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Volumn 119, Issue 8, 2011, Pages 1047-1052

Current assessment of the effects of environmental chemicals on the mammary gland in guideline rodent studies by the U.S. environmental protection agency (U.S. EPA), organisation for economic co-operation and development (OECD), and national toxicology program (NTP)

Author keywords

Carcinogenicity study; Endocrine disrupting chemicals; Extended one generation reproduction study; Mammary gland; Perinatal exposure; Risk assessment; Subchronic toxicity study; Toxicity testing guidelines; Two generation reproduction study

Indexed keywords

ENDOCRINE DISRUPTOR; ENVIRONMENTAL CHEMICAL;

EID: 79961064526     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1002676     Document Type: Article
Times cited : (25)

References (51)
  • 1
    • 0030887391 scopus 로고    scopus 로고
    • Reproductive assessment by continuous breeding: Evolving study design and summaries of ninety studies
    • Chapin RE, Sloane RA. 1996. Reproductive assessment by continuous breeding: evolving study design and summaries of ninety studies. Environ Health Perspect 105(suppl 1):199-205.
    • (1996) Environ Health Perspect , vol.105 , Issue.SUPPL. 1 , pp. 199-205
    • Chapin, R.E.1    Sloane, R.A.2
  • 2
    • 84856312356 scopus 로고    scopus 로고
    • NTP (National Toxicology Program), Available, [accessed 15 June 2011]
    • NTP (National Toxicology Program). 2008. Descriptions of NTP Study Types. Available: http://ehsntpwp03.niehs.nih.gov/INDEXD65D.HTM?objectid=72015D9F-BDB7-CEBAF4EB4F9BF507820C [accessed 15 June 2011].
    • (2008) Descriptions of NTP Study Types
  • 3
    • 84856311961 scopus 로고    scopus 로고
    • NTP (National Toxicology Program), Available, accessed 15 June 2011
    • NTP (National Toxicology Program). 2010a. Descriptions of NTP Study Types: Perinatal Exposure. Available: http://ehsntpwp03.niehs.nih.gov/INDEX3F6A.HTM?objectid=6B4371F1-F1F6-975E-798578C7A860D385 [accessed 15 June 2011].
    • (2010) Descriptions of NTP Study Types: Perinatal Exposure
  • 4
    • 84856311780 scopus 로고    scopus 로고
    • NTP (National Toxicology Program), Available, accssed 15 June 2011
    • NTP (National Toxicology Program). 2010b. Descriptions of NTP Study Types: Toxicology/Carcinogenicity. Available: http://ehsntpwp03.niehs.nih.gov/INDEX33B7.HTM?objectid=72015DAF-BDB7-CEBA-F9A7F9CAA57DD7F5 [accssed 15 June 2011].
    • (2010) Descriptions of NTP Study Types: Toxicology/Carcinogenicity
  • 5
    • 84856308440 scopus 로고
    • OECD Guidelines for Chemical Testing
    • OECD (Organisation for Economic Co-operation and Development), TG 410. Paris:OECD. Available, [accessed 14 June 2011
    • OECD (Organisation for Economic Co-operation and Development). 1981a. OECD Guidelines for Chemical Testing. Repeated Dose Dermal Toxicity: 21/28-Day Study. TG 410. Paris:OECD. Available: http://www.oecd-ilibrary.org/environment/test-no-410-repeated-dose-dermal-toxicity-21-28-day-study_9789264070745-en [accessed 14 June 2011].
    • (1981) Repeated Dose Dermal Toxicity: 21/28-Day Study
  • 6
    • 84856314522 scopus 로고
    • OECD Guidelines for Chemical Testing
    • OECD (Organisation for Economic Co-operation and Development), TG 411. Paris:OECD. Available:, accessed 14 June 2011
    • OECD (Organisation for Economic Co-operation and Development). 1981b. OECD Guidelines for Chemical Testing. Repeated Dose Dermal Toxicity: 90-Day Study. TG 411. Paris:OECD. Available: http://www.oecd-ilibrary.org/environment/test-no-411-subchronic-dermal-toxicity-90-day-study_9789264070769-en [accessed 14 June 2011].
    • (1981) Repeated Dose Dermal Toxicity: 90-Day Study
  • 7
    • 67650787475 scopus 로고    scopus 로고
    • OECD Guideline for Testing of Chemicals
    • OECD (Organisation for Economic Co-operation and Development), TG 415. Paris:OECD
    • OECD (Organisation for Economic Co-operation and Development). 1983. OECD Guideline for Testing of Chemicals. One-Generation Reproduction Toxicity Study. TG 415. Paris:OECD.
    • (1983) One-Generation Reproduction Toxicity Study
  • 8
    • 79961036908 scopus 로고
    • OECD Guideline for Testing of Chemicals
    • OECD (Organisation for Economic Co-operation and Development)., TG 421. Paris:OECD
    • OECD (Organisation for Economic Co-operation and Development). 1995. OECD Guideline for Testing of Chemicals. Reproduction/Developmental Toxicity Screening Test. TG 421. Paris:OECD.
    • (1995) Reproduction/Developmental Toxicity Screening Test
  • 10
    • 0003521882 scopus 로고    scopus 로고
    • OECD Guideline for the Testing of Chemicals
    • OECD (Organisation for Economic Co-operation and Development), TG 408. Paris:OECD
    • OECD (Organisation for Economic Co-operation and Development). 1998a. OECD Guideline for the Testing of Chemicals. Repeated Dose 90-Day Oral Toxicity Study in Rodents. TG 408. Paris:OECD.
    • (1998) Repeated Dose 90-Day Oral Toxicity Study In Rodents
  • 11
    • 84856312007 scopus 로고    scopus 로고
    • OECD Guidelines for Chemical Testing
    • OECD (Organisation for Economic Co-operation and Development), TG 409. Available, [accessed 14 June 2011]
    • OECD (Organisation for Economic Co-operation and Development). 1998b. OECD Guidelines for Chemical Testing. Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents. TG 409. Available: http://www.oecd-ilibrary.org/environment/test-no-409-repeated-dose-90-dayoral-toxicity-study-in-non-rodents_9789264070721-en [accessed 14 June 2011].
    • (1998) Repeated Dose 90-Day Oral Toxicity Study In Non-Rodents
  • 12
    • 84856312133 scopus 로고    scopus 로고
    • OECD Guidelines for Chemical Testing
    • OECD (Organisation for Economic Co-operation and Development)., TG 414. Paris:OECD. Available, [accessed 14 June 2011]
    • OECD (Organisation for Economic Co-operation and Development). 2001a. OECD Guidelines for Chemical Testing. Prenatal Developmental Toxicity Study. TG 414. Paris:OECD. Available: http://www.oecd-ilibrary.org/environment/test-no-414-prenatal-development-toxicity-study_9789264070820-en [accessed 14 June 2011].
    • (2001) Prenatal Developmental Toxicity Study
  • 13
    • 67650787475 scopus 로고    scopus 로고
    • OECD Guideline for Testing of Chemicals
    • OECD (Organisation for Economic Co-operation and Development), TG 416. Paris:OECD
    • OECD (Organisation for Economic Co-operation and Development). 2001b. OECD Guideline for Testing of Chemicals. Two-Generation Reproduction Toxicity Study. TG 416. Paris:OECD.
    • (2001) Two-Generation Reproduction Toxicity Study
  • 14
    • 35648982178 scopus 로고    scopus 로고
    • OECD Guideline for Testing of Chemicals
    • OECD (Organisation for Economic Co-operation and Development), TG 407. Paris:OECD
    • OECD (Organisation for Economic Co-operation and Development). 2005. OECD Guideline for Testing of Chemicals. Repeated Dose 28-Day Oral Toxicity Study in Rodents. TG 407. Paris:OECD.
    • (2005) Repeated Dose 28-Day Oral Toxicity Study In Rodents
  • 15
    • 0003479926 scopus 로고    scopus 로고
    • OECD (Organisation for Economic Co-operation and Development)., Developmental Neurotoxicity Study. TG 426. Paris:OECD
    • OECD (Organisation for Economic Co-operation and Development). 2007a. OECD Guideline for Testing of Chemicals. Developmental Neurotoxicity Study. TG 426. Paris:OECD.
    • (2007) OECD Guideline For Testing of Chemicals
  • 16
    • 79961065446 scopus 로고    scopus 로고
    • OECD Guideline for Testing of Chemicals
    • OECD (Organisation for Economic Co-operation and Development)., TG 440. Paris:OECD
    • OECD (Organisation for Economic Co-operation and Development). 2007b. OECD Guideline for Testing of Chemicals. Uterotrophic Bioasay in Rodents: A Short-Term Screening Test for Oestrogenic Properties. TG 440. Paris:OECD.
    • (2007) Uterotrophic Bioasay In Rodents: A Short-Term Screening Test For Oestrogenic Properties
  • 17
    • 84856313587 scopus 로고    scopus 로고
    • OECD (Organisation for Economic Co-operation and Development), OECD Series on Testing and Assessment, No. 43: ENV/JM/MONO(2008)16. Paris:OECD. Available, accessed 24 November 2010]
    • OECD (Organisation for Economic Co-operation and Development). 2008. Guidance Document on Mammalian Reproductive Toxicity Testing and Assessment. OECD Series on Testing and Assessment, No. 43: ENV/JM/MONO(2008)16. Paris:OECD. Available: http://www.oecd.org/officialdocuments/displaydocumentpdf/?cote=ENV/JM/MONO(2008)16&doclanguage=en [accessed 24 November 2010].
    • (2008) Guidance Document On Mammalian Reproductive Toxicity Testing and Assessment
  • 18
    • 84856307529 scopus 로고    scopus 로고
    • OECD Guidelines for Chemical Testing
    • OECD (Organisation for Economic Co-operation and Development), TG 412. Paris:OECD. Available, accessed 14 June 2011
    • OECD (Organisation for Economic Co-operation and Development). 2009a. OECD Guidelines for Chemical Testing. Subacute Inhalation Toxicity: 28-Day Study. TG 412. Paris:OECD. Available: http://www.oecd-ilibrary.org/environment/test-no-412-subacute-inhalation-toxicity-28-day-study_9789264070783-en [accessed 14 June 2011].
    • (2009) Subacute Inhalation Toxicity: 28-Day Study
  • 19
    • 84856312611 scopus 로고    scopus 로고
    • OECD Guidelines for Chemical Testing
    • OECD (Organisation for Economic Co-operation and Development), TG 413. Paris:OECD. Available, accessed 14 June 2011
    • OECD (Organisation for Economic Co-operation and Development). 2009b. OECD Guidelines for Chemical Testing. Subchronic Inhalation Toxicity: 90-day Study. TG 413. Paris:OECD. Available: http://www.oecd-ilibrary.org/environment/test-no-413-subchronic-inhalation-toxicity-90-day-study_9789264070806-en [accessed 14 June 2011].
    • (2009) Subchronic Inhalation Toxicity: 90-day Study
  • 20
    • 79961050339 scopus 로고    scopus 로고
    • OECD Guideline for Testing of Chemicals
    • OECD (Organisation for Economic Co-operation and Development)., TG 441. Paris: OECD
    • OECD (Organisation for Economic Co-operation and Development). 2009c. OECD Guideline for Testing of Chemicals. Hershberger Bioassay in Rats: A Short-term Screening Assay for (Anti)Androgenic Properties. TG 441. Paris:OECD.
    • (2009) Hershberger Bioassay In Rats: A Short-term Screening Assay For (Anti)Androgenic Properties
  • 21
    • 84856313139 scopus 로고    scopus 로고
    • OECD Guidelines for Chemical Testing
    • OECD (Organisation for Economic Co-operation and Development)., TG 451. Paris:OECD. Available:, accessed 14 June 2011
    • OECD (Organisation for Economic Co-operation and Development). 2009d. OECD Guidelines for Chemical Testing. Carcinogenicity Studies. TG 451. Paris:OECD. Available: http://www.oecd-ilibrary.org/environment/test-no-451-carcinogenicity-studies_9789264071186-en [accessed 14 June 2011].
    • (2009) Carcinogenicity Studies
  • 22
    • 79961058784 scopus 로고    scopus 로고
    • OECD Guideline for the Testing of Chemicals
    • OECD (Organisation for Economic Co-operation and Development)., TG 452. Paris:OECD
    • OECD (Organisation for Economic Co-operation and Development). 2009e. OECD Guideline for the Testing of Chemicals. Chronic Toxicity Studies. TG 452. Paris: OECD.
    • (2009) Chronic Toxicity Studies
  • 23
    • 84926406007 scopus 로고    scopus 로고
    • OECD Guideline for the Testing of Chemicals
    • OECD (Organisation for Economic Co-operation and Development), TG 453. Paris: OECD
    • OECD (Organisation for Economic Co-operation and Development). 2009f. OECD Guideline for the Testing of Chemicals. Combined Chronic Toxicity/Carcinogenicity Studies. TG 453. Paris:OECD.
    • (2009) Combined Chronic Toxicity/Carcinogenicity Studie
  • 24
    • 84856312865 scopus 로고    scopus 로고
    • OECD Guideline for the Testing of Chemicals
    • OECD (Organisation for Economic Co-operation and Development), Paris: OECD. Available, [accessed 15 June 2011]
    • OECD (Organisation for Economic Co-operation and Development). 2010. OECD Guideline for the Testing of Chemicals. Draft Proposal for an Extended One-Generation Reproductiive Toxicity Study. Paris:OECD. Available: http://www.oecd.org/dataoecd/23/10/46466062.pdf [accessed 15 June 2011].
    • (2010) Draft Proposal For An Extended One-Generation Reproductiive Toxicity Study
  • 25
    • 0003479926 scopus 로고    scopus 로고
    • OECD (Organisation for Economic Co-operation and Development), Section 4: Health Effects. Available, [accessed 15 June 2011]
    • OECD (Organisation for Economic Co-operation and Development). 2011. OECD Guidelines for the Testing of Chemicals, Section 4: Health Effects. Available: http://www.oecd-ilibrary.org/environment/oecd-guidelines-for-thetesting-of-chemicals-section-4-health-effects_20745788;jsessionid=16wmoos6mokod.delta [accessed 15 June 2011].
    • (2011) OECD Guidelines for the Testing of Chemicals
  • 26
    • 79961059232 scopus 로고    scopus 로고
    • Environmental exposures and mammary gland development: State of the science, public health implications, and research recommendations
    • Rudel RA, Fenton SE, Ackerman JM, Euling SY, Makris SL. 2011. Environmental exposures and mammary gland development: state of the science, public health implications, and research recommendations. Environ Health Perspect 119:1053-1061.
    • (2011) Environ Health Perspect , vol.119 , pp. 1053-1061
    • Rudel, R.A.1    Fenton, S.E.2    Ackerman, J.M.3    Euling, S.Y.4    Makris, S.L.5
  • 27
    • 0001162208 scopus 로고
    • Guidelines for developmental toxicity risk assessment (EPA/600/FR-91/001)
    • U.S. EPA (U.S. Environmental Protection Agency), Available, accessed 24 November 2010
    • U.S. EPA (U.S. Environmental Protection Agency). 1991. Guidelines for developmental toxicity risk assessment (EPA/600/FR-91/001). Fed Reg 56(234):63798-63826.Available: http://www.epa.gov/raf/publications/guidelinesdev-toxicity-risk-assessment.htm [accessed 24 November 2010].
    • (1991) Fed Reg , vol.56 , Issue.234 , pp. 63798-63826
  • 28
    • 0000211484 scopus 로고    scopus 로고
    • Guidelines for reproductive toxicity risk assessment. EPA/630/R-96/0009
    • U.S. EPA (U.S. Environmental Protection Agency), Available, [accessed 24 November 2010]
    • U.S. EPA (U.S. Environmental Protection Agency). 1996. Guidelines for reproductive toxicity risk assessment. EPA/630/R-96/0009. Fed Reg 61(212):56274-56322. Available: http://www.epa.gov/raf/publications/guidelines-reproductive-tox-riskassessment.htm [accessed 24 November 2010].
    • (1996) Fed Reg , vol.61 , Issue.212 , pp. 56274-56322
  • 29
    • 79961059494 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency)., OPPTS 870.3100. 90-Day Oral Toxicity in Rodents. EPA 712- C-98-199. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 1998a. OPPTS 870.3100. 90-Day Oral Toxicity in Rodents. EPA 712- C-98-199. Washington, DC:U.S. EPA.
    • (1998)
  • 30
    • 79961089425 scopus 로고    scopus 로고
    • U.S. EPA (Environmental Protection Agency), OPPTS 870.3150. 90-Day Oral Toxicity in Nonrodents. Washington, DC:U.S. EPA
    • U.S. EPA (Environmental Protection Agency). 1998b. OPPTS 870.3150. 90-Day Oral Toxicity in Nonrodents. Washington, DC:U.S. EPA.
    • (1998)
  • 31
    • 79961089426 scopus 로고    scopus 로고
    • U.S. EPA (Environmental Protection Agency), OPPTS 870.3250. 90-Day Dermal Toxicity. Washington, DC:U.S. EPA
    • U.S. EPA (Environmental Protection Agency). 1998c. OPPTS 870.3250. 90-Day Dermal Toxicity. Washington, DC:U.S. EPA.
    • (1998)
  • 32
    • 79961098680 scopus 로고    scopus 로고
    • U.S. EPA (Environmental Protection Agency), OPPTS 870.3465. 90-Day Inhalation Toxicity. Washington, DC:U.S. EPA
    • U.S. EPA (Environmental Protection Agency). 1998d. OPPTS 870.3465. 90-Day Inhalation Toxicity. Washington, DC:U.S. EPA.
    • (1998)
  • 33
    • 79961049978 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), OPPTS 870.3700. Prenatal Developmental Toxicity Study. EPA 712-C-98-207. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 1998e. OPPTS 870.3700. Prenatal Developmental Toxicity Study. EPA 712-C-98-207. Washington, DC:U.S. EPA.
    • (1998)
  • 34
    • 79961033697 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), OPPTS 870.3800. Reproduction and Fertility Effects. EPA 712-C-98-208. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 1998f. OPPTS 870.3800. Reproduction and Fertility Effects. EPA 712-C-98-208. Washington, DC:U.S. EPA.
    • (1998)
  • 35
    • 79961061654 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), OPPTS 870.4100. Chronic Toxicity. EPA 712-C-98-210. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 1998g. OPPTS 870.4100. Chronic Toxicity. EPA 712-C-98-210. Washington, DC:U.S. EPA.
    • (1998)
  • 36
    • 79961066178 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), OPPTS 870.4200. Carcinogenicity. EPA 712-C-98-211. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 1998h. OPPTS 870.4200. Carcinogenicity. EPA 712-C-98-211. Washington, DC:U.S. EPA.
    • (1998)
  • 37
    • 79961051417 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), OPPTS 870.4300. Combined Chronic Toxicity/Carcinogenicity. EPA 712-C-9-212. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 1998i. OPPTS 870.4300. Combined Chronic Toxicity/Carcinogenicity. EPA 712-C-9-212. Washington, DC:U.S. EPA.
    • (1998)
  • 38
    • 79961048606 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency)., OPPTS 870.6300. Developmental Neurotoxicity Study. EPA 712-C-98-239. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 1998j. OPPTS 870.6300. Developmental Neurotoxicity Study. EPA 712-C-98-239. Washington, DC:U.S. EPA.
    • (1998)
  • 39
    • 79961086477 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), OPPTS 870.3050. Repeated Dose 28-Day Oral Toxicity Study in Rodents. EPA 712-C-00-366. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 2000a. OPPTS 870.3050. Repeated Dose 28-Day Oral Toxicity Study in Rodents. EPA 712-C-00-366. Washington, DC:U.S. EPA.
    • (2000)
  • 40
    • 79961071033 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), OPPTS 870.3550. Reproduction/Developmental Toxicity Screening Test. EPA 712-C-00-368. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 2000b. OPPTS 870.3550. Reproduction/Developmental Toxicity Screening Test. EPA 712-C-00-368. Washington, DC:U.S. EPA.
    • (2000)
  • 41
    • 79961044123 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), OPPTS 870.3650. Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test. EPA 712-C-98-207. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 2000c. OPPTS 870.3650. Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test. EPA 712-C-98-207. Washington, DC:U.S. EPA.
    • (2000)
  • 42
    • 79961037568 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency)., OPPTS 870.8355. Combined Chronic Toxicity/Carcinogenicity Testing of Respirable Fibrous Particles. EPA 712-C-01-352. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 2001. OPPTS 870.8355. Combined Chronic Toxicity/Carcinogenicity Testing of Respirable Fibrous Particles. EPA 712-C-01-352. Washington, DC:U.S. EPA.
    • (2001)
  • 43
    • 84856310644 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency)., Guidelines for Carcinogen Risk Assessment. EPA/630/P-03/001F. Washington, DC:U.S. EPA. Available, accessed 24 November 2010
    • U.S. EPA (U.S. Environmental Protection Agency). 2005a. Guidelines for Carcinogen Risk Assessment. EPA/630/P-03/001F. Washington, DC:U.S. EPA. Available: http://iaspub.epa.gov/eims/eimscomm.getfile?p_download_id=439797 [accessed 24 November 2010].
    • (2005)
  • 44
    • 33645229436 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), EPA/630/R-03/003F. Washington, DC:U.S. EPA. Available, [accessed 24 November 2010]
    • U.S. EPA (U.S. Environmental Protection Agency). 2005b. Supplemental Guidance for Assessing Susceptibility from Early-Life Exposure to Carcinogens. EPA/630/R-03/003F. Washington, DC:U.S. EPA. Available: http://iaspub.epa.gov/eims/eimscomm.getfile?p_download_id=459042 [accessed 24 November 2010].
    • (2005) Supplemental Guidance For Assessing Susceptibility From Early-Life Exposure to Carcinogens
  • 45
    • 79961070720 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), OPPTS 890.1400. Hershberger Bioassay. EPA 740-C-09-008. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 2009a. OPPTS 890.1400. Hershberger Bioassay. EPA 740-C-09-008. Washington, DC:U.S. EPA.
    • (2009)
  • 46
    • 79961064740 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), OPPTS 890.1450. Pubertal Development and Thyroid Function in Intact Juvenile/Peripubertal Female Rats. EPA 740-C-09-009. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 2009b. OPPTS 890.1450. Pubertal Development and Thyroid Function in Intact Juvenile/Peripubertal Female Rats. EPA 740-C-09-009. Washington, DC:U.S. EPA.
    • (2009)
  • 47
    • 79961070376 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), OPPTS 890.1500. Pubertal Development and Thyroid Function in Intact Juvenile/Peripubertal Male Rats. EPA 740-C-09-012. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 2009c. OPPTS 890.1500. Pubertal Development and Thyroid Function in Intact Juvenile/Peripubertal Male Rats. EPA 740-C-09-012. Washington, DC:U.S. EPA.
    • (2009)
  • 48
    • 79961035756 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency)., OPPTS 890.1600. Uterotrophic Assay. EPA 740-C-09-010. Washington, DC:U.S. EPA
    • U.S. EPA (U.S. Environmental Protection Agency). 2009d. OPPTS 890.1600. Uterotrophic Assay. EPA 740-C-09-010. Washington, DC:U.S. EPA.
    • (2009)
  • 49
    • 84856312460 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), Assay Development and Validation. Washington, DC:U.S. EPA. Available, accessed 24 November 2010
    • U.S. EPA (U.S. Environmental Protection Agency). 2010a. Endocrine Disruptor Screening Program (EDSP), Assay Development and Validation. Washington, DC:U.S. EPA. Available: http://www.epa.gov/scipoly/oscpendo/pubs/assayvalidation [accessed 24 November 2010].
    • (2010) Endocrine Disruptor Screening Program (EDSP)
  • 50
    • 84856310970 scopus 로고    scopus 로고
    • U.S. EPA (U.S. Environmental Protection Agency), Available, accessed 15 June 2011
    • U.S. EPA (U.S. Environmental Protection Agency). 2010b. Harmonized Test Guidelines. Available: http://epa.gov/ocspp/pubs/frs/home/guidelin.htm [accessed 15 June 2011].
    • (2010) Harmonized Test Guidelines
  • 51
    • 79961011894 scopus 로고    scopus 로고
    • Gestational and chronic low-dose PFOA exposures and mammary gland growth and differentiation in three generations of CD-1 mice
    • White SS, Stanko JP, Kato K, Calafat AM, Hines EP, Fenton SE. 2011. Gestational and chronic low-dose PFOA exposures and mammary gland growth and differentiation in three generations of CD-1 mice. Environ Health Perspect 119:1070-1076.
    • (2011) Environ Health Perspect , vol.119 , pp. 1070-1076
    • White, S.S.1    Stanko, J.P.2    Kato, K.3    Calafat, A.M.4    Hines, E.P.5    Fenton, S.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.