-
1
-
-
0034641709
-
+ cell proliferation: BCR/ABL up-regulates the cyclin-dependent kinase inhibitor p27Kip which is relocated to the cell cytoplasm and incapable of regulating cdk2 activity
-
USA
-
+ cell proliferation: BCR/ABL up-regulates the cyclin-dependent kinase inhibitor, p27Kip, which is relocated to the cell cytoplasm and incapable of regulating cdk2 activity. Proc. Natl Acad. Sci. USA 97(19), 10538-10543 (2000).
-
(2000)
Proc. Natl Acad. Sci.
, vol.97
, Issue.19
, pp. 10538-10543
-
-
Jiang, Y.1
Zhao, R.C.2
Verfaillie, C.M.3
-
2
-
-
0023270373
-
Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukemia
-
DOI 10.1038/328342a0
-
Gordon MY, Dowding CR, Riley GP, Goldman JM, Greaves MF. Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia. Nature 328(6128), 342-344 (1987). (Pubitemid 17097654)
-
(1987)
Nature
, vol.328
, Issue.6128
, pp. 342-344
-
-
Gordon, M.Y.1
Dowding, C.R.2
Riley, G.P.3
-
3
-
-
0036463948
-
Perspectives on the development of a molecularly targeted agent
-
DOI 10.1016/S1535-6108(02)00025-9
-
Druker BJ. Perspectives on the development of a molecularly targeted agent. Cancer Cell 1(1), 31-36 (2002). (Pubitemid 41039173)
-
(2002)
Cancer Cell
, vol.1
, Issue.1
, pp. 31-36
-
-
Druker, B.J.1
-
4
-
-
76249087423
-
TGF-β-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia
-
Naka K, Hoshii T, Muraguchi T et al. TGF-β-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia. Nature 463(7281), 676-680 (2010).
-
(2010)
Nature
, vol.463
, Issue.7281
, pp. 676-680
-
-
Naka, K.1
Hoshii, T.2
Muraguchi, T.3
-
5
-
-
66449122303
-
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells including primary CML stem cells
-
Bellodi C, Lidonnici MR, Hamilton A et al. Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J. Clin. Invest. 119(5), 1109-1123 (2009).
-
(2009)
J. Clin. Invest.
, vol.119
, Issue.5
, pp. 1109-1123
-
-
Bellodi, C.1
Lidonnici, M.R.2
Hamilton, A.3
-
6
-
-
33750627972
-
A common signaling cascade may underlie "addiction" to the Src, BCR-ABL, and EGF receptor oncogenes
-
DOI 10.1016/j.ccr.2006.09.014, PII S1535610806002923
-
Sharma SV, Gajowniczek P, Way IP et al. A common signaling cascade may underlie ddiction to the Src, BCR-ABL, and EGF receptor oncogenes. Cancer Cell 10(5), 425-435 (2006). (Pubitemid 44693471)
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 425-435
-
-
Sharma, S.V.1
Gajowniczek, P.2
Way, I.P.3
Lee, D.Y.4
Jiang, J.5
Yuza, Y.6
Classon, M.7
Haber, D.A.8
Settleman, J.9
-
7
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
DOI 10.1038/sj.onc.1207521
-
Gozuacik D, Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 23(16), 2891-2906 (2004). (Pubitemid 38638851)
-
(2004)
Oncogene
, vol.23
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
8
-
-
57449120942
-
Autophagy-induced tumor dormancy in ovarian cancer
-
Amaravadi RK. Autophagy-induced tumor dormancy in ovarian cancer. J. Clin. Invest. 118(12), 3837-3840 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, Issue.12
, pp. 3837-3840
-
-
Amaravadi, R.K.1
-
9
-
-
35648950010
-
New concepts in antimalarial use and mode of action in dermatology
-
DOI 10.1111/j.1529-8019.2007.00131.x
-
Kalia S, Dutz JP. New concepts in antimalarial use and mode of action in dermatology. Dermatol. Ther. 20(4), 160-174 (2007). (Pubitemid 350029307)
-
(2007)
Dermatologic Therapy
, vol.20
, Issue.4
, pp. 160-174
-
-
Kalia, S.1
Dutz, J.P.2
-
10
-
-
33749054651
-
Risks and benefits of chloroquine use in anticancer strategies
-
DOI 10.1016/S1470-2045(06)70875-0, PII S1470204506708750
-
Savarino A, Lucia MB, Giordano F, Cauda R. Risks and benefits of chloroquine use in anticancer strategies. Lancet Oncol. 7(10), 792-793 (2006). (Pubitemid 44464070)
-
(2006)
Lancet Oncology
, vol.7
, Issue.10
, pp. 792-793
-
-
Savarino, A.1
Lucia, M.B.2
Giordano, F.3
Cauda, R.4
-
11
-
-
0038677510
-
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine
-
DOI 10.1038/sj.onc.1206622
-
Boya P, Gonzalez-Polo RA, Poncet D et al. Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. Oncogene 22(25), 3927-3936 (2003). (Pubitemid 36819666)
-
(2003)
Oncogene
, vol.22
, Issue.25
, pp. 3927-3936
-
-
Boya, P.1
Gonzalez-Polo, R.-A.2
Poncet, D.3
Andreau, K.4
Vieira, H.L.A.5
Roumier, T.6
Perfettini, J.-L.7
Kroemer, G.8
-
12
-
-
77954653486
-
Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells
-
Kim EL, Wustenberg R, Rubsam A et al. Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells. Neuro. Oncol. 12(4), 389-400 (2010).
-
(2010)
Neuro. Oncol.
, vol.12
, Issue.4
, pp. 389-400
-
-
Kim, E.L.1
Wustenberg, R.2
Rubsam, A.3
-
13
-
-
0034815663
-
Chloroquine-induced neuronal cell death is p53 and Bcl-2 family-dependent but caspase-independent
-
Zaidi AU, McDonough JS, Klocke BJ et al. Chloroquine-induced neuronal cell death is p53 and Bcl-2 family-dependent βut caspase-independent. J. Neuropathol. Exp. Neurol. 60(10), 937-945 (2001). (Pubitemid 32924119)
-
(2001)
Journal of Neuropathology and Experimental Neurology
, vol.60
, Issue.10
, pp. 937-945
-
-
Zaidi, A.U.1
Mcdonough, J.S.2
Klocke, B.J.3
Latham, C.B.4
Korsmeyer, S.J.5
Flavell, R.A.6
Schmidt, R.E.7
Roth, K.A.8
-
14
-
-
20444393495
-
Tyrosine kinase inhibitor resistance in cancer: Role of ABC multidrug transporters
-
DOI 10.1016/j.drup.2005.02.002, PII S136876460500018X
-
Ozvegy-Laczka C, Cserepes J, Elkind NB, Sarkadi B. Tyrosine kinase inhibitor resistance in cancer: role of ABC multidrug transporters. Drug Resist. Updat. 8(1-2), 15-26 (2005). (Pubitemid 40797953)
-
(2005)
Drug Resistance Updates
, vol.8
, Issue.1-2
, pp. 15-26
-
-
Ozvegy-Laczka, C.1
Cserepes, J.2
Elkind, N.B.3
Sarkadi, B.4
-
15
-
-
0033044368
-
Dose-loading with hydroxychloroquine improves the rate of response in early, active rheumatoid arthritis: A randomized, double-blind six-week trial with eighteen-week extension
-
DOI 10.1002/1529-0131(199902)42:2<357::AID-ANR19>3.0.CO;2-J
-
Furst DE, Lindsley H, Baethge B et al. Dose-loading with hydroxychloroquine improves the rate of response in early, active rheumatoid arthritis: a randomized, double-blind six-week trial with eighteen-week extension. Arthritis Rheum. 42(2), 357-365 (1999). (Pubitemid 29072854)
-
(1999)
Arthritis and Rheumatism
, vol.42
, Issue.2
, pp. 357-365
-
-
Furst, D.E.1
Lindsley, H.2
Baethge, B.3
Botstein, G.R.4
Caldwell, J.5
Dietz, F.6
Ettlinger, R.7
Golden, H.E.8
McLaughlin, G.E.9
Moreland, L.W.10
Neal Roberts, W.11
Rooney, T.W.12
Rothschild, B.13
Sack, M.14
Sebba, A.I.15
Weisman, M.16
Welch, K.E.17
Yocum, D.18
-
16
-
-
0036272067
-
Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritis
-
DOI 10.1002/art.10307
-
Munster T, Gibbs JP, Shen D et al. Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritis. Arthritis Rheum. 46(6), 1460-1469 (2002). (Pubitemid 34620191)
-
(2002)
Arthritis and Rheumatism
, vol.46
, Issue.6
, pp. 1460-1469
-
-
Munster, T.1
Gibbs, J.P.2
Shen, D.3
Baethge, B.A.4
Botstein, G.R.5
Caldwell, J.6
Dietz, F.7
Ettlinger, R.8
Golden, H.E.9
Lindsley, H.10
McLaughlin, G.E.11
Moreland, L.W.12
Roberts, W.N.13
Rooney, T.W.14
Rothschild, B.15
Sack, M.16
Sebba, A.I.17
Weisman, M.18
Welch, K.E.19
Yocum, D.20
Furst, D.E.21
more..
-
17
-
-
77649185396
-
Bortezomib induces autophagic death in proliferating human endothelial cells
-
Belloni D, Veschini L, Foglieni C et al. Bortezomib induces autophagic death in proliferating human endothelial cells. Exp. Cell Res. 316(6), 1010-1018 (2010).
-
(2010)
Exp. Cell Res.
, vol.316
, Issue.6
, pp. 1010-1018
-
-
Belloni, D.1
Veschini, L.2
Foglieni, C.3
-
18
-
-
78649305851
-
FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy
-
Zhang N, Qi Y, Wadham C et al. FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: a protective role of autophagy. Autophagy 6(8), 1157-1167 (2010).
-
(2010)
Autophagy
, vol.6
, Issue.8
, pp. 1157-1167
-
-
Zhang, N.1
Qi, Y.2
Wadham, C.3
-
19
-
-
54349129547
-
Autophagy induced by farnesyltransferase inhibitors in cancer cells
-
Pan J, Chen B, Su CH et al. Autophagy induced by farnesyltransferase inhibitors in cancer cells. Cancer Biol. Ther. 7(10), 1679-1684 (2008).
-
(2008)
Cancer Biol. Ther.
, vol.7
, Issue.10
, pp. 1679-1684
-
-
Pan, J.1
Chen, B.2
Su, C.H.3
|