Apa antigen of Mycobacterium avium subsp. paratuberculosis as a target for species-specific immunodetection of the bacteria in infected tissues of cattle with paratuberculosis

Veterinary Immunology and Immunopathology

Volumn 143, Issue 1-2, 2011, Pages 75-82

  Souza, Giliane S ^a   Rodrigues, Ana Bárbara F ^a   Gioffré, Andrea ^b   Romano, Maria I ^b   Carvalho, Eulógio C Q ^a   Ventura, Thatiana L B ^a   Lasunskaia, Elena B ^a  

^a UNIVERSIDADE ESTADUAL DO NORTE FLUMINENSE DARCY RIBEIRO   (Brazil)

^b INSTITUTO NACIONAL DE TECNOLOGÍA AGROPECUARIA INTA   (Argentina)

Author keywords

Antigen Apa; Immunodetection; M. avium subsp. paratuberculosis; Monoclonal antibodies; Paratuberculosis

Indexed keywords

APA PROTEIN; MONOCLONAL ANTIBODY; MYCOBACTERIUM ANTIGEN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIUM DETECTION; CATTLE; IMMUNODETECTION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MACROPHAGE; MOUSE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM PARATUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PARATUBERCULOSIS; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CATTLE; CATTLE DISEASES; FLUORESCENT ANTIBODY TECHNIQUE; GENES, BACTERIAL; MACROPHAGES; MICE; MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS; PARATUBERCULOSIS; SPECIES SPECIFICITY;

BOS; BOVINAE; CORYNEBACTERINEAE; MYCOBACTERIUM; MYCOBACTERIUM AVIUM; MYCOBACTERIUM AVIUM COMPLEX; MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 79961030880     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2011.06.026     Document Type: Article

References (14)

1. Cousins D., Whittington R., Marsh I., Masters A., Evans R., Kluver P. Mycobacteria distinct from Mycobacterium avium subsp. paratuberculosis isolated from the faeces of ruminants possess IS900-like sequences detectable by IS900 polymerase chain reaction: implications for diagnosis. Mol. Cell Probes 1999, 13:431-442.
2. Delgado F., Etchechoury D., Gioffré A., Paolicchi F., Blanco Viera F., Mundo S., Romano M.I. Comparison between two in situ methods for Mycobacterium avium subsp. paratuberculosis detection in tissue samples from infected cattle. Vet. Microbiol. 2009, 134:383-387.
3. Gioffré A., Echeverria-Valencia G., Arese A., Morsella C., Garbaccio S., Delgado F., Zumárraga M., Paolicchi F., Cataldi A., Romano M.I. Characterization of the Apa antigen from M. avium subsp. paratuberculosis: a conserved Mycobacterium antigen that elicits a strong humoral response in cattle. Vet. Immunol. Immunopathol. 2009, 132:199-208.
4. Horn C., Pescher P., Romain F., Marchal G. Characterization of murine monoclonal antibodies specific for the 45/47kDa antigen complex (APA) of Mycobacterium tuberculosis, M. bovis and BCG. J. Immunol. Methods 1996, 197:151-159.
5. Khan F.A., Chaudhry Z.I., Ali M.I., Khan S., Mumtaz N., Ahmad I. Detection of Mycobacterium avium subsp. paratuberculosis in tissue samples of cattle and buffaloes. Trop. Anim. Health Prod. 2010, 42:633-638.
6. Martinson S.A., Hanna P.E., Ikede B.O., Lewis J.P., Miller L.M., Keefe G.P., McKenna S.L. Comparison of bacterial culture, histopathology, and immunohistochemistry for the diagnosis of Johne's disease in culled dairy cows. J. Vet. Diagn. Invest. 2008, 20:51-57.
7. Oliveira R.S., Sircili M.P., Oliveira E.M., Balian S.C., Ferreira-Neto J.S., Leao S.C. Identification of Mycobacterium avium genotypes with distinctive traits by combination of IS1245-based restriction fragment length polymorphism and restriction analysis of hsp65. J. Clin. Microbiol. 2003, 41:44-49.
8. Ristow P., Marassi C.D., Rodrigues A.B., Oelemann W.M., Rocha F., Santos A.S., Carvalho E.C., Carvalho C.B., Ferreira R., Fonseca L.S., Lilenbaum W. Diagnosis of paratuberculosis in a dairy herd native to Brazil. Vet. J. 2007, 174:432-434.
9. Rodrigues, A.F.B., 2005. Paratuberculosis in cattle: anatomy-clinical, bacteriological, immunohistochemical and PCR analysis. PhD thesis. Universidade Estadual do Norte Fluminense, Campos, Rio de Janeiro, Brazil.
10. Romain F., Laqueyrerie A., Militzer P., Pescher P., Chavarot P., Lagranderie M., Auregan G., Gheorghiu M., Marchal G. Identification of a Mycobacterium bovis BCG 45/47-kilodalton antigen complex, an immunodominant target for antibody response after immunization with living bacteria. Infect. Immun. 1993, 61:742-750.
11. Schorey J.S., Holsti M.A., Ratliff T.L., Allen P.M., Brown E.J. Characterization of the fibronectin-attachment protein of Mycobacterium avium reveals a fibronectin-binding motif conserved among mycobacteria. Mol. Microbiol. 1996, 21:321-329.
12. Secott T.E., Lin T.L., Wu C.C. Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein facilitates M-cell targeting and invasion through a fibronectin bridge with host integrins. Infect. Immun. 2004, 72:3724-3732.
13. Wieles B., van Agterveld M., Janson A., Clark-Curtiss J., Rinke de Wit T., Harboe M., Thole J. Characterization of a Mycobacterium leprae antigen related to the secreted Mycobacterium tuberculosis protein MPT32. Infect. Immun. 1994, 62:252-258.
14. Wu C.C., Secott T., Lin T.L. Identification and subspeciation of Mycobacterium avium complex isolates by PCR amplification of a fibronectin-attachment protein gene element. Proc. 8th Int. Colloq. Paratuberc., Denmark 2005, 438-442. http://pubs.paratuberculosis.org/index.php/paratb/article/viewFile/352/172.