale and methodology
    • Fusco, D.; Lattanzio, F.; Tosato, M.; Corsonello, A.; Cherubini, A.; Volpato, S.; Maraldi, C.; Ruggiero, C.; Onder, G. Development of CRIteria to assess appropriate Medication use among Elderly complex patients (CRIME) project: rationale and methodology. Drugs Aging, 2009, 26 Suppl 1, 3-13.
    • (2009) Drugs Aging , vol.26 SUPPL. 1 , pp. 3-13
    • Fusco, D.1    Lattanzio, F.2    Tosato, M.3    Corsonello, A.4    Cherubini, A.5    Volpato, S.6    Maraldi, C.7    Ruggiero, C.8    Onder, G.9
  • 8
    • 34247578803 scopus 로고    scopus 로고
    • Geriatric syndromes: Clinical, research, and policy implications of a core geriatric concept
    • DOI 10.1111/j.1532-5415.2007.01156.x
    • Inouye, S.K.; Studenski, S.; Tinetti, M.; Kuchel, G.A. Geriatric Syndromes: Clinical, Research, and Policy Implications of a Core Geriatric Concept. J. Am. Geriatr. Soc., 2007, 55, 780-791. (Pubitemid 46668974)
    • (2007) Journal of the American Geriatrics Society , vol.55 , Issue.5 , pp. 780-791
    • Inouye, S.K.1    Studenski, S.2    Tinetti, M.E.3    Kuchel, G.A.4
  • 9
    • 61449244694 scopus 로고    scopus 로고
    • The co-occurrence of chronic diseases and geriatric syndromes: The health and retirement study
    • Lee, P.G.; Cigolle, C.; Blaum, C. The Co-Occurrence of Chronic Diseases and Geriatric Syndromes: The Health and Retirement Study. J. Am. Geriatr. Soc., 2009, 57, 511-516.
    • (2009) J. Am. Geriatr. Soc. , vol.57 , pp. 511-516
    • Lee, P.G.1    Cigolle, C.2    Blaum, C.3
  • 10
    • 0032896456 scopus 로고    scopus 로고
    • Association of comorbidity with disability in older women: The Women's Health and Aging Study
    • DOI 10.1016/S0895-4356(98)00124-3
    • Fried, L.P.; Bandeen-Roche, K.; Kasper, J.D.; Guralnik, J.M. Association of comorbidity with disability in older women: the Women's Health and Aging Study. J. Clin. Epidemiol., 1999, 52, 27-37. (Pubitemid 29064271)
    • (1999) Journal of Clinical Epidemiology , vol.52 , Issue.1 , pp. 27-37
    • Fried, L.P.1    Bandeen-Roche, K.2    Kasper, J.D.3    Guralnik, J.M.4
  • 11
    • 31544460681 scopus 로고    scopus 로고
    • Comorbidity and physical function: Results from the aging and longevity study in the sirente geographic area (iISIRENTE Study)
    • DOI 10.1159/000089822
    • Cesari, M.; Onder, G.; Russo, A.; Zamboni, V.; Barillaro, C.; Ferrucci, L.; Pahor, M.; Bernabei, R.; Landi, F. Comorbidity and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study). Gerontology, 2006, 52, 24-32. (Pubitemid 43162717)
    • (2006) Gerontology , vol.52 , Issue.1 , pp. 24-32
    • Cesari, M.1    Onder, G.2    Russo, A.3    Zamboni, V.4    Barillaro, C.5    Ferrucci, L.6    Pahor, M.7    Bernabei, R.8    Landi, F.9
  • 17
    • 61849178843 scopus 로고    scopus 로고
    • Comorbidity and repeat admission to hospital for adverse drug reactions in older adults: Retrospective cohort study
    • Jan 7
    • Zhang, M.; Holman, C.D.; Price, S.D.; Sanfilippo, F.M.; Preen, D.B.; Bulsara, M.K. Comorbidity and repeat admission to hospital for adverse drug reactions in older adults: retrospective cohort study. BMJ, 2009 Jan 7, 338, a2752.
    • (2009) BMJ , vol.338
    • Zhang, M.1    Holman, C.D.2    Price, S.D.3    Sanfilippo, F.M.4    Preen, D.B.5    Bulsara, M.K.6
  • 18
    • 34447261692 scopus 로고    scopus 로고
    • The challenge of managing drug interactions in elderly people
    • DOI 10.1016/S0140-6736(07)61092-7, PII S0140673607610927
    • Mallet, L.; Spinewine, A.; Huang, A. The challenge of managing drug interactions in elderly people. Lancet, 2007, 370, 185-191. (Pubitemid 47042897)
    • (2007) Lancet , vol.370 , Issue.9582 , pp. 185-191
    • Mallet, L.1    Spinewine, A.2    Huang, A.3
  • 19
    • 0036231685 scopus 로고    scopus 로고
    • The aging liver: Structural and functional changes and their consequences for drug treatment in old age
    • DOI 10.1159/000052829
    • Zeeh, J.; Platt, D. The aging liver: structural and functional changes and their consequences for drug treatment in old age. Gerontology, 2002, 48, 121-127. (Pubitemid 34310065)
    • (2002) Gerontology , vol.48 , Issue.3 , pp. 121-127
    • Zeeh, J.1    Platt, D.2
  • 20
    • 70349092256 scopus 로고    scopus 로고
    • Adverse drug reactions and impaired renal function in elderly patients admitted to the emergency department: A retrospective study
    • Helldén, A.; Bergman, U.; von Euler, M.; Hentschke, M.; Odar- Cederlöf, I.; Ohlén, G. Adverse drug reactions and impaired renal function in elderly patients admitted to the emergency department: a retrospective study. Drugs Aging, 2009, 26, 595-606.
    • (2009) Drugs Aging , vol.26 , pp. 595-606
    • Helldén, A.1    Bergman, U.2    Von Euler, M.3    Hentschke, M.4    Odar-Cederlöf, I.5    Ohlén, G.6
  • 21
    • 17644380282 scopus 로고    scopus 로고
    • Concealed renal insufficiency and adverse drug reactions in elderly hospitalized patients
    • DOI 10.1001/archinte.165.7.790
    • Corsonello, A.; Pedone, C.; Corica, F.; Mussi, C.; Carbonin, P.; Antonelli Incalzi, R. Gruppo Italiano di Farmacovigilanza nell'Anziano (GIFA) Investigators.Concealed renal insufficiency and adverse drug reactions in elderly hospitalized patients. Arch. Intern. Med., 2005, 165, 790-795. (Pubitemid 40569433)
    • (2005) Archives of Internal Medicine , vol.165 , Issue.7 , pp. 790-795
    • Corsonello, A.1    Pedone, C.2    Corica, F.3    Mussi, C.4    Carbonin, P.5    Incalzi, R.A.6
  • 23
    • 0023765108 scopus 로고
    • Clinical pharmacokinetics in heart failure. An updated review
    • Shammas, F.V.; Dickstein, K. Clinical pharmacokinetics in heart failure. An updated review. Clin. Pharmacokinet., 1988, 15, 94-113.
    • (1988) Clin. Pharmacokinet. , vol.15 , pp. 94-113
    • Shammas, F.V.1    Dickstein, K.2
  • 24
    • 41549153249 scopus 로고    scopus 로고
    • Modulation of cardiac and hepatic cytochrome P450 enzymes during heart failure
    • DOI 10.2174/138920008783571792
    • Zordoky, B.N.; El-Kadi, A.O. Modulation of cardiac and hepatic cytochrome P450 enzymes during heart failure. Curr. Drug Metab., 2008, 9, 122-128. (Pubitemid 351461001)
    • (2008) Current Drug Metabolism , vol.9 , Issue.2 , pp. 122-128
    • Zordoky, B.N.M.1    El-Kadi, A.O.S.2
  • 25
    • 0037429120 scopus 로고    scopus 로고
    • Investigators of the Gruppo Italiano di Farmacoepidemiologia nell'Anziano Study. Depression and adverse drug reactions among hospitalized older adults
    • Onder, G.; Penninx, B.W.; Landi, F.; Atkinson, H.; Cesari, M.; Bernabei, R.; Pahor, M.; Investigators of the Gruppo Italiano di Farmacoepidemiologia nell'Anziano Study. Depression and adverse drug reactions among hospitalized older adults. Arch. Intern. Med., 2003, 163, 301-305.
    • (2003) Arch. Intern. Med. , vol.163 , pp. 301-305
    • Onder, G.1    Penninx, B.W.2    Landi, F.3    Atkinson, H.4    Cesari, M.5    Bernabei, R.6    Pahor, M.7
  • 28
    • 0028887604 scopus 로고
    • Psychoneuroimmunology: Interactions between the nervous system and the immune system
    • Ader, R.; Cohen, N.; Felten, D. Psychoneuroimmunology: interactions between the nervous system and the immune system. Lancet, 1995, 345,99-103.
    • (1995) Lancet , vol.345 , pp. 99-103
    • Ader, R.1    Cohen, N.2    Felten, D.3
  • 29
    • 19544361856 scopus 로고    scopus 로고
    • Incidence of intracranial hemorrhage in patients with atrial fibrillation who are prone to fall
    • DOI 10.1016/j.amjmed.2005.02.022, PII S0002934305001415
    • Gage, B.F.; Birman-Deych, E.; Kerzner, R.; Radford, M.J.; Nilasena, D.S.; Rich, M.W. Incidence of intracranial hemorrhage in patients with atrial fibrillation who are prone to fall. Am. J. Med., 2005, 118, 612-617. (Pubitemid 40732700)
    • (2005) American Journal of Medicine , vol.118 , Issue.6 , pp. 612-617
    • Gage, B.F.1    Birman-Deych, E.2    Kerzner, R.3    Radford, M.J.4    Nilasena, D.S.5    Rich, M.W.6
  • 30
    • 73949091431 scopus 로고    scopus 로고
    • Orthostatic hypotension predicts all-cause mortality and coronary events in middle-aged individuals (The Malmo Preventive Project)
    • Fedorowski, A.; Stavenow, L.; Hedblad, B.; Berglund, G.; Nilsson, PM.; Melander, O. Orthostatic hypotension predicts all-cause mortality and coronary events in middle-aged individuals (The Malmo Preventive Project). Eur. Heart J., 2010, 31, 85-91
    • (2010) Eur. Heart J. , vol.31 , pp. 85-91
    • Fedorowski, A.1    Stavenow, L.2    Hedblad, B.3    Berglund, G.4    Nilsson, P.M.5    Melander, O.6
  • 31
    • 56649093028 scopus 로고    scopus 로고
    • Adherence to medication in patients with dementia: Predictors and strategies for improvement
    • Arlt, S.; Lindner, R.; Rösler, A.; von Renteln-Kruse, W. Adherence to medication in patients with dementia: predictors and strategies for improvement. Drugs Aging, 2008, 25, 1033-1047.
    • (2008) Drugs Aging , vol.25 , pp. 1033-1047
    • Arlt, S.1    Lindner, R.2    Rösler, A.3    Von Renteln-Kruse, W.4
  • 36
    • 57749191477 scopus 로고    scopus 로고
    • Rational prescribing for patients with a reduced life expectancy
    • Holmes, H.M. Rational Prescribing for Patients With a Reduced Life Expectancy. Clin. Pharmacol. Ther., 2009, 85, 103-107.
    • (2009) Clin. Pharmacol. Ther. , vol.85 , pp. 103-107
    • Holmes, H.M.1
  • 37
    • 36148992567 scopus 로고    scopus 로고
    • Appropriate application of evidence to the care of elderly patients with diabetes
    • Huang, E.S. Appropriate application of evidence to the care of elderly patients with diabetes. Curr. Diabetes Rev., 2007, 3, 260-263. (Pubitemid 350111109)
    • (2007) Current Diabetes Reviews , vol.3 , Issue.4 , pp. 260-263
    • Huang, E.S.1
  • 38
    • 35048887519 scopus 로고    scopus 로고
    • Individualising therapy for older adults with diabetes mellitus
    • Cayea, D.; Boyd, C.; Durso, S.C. Individualising therapy for older adults with diabetes mellitus. Drugs Aging, 2007, 24, 851-863. (Pubitemid 47553793)
    • (2007) Drugs and Aging , vol.24 , Issue.10 , pp. 851-863
    • Cayea, D.1    Boyd, C.2    Durso, S.C.3
  • 39
  • 40
    • 23344445915 scopus 로고    scopus 로고
    • Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: Implications for pay for performance
    • DOI 10.1001/jama.294.6.716
    • Boyd, C.M.; Darer, J.; Boult, C.; Fried, LP.; Boult, L.; Wu, AW. Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. JAMA, 2005, 294, 716-724. (Pubitemid 41159291)
    • (2005) Journal of the American Medical Association , vol.294 , Issue.6 , pp. 716-724
    • Boyd, C.M.1    Darer, J.2    Boult, C.3    Fried, L.P.4    Boult, L.5    Wu, A.W.6
  • 41
    • 19944412446 scopus 로고    scopus 로고
    • Potential pitfalls of disease-specific guidelines for patients with multiple conditions
    • Tinetti, M.E.; Bogardus, S.T. Jr.; Agostini, J.V. Potential pitfalls of disease-specific guidelines for patients with multiple conditions. N. Engl. J. Med., 2004, 351, 2870-2874.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 2870-2874
    • Tinetti, M.E.1    Bogardus Jr., S.T.2    Agostini, J.V.3
  • 42
    • 70349329580 scopus 로고    scopus 로고
    • Medication use and increased risk of falls in hospitalized elderly patients: A retrospective, case-control study
    • Rhalimi M, Helou R, Jaecker P. Medication use and increased risk of falls in hospitalized elderly patients: a retrospective, case-control study. Drugs Aging. 2009, 26, 847-852.
    • (2009) Drugs Aging. , vol.26 , pp. 847-852
    • Rhalimi, M.1    Helou, R.2    Jaecker, P.3
  • 46
    • 0030641191 scopus 로고    scopus 로고
    • Do we practice geriatric cardiology?
    • Parmley W.W, Do we practice geriatric cardiology? JACC 1997; 29: 217-218.
    • (1997) JACC , vol.29 , pp. 217-218
    • Parmley, W.W.1
  • 48
    • 67649510151 scopus 로고    scopus 로고
    • Medication errors in elderly people: Contributing factors and future perspectives
    • Fialová, D.; Onder, G. Medication errors in elderly people: contributing factors and future perspectives. Br. J. Clin. Pharmacol., 2009, 67, 641-645.
    • (2009) Br. J. Clin. Pharmacol. , vol.67 , pp. 641-645
    • Fialová, D.1    Onder, G.2
  • 49
    • 0025225326 scopus 로고
    • The Senior Care Study. The optimal use of medications in acutely ill older patients
    • Owens, N.J.; Sherburne, N.J.; Silliman, R.A.; Fretwell, M.D. The Senior Care Study. The optimal use of medications in acutely ill older patients. J. Am. Geriatr. Soc., 1990, 38, 1082-1087.
    • (1990) J. Am. Geriatr. Soc. , vol.38 , pp. 1082-1087
    • Owens, N.J.1    Sherburne, N.J.2    Silliman, R.A.3    Fretwell, M.D.4
  • 51
    • 8644285453 scopus 로고    scopus 로고
    • An outreach geriatric medication advisory service in residential aged care: A randomised controlled trial of case conferencing
    • DOI 10.1093/ageing/afh213
    • Crotty, M.; Halbert, J.; Rowett, D.; Giles, L.; Birks, R.; Williams, H.; Whitehead, C. An outreach geriatric medication advisory service in residential aged care: a randomised controlled trial of case conferencing. Age Ageing, 2004, 33, 612-617. (Pubitemid 39504296)
    • (2004) Age and Ageing , vol.33 , Issue.6 , pp. 612-617
    • Crotty, M.1    Halbert, J.2    Rowett, D.3    Giles, L.4    Birks, R.5    Williams, H.6    Whitehead, C.7
  • 52
    • 29144451844 scopus 로고    scopus 로고
    • Patterns of drug prescription in a geriatric evaluation and management unit as compared with the general medical wards: A randomised study
    • DOI 10.1007/s00228-005-0046-2
    • Saltvedt, I.; Spigset, O.; Ruths, S.; Fayers, P.; Kaasa, S.; Sletvold, O. Patterns of drug prescription in a geriatric evaluation and management unit as compared with the general medical wards: a randomized study. Eur. J. Clin. Pharmacol., 2005, 61, 921-928. (Pubitemid 41803703)
    • (2005) European Journal of Clinical Pharmacology , vol.61 , Issue.12 , pp. 921-928
    • Saltvedt, I.1    Spigset, O.2    Ruths, S.3    Fayers, P.4    Kaasa, S.5    Sletvold, O.6
  • 53
    • 77953256268 scopus 로고    scopus 로고
    • Effects of medication assessment as part of a comprehensive geriatric assessment on drug use over a 1-year period: A population- based intervention study
    • Lampela, P.; Hartikainen, S.; Lavikainen, P.; Sulkava, R.; Huupponen, R. Effects of medication assessment as part of a comprehensive geriatric assessment on drug use over a 1-year period: a population- based intervention study. Drugs Aging, 2010, 27, 507-521.
    • (2010) Drugs Aging , vol.27 , pp. 507-521
    • Lampela, P.1    Hartikainen, S.2    Lavikainen, P.3    Sulkava, R.4    Huupponen, R.5


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