First isolation and outbreak of OXA-48-producing Klebsiella pneumoniae in an Irish hospital, March to June 2011

Eurosurveillance

Volumn 16, Issue 29, 2011, Pages

  O'Brien, D J ^a   Wrenn, C ^a   Roche, C ^b   Rose, L ^b   Fenelon, C ^a   Flynn, A ^a   Murphy, V ^a   Fitzgerald, S F ^a   Fenelon, L E ^a   Crowley, B ^b   Schaffer, K ^a  

^a ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^b ST JAMES S HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AZTREONAM; CARBAPENEMASE; CARBAPENEMASE OXA 48; CEFEPIME; CEFOTAXIME; CEFTAZIDIME; CEFUROXIME; CIPROFLOXACIN; COLISTIN; ERTAPENEM; GENTAMICIN; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM; TIGECYCLINE; UNCLASSIFIED DRUG;

ANASTOMOSIS LEAKAGE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM CULTURE; BACTERIUM ISOLATION; BILIARY TRACT DRAINAGE; BLOODSTREAM INFECTION; CLINICAL ARTICLE; COLON RESECTION; DISINFECTION; DUODENUM ADENOCARCINOMA; DUODENUM CARCINOMA; ENZYME SYNTHESIS; EPIDEMIC; ESCHERICHIA COLI; FEMALE; HOSPITAL PATIENT; HUMAN; INFECTION CONTROL; IRELAND; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; MALE; PANCREATICODUODENECTOMY; PATIENT CARE; TERTIARY HEALTH CARE;

EID: 79961069539     PISSN: 1025496X     EISSN: 15607917     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Carrër A, Poirel L, Eraksoy H, Cagatay AA, Badur S, Nordmann P. Spread of OXA-48-positive-carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul,Turkey. Antimicrob Agents Chemother. 2008;52(8):2950-4.
2. Carrër A, Poirel L, Yilmaz M, Akan OA, Feriha C, Cuzon G, et al. Spread of OXA-48 encoding plasmid in Turkey and beyond. Antimicrob Agents Chemother. 2010;54(3):1369-73.
3. Cuzon G, Naas T, Lesenne A, Benhamou M, Nordmann P. Plasmid-mediated carbapenem-hydrolysing OXA-48 betalactamase in Klebsiella pneumoniae from Tunisia. Int J Antimicrob Agents. 2010;36(1):91-3.
4. Benouda A, Touzani O, Khairallah MT, Araj GF, Matar GM. First detection of an oxacillinase-mediated resistance to carbapenem in Klebsiella pneumonia from Morrocco. Ann Trop Med Parasitol. 2010;104(4):327-30.
5. Grundmann H, Livermore DM, Giske CG, Canton R, Rossolini GM, Campos J, et al. Carbapenem-non-susceptible Enterobacteriaceae in Europe: conclusions from a meeting of national experts. Euro Surveill. 2010;15(46):pii=19711. Available from: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19711
6. European Committee on Antimicrobial Susceptibility Testing. Breakpoint tables for interpretation of MICs and zone diameters. Version 1.3, January 5, 2011. Available from: http://www.eucast.org/fileadmin/src/media/PDFs/EUCAST_files/Disk_test_documents/EUCAST_breakpoints_v1.3_pdf.pdf
7. Prior AR, Roche C, Lynch M, Kelly S, O'Rourke K, Crowley B. First identified case of VIM-producing carbapenem-resistant Klebsiella pneumoniae in the Republic of Ireland associated with fatal outcome. Euro Surveill. 2010;15(50):pii=19752. Available from: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19752
8. Roche C, Cotter M, O'Connell N, Crowley B. First identification of Class A carbapenemase-producing Klebsiella pneumoniae in the Republic of Ireland. Eurosurveill. 2009;14(13):pii=19163. Available from: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19163
9. Kaczmarek FM, Dib-Hajj F, Shang W, Gootz TD. High-level carbapenem resistance in a Klebsiella pneumoniae clinical isolate is due to the combination of bla(ACT-1) beta-lactamase production, porin OmpK35/36 insertional inactivation, and down-regulation of the phosphate transport porin phoe. Antimicrob Agents Chemother. 2006;50(10):3396-406.
10. Centers for Disease Control and Prevention (CDC). Guidance for control of infections with carbapenem-resistant or carbapenemase-producing Enterobacteriaceae in acute care facilities. MMWR Morb Mortal Wkly Rep. 2009; 58(10):256-60.